Details for: CACNB4
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 241.9232
Cell Significance Index: -37.6300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 148.0819
Cell Significance Index: -37.5600 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 78.6144
Cell Significance Index: -32.3900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 15.1706
Cell Significance Index: 4365.0300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 8.7728
Cell Significance Index: -19.2000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 6.1629
Cell Significance Index: 272.6000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 5.6612
Cell Significance Index: 214.3800 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 5.5026
Cell Significance Index: 68.2500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 5.4098
Cell Significance Index: 118.4600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 4.5337
Cell Significance Index: 126.7000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 3.9012
Cell Significance Index: 1399.2900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 3.4030
Cell Significance Index: 46.4300 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 3.1640
Cell Significance Index: 75.8800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 3.1535
Cell Significance Index: 193.8300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 3.1375
Cell Significance Index: 629.3700 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 2.5359
Cell Significance Index: 22.5100 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.0159
Cell Significance Index: 8.6400 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 0.9341
Cell Significance Index: 12.4600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.5530
Cell Significance Index: 351.2400 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.4800
Cell Significance Index: 10.2600 - Cell Name: chandelier cell (CL4023083)
Fold Change: 0.4545
Cell Significance Index: 3.6700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.4161
Cell Significance Index: 11.3300 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.3346
Cell Significance Index: 3.6500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3117
Cell Significance Index: 59.3100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.2798
Cell Significance Index: 14.6900 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.1855
Cell Significance Index: 3.6200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1729
Cell Significance Index: 156.0800 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.1573
Cell Significance Index: 3.1100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.1038
Cell Significance Index: 3.4000 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 0.0984
Cell Significance Index: 1.0300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0634
Cell Significance Index: 4.2600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0317
Cell Significance Index: 3.1400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0290
Cell Significance Index: 54.6300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0289
Cell Significance Index: 5.7400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0009
Cell Significance Index: -0.1700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0035
Cell Significance Index: -2.5800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0086
Cell Significance Index: -1.2500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0089
Cell Significance Index: -1.0900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0090
Cell Significance Index: -16.6900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0097
Cell Significance Index: -1.5800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0109
Cell Significance Index: -16.7600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0131
Cell Significance Index: -17.8400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0184
Cell Significance Index: -1.1300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0216
Cell Significance Index: -0.7600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0295
Cell Significance Index: -13.3900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0316
Cell Significance Index: -0.9100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0319
Cell Significance Index: -24.1500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0486
Cell Significance Index: -35.9700 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0527
Cell Significance Index: -28.7800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0571
Cell Significance Index: -1.8200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0608
Cell Significance Index: -37.9500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0649
Cell Significance Index: -36.5800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0667
Cell Significance Index: -29.4800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1117
Cell Significance Index: -2.3700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1251
Cell Significance Index: -5.6700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.1252
Cell Significance Index: -3.1300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1340
Cell Significance Index: -10.2900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1376
Cell Significance Index: -23.4900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1379
Cell Significance Index: -1.9800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1383
Cell Significance Index: -2.3700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.1478
Cell Significance Index: -16.0800 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.1619
Cell Significance Index: -2.1000 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1676
Cell Significance Index: -3.3700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1769
Cell Significance Index: -37.2500 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.2023
Cell Significance Index: -25.9300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2105
Cell Significance Index: -24.5300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.2220
Cell Significance Index: -30.4900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2303
Cell Significance Index: -23.5300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2482
Cell Significance Index: -32.0700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2619
Cell Significance Index: -19.5200 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: -0.2768
Cell Significance Index: -2.7700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2790
Cell Significance Index: -32.9000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.2830
Cell Significance Index: -19.5700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2907
Cell Significance Index: -33.3000 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.2937
Cell Significance Index: -3.2400 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.2939
Cell Significance Index: -3.7100 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.3283
Cell Significance Index: -8.1900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3470
Cell Significance Index: -36.1300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.3669
Cell Significance Index: -10.4700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.3859
Cell Significance Index: -23.1700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3914
Cell Significance Index: -31.0000 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.4077
Cell Significance Index: -7.0500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.4165
Cell Significance Index: -23.3700 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.4290
Cell Significance Index: -5.3500 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.4291
Cell Significance Index: -9.2700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.4305
Cell Significance Index: -27.1300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.4588
Cell Significance Index: -29.6000 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.4650
Cell Significance Index: -9.7100 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.5084
Cell Significance Index: -6.0800 - Cell Name: neuron (CL0000540)
Fold Change: -0.5106
Cell Significance Index: -4.8400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.5214
Cell Significance Index: -27.1600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.5286
Cell Significance Index: -27.4600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.5287
Cell Significance Index: -24.6500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.5381
Cell Significance Index: -38.0600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.5400
Cell Significance Index: -25.3800 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.5436
Cell Significance Index: -6.8600 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.5711
Cell Significance Index: -9.0600 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.5727
Cell Significance Index: -11.8800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.5863
Cell Significance Index: -20.5400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5982
Cell Significance Index: -19.1600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2578729010
Symbol: CACB4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9254841
Title: Assignment of human genes for beta 2 and beta 4 subunits of voltage-dependent Ca2+ channels to chromosomes 10p12 and 2q22-q23.
PubMed ID: 9254841
DOI: 10.1007/pl00008704
PubMed ID: 11880487
Title: Alternative splicing of the beta 4 subunit has alpha 1 subunit subtype-specific effects on Ca2+ channel gating.
PubMed ID: 11880487
PubMed ID: 17618603
Title: The GK domain of the voltage-dependent calcium channel beta subunit is essential for binding to the alpha subunit.
PubMed ID: 17618603
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9628818
Title: Calcium channel beta4 (CACNB4): human ortholog of the mouse epilepsy gene lethargic.
PubMed ID: 9628818
PubMed ID: 10762541
Title: Coding and noncoding variation of the human calcium-channel beta4-subunit gene CACNB4 in patients with idiopathic generalized epilepsy and episodic ataxia.
PubMed ID: 10762541
DOI: 10.1086/302909
PubMed ID: 19807924
Title: Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.
PubMed ID: 19807924
PubMed ID: 16385006
Title: Solution structure of the N-terminal A domain of the human voltage-gated Ca2+channel beta4a subunit.
PubMed ID: 16385006
DOI: 10.1110/ps.051894506
Sequence Information:
- Length: 520
- Mass: 58169
- Checksum: 21025FA9782347FA
- Sequence:
MSSSSYAKNG TADGPHSPTS QVARGTTTRR SRLKRSDGST TSTSFILRQG SADSYTSRPS DSDVSLEEDR EAIRQEREQQ AAIQLERAKS KPVAFAVKTN VSYCGALDED VPVPSTAISF DAKDFLHIKE KYNNDWWIGR LVKEGCEIGF IPSPLRLENI RIQQEQKRGR FHGGKSSGNS SSSLGEMVSG TFRATPTSTA KQKQKVTEHI PPYDVVPSMR PVVLVGPSLK GYEVTDMMQK ALFDFLKHRF DGRISITRVT ADISLAKRSV LNNPSKRAII ERSNTRSSLA EVQSEIERIF ELARSLQLVV LDADTINHPA QLIKTSLAPI IVHVKVSSPK VLQRLIKSRG KSQSKHLNVQ LVAADKLAQC PPEMFDVILD ENQLEDACEH LGEYLEAYWR ATHTTSSTPM TPLLGRNLGS TALSPYPTAI SGLQSQRMRH SNHSTENSPI ERRSLMTSDE NYHNERARKS RNRLSSSSQH SRDHYPLVEE DYPDSYQDTY KPHRNRGSPG GYSHDSRHRL
Genular Protein ID: 1767056634
Symbol: A0A1B0GTX8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 410
- Mass: 45682
- Checksum: F7B82AA3E835A341
- Sequence:
MAGSADSYTS RPSDSDVSLE EDREAIRQER EQQAAIQLER AKSKPVAFAV KTNVSYCGAL DEDVPVPSTA ISFDAKDFLH IKEKYNNDWW IGRLVKEGCE IGFIPSPLRL ENIRIQQEQK RGRFHGGKSS GNSSSSLGEM VSGTFRATPT STDGAHSSLR CCTVNASGGV SGAVTERLRA EVQSEIERIF ELARSLQLVV LDADTINHPA QLIKTSLAPI IVHVKVSSPK VLQRLIKSRG KSQSKHLNVQ LVAADKLAQC PPEMFDVILD ENQLEDACEH LGEYLEAYWR ATHTTSSTPM TPLLGRNLGS TALSPYPTAI SGLQSQRMRH SNHSTENSPI ERRSLMTSDE NYHNERARKS RNRLSSSSQH SRDHYPLVEE DYPDSYQDTY KPHRNRGSPG GYSHDSRHRL
Genular Protein ID: 3950973060
Symbol: A0A1B0GTP5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 334
- Mass: 37715
- Checksum: 8848F25194F1E6A1
- Sequence:
MVSGTFRATP TSTAKQKQKV TEHIPPYDVV PSMRPVVLVG PSLKGYEVTD MMQKALFDFL KHRFDGRISI TRVTADISLA KRSVLNNPSK RAIIERSNTR SSLAEVQSEI ERIFELARSL QLVVLDADTI NHPAQLIKTS LAPIIVHVKV SSPKVLQRLI KSRGKSQSKH LNVQLVAADK LAQCPPEMFD VILDENQLED ACEHLGEYLE AYWRATHTTS STPMTPLLGR NLGSTALSPY PTAISGLQSQ RMRHSNHSTE NSPIERRSLM TSDENYHNER ARKSRNRLSS SSQHSRDHYP LVEEDYPDSY QDTYKPHRNR GSPGGYSHDS RHRL
Genular Protein ID: 2289328978
Symbol: A0A1B0GTK1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 423
- Mass: 47231
- Checksum: EACA7B7461C78AFE
- Sequence:
MYDNLYLHGI EDSEAGSADS YTSRPSDSDV SLEEDREAIR QEREQQAAIQ LERAKSKPVA FAVKTNVSYC GALDEDVPVP STAISFDAKD FLHIKEKYNN DWWIGRLVKE GCEIGFIPSP LRLENIRIQQ EQKRGRFHGG KSSGNSSSSL GEMVSGTFRA TPTSTDGAHS SLRCCTVNAS GGVSGAVTER LRAEVQSEIE RIFELARSLQ LVVLDADTIN HPAQLIKTSL APIIVHVKVS SPKVLQRLIK SRGKSQSKHL NVQLVAADKL AQCPPEMFDV ILDENQLEDA CEHLGEYLEA YWRATHTTSS TPMTPLLGRN LGSTALSPYP TAISGLQSQR MRHSNHSTEN SPIERRSLMT SDENYHNERA RKSRNRLSSS SQHSRDHYPL VEEDYPDSYQ DTYKPHRNRG SPGGYSHDSR HRL
Genular Protein ID: 2128110640
Symbol: H0Y476_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 473
- Mass: 53158
- Checksum: 513AC44BC0F54D47
- Sequence:
MAGSADSYTS RPSDSDVSLE EDREAIRQER EQQAAIQLER AKSKPVAFAV KTNVSYCGAL DEDVPVPSTA ISFDAKDFLH IKEKYNNDWW IGRLVKEGCE IGFIPSPLRL ENIRIQQEQK RGRFHGGKSS GNSSSSLGEM VSGTFRATPT STAKQKQKVT EHIPPYDVVP SMRPVVLVGP SLKGYEVTDM MQKALFDFLK HRFDGRISIT RVTADISLAK RSVLNNPSKR AIIERSNTRS SLAEVQSEIE RIFELARSLQ LVVLDADTIN HPAQLIKTSL APIIVHVKVS SPKVLQRLIK SRGKSQSKHL NVQLVAADKL AQCPPEMFDV ILDENQLEDA CEHLGEYLEA YWRATHTTSS TPMTPLLGRN LGSTALSPYP TAISGLQSQR MRHSNHSTEN SPIERRSLMT SDENYHNERA RKSRNRLSSS SQHSRDHYPL VEEDYPDSYQ DTYKPHRNRG SPGGYSHDSR HRL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.