Details for: CACNB2

Gene ID: 783

Symbol: CACNB2

Ensembl ID: ENSG00000165995

Description: calcium voltage-gated channel auxiliary subunit beta 2

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 9.63
    Marker Score: 170,990
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 5.28
    Marker Score: 117,908
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 5.08
    Marker Score: 2,279
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 5.08
    Marker Score: 2,753
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 4.85
    Marker Score: 2,700
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 4.61
    Marker Score: 3,036
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 4.5
    Marker Score: 1,486
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 3.94
    Marker Score: 2,036
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 3.89
    Marker Score: 13,839
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 3.6
    Marker Score: 21,640
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.5
    Marker Score: 7,680
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.25
    Marker Score: 13,600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 3.21
    Marker Score: 938
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 3.13
    Marker Score: 1,651
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 3.08
    Marker Score: 65,761
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.98
    Marker Score: 8,497
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.89
    Marker Score: 4,848
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.83
    Marker Score: 21,701
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.74
    Marker Score: 40,968
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.73
    Marker Score: 861
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.7
    Marker Score: 102,438
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.7
    Marker Score: 53,623
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.55
    Marker Score: 2,427
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.42
    Marker Score: 768
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.37
    Marker Score: 993
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.34
    Marker Score: 2,692
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.32
    Marker Score: 893
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.29
    Marker Score: 8,870
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 2.28
    Marker Score: 1,718
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 2.19
    Marker Score: 1,273
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.05
    Marker Score: 125,807
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.99
    Marker Score: 8,104
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.96
    Marker Score: 20,225
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.94
    Marker Score: 18,266
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.92
    Marker Score: 18,221
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.91
    Marker Score: 70,386
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.88
    Marker Score: 16,137
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.84
    Marker Score: 503
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.81
    Marker Score: 7,493
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.8
    Marker Score: 1,558
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.8
    Marker Score: 1,439
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 1.75
    Marker Score: 23,334
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.75
    Marker Score: 764
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 1.71
    Marker Score: 690
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.63
    Marker Score: 486
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.63
    Marker Score: 5,342
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.57
    Marker Score: 2,419
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.53
    Marker Score: 397
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168,409
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.44
    Marker Score: 3,402
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.43
    Marker Score: 2,909
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.36
    Marker Score: 21,356
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.36
    Marker Score: 551
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.34
    Marker Score: 340
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.27
    Marker Score: 468
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.21
    Marker Score: 1,077
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.2
    Marker Score: 1,458
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.19
    Marker Score: 1,477
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.18
    Marker Score: 1,587
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.18
    Marker Score: 378
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.16
    Marker Score: 39,291
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.16
    Marker Score: 697
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.07
    Marker Score: 677
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.06
    Marker Score: 360
  • Cell Name: bipolar neuron (CL0000103)
    Fold Change: 1.06
    Marker Score: 355
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.04
    Marker Score: 544
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.03
    Marker Score: 789
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.02
    Marker Score: 2,408
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 1.02
    Marker Score: 1,733
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 1.01
    Marker Score: 4,229
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.01
    Marker Score: 1,091
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.01
    Marker Score: 1,260
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 1.01
    Marker Score: 1,421
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 1
    Marker Score: 479
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,798
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,024
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.99
    Marker Score: 320
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,406
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 503
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.97
    Marker Score: 570
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 457
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.96
    Marker Score: 391
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,412
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 0.95
    Marker Score: 2,176
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.95
    Marker Score: 565
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 0.94
    Marker Score: 4,345
  • Cell Name: fat cell (CL0000136)
    Fold Change: 0.93
    Marker Score: 520
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.92
    Marker Score: 453
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,735
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.9
    Marker Score: 2,162
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.9
    Marker Score: 1,121
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 323
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.9
    Marker Score: 5,116
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,296
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.87
    Marker Score: 14,026
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.87
    Marker Score: 603
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.86
    Marker Score: 610
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.83
    Marker Score: 313
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.82
    Marker Score: 2,344
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.81
    Marker Score: 325

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The CACNB2 gene is a member of the calcium voltage-gated channel auxiliary subunit family, which consists of six subunits (β1-β4 and α1). The β2 subunit is specifically expressed in various cell types, including cortical neurons, sympathetic neurons, and cardiac myocytes. The CACNB2 gene has a single coding exon and a short intron, resulting in a 170-amino acid protein with a characteristic β-barrel structure. The β2 subunit interacts with the α1 subunit to form functional L-type calcium channels, which have a high affinity for calcium ions and a rapid activation time. **Pathways and Functions:** The CACNB2 gene is involved in various cellular pathways, including: 1. **Cardiac Conduction:** The β2 subunit is expressed in cardiac myocytes and plays a crucial role in regulating cardiac conduction, particularly in the atrial and ventricular repolarization phases. 2. **Neurotransmission:** The β2 subunit is expressed in sympathetic neurons and is involved in regulating neurotransmitter release, particularly in the regulation of presynaptic cytosolic calcium ion concentration. 3. **Muscle Contraction:** The β2 subunit is expressed in skeletal and cardiac muscle cells and plays a crucial role in regulating muscle contraction, particularly in the regulation of calcium ion transport. 4. **Metabolism:** The β2 subunit is involved in regulating energy metabolism, particularly in the regulation of insulin secretion and glucose uptake in pancreatic β cells. **Clinical Significance:** Dysregulation of the CACNB2 gene has been implicated in various clinical conditions, including: 1. **Cardiovascular Disease:** Mutations in the CACNB2 gene have been associated with arrhythmias, cardiac conduction disorders, and hypertension. 2. **Neurological Disorders:** The β2 subunit has been implicated in regulating neurotransmitter release and synaptic plasticity, and mutations in the CACNB2 gene have been associated with neurological disorders such as Parkinson's disease and Alzheimer's disease. 3. **Metabolic Disorders:** The β2 subunit plays a crucial role in regulating insulin secretion and glucose uptake, and mutations in the CACNB2 gene have been associated with metabolic disorders such as type 2 diabetes and obesity. In conclusion, the CACNB2 gene plays a critical role in regulating calcium ion transport and cellular function, and its dysregulation has been implicated in various clinical conditions. Further research is needed to fully understand the mechanisms underlying the CACNB2 gene's role in human disease and to develop therapeutic strategies for the treatment of related disorders.

Genular Protein ID: 4114303328

Symbol: CACB2_HUMAN

Name: Voltage-dependent L-type calcium channel subunit beta-2

UniProtKB Accession Codes:

Q08289 A6PVM5 A6PVM7 A6PVM8 O00304 Q5QJ99 Q5QJA0 Q5VVG9 Q5VVH0 Q5VWV6 Q6TME1 Q6TME2 Q6TME3 Q8WX81 Q96NZ3 Q96NZ4 Q96NZ5 Q9BWU2 Q9HD32 Q9Y340 Q9Y341

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 8 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 34 EMBL 30 EPD 1 Ensembl 8 ExpressionAtlas 1 GO 20 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 9 RNAct 1 Reactome 7 RefSeq 10 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8494331

Title: Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen.

PubMed ID: 8494331

DOI: 10.1002/ana.410330126

PubMed ID: 9254841

Title: Assignment of human genes for beta 2 and beta 4 subunits of voltage-dependent Ca2+ channels to chromosomes 10p12 and 2q22-q23.

PubMed ID: 9254841

DOI: 10.1007/pl00008704

PubMed ID: 12042350

Title: Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells.

PubMed ID: 12042350

DOI: 10.1113/jphysiol.2002.018515

PubMed ID: 14762176

Title: Molecular heterogeneity of calcium channel beta-subunits in canine and human heart: evidence for differential subcellular localization.

PubMed ID: 14762176

DOI: 10.1152/physiolgenomics.00207.2003

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17525370

Title: Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart.

PubMed ID: 17525370

DOI: 10.1161/circresaha.106.146399

PubMed ID: 22419821

Title: Identification of IGPR-1 as a novel adhesion molecule involved in angiogenesis.

PubMed ID: 22419821

DOI: 10.1091/mbc.e11-11-0934

PubMed ID: 28130356

Title: Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.

PubMed ID: 28130356

DOI: 10.1523/jneurosci.2068-16.2017

PubMed ID: 36424916

Title: Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response.

PubMed ID: 36424916

DOI: 10.1038/s44161-022-00157-y

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 17224476

Title: Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death.

PubMed ID: 17224476

DOI: 10.1161/circulationaha.106.668392

Sequence Information:

  • Length: 660
  • Mass: 73581
  • Checksum: 4A08B141EE66404E
  • Sequence:
    • MVQRDMSKSP PTAAAAVAQE IQMELLENVA PAGALGAAAQ SYGKGARRKN RFKGSDGSTS 
SDTTSNSFVR QGSADSYTSR PSDSDVSLEE DREAVRREAE RQAQAQLEKA KTKPVAFAVR 
TNVSYSAAHE DDVPVPGMAI SFEAKDFLHV KEKFNNDWWI GRLVKEGCEI GFIPSPVKLE 
NMRLQHEQRA KQGKFYSSKS GGNSSSSLGD IVPSSRKSTP PSSAIDIDAT GLDAEENDIP 
ANHRSPKPSA NSVTSPHSKE KRMPFFKKTE HTPPYDVVPS MRPVVLVGPS LKGYEVTDMM 
QKALFDFLKH RFEGRISITR VTADISLAKR SVLNNPSKHA IIERSNTRSS LAEVQSEIER 
IFELARTLQL VVLDADTINH PAQLSKTSLA PIIVYVKISS PKVLQRLIKS RGKSQAKHLN 
VQMVAADKLA QCPPELFDVI LDENQLEDAC EHLADYLEAY WKATHPPSSS LPNPLLSRTL 
ATSSLPLSPT LASNSQGSQG DQRTDRSAPI RSASQAEEEP SVEPVKKSQH RSSSSAPHHN 
HRSGTSRGLS RQETFDSETQ ESRDSAYVEP KEDYSHDHVD HYASHRDHNH RDETHGSSDH 
RHRESRHRSR DVDREQDHNE CNKQRSRHKS KDRYCEKDGE VISKKRNEAG EWNRDVYIRQ

Genular Protein ID: 3999467436

Symbol: Q59H42_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59H42

Database IDs:

ARBA 15 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 616
  • Mass: 69360
  • Checksum: 372E8F373F7015FB
  • Sequence:
    • SHTLTAFCPL FMQCCGLVHR RRVRVSYGSA DSYTSRPSDS DVSLEEDREA VRREAERQAQ 
AQLEKAKTKP VAFAVRTNVS YSAAHEDDVP VPGMAISFEA KDFLHVKEKF NNDWWIGRLV 
KEGCEIGFIP SPVKLENMRL QHEQRAKQGK FYSSKSGGNS SSSLGDIVPS SRKSTPPSSA 
IDIDATGLDA EENDIPANHR SPKPSANSVT SPHSKEKRMP FFKKTEHTPP YDVVPSMRPV 
VLVGPSLKGY EVTDMMQKAL FDFLKHRFEG RISITRVTAD ISLAKRSVLN NPSKHAIIER 
SNTRSSLAEV QSEIERIFEL ARTLQLVVLD ADTINHPAQL SKTSLAPIIV YVKISSPKVL 
QRLIKSRGKS QAKHLNVQMV AADKLAQCPP ELFDVILDEN QLEDACEHLA DYLEAYWKAT 
HPPSSSLPNP LLSRTLATSS LPLSPTLASN SQGSQGDQRT DRSAPIRSAS QAEEEPSVEP 
VKKSQHRSSS SAPHHNHRSG TSRGLSRQET FDSETQESRD SAYVEPKEDY SHDHVDHYAS 
HRDHNHRDET HGSSDHRHRE SRHRSRDVDR EQDHNECNKQ RSRHKSKDRY CEKDGEVISK 
KRNEAGEWNR DVYIRQ

Genular Protein ID: 3254471522

Symbol: Q5VVH1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5VVH1

Database IDs:

ARBA 15 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 ExpressionAtlas 1 GO 3 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 8 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 2 PROSITE-ProRule 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Sequence Information:

  • Length: 612
  • Mass: 68838
  • Checksum: 1D60077179676927
  • Sequence:
    • MKATWIRLLK RAKGGRLKNS DICGSADSYT SRPSDSDVSL EEDREAVRRE AERQAQAQLE 
KAKTKPVAFA VRTNVSYSAA HEDDVPVPGM AISFEAKDFL HVKEKFNNDW WIGRLVKEGC 
EIGFIPSPVK LENMRLQHEQ RAKQGKFYSS KSGGNSSSSL GDIVPSSRKS TPPSSAIDID 
ATGLDAEEND IPANHRSPKP SANSVTSPHS KEKRMPFFKK TEHTPPYDVV PSMRPVVLVG 
PSLKGYEVTD MMQKALFDFL KHRFEGRISI TRVTADISLA KRSVLNNPSK HAIIERSNTR 
SSLAEVQSEI ERIFELARTL QLVVLDADTI NHPAQLSKTS LAPIIVYVKI SSPKVLQRLI 
KSRGKSQAKH LNVQMVAADK LAQCPPELFD VILDENQLED ACEHLADYLE AYWKATHPPS 
SSLPNPLLSR TLATSSLPLS PTLASNSQGS QGDQRTDRSA PIRSASQAEE EPSVEPVKKS 
QHRSSSSAPH HNHRSGTSRG LSRQETFDSE TQESRDSAYV EPKEDYSHDH VDHYASHRDH 
NHRDETHGSS DHRHRESRHR SRDVDREQDH NECNKQRSRH KSKDRYCEKD GEVISKKRNE 
AGEWNRDVYI RQ

Genular Protein ID: 3242227102

Symbol: A0A494C184_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A494C184

Database IDs:

ARBA 15 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 8 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

Sequence Information:

  • Length: 600
  • Mass: 67541
  • Checksum: 142AB87921F82275
  • Sequence:
    • MYYDDDEPSE VGSADSYTSR PSDSDVSLEE DREAVRREAE RQAQAQLEKA KTKPVAFAVR 
TNVSYSAAHE DDVPVPGMAI SFEAKDFLHV KEKFNNDWWI GRLVKEGCEI GFIPSPVKLE 
NMRLQHEQRA KQGKFYSSKS GGNSSSSLGD IVPSSRKSTP PSSAIDIDAT GLDAEENDIP 
ANHRSPKPSA NSVTSPHSKE KRMPFFKKTE HTPPYDVVPS MRPVVLVGPS LKGYEVTDMM 
QKALFDFLKH RFEGRISITR VTADISLAKR SVLNNPSKHA IIERSNTRSS LAEVQSEIER 
IFELARTLQL VVLDADTINH PAQLSKTSLA PIIVYVKISS PKVLQRLIKS RGKSQAKHLN 
VQMVAADKLA QCPPELFDVI LDENQLEDAC EHLADYLEAY WKATHPPSSS LPNPLLSRTL 
ATSSLPLSPT LASNSQGSQG DQRTDRSAPI RSASQAEEEP SVEPVKKSQH RSSSSAPHHN 
HRSGTSRGLS RQETFDSETQ ESRDSAYVEP KEDYSHDHVD HYASHRDHNH RDETHGSSDH 
RHRESRHRSR DVDREQDHNE CNKQRSRHKS KDRYCEKDGE VISKKRNEAG EWNRDVYIRQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.