Details for: CACNA1E

Gene ID: 777

Symbol: CACNA1E

Ensembl ID: ENSG00000198216

Description: calcium voltage-gated channel subunit alpha1 E

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 3.29
    Marker Score: 1,912
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 3.14
    Marker Score: 26,539
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.96
    Marker Score: 8,451
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 2.96
    Marker Score: 9,913
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.84
    Marker Score: 95,888
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.76
    Marker Score: 4,632
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.54
    Marker Score: 37,941
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.52
    Marker Score: 50,030
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.5
    Marker Score: 94,888
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 2.48
    Marker Score: 1,190
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.45
    Marker Score: 941
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.4
    Marker Score: 18,387
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.31
    Marker Score: 674
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.28
    Marker Score: 8,817
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 2.1
    Marker Score: 4,825
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.97
    Marker Score: 121,359
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.97
    Marker Score: 20,309
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 1.96
    Marker Score: 10,549
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.96
    Marker Score: 7,988
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.93
    Marker Score: 18,301
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.88
    Marker Score: 16,114
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.86
    Marker Score: 17,455
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.77
    Marker Score: 3,354
  • Cell Name: interneuron (CL0000099)
    Fold Change: 1.64
    Marker Score: 749
  • Cell Name: granule cell (CL0000120)
    Fold Change: 1.62
    Marker Score: 12,224
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.62
    Marker Score: 7,496
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.61
    Marker Score: 1,171
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.46
    Marker Score: 2,977
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.46
    Marker Score: 2,248
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.44
    Marker Score: 807
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.37
    Marker Score: 872
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.32
    Marker Score: 3,111
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.27
    Marker Score: 857
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.24
    Marker Score: 5,205
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.2
    Marker Score: 44,210
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.2
    Marker Score: 719
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.18
    Marker Score: 488
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.17
    Marker Score: 18,263
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4,814
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.1
    Marker Score: 4,568
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.1
    Marker Score: 504
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 1.07
    Marker Score: 3,078
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.04
    Marker Score: 798
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,812
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,037
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.99
    Marker Score: 510
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.99
    Marker Score: 1,093
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.98
    Marker Score: 464
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,407
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 0.95
    Marker Score: 4,985
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,413
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.94
    Marker Score: 376
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5,338
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.93
    Marker Score: 1,145
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.92
    Marker Score: 1,681
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.92
    Marker Score: 2,741
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.91
    Marker Score: 327
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,288
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.86
    Marker Score: 3,065
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,264
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 710
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.77
    Marker Score: 399
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.76
    Marker Score: 246
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.72
    Marker Score: 464
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7
    Marker Score: 180
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.69
    Marker Score: 330
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.68
    Marker Score: 447
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.66
    Marker Score: 297
  • Cell Name: glial cell (CL0000125)
    Fold Change: 0.66
    Marker Score: 723
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.64
    Marker Score: 202
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.64
    Marker Score: 8,541
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.64
    Marker Score: 799
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 0.64
    Marker Score: 194
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.63
    Marker Score: 2,633
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.63
    Marker Score: 375
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.62
    Marker Score: 161
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.62
    Marker Score: 491
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.61
    Marker Score: 405
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.59
    Marker Score: 2,081
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.57
    Marker Score: 150
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.56
    Marker Score: 234
  • Cell Name: meningeal macrophage (CL0000879)
    Fold Change: 0.56
    Marker Score: 157
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.55
    Marker Score: 175
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.55
    Marker Score: 630
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.51
    Marker Score: 5,146
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.49
    Marker Score: 218
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 0.49
    Marker Score: 3,256
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.48
    Marker Score: 774
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.48
    Marker Score: 10,255
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.48
    Marker Score: 1,144
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.46
    Marker Score: 402
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.46
    Marker Score: 186
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.44
    Marker Score: 428
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.37
    Marker Score: 374
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.37
    Marker Score: 1,059
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.37
    Marker Score: 181
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.35
    Marker Score: 353
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.28
    Marker Score: 6,319
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.28
    Marker Score: 158
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.28
    Marker Score: 162

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** CACNA1E belongs to the voltage-gated calcium channel (VGCC) family, consisting of a large pore and four transmembrane domains. 2. **Function:** The alpha1E subunit is a critical component of the R-type calcium channel, responsible for regulating calcium ion influx in response to depolarization. 3. **Expression:** CACNA1E is highly expressed in neurons, with significant levels found in brainstem motor neurons, retinal bipolar neurons, and cerebral cortex neurons. 4. **Regulation:** The alpha1E subunit is subject to regulation by various factors, including calcium/calmodulin, dihydropyridine receptors, and beta subunits. **Pathways and Functions:** 1. **Calcium Signaling:** CACNA1E plays a crucial role in regulating calcium ion influx across neuronal membranes, influencing various physiological processes, including neurotransmission, energy metabolism, and insulin secretion. 2. **Neurotransmission:** The alpha1E subunit is involved in the regulation of synaptic transmission, particularly at chemical synapses, where it modulates the release of neurotransmitters. 3. **Energy Metabolism:** CACNA1E is also involved in regulating energy metabolism, particularly in the context of neuronal activity, where it influences the production of ATP and the regulation of metabolic pathways. 4. **Insulin Secretion:** The alpha1E subunit is expressed in pancreatic beta cells and plays a role in regulating insulin secretion in response to glucose stimuli. **Clinical Significance:** 1. **Neurological Disorders:** Mutations in CACNA1E have been associated with various neurological disorders, including epilepsy, migraines, and Parkinson's disease. 2. **Neuropsychiatric Disorders:** Alterations in CACNA1E expression have also been linked to neuropsychiatric disorders, such as schizophrenia and bipolar disorder. 3. **Cardiovascular Disease:** The alpha1E subunit is also involved in regulating calcium ion influx in cardiac myocytes, where it plays a role in the development of cardiovascular disease. 4. **Cancer:** CACNA1E has been implicated in the development and progression of certain types of cancer, including breast and prostate cancer. In conclusion, CACNA1E plays a vital role in regulating calcium signaling, neurotransmission, energy metabolism, and insulin secretion. Its dysregulation has been implicated in various neurological and cardiovascular disorders, highlighting the importance of this gene in human health and disease. Further research is necessary to fully elucidate the functions and clinical significance of CACNA1E.

Genular Protein ID: 1597205708

Symbol: CAC1E_HUMAN

Name: Voltage-dependent R-type calcium channel subunit alpha-1E

UniProtKB Accession Codes:

Q15878 B1AM12 B1AM13 B1AM14 Q14580 Q14581

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChEBI 7 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 13 EMBL 7 EMDB 3 EPD 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 4 PIR 2 PRINTS 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 2 RefSeq 3 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7536609

Title: Molecular analysis and functional expression of the human type E neuronal Ca2+ channel alpha 1 subunit.

PubMed ID: 7536609

PubMed ID: 8071363

Title: Structure and functional characterization of neuronal alpha 1E calcium channel subtypes.

PubMed ID: 8071363

DOI: 10.1016/s0021-9258(17)31796-9

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15258581

Title: Mutations in EFHC1 cause juvenile myoclonic epilepsy.

PubMed ID: 15258581

DOI: 10.1038/ng1393

PubMed ID: 30343943

Title: De novo pathogenic variants in CACNA1E cause developmental and epileptic encephalopathy with contractures, macrocephaly, and dyskinesias.

PubMed ID: 30343943

DOI: 10.1016/j.ajhg.2018.09.006

PubMed ID: 18400181

Title: Crystal structure of the CaV2 IQ domain in complex with Ca2+/calmodulin: high-resolution mechanistic implications for channel regulation by Ca2+.

PubMed ID: 18400181

DOI: 10.1016/j.str.2008.01.011

Sequence Information:

  • Length: 2313
  • Mass: 261731
  • Checksum: CCC7F309C27C42F1
  • Sequence:
    • MARFGEAVVA RPGSGDGDSD QSRNRQGTPV PASGQAAAYK QTKAQRARTM ALYNPIPVRQ 
NCFTVNRSLF IFGEDNIVRK YAKKLIDWPP FEYMILATII ANCIVLALEQ HLPEDDKTPM 
SRRLEKTEPY FIGIFCFEAG IKIVALGFIF HKGSYLRNGW NVMDFIVVLS GILATAGTHF 
NTHVDLRTLR AVRVLRPLKL VSGIPSLQIV LKSIMKAMVP LLQIGLLLFF AILMFAIIGL 
EFYSGKLHRA CFMNNSGILE GFDPPHPCGV QGCPAGYECK DWIGPNDGIT QFDNILFAVL 
TVFQCITMEG WTTVLYNTND ALGATWNWLY FIPLIIIGSF FVLNLVLGVL SGEFAKERER 
VENRRAFMKL RRQQQIEREL NGYRAWIDKA EEVMLAEENK NAGTSALEVL RRATIKRSRT 
EAMTRDSSDE HCVDISSVGT PLARASIKSA KVDGVSYFRH KERLLRISIR HMVKSQVFYW 
IVLSLVALNT ACVAIVHHNQ PQWLTHLLYY AEFLFLGLFL LEMSLKMYGM GPRLYFHSSF 
NCFDFGVTVG SIFEVVWAIF RPGTSFGISV LRALRLLRIF KITKYWASLR NLVVSLMSSM 
KSIISLLFLL FLFIVVFALL GMQLFGGRFN FNDGTPSANF DTFPAAIMTV FQILTGEDWN 
EVMYNGIRSQ GGVSSGMWSA IYFIVLTLFG NYTLLNVFLA IAVDNLANAQ ELTKDEQEEE 
EAFNQKHALQ KAKEVSPMSA PNMPSIERDR RRRHHMSMWE PRSSHLRERR RRHHMSVWEQ 
RTSQLRKHMQ MSSQEALNRE EAPTMNPLNP LNPLSSLNPL NAHPSLYRRP RAIEGLALGL 
ALEKFEEERI SRGGSLKGDG GDRSSALDNQ RTPLSLGQRE PPWLARPCHG NCDPTQQEAG 
GGEAVVTFED RARHRQSQRR SRHRRVRTEG KESSSASRSR SASQERSLDE AMPTEGEKDH 
ELRGNHGAKE PTIQEERAQD LRRTNSLMVS RGSGLAGGLD EADTPLVLPH PELEVGKHVV 
LTEQEPEGSS EQALLGNVQL DMGRVISQSE PDLSCITANT DKATTESTSV TVAIPDVDPL 
VDSTVVHISN KTDGEASPLK EAEIREDEEE VEKKKQKKEK RETGKAMVPH SSMFIFSTTN 
PIRRACHYIV NLRYFEMCIL LVIAASSIAL AAEDPVLTNS ERNKVLRYFD YVFTGVFTFE 
MVIKMIDQGL ILQDGSYFRD LWNILDFVVV VGALVAFALA NALGTNKGRD IKTIKSLRVL 
RVLRPLKTIK RLPKLKAVFD CVVTSLKNVF NILIVYKLFM FIFAVIAVQL FKGKFFYCTD 
SSKDTEKECI GNYVDHEKNK MEVKGREWKR HEFHYDNIIW ALLTLFTVST GEGWPQVLQH 
SVDVTEEDRG PSRSNRMEMS IFYVVYFVVF PFFFVNIFVA LIIITFQEQG DKMMEECSLE 
KNERACIDFA ISAKPLTRYM PQNRHTFQYR VWHFVVSPSF EYTIMAMIAL NTVVLMMKYY 
SAPCTYELAL KYLNIAFTMV FSLECVLKVI AFGFLNYFRD TWNIFDFITV IGSITEIILT 
DSKLVNTSGF NMSFLKLFRA ARLIKLLRQG YTIRILLWTF VQSFKALPYV CLLIAMLFFI 
YAIIGMQVFG NIKLDEESHI NRHNNFRSFF GSLMLLFRSA TGEAWQEIML SCLGEKGCEP 
DTTAPSGQNE NERCGTDLAY VYFVSFIFFC SFLMLNLFVA VIMDNFEYLT RDSSILGPHH 
LDEFVRVWAE YDRAACGRIH YTEMYEMLTL MSPPLGLGKR CPSKVAYKRL VLMNMPVAED 
MTVHFTSTLM ALIRTALDIK IAKGGADRQQ LDSELQKETL AIWPHLSQKM LDLLVPMPKA 
SDLTVGKIYA AMMIMDYYKQ SKVKKQRQQL EEQKNAPMFQ RMEPSSLPQE IIANAKALPY 
LQQDPVSGLS GRSGYPSMSP LSPQDIFQLA CMDPADDGQF QERQSLEPEV SELKSVQPSN 
HGIYLPSDTQ EHAGSGRASS MPRLTVDPQV VTDPSSMRRS FSTIRDKRSN SSWLEEFSME 
RSSENTYKSR RRSYHSSLRL SAHRLNSDSG HKSDTHRSGG RERGRSKERK HLLSPDVSRC 
NSEERGTQAD WESPERRQSR SPSEGRSQTP NRQGTGSLSE SSIPSVSDTS TPRRSRRQLP 
PVPPKPRPLL SYSSLIRHAG SISPPADGSE EGSPLTSQAL ESNNACLTES SNSPHPQQSQ 
HASPQRYISE PYLALHEDSH ASDCGEEETL TFEAAVATSL GRSNTIGSAP PLRHSWQMPN 
GHYRRRRRGG PGPGMMCGAV NNLLSDTEED DKC

Genular Protein ID: 2342004387

Symbol: Q59FG1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59FG1

Database IDs:

ARBA 16 BioGRID-ORCS 1 CTD 1 ChEBI 2 DNASU 1 EMBL 2 GO 3 Gene3D 3 Genevisible 1 GenomeRNAi 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 2 PROSITE 2 PeptideAtlas 1 Pfam 3 RefSeq 3 RuleBase 1 SAM 3 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 1869
  • Mass: 211937
  • Checksum: 22262D31FB729EA0
  • Sequence:
    • AGTSALEVLR RATIKRSRTE AMTRDSSDEH CVDISSVGTP LARASIKSAK VDGVSYFRHK 
ERLLRISIRH MVKSQVFYWI VLSLVALNTA CVAIVHHNQP QWLTHLLYYA EFLFLGLFLL 
EMSLKMYGMG PRLYFHSSFN CFDFGVTVGS IFEVVWAIFR PGTSFGISVL RALRLLRIFK 
ITKYWASLRN LVVSLMSSMK SIISLLFLLF LFIVVFALLG MQLFGGRFNF NDGTPSANFD 
TFPAAIMTVF QILTGEDWNE VMYNGIRSQG GVSSGMWSAI YFIVLTLFGN YTLLNVFLAI 
AVDNLANAQE LTKDEQEEEE AFNQKHALQK AKEVSPMSAP NMPSIERDRR RRHHMSMWEP 
RSSHLRERRR RHHMSVWEQR TSQLRKHMQM SSQEALNREE APTMNPLNPL NPLSSLNPLN 
AHPSLYRRPR AIEGLALGLA LEKFEEERIS RGGSLKGDGG DRSSALDNQR TPLSLGQREP 
PWLARPCHGN CDPTQQEAGG GEAVVTFEDR ARHRQSQRRS RHRRVRTEGK ESSSASRSRS 
ASQERSLDEA MPTEGEKDHE LRGNHGAKEP TIQEERAQDL RRTNSLMVSR GSGLAGGLDE 
ADTPLVLPHP ELEVGKHVVL TEQEPEGSSE QALLGNVQLD MGRVISQSEP DLSCITANTD 
KATTESTSVT VAIPDVDPLV DSTVVHISNK TDGEASPLKE AEIREDEEEV EKKKQKKEKR 
ETGKAMVPHS SMFIFSTTNP IRRACHYIVN LRYFEMCILL VIAASSIALA AEDPVLTNSE 
RNKVLRYFDY VFTGVFTFEM VIKMIDQGLI LQDGSYFRDL WNILDFVVVV GALVAFALAN 
ALGTNKGRDI KTIKSLRVLR VLRPLKTIKR LPKLKAVFDC VVTSLKNVFN ILIVYKLFMF 
IFAVIAVQLF KGKFFYCTDS SKDTEKECIG NYVDHEKNKM EVKGREWKRH EFHYDNIIWA 
LLTLFTVSTG EGWPQVLQHS VDVTEEDRGP SRSNRMEMSI FYVVYFVVFP FFFVNIFVAL 
IIITFQEQGD KMMEECSLEK NERACIDFAI SAKPLTRYMP QNRHTFQYRV WHFVVSPSFE 
YTIMAMIALN TVVLMMKYYS APCTYELALK YLNIAFTMVF SLECVLKVIA FGFLNYFRDT 
WNIFDFITVI GSITEIILTD SKLVNTSGFN MSFLKLFRAA RLIKLLRQGY TIRILLWTFV 
QSFKALPYVC LLIAMLFFIY AIIGMQVFGN IKLDEESHIN RHNNFRSFFG SLMLLFRSAT 
GEAWQEIMLS CLGEKGCEPD TTAPSGQNEN ERCGTDLAYV YFVSFIFFCS FLMLNLFVAV 
IMDNFEYLTR DSSILGPHHL DEFVRVWAEY DRAACGRIHY TEMYEMLTLM SPPLGLGKRC 
PSKVAYKRLV LMNMPVAEDM TVHFTSTLMA LIRTALDIKI AKGGADRQQL DSELQKETLA 
IWPHLSQKML DLLVPMPKAS DLTVGKIYAA MMIMDYYKQS KVKKQRQQLE EQKNAPMFQR 
MEPSSLPQEI IANAKALPYL QQDPVSGLSG RSGYPSMSPL SPQDIFQLAC MDPTDDGQFQ 
ERQSLVVTDP SSMRRSFSTI RDKRSNSSWL EEFSMERSSE NTYKSRRRSY HSSLRLSAHR 
LNSDSGHKSD THRSGGRERG RSKERKHLLS PDVSRCNSEE RGTQADWESP ERRQSRSPSE 
GRSQTPNRQG TGSLSESSIP SVSDTSTPRR SRRQLPPVPP KPRPLLSYSS LIRHAGSISP 
PADGSEEGSP LTSQALESNN ACLTESSNSP HPQQSQHASP QRYISEPYLA LHEDSHASDC 
GEEETLTFEA AVATSLGRSN TIGSAPPLRH SWQMPNGHYR RRRRGGPGPG MMCGAVNNLL 
SDTEEDDKC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.