Details for: CACNB4
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: Purkinje cell (CL0000121)
Fold Change: 4.55
Marker Score: 153,514 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.8
Marker Score: 55,772 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.77
Marker Score: 3,138 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.68
Marker Score: 40,084 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.65
Marker Score: 20,318 - Cell Name: stellate neuron (CL0000122)
Fold Change: 2.57
Marker Score: 13,820 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.56
Marker Score: 10,605 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.45
Marker Score: 90,325 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.33
Marker Score: 88,469 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.29
Marker Score: 8,850 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.26
Marker Score: 661 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.26
Marker Score: 10,437 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.19
Marker Score: 20,603 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 2.11
Marker Score: 1,827 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.07
Marker Score: 127,482 - Cell Name: macroglial cell (CL0000126)
Fold Change: 2.03
Marker Score: 4,663 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 2.02
Marker Score: 20,829 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.92
Marker Score: 18,261 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.88
Marker Score: 16,128 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.83
Marker Score: 1,627 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.72
Marker Score: 36,712 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.68
Marker Score: 704 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.65
Marker Score: 2,547 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.65
Marker Score: 3,354 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.59
Marker Score: 435 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 1.53
Marker Score: 553 - Cell Name: granule cell (CL0000120)
Fold Change: 1.5
Marker Score: 11,334 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 1.49
Marker Score: 863 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,682 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.47
Marker Score: 565 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.39
Marker Score: 448 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 1.37
Marker Score: 4,595 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.36
Marker Score: 464 - Cell Name: renal principal cell (CL0005009)
Fold Change: 1.3
Marker Score: 1,004 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.26
Marker Score: 850 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 1.25
Marker Score: 6,538 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.24
Marker Score: 903 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.19
Marker Score: 377 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.18
Marker Score: 1,254 - Cell Name: neuron (CL0000540)
Fold Change: 1.18
Marker Score: 4,786 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.12
Marker Score: 351 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.1
Marker Score: 17,199 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 1.08
Marker Score: 4,516 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.07
Marker Score: 2,174 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.06
Marker Score: 597 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 1.05
Marker Score: 504 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.02
Marker Score: 4,244 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,808 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,033 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1
Marker Score: 2,350 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,407 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 505 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.97
Marker Score: 403 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 459 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.96
Marker Score: 1,100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,412 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.94
Marker Score: 15,163 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.93
Marker Score: 371 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.92
Marker Score: 5,263 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,737 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 323 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 0.89
Marker Score: 620 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.89
Marker Score: 584 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,283 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.85
Marker Score: 513 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.84
Marker Score: 640 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.83
Marker Score: 1,034 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.82
Marker Score: 4,920 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.82
Marker Score: 1,998 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.81
Marker Score: 3,386 - Cell Name: germ cell (CL0000586)
Fold Change: 0.8
Marker Score: 1,399 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.79
Marker Score: 1,324 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.77
Marker Score: 1,258 - Cell Name: brush cell (CL0002204)
Fold Change: 0.77
Marker Score: 705 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 393 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.76
Marker Score: 915 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 0.74
Marker Score: 696 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.73
Marker Score: 437 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.72
Marker Score: 1,022 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.71
Marker Score: 752 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.71
Marker Score: 560 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.69
Marker Score: 342 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 177 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 0.69
Marker Score: 4,089 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 0.69
Marker Score: 1,838 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 0.67
Marker Score: 1,100 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 0.65
Marker Score: 197 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.64
Marker Score: 150 - Cell Name: starburst amacrine cell (CL0004232)
Fold Change: 0.61
Marker Score: 173 - Cell Name: basal cell (CL0000646)
Fold Change: 0.61
Marker Score: 781 - Cell Name: glial cell (CL0000125)
Fold Change: 0.6
Marker Score: 664 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.6
Marker Score: 6,104 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.6
Marker Score: 3,896 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.59
Marker Score: 380 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 0.58
Marker Score: 2,873 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.58
Marker Score: 339 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.58
Marker Score: 289 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.58
Marker Score: 277 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.57
Marker Score: 144 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 444
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2578729010
Symbol: CACB4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9254841
Title: Assignment of human genes for beta 2 and beta 4 subunits of voltage-dependent Ca2+ channels to chromosomes 10p12 and 2q22-q23.
PubMed ID: 9254841
DOI: 10.1007/pl00008704
PubMed ID: 11880487
Title: Alternative splicing of the beta 4 subunit has alpha 1 subunit subtype-specific effects on Ca2+ channel gating.
PubMed ID: 11880487
PubMed ID: 17618603
Title: The GK domain of the voltage-dependent calcium channel beta subunit is essential for binding to the alpha subunit.
PubMed ID: 17618603
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9628818
Title: Calcium channel beta4 (CACNB4): human ortholog of the mouse epilepsy gene lethargic.
PubMed ID: 9628818
PubMed ID: 10762541
Title: Coding and noncoding variation of the human calcium-channel beta4-subunit gene CACNB4 in patients with idiopathic generalized epilepsy and episodic ataxia.
PubMed ID: 10762541
DOI: 10.1086/302909
PubMed ID: 19807924
Title: Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.
PubMed ID: 19807924
PubMed ID: 16385006
Title: Solution structure of the N-terminal A domain of the human voltage-gated Ca2+channel beta4a subunit.
PubMed ID: 16385006
DOI: 10.1110/ps.051894506
Sequence Information:
- Length: 520
- Mass: 58169
- Checksum: 21025FA9782347FA
- Sequence:
MSSSSYAKNG TADGPHSPTS QVARGTTTRR SRLKRSDGST TSTSFILRQG SADSYTSRPS DSDVSLEEDR EAIRQEREQQ AAIQLERAKS KPVAFAVKTN VSYCGALDED VPVPSTAISF DAKDFLHIKE KYNNDWWIGR LVKEGCEIGF IPSPLRLENI RIQQEQKRGR FHGGKSSGNS SSSLGEMVSG TFRATPTSTA KQKQKVTEHI PPYDVVPSMR PVVLVGPSLK GYEVTDMMQK ALFDFLKHRF DGRISITRVT ADISLAKRSV LNNPSKRAII ERSNTRSSLA EVQSEIERIF ELARSLQLVV LDADTINHPA QLIKTSLAPI IVHVKVSSPK VLQRLIKSRG KSQSKHLNVQ LVAADKLAQC PPEMFDVILD ENQLEDACEH LGEYLEAYWR ATHTTSSTPM TPLLGRNLGS TALSPYPTAI SGLQSQRMRH SNHSTENSPI ERRSLMTSDE NYHNERARKS RNRLSSSSQH SRDHYPLVEE DYPDSYQDTY KPHRNRGSPG GYSHDSRHRL
Genular Protein ID: 2128110640
Symbol: H0Y476_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 473
- Mass: 53158
- Checksum: 513AC44BC0F54D47
- Sequence:
MAGSADSYTS RPSDSDVSLE EDREAIRQER EQQAAIQLER AKSKPVAFAV KTNVSYCGAL DEDVPVPSTA ISFDAKDFLH IKEKYNNDWW IGRLVKEGCE IGFIPSPLRL ENIRIQQEQK RGRFHGGKSS GNSSSSLGEM VSGTFRATPT STAKQKQKVT EHIPPYDVVP SMRPVVLVGP SLKGYEVTDM MQKALFDFLK HRFDGRISIT RVTADISLAK RSVLNNPSKR AIIERSNTRS SLAEVQSEIE RIFELARSLQ LVVLDADTIN HPAQLIKTSL APIIVHVKVS SPKVLQRLIK SRGKSQSKHL NVQLVAADKL AQCPPEMFDV ILDENQLEDA CEHLGEYLEA YWRATHTTSS TPMTPLLGRN LGSTALSPYP TAISGLQSQR MRHSNHSTEN SPIERRSLMT SDENYHNERA RKSRNRLSSS SQHSRDHYPL VEEDYPDSYQ DTYKPHRNRG SPGGYSHDSR HRL
Genular Protein ID: 1767056634
Symbol: A0A1B0GTX8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 410
- Mass: 45682
- Checksum: F7B82AA3E835A341
- Sequence:
MAGSADSYTS RPSDSDVSLE EDREAIRQER EQQAAIQLER AKSKPVAFAV KTNVSYCGAL DEDVPVPSTA ISFDAKDFLH IKEKYNNDWW IGRLVKEGCE IGFIPSPLRL ENIRIQQEQK RGRFHGGKSS GNSSSSLGEM VSGTFRATPT STDGAHSSLR CCTVNASGGV SGAVTERLRA EVQSEIERIF ELARSLQLVV LDADTINHPA QLIKTSLAPI IVHVKVSSPK VLQRLIKSRG KSQSKHLNVQ LVAADKLAQC PPEMFDVILD ENQLEDACEH LGEYLEAYWR ATHTTSSTPM TPLLGRNLGS TALSPYPTAI SGLQSQRMRH SNHSTENSPI ERRSLMTSDE NYHNERARKS RNRLSSSSQH SRDHYPLVEE DYPDSYQDTY KPHRNRGSPG GYSHDSRHRL
Genular Protein ID: 3950973060
Symbol: A0A1B0GTP5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 334
- Mass: 37715
- Checksum: 8848F25194F1E6A1
- Sequence:
MVSGTFRATP TSTAKQKQKV TEHIPPYDVV PSMRPVVLVG PSLKGYEVTD MMQKALFDFL KHRFDGRISI TRVTADISLA KRSVLNNPSK RAIIERSNTR SSLAEVQSEI ERIFELARSL QLVVLDADTI NHPAQLIKTS LAPIIVHVKV SSPKVLQRLI KSRGKSQSKH LNVQLVAADK LAQCPPEMFD VILDENQLED ACEHLGEYLE AYWRATHTTS STPMTPLLGR NLGSTALSPY PTAISGLQSQ RMRHSNHSTE NSPIERRSLM TSDENYHNER ARKSRNRLSS SSQHSRDHYP LVEEDYPDSY QDTYKPHRNR GSPGGYSHDS RHRL
Genular Protein ID: 2289328978
Symbol: A0A1B0GTK1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 423
- Mass: 47231
- Checksum: EACA7B7461C78AFE
- Sequence:
MYDNLYLHGI EDSEAGSADS YTSRPSDSDV SLEEDREAIR QEREQQAAIQ LERAKSKPVA FAVKTNVSYC GALDEDVPVP STAISFDAKD FLHIKEKYNN DWWIGRLVKE GCEIGFIPSP LRLENIRIQQ EQKRGRFHGG KSSGNSSSSL GEMVSGTFRA TPTSTDGAHS SLRCCTVNAS GGVSGAVTER LRAEVQSEIE RIFELARSLQ LVVLDADTIN HPAQLIKTSL APIIVHVKVS SPKVLQRLIK SRGKSQSKHL NVQLVAADKL AQCPPEMFDV ILDENQLEDA CEHLGEYLEA YWRATHTTSS TPMTPLLGRN LGSTALSPYP TAISGLQSQR MRHSNHSTEN SPIERRSLMT SDENYHNERA RKSRNRLSSS SQHSRDHYPL VEEDYPDSYQ DTYKPHRNRG SPGGYSHDSR HRL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.