Associated with
Other Information
Genular Protein ID: 1532091721
Symbol: CALM1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 6385987
Title: Isolation and nucleotide sequence of a cDNA encoding human calmodulin.
PubMed ID: 6385987
PubMed ID: 7925473
Title: Structure of the human CALM1 calmodulin gene and identification of two CALM1-related pseudogenes CALM1P1 and CALM1P2.
PubMed ID: 7925473
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7093203
Title: Complete amino acid sequence of human brain calmodulin.
PubMed ID: 7093203
DOI: 10.1021/bi00539a041
PubMed ID: 9804419
Title: Structural basis for activation of the titin kinase domain during myofibrillogenesis.
PubMed ID: 9804419
DOI: 10.1038/27603
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 12871148
Title: Recombinant expression, purification and characterisation of the HMG domain of human SRY.
PubMed ID: 12871148
PubMed ID: 16127172
Title: Calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease TRE17/USP6.
PubMed ID: 16127172
PubMed ID: 15746192
Title: Defective calmodulin-mediated nuclear transport of the sex-determining region of the Y chromosome (SRY) in XY sex reversal.
PubMed ID: 15746192
DOI: 10.1210/me.2004-0334
PubMed ID: 15592455
Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
PubMed ID: 15592455
DOI: 10.1038/nbt1046
PubMed ID: 16760425
Title: CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.
PubMed ID: 16760425
PubMed ID: 17719545
Title: Cep97 and CP110 suppress a cilia assembly program.
PubMed ID: 17719545
PubMed ID: 18165683
Title: The KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction.
PubMed ID: 18165683
PubMed ID: 18650434
Title: S100A1 and calmodulin compete for the same binding site on ryanodine receptor.
PubMed ID: 18650434
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20466722
Title: Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex.
PubMed ID: 20466722
PubMed ID: 20086014
Title: Calcium-dependent association of calmodulin with the rubella virus nonstructural protease domain.
PubMed ID: 20086014
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23109337
Title: Crystal structure of calmodulin binding domain of orai1 in complex with Ca2+ calmodulin displays a unique binding mode.
PubMed ID: 23109337
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22484487
Title: Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning.
PubMed ID: 22484487
DOI: 10.1038/ncb2473
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28890335
Title: The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.
PubMed ID: 28890335
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 30021165
Title: Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca2+/CaM Controls DCV Binding and Liprin-alpha/TANC2 Recruits DCVs to Postsynaptic Sites.
PubMed ID: 30021165
PubMed ID: 30287853
Title: Calcineurin B homologous protein 3 binds with high affinity to the CHP binding domain of the human sodium/proton exchanger NHE1.
PubMed ID: 30287853
PubMed ID: 31155282
Title: Gain-of-function mutations in KCNN3 encoding the small-conductance Ca2+-activated K+ channel SK3 cause Zimmermann-Laband syndrome.
PubMed ID: 31155282
PubMed ID: 31330532
Title: Inhibition of bacterial ubiquitin ligases by SidJ-calmodulin catalysed glutamylation.
PubMed ID: 31330532
PubMed ID: 33667636
Title: Calmodulin binds to the STAS domain of SLC26A5 prestin with a calcium-dependent, one-lobe, binding mode.
PubMed ID: 33667636
PubMed ID: 35338844
Title: Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases.
PubMed ID: 35338844
PubMed ID: 35446120
Title: Calmodulin binding activates chromobacterium CopC effector to ADP-riboxanate host apoptotic caspases.
PubMed ID: 35446120
PubMed ID: 35568036
Title: A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling.
PubMed ID: 35568036
PubMed ID: 9927666
Title: Alpha-helix nucleation by a calcium-binding peptide loop.
PubMed ID: 9927666
PubMed ID: 11685248
Title: Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains.
PubMed ID: 11685248
DOI: 10.1038/nsb1101-990
PubMed ID: 1474585
Title: Calmodulin structure refined at 1.7 A resolution.
PubMed ID: 1474585
PubMed ID: 7803388
Title: Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex.
PubMed ID: 7803388
DOI: 10.1021/bi00255a006
PubMed ID: 11807546
Title: Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
PubMed ID: 11807546
DOI: 10.1038/415396a
PubMed ID: 12485993
Title: Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins.
PubMed ID: 12485993
DOI: 10.1093/emboj/cdf681
PubMed ID: 12577052
Title: Crystal structure of a MARCKS peptide containing the calmodulin-binding domain in complex with Ca2+-calmodulin.
PubMed ID: 12577052
DOI: 10.1038/nsb900
PubMed ID: 16299511
Title: Insights into voltage-gated calcium channel regulation from the structure of the CaV1.2 IQ domain-Ca2+/calmodulin complex.
PubMed ID: 16299511
DOI: 10.1038/nsmb1027
PubMed ID: 15719022
Title: Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
PubMed ID: 15719022
PubMed ID: 21167176
Title: Solution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5.
PubMed ID: 21167176
PubMed ID: 23893133
Title: Allosteric mechanism of water-channel gating by Ca(2+)-calmodulin.
PubMed ID: 23893133
DOI: 10.1038/nsmb.2630
PubMed ID: 25441029
Title: Structural basis of a Kv7.1 potassium channel gating module: studies of the intracellular c-terminal domain in complex with calmodulin.
PubMed ID: 25441029
PubMed ID: 27564677
Title: Structural insights into the M-channel proximal C-terminus/calmodulin complex.
PubMed ID: 27564677
PubMed ID: 27876793
Title: PEP-19 modulates calcium binding to calmodulin by electrostatic steering.
PubMed ID: 27876793
DOI: 10.1038/ncomms13583
PubMed ID: 23607618
Title: NMR structure of calmodulin complexed to an N-terminally acetylated alpha-synuclein peptide.
PubMed ID: 23607618
DOI: 10.1021/bi400199p
PubMed ID: 36423631
Title: Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin.
PubMed ID: 36423631
PubMed ID: 23040497
Title: Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death.
PubMed ID: 23040497
PubMed ID: 23388215
Title: Calmodulin mutations associated with recurrent cardiac arrest in infants.
PubMed ID: 23388215
PubMed ID: 25036739
Title: Altered RyR2 regulation by the calmodulin F90L mutation associated with idiopathic ventricular fibrillation and early sudden cardiac death.
PubMed ID: 25036739
PubMed ID: 24076290
Title: A mutation in CALM1 encoding calmodulin in familial idiopathic ventricular fibrillation in childhood and adolescence.
PubMed ID: 24076290
PubMed ID: 26164367
Title: Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease.
PubMed ID: 26164367
PubMed ID: 27516456
Title: Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks.
PubMed ID: 27516456
PubMed ID: 26969752
Title: Spectrum and Prevalence of CALM1-, CALM2-, and CALM3-Encoded Calmodulin Variants in Long QT Syndrome and Functional Characterization of a Novel Long QT Syndrome-Associated Calmodulin Missense Variant, E141G.
PubMed ID: 26969752
PubMed ID: 27165696
Title: Arrhythmogenic calmodulin mutations impede activation of small-conductance calcium-activated potassium current.
PubMed ID: 27165696
PubMed ID: 28158429
Title: Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes.
PubMed ID: 28158429
DOI: 10.1093/cvr/cvx006
PubMed ID: 31454269
Sequence Information:
- Length: 149
- Mass: 16838
- Checksum: 6B4BC3FCDE10727B
- Sequence:
MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.