Details for: CALM2

Gene ID: 805

Symbol: CALM2

Ensembl ID: ENSG00000143933

Description: calmodulin 2

Associated with

  • Adenylate cyclase activator activity
    (GO:0010856)
  • Adenylate cyclase binding
    (GO:0008179)
  • Calcium-dependent protein binding
    (GO:0048306)
  • Calcium channel complex
    (GO:0034704)
  • Calcium channel inhibitor activity
    (GO:0019855)
  • Calcium ion binding
    (GO:0005509)
  • Catalytic complex
    (GO:1902494)
  • Centrosome
    (GO:0005813)
  • Cytoplasm
    (GO:0005737)
  • Detection of calcium ion
    (GO:0005513)
  • G2/m transition of mitotic cell cycle
    (GO:0000086)
  • G protein-coupled receptor signaling pathway
    (GO:0007186)
  • Membrane
    (GO:0016020)
  • Myelin sheath
    (GO:0043209)
  • Negative regulation of calcium ion export across plasma membrane
    (GO:1905913)
  • Negative regulation of calcium ion transmembrane transporter activity
    (GO:1901020)
  • Negative regulation of peptidyl-threonine phosphorylation
    (GO:0010801)
  • Negative regulation of ryanodine-sensitive calcium-release channel activity
    (GO:0060315)
  • Nucleus
    (GO:0005634)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of cyclic-nucleotide phosphodiesterase activity
    (GO:0051343)
  • Positive regulation of peptidyl-threonine phosphorylation
    (GO:0010800)
  • Positive regulation of phosphoprotein phosphatase activity
    (GO:0032516)
  • Positive regulation of protein autophosphorylation
    (GO:0031954)
  • Positive regulation of protein dephosphorylation
    (GO:0035307)
  • Positive regulation of protein serine/threonine kinase activity
    (GO:0071902)
  • Positive regulation of ryanodine-sensitive calcium-release channel activity
    (GO:0060316)
  • Protein-containing complex
    (GO:0032991)
  • Protein binding
    (GO:0005515)
  • Protein kinase binding
    (GO:0019901)
  • Protein phosphatase activator activity
    (GO:0072542)
  • Protein serine/threonine kinase activator activity
    (GO:0043539)
  • Regulation of calcium-mediated signaling
    (GO:0050848)
  • Regulation of cardiac muscle contraction
    (GO:0055117)
  • Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
    (GO:0010881)
  • Regulation of cell communication by electrical coupling involved in cardiac conduction
    (GO:1901844)
  • Regulation of cytokinesis
    (GO:0032465)
  • Regulation of heart rate
    (GO:0002027)
  • Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
    (GO:0010880)
  • Regulation of ryanodine-sensitive calcium-release channel activity
    (GO:0060314)
  • Response to calcium ion
    (GO:0051592)
  • Sarcomere
    (GO:0030017)
  • Sperm midpiece
    (GO:0097225)
  • Spindle microtubule
    (GO:0005876)
  • Spindle pole
    (GO:0000922)
  • Substantia nigra development
    (GO:0021762)
  • Titin binding
    (GO:0031432)
  • Transmembrane transporter binding
    (GO:0044325)
  • Vesicle
    (GO:0031982)
  • Voltage-gated potassium channel complex
    (GO:0008076)

Other Information

Genular Protein ID: 4035469967

Symbol: Q96HY3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96HY3 A0A9K3Y7M0 D6W5B3 E7ETZ0 H0Y7A7

Database IDs:

ARBA 5 Antibodypedia 3 Bgee 1 BioGRID-ORCS 3 CDD 1 CTD 2 ChiTaRS 2 DNASU 1 EMBL 11 EPD 1 Ensembl 17 GO 3 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 3 HOGENOM 2 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 2 PharmGKB 1 Proteomes 2 ProteomicsDB 2 RefSeq 7 SMART 1 SUPFAM 1 UCSC 3 VEuPathDB 3

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.M111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 113
  • Mass: 12876
  • Checksum: B8CDD96451018E44
  • Sequence:
    • MRSLGQNPTE AELQDMINEV DADGNGTIDF PEFLTMMARK MKDTDSEEEI REAFRVFDKD 
GNGYISAAEL RHVMTNLGEK LTDEEVDEMI READIDGDGQ VNYEEFVQMM TAK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.