Details for: CACNA1B

Gene ID: 774

Symbol: CACNA1B

Ensembl ID: ENSG00000148408

Description: calcium voltage-gated channel subunit alpha1 B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 120.4902
    Cell Significance Index: -48.9500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 5.7624
    Cell Significance Index: 2066.8800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 5.2093
    Cell Significance Index: 230.4200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 4.9072
    Cell Significance Index: 185.8300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 4.6354
    Cell Significance Index: 132.2800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 3.9943
    Cell Significance Index: 268.5800
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 3.5926
    Cell Significance Index: 46.5900
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 3.3379
    Cell Significance Index: 34.7700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.3378
    Cell Significance Index: 669.5600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 3.1677
    Cell Significance Index: 75.9700
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 2.9244
    Cell Significance Index: 39.0100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 2.8677
    Cell Significance Index: 176.2600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.7860
    Cell Significance Index: 1926.8900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.7854
    Cell Significance Index: 60.9900
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.1910
    Cell Significance Index: 16.8100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.4090
    Cell Significance Index: 5.1000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2410
    Cell Significance Index: 4.1300
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.2047
    Cell Significance Index: 1.6900
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.1261
    Cell Significance Index: 1.2000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.0486
    Cell Significance Index: 0.5300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.0112
    Cell Significance Index: 0.2300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.0010
    Cell Significance Index: 0.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0122
    Cell Significance Index: -22.9900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0176
    Cell Significance Index: -32.4500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0207
    Cell Significance Index: -28.1700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0215
    Cell Significance Index: -33.1000
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0293
    Cell Significance Index: -0.3700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0504
    Cell Significance Index: -37.3000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0753
    Cell Significance Index: -57.0100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0774
    Cell Significance Index: -49.1600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0810
    Cell Significance Index: -45.6900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0959
    Cell Significance Index: -52.3500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0998
    Cell Significance Index: -62.3200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1018
    Cell Significance Index: -46.1900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1381
    Cell Significance Index: -4.5200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1466
    Cell Significance Index: -42.1800
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1750
    Cell Significance Index: -4.3600
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.1800
    Cell Significance Index: -2.1000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1814
    Cell Significance Index: -5.0700
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.2060
    Cell Significance Index: -2.6000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2108
    Cell Significance Index: -9.1700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2182
    Cell Significance Index: -6.9500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2381
    Cell Significance Index: -3.4100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.2412
    Cell Significance Index: -47.8600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2420
    Cell Significance Index: -13.5800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2480
    Cell Significance Index: -52.2300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.2502
    Cell Significance Index: -45.1000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2841
    Cell Significance Index: -6.0300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2958
    Cell Significance Index: -6.3900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.3086
    Cell Significance Index: -52.7000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3231
    Cell Significance Index: -46.9600
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.3524
    Cell Significance Index: -3.3400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.3757
    Cell Significance Index: -51.5900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.3780
    Cell Significance Index: -46.4800
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.3863
    Cell Significance Index: -4.6200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.4899
    Cell Significance Index: -57.0900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4912
    Cell Significance Index: -51.1500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.5005
    Cell Significance Index: -38.4100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5090
    Cell Significance Index: -58.3200
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.5592
    Cell Significance Index: -6.1700
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.6631
    Cell Significance Index: -16.5400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6893
    Cell Significance Index: -36.1900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.7253
    Cell Significance Index: -25.4100
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.8332
    Cell Significance Index: -17.3900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.9107
    Cell Significance Index: -57.4000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.9367
    Cell Significance Index: -48.7900
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.9933
    Cell Significance Index: -6.7300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.0667
    Cell Significance Index: -13.2300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.0814
    Cell Significance Index: -50.8300
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -1.0837
    Cell Significance Index: -14.4500
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: -1.0978
    Cell Significance Index: -8.6100
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -1.1007
    Cell Significance Index: -21.9500
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -1.1386
    Cell Significance Index: -22.4100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.1583
    Cell Significance Index: -42.5200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -1.1729
    Cell Significance Index: -20.2800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -1.3461
    Cell Significance Index: -47.3000
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -1.3462
    Cell Significance Index: -13.5600
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -1.3726
    Cell Significance Index: -8.9300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.4016
    Cell Significance Index: -72.8100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.4371
    Cell Significance Index: -36.9400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.4394
    Cell Significance Index: -67.1100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -1.4970
    Cell Significance Index: -34.5900
  • Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
    Fold Change: -1.6180
    Cell Significance Index: -16.6400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -1.6330
    Cell Significance Index: -47.0500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.7048
    Cell Significance Index: -36.4400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -1.7775
    Cell Significance Index: -56.2200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.8106
    Cell Significance Index: -45.2600
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -1.8297
    Cell Significance Index: -37.2300
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -1.8321
    Cell Significance Index: -45.7600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.8370
    Cell Significance Index: -52.6600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.9333
    Cell Significance Index: -50.8400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -1.9920
    Cell Significance Index: -53.1900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -2.0008
    Cell Significance Index: -53.5200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -2.0192
    Cell Significance Index: -59.4800
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -2.0296
    Cell Significance Index: -49.5200
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -2.0341
    Cell Significance Index: -51.8300
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -2.0889
    Cell Significance Index: -29.2100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -2.1459
    Cell Significance Index: -46.4900
  • Cell Name: interneuron (CL0000099)
    Fold Change: -2.1677
    Cell Significance Index: -25.3200
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -2.1738
    Cell Significance Index: -15.0800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Voltage-gated calcium channel**: The CACNA1B gene encodes for the alpha1B subunit of voltage-gated calcium channels, which are critical for the influx of calcium ions into neurons. 2. **Neuronal expression**: The alpha1B subunit is highly expressed in various neuronal populations, including inhibitory interneurons, Purkinje cells, and pyramidal neurons. 3. **Synaptic transmission**: The alpha1B subunit is involved in the modulation of synaptic transmission, particularly in the regulation of neurotransmitter release. 4. **Amyloid-beta binding**: The alpha1B subunit has been shown to interact with amyloid-beta, a peptide implicated in Alzheimer's disease. **Pathways and Functions:** 1. **Calcium ion import**: The alpha1B subunit regulates calcium ion import across the plasma membrane, which is essential for neuronal function and synaptic plasticity. 2. **Neuronal excitability**: The alpha1B subunit modulates neuronal excitability by regulating calcium influx into neurons. 3. **Synaptic plasticity**: The alpha1B subunit is involved in the regulation of synaptic plasticity, particularly in the context of long-term potentiation (LTP) and long-term depression (LTD). 4. **Neurotransmitter release**: The alpha1B subunit regulates neurotransmitter release by modulating the activity of voltage-gated calcium channels. **Clinical Significance:** 1. **Alzheimer's disease**: The alpha1B subunit has been implicated in Alzheimer's disease, particularly in the context of amyloid-beta binding and synaptic dysfunction. 2. **Schizophrenia**: The alpha1B subunit has been linked to schizophrenia, particularly in the context of synaptic dysfunction and neuronal excitability. 3. **Mood disorders**: The alpha1B subunit has been implicated in mood disorders, particularly in the context of synaptic plasticity and neuronal excitability. 4. **Neurodevelopmental disorders**: The alpha1B subunit has been linked to neurodevelopmental disorders, particularly in the context of synaptic dysfunction and neuronal excitability. In conclusion, the CACNA1B gene plays a critical role in regulating calcium signaling and neuronal function. Its dysregulation has been implicated in various neurological disorders, including Alzheimer's disease, schizophrenia, mood disorders, and neurodevelopmental disorders. Further research is necessary to fully elucidate the mechanisms underlying the CACNA1B gene and its role in human disease.

Genular Protein ID: 3918820872

Symbol: CAC1B_HUMAN

Name: Voltage-dependent N-type calcium channel subunit alpha-1B

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1321501

Title: Structure and functional expression of an omega-conotoxin-sensitive human N-type calcium channel.

PubMed ID: 1321501

DOI: 10.1126/science.1321501

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 9030575

Title: Isolation and characterization of the 5'-upstream region of the human N-type calcium channel alpha1B subunit gene. Chromosomal localization and promoter analysis.

PubMed ID: 9030575

DOI: 10.1074/jbc.272.8.5098

PubMed ID: 25296916

Title: CACNA1B mutation is linked to unique myoclonus-dystonia syndrome.

PubMed ID: 25296916

DOI: 10.1093/hmg/ddu513

PubMed ID: 26157024

Title: The CACNA1B R1389H variant is not associated with myoclonus-dystonia in a large European multicentric cohort.

PubMed ID: 26157024

DOI: 10.1093/hmg/ddv255

PubMed ID: 30982612

Title: Bi-allelic loss-of-function CACNA1B mutations in progressive epilepsy-dyskinesia.

PubMed ID: 30982612

DOI: 10.1016/j.ajhg.2019.03.005

PubMed ID: 34234349

Title: Structure of human Cav2.2 channel blocked by the painkiller ziconotide.

PubMed ID: 34234349

DOI: 10.1038/s41586-021-03699-6

Sequence Information:

  • Length: 2339
  • Mass: 262496
  • Checksum: 17A45C6D1E76B39D
  • Sequence:
  • MVRFGDELGG RYGGPGGGER ARGGGAGGAG GPGPGGLQPG QRVLYKQSIA QRARTMALYN 
    PIPVKQNCFT VNRSLFVFSE DNVVRKYAKR ITEWPPFEYM ILATIIANCI VLALEQHLPD 
    GDKTPMSERL DDTEPYFIGI FCFEAGIKII ALGFVFHKGS YLRNGWNVMD FVVVLTGILA 
    TAGTDFDLRT LRAVRVLRPL KLVSGIPSLQ VVLKSIMKAM VPLLQIGLLL FFAILMFAII 
    GLEFYMGKFH KACFPNSTDA EPVGDFPCGK EAPARLCEGD TECREYWPGP NFGITNFDNI 
    LFAILTVFQC ITMEGWTDIL YNTNDAAGNT WNWLYFIPLI IIGSFFMLNL VLGVLSGEFA 
    KERERVENRR AFLKLRRQQQ IERELNGYLE WIFKAEEVML AEEDRNAEEK SPLDVLKRAA 
    TKKSRNDLIH AEEGEDRFAD LCAVGSPFAR ASLKSGKTES SSYFRRKEKM FRFFIRRMVK 
    AQSFYWVVLC VVALNTLCVA MVHYNQPRRL TTTLYFAEFV FLGLFLTEMS LKMYGLGPRS 
    YFRSSFNCFD FGVIVGSVFE VVWAAIKPGS SFGISVLRAL RLLRIFKVTK YWSSLRNLVV 
    SLLNSMKSII SLLFLLFLFI VVFALLGMQL FGGQFNFQDE TPTTNFDTFP AAILTVFQIL 
    TGEDWNAVMY HGIESQGGVS KGMFSSFYFI VLTLFGNYTL LNVFLAIAVD NLANAQELTK 
    DEEEMEEAAN QKLALQKAKE VAEVSPMSAA NISIAARQQN SAKARSVWEQ RASQLRLQNL 
    RASCEALYSE MDPEERLRFA TTRHLRPDMK THLDRPLVVE LGRDGARGPV GGKARPEAAE 
    APEGVDPPRR HHRHRDKDKT PAAGDQDRAE APKAESGEPG AREERPRPHR SHSKEAAGPP 
    EARSERGRGP GPEGGRRHHR RGSPEEAAER EPRRHRAHRH QDPSKECAGA KGERRARHRG 
    GPRAGPREAE SGEEPARRHR ARHKAQPAHE AVEKETTEKE ATEKEAEIVE ADKEKELRNH 
    QPREPHCDLE TSGTVTVGPM HTLPSTCLQK VEEQPEDADN QRNVTRMGSQ PPDPNTIVHI 
    PVMLTGPLGE ATVVPSGNVD LESQAEGKKE VEADDVMRSG PRPIVPYSSM FCLSPTNLLR 
    RFCHYIVTMR YFEVVILVVI ALSSIALAAE DPVRTDSPRN NALKYLDYIF TGVFTFEMVI 
    KMIDLGLLLH PGAYFRDLWN ILDFIVVSGA LVAFAFSGSK GKDINTIKSL RVLRVLRPLK 
    TIKRLPKLKA VFDCVVNSLK NVLNILIVYM LFMFIFAVIA VQLFKGKFFY CTDESKELER 
    DCRGQYLDYE KEEVEAQPRQ WKKYDFHYDN VLWALLTLFT VSTGEGWPMV LKHSVDATYE 
    EQGPSPGYRM ELSIFYVVYF VVFPFFFVNI FVALIIITFQ EQGDKVMSEC SLEKNERACI 
    DFAISAKPLT RYMPQNRQSF QYKTWTFVVS PPFEYFIMAM IALNTVVLMM KFYDAPYEYE 
    LMLKCLNIVF TSMFSMECVL KIIAFGVLNY FRDAWNVFDF VTVLGSITDI LVTEIAETNN 
    FINLSFLRLF RAARLIKLLR QGYTIRILLW TFVQSFKALP YVCLLIAMLF FIYAIIGMQV 
    FGNIALDDDT SINRHNNFRT FLQALMLLFR SATGEAWHEI MLSCLSNQAC DEQANATECG 
    SDFAYFYFVS FIFLCSFLML NLFVAVIMDN FEYLTRDSSI LGPHHLDEFI RVWAEYDPAA 
    CGRISYNDMF EMLKHMSPPL GLGKKCPARV AYKRLVRMNM PISNEDMTVH FTSTLMALIR 
    TALEIKLAPA GTKQHQCDAE LRKEISVVWA NLPQKTLDLL VPPHKPDEMT VGKVYAALMI 
    FDFYKQNKTT RDQMQQAPGG LSQMGPVSLF HPLKATLEQT QPAVLRGARV FLRQKSSTSL 
    SNGGAIQNQE SGIKESVSWG TQRTQDAPHE ARPPLERGHS TEIPVGRSGA LAVDVQMQSI 
    TRRGPDGEPQ PGLESQGRAA SMPRLAAETQ PVTDASPMKR SISTLAQRPR GTHLCSTTPD 
    RPPPSQASSH HHHHRCHRRR DRKQRSLEKG PSLSADMDGA PSSAVGPGLP PGEGPTGCRR 
    ERERRQERGR SQERRQPSSS SSEKQRFYSC DRFGGREPPK PKPSLSSHPT SPTAGQEPGP 
    HPQGSGSVNG SPLLSTSGAS TPGRGGRRQL PQTPLTPRPS ITYKTANSSP IHFAGAQTSL 
    PAFSPGRLSR GLSEHNALLQ RDPLSQPLAP GSRIGSDPYL GQRLDSEASV HALPEDTLTF 
    EEAVATNSGR SSRTSYVSSL TSQSHPLRRV PNGYHCTLGL SSGGRARHSY HHPDQDHWC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.