Details for: CALCA

Gene ID: 796

Symbol: CALCA

Ensembl ID: ENSG00000110680

Description: calcitonin related polypeptide alpha

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: thymocyte (CL0000893)
    Fold Change: 41.8012
    Cell Significance Index: 528.1700
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 2.4452
    Cell Significance Index: 9.3600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5505
    Cell Significance Index: 300.6200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.5163
    Cell Significance Index: 75.0500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.3425
    Cell Significance Index: 2.7400
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: 0.1868
    Cell Significance Index: 2.4900
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.1448
    Cell Significance Index: 1.7500
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: 0.0659
    Cell Significance Index: 0.8400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0610
    Cell Significance Index: 2.1200
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.0312
    Cell Significance Index: 0.3800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0004
    Cell Significance Index: -0.0200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0015
    Cell Significance Index: -1.0400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0018
    Cell Significance Index: -0.0900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0028
    Cell Significance Index: -5.2900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0033
    Cell Significance Index: -2.1200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0076
    Cell Significance Index: -5.5500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0084
    Cell Significance Index: -15.5500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0095
    Cell Significance Index: -7.0100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0099
    Cell Significance Index: -7.5200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0102
    Cell Significance Index: -4.6300
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0102
    Cell Significance Index: -0.1200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0103
    Cell Significance Index: -15.9100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0116
    Cell Significance Index: -15.7600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0126
    Cell Significance Index: -1.2900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0143
    Cell Significance Index: -8.0800
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0191
    Cell Significance Index: -0.2700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0203
    Cell Significance Index: -5.8400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0217
    Cell Significance Index: -0.3200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0220
    Cell Significance Index: -4.3600
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0226
    Cell Significance Index: -0.3500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0261
    Cell Significance Index: -4.7100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0272
    Cell Significance Index: -5.4600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0368
    Cell Significance Index: -5.0500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0379
    Cell Significance Index: -4.6600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0411
    Cell Significance Index: -0.8600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0467
    Cell Significance Index: -2.0300
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.0492
    Cell Significance Index: -0.5800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0510
    Cell Significance Index: -8.7100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0541
    Cell Significance Index: -6.3100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0561
    Cell Significance Index: -5.8400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0567
    Cell Significance Index: -1.6700
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -0.0586
    Cell Significance Index: -0.5900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0616
    Cell Significance Index: -4.7300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0671
    Cell Significance Index: -14.1400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0719
    Cell Significance Index: -1.0300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0778
    Cell Significance Index: -8.9100
  • Cell Name: contractile cell (CL0000183)
    Fold Change: -0.0872
    Cell Significance Index: -0.1700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0911
    Cell Significance Index: -4.7300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0956
    Cell Significance Index: -6.4300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1017
    Cell Significance Index: -13.1400
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: -0.1065
    Cell Significance Index: -1.1900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1071
    Cell Significance Index: -6.5700
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.1127
    Cell Significance Index: -1.2900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1171
    Cell Significance Index: -6.5700
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1219
    Cell Significance Index: -3.0400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1323
    Cell Significance Index: -6.0000
  • Cell Name: chondroblast (CL0000058)
    Fold Change: -0.1340
    Cell Significance Index: -0.7900
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.1399
    Cell Significance Index: -2.7900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1518
    Cell Significance Index: -6.7200
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.1588
    Cell Significance Index: -1.3500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1619
    Cell Significance Index: -5.6700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1677
    Cell Significance Index: -5.4900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1693
    Cell Significance Index: -12.6200
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: -0.1712
    Cell Significance Index: -1.6300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1721
    Cell Significance Index: -5.4800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1764
    Cell Significance Index: -6.6800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1823
    Cell Significance Index: -3.0700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1836
    Cell Significance Index: -6.7400
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.1846
    Cell Significance Index: -2.3300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1983
    Cell Significance Index: -9.3200
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.2100
    Cell Significance Index: -2.4500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.2165
    Cell Significance Index: -5.4000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2193
    Cell Significance Index: -5.8700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2257
    Cell Significance Index: -6.4400
  • Cell Name: glial cell (CL0000125)
    Fold Change: -0.2291
    Cell Significance Index: -2.5100
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: -0.2293
    Cell Significance Index: -2.1800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2364
    Cell Significance Index: -6.2200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2416
    Cell Significance Index: -5.2900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2458
    Cell Significance Index: -6.6900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2494
    Cell Significance Index: -6.6600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2541
    Cell Significance Index: -5.4900
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.2594
    Cell Significance Index: -6.6100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2601
    Cell Significance Index: -5.5200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2669
    Cell Significance Index: -6.4000
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: -0.2671
    Cell Significance Index: -0.5900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2695
    Cell Significance Index: -5.4100
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.2717
    Cell Significance Index: -5.6700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2779
    Cell Significance Index: -5.5000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.2794
    Cell Significance Index: -5.5000
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: -0.2814
    Cell Significance Index: -2.7100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.2818
    Cell Significance Index: -8.1200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2844
    Cell Significance Index: -4.7600
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.2991
    Cell Significance Index: -3.6100
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.3048
    Cell Significance Index: -2.5600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3151
    Cell Significance Index: -5.4000
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.3168
    Cell Significance Index: -5.2200
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.3175
    Cell Significance Index: -5.3400
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.3238
    Cell Significance Index: -5.5000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.3259
    Cell Significance Index: -5.6400
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: -0.3317
    Cell Significance Index: -3.8400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CALCA is a 37-amino acid peptide hormone that belongs to the CGRP family. It is a key regulator of calcium homeostasis and is involved in the regulation of smooth muscle contraction, neuronal function, and pain modulation. CALCA is highly expressed in the gut, pancreas, and nervous system, and its expression is often upregulated in response to stress, inflammation, or injury. The gene's product is highly conserved across species, suggesting its importance in evolutionarily conserved physiological processes. **Pathways and Functions** CALCA interacts with various receptors and signaling pathways to regulate its physiological effects. The primary pathways involved in CALCA signaling include: 1. **Calcium homeostasis**: CALCA regulates calcium homeostasis by interacting with the calcium-sensing receptor (CaSR) and the parathyroid hormone receptor (PTH1R). This interaction modulates calcium release from intracellular stores and calcium absorption from the gut. 2. **Smooth muscle contraction**: CALCA interacts with the smooth muscle contractile machinery, regulating the contraction of smooth muscle cells. This interaction is mediated by the activation of protein kinase C (PKC) and the subsequent activation of the myosin light chain kinase (MLCK). 3. **Neuronal function**: CALCA interacts with various neuronal receptors, including the CGRP receptor, to regulate neuronal excitability and synaptic transmission. This interaction is mediated by the activation of adenylate cyclase and the subsequent increase in cAMP levels. 4. **Pain modulation**: CALCA is involved in the regulation of pain perception by interacting with the CGRP receptor and the TRPV1 receptor. This interaction modulates the release of pain-related neurotransmitters, such as substance P and calcitonin gene-related peptide (CGRP). **Clinical Significance** CALCA has been implicated in various diseases and disorders, including: 1. **Migraine**: CALCA has been shown to play a key role in the pathophysiology of migraine, a disorder characterized by recurrent episodes of severe headache. 2. **Cardiovascular disease**: CALCA has been implicated in the regulation of blood pressure and cardiovascular function. Elevated CALCA levels have been associated with hypertension and cardiovascular disease. 3. **Pain disorders**: CALCA has been implicated in the regulation of pain perception and has been used as a therapeutic target for pain disorders. 4. **Neurodegenerative disorders**: CALCA has been implicated in the regulation of neuronal function and has been used as a therapeutic target for neurodegenerative disorders, such as Alzheimer's disease. In conclusion, CALCA is a gene that encodes a peptide hormone involved in various physiological processes, including calcium homeostasis, pain modulation, and inflammation. Its expression is widely distributed across various tissues, and its product interacts with various receptors and signaling pathways to regulate its physiological effects. CALCA has been implicated in various diseases and disorders, including migraine, cardiovascular disease, pain disorders, and neurodegenerative disorders, making it a potential therapeutic target for the treatment of these conditions.

Genular Protein ID: 4100537344

Symbol: CALC_HUMAN

Name: Calcitonin

UniProtKB Accession Codes:

P01258 B7ZL39 Q13935 Q13937 Q52LX7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 19 EMDB 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 30 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 2 PRINTS 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 3 RefSeq 4 SMART 1 SMR 1 STRING 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 6546550

Title: The complete sequence of human preprocalcitonin.

PubMed ID: 6546550

DOI: 10.1016/0014-5793(84)80839-x

PubMed ID: 3872459

Title: Alternative RNA processing events in human calcitonin/calcitonin gene-related peptide gene expression.

PubMed ID: 3872459

DOI: 10.1073/pnas.82.7.1994

PubMed ID: 3034287

Title: Expression and function of the human calcitonin/alpha-CGRP gene in health and disease.

PubMed ID: 3034287

PubMed ID: 3485540

Title: Ectopic synthesis of high-Mr calcitonin by the BEN lung carcinoma cell line reflects aberrant proteolytic processing.

PubMed ID: 3485540

DOI: 10.1016/0014-5793(86)81187-5

PubMed ID: 1761559

Title: A novel calcitonin carboxyl-terminal peptide produced in medullary thyroid carcinoma by alternative RNA processing of the calcitonin/calcitonin gene-related peptide gene.

PubMed ID: 1761559

DOI: 10.1016/s0021-9258(18)54275-7

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6148938

Title: Structure and expression of a gene encoding human calcitonin and calcitonin gene related peptide.

PubMed ID: 6148938

DOI: 10.1016/0006-291x(84)90278-x

PubMed ID: 2408883

Title: Expression of the human calcitonin/CGRP gene in lung and thyroid carcinoma.

PubMed ID: 2408883

DOI: 10.1002/j.1460-2075.1985.tb03688.x

PubMed ID: 5760861

Title: Human calcitonin. Structure of calcitonin M and D.

PubMed ID: 5760861

DOI: 10.1002/hlca.19680510811

PubMed ID: 2001366

Title: A 1H NMR study of human calcitonin in solution.

PubMed ID: 2001366

DOI: 10.1021/bi00223a010

PubMed ID: 6132180

Title: Katacalcin: a new plasma calcium-lowering hormone.

PubMed ID: 6132180

DOI: 10.1016/s0140-6736(83)91387-9

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

Sequence Information:

  • Length: 141
  • Mass: 15467
  • Checksum: 99622305DD8B286F
  • Sequence:
    • MGFQKFSPFL ALSILVLLQA GSLHAAPFRS ALESSPADPA TLSEDEARLL LAALVQDYVQ 
MKASELEQEQ EREGSSLDSP RSKRCGNLST CMLGTYTQDF NKFHTFPQTA IGVGAPGKKR 
DMSSDLERDH RPHVSMPQNA N

Genular Protein ID: 2822134813

Symbol: CALCA_HUMAN

Name: Calcitonin gene-related peptide 1

UniProtKB Accession Codes:

P06881 Q93048 Q9UCP0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 5 DrugCentral 1 EMBL 9 EMDB 3 Ensembl 3 ExpressionAtlas 1 GO 29 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 IntAct 1 InterPro 5 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 1 PRINTS 1 PROSITE 1 PathwayCommons 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 Proteomes 1 ProteomicsDB 1 Reactome 2 RefSeq 1 SMART 1 SMR 1 SignaLink 1 TCDB 1 UCSC 1 VEuPathDB 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3872459

Title: Alternative RNA processing events in human calcitonin/calcitonin gene-related peptide gene expression.

PubMed ID: 3872459

DOI: 10.1073/pnas.82.7.1994

PubMed ID: 2571128

Title: Structure and methylation of the human calcitonin/alpha-CGRP gene.

PubMed ID: 2571128

DOI: 10.1093/nar/17.17.6999

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 6148938

Title: Structure and expression of a gene encoding human calcitonin and calcitonin gene related peptide.

PubMed ID: 6148938

DOI: 10.1016/0006-291x(84)90278-x

PubMed ID: 2408883

Title: Expression of the human calcitonin/CGRP gene in lung and thyroid carcinoma.

PubMed ID: 2408883

DOI: 10.1002/j.1460-2075.1985.tb03688.x

PubMed ID: 6610687

Title: Calcitonin gene related peptide coding sequence is conserved in the human genome and is expressed in medullary thyroid carcinoma.

PubMed ID: 6610687

DOI: 10.1210/jcem-59-2-358

PubMed ID: 3034287

Title: Expression and function of the human calcitonin/alpha-CGRP gene in health and disease.

PubMed ID: 3034287

PubMed ID: 6609312

Title: Isolation and characterization of human calcitonin gene-related peptide.

PubMed ID: 6609312

DOI: 10.1038/308746a0

PubMed ID: 3492492

Title: Identification in the human central nervous system, pituitary, and thyroid of a novel calcitonin gene-related peptide, and partial amino acid sequence in the spinal cord.

PubMed ID: 3492492

DOI: 10.1016/s0021-9258(19)75816-5

PubMed ID: 1318039

Title: Isolation and characterization of peptides which act on rat platelets, from a pheochromocytoma.

PubMed ID: 1318039

DOI: 10.1016/s0006-291x(05)80966-0

PubMed ID: 1988044

Title: Solution structure of human calcitonin gene-related peptide by 1H NMR and distance geometry with restrained molecular dynamics.

PubMed ID: 1988044

DOI: 10.1021/bi00216a036

PubMed ID: 2039456

Title: Solution structures of calcitonin-gene-related-peptide analogues of calcitonin-gene-related peptide and amylin.

PubMed ID: 2039456

DOI: 10.1042/bj2750785

Sequence Information:

  • Length: 128
  • Mass: 13899
  • Checksum: A003A1069260D9B8
  • Sequence:
    • MGFQKFSPFL ALSILVLLQA GSLHAAPFRS ALESSPADPA TLSEDEARLL LAALVQDYVQ 
MKASELEQEQ EREGSRIIAQ KRACDTATCV THRLAGLLSR SGGVVKNNFV PTNVGSKAFG 
RRRRDLQA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.