Associated with
Other Information
Genular Protein ID: 3509270520
Symbol: CALR_HUMAN
Name: CRP55
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2332496
Title: Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen.
PubMed ID: 2332496
DOI: 10.1172/jci114582
PubMed ID: 1919005
Title: Characterization of the autoantigen calreticulin.
PubMed ID: 1919005
PubMed ID: 1733953
Title: The 5'-flanking region of the human calreticulin gene shares homology with the human GRP78, GRP94, and protein disulfide isomerase promoters.
PubMed ID: 1733953
PubMed ID: 19054851
Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.
PubMed ID: 19054851
DOI: 10.1038/nmeth.1273
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7841019
Title: Human placental calreticulin: purification, characterization and association with other proteins.
PubMed ID: 7841019
PubMed ID: 3260607
Title: Molecular characterization of human Ro/SS-A antigen. Amino terminal sequence of the protein moiety of human Ro/SS-A antigen and immunological activity of a corresponding synthetic peptide.
PubMed ID: 3260607
DOI: 10.1172/jci113607
PubMed ID: 1911778
Title: In vitro interaction of a polypeptide homologous to human Ro/SS-A antigen (calreticulin) with a highly conserved amino acid sequence in the cytoplasmic domain of integrin alpha subunits.
PubMed ID: 1911778
DOI: 10.1021/bi00105a008
PubMed ID: 2400400
Title: Sequence similarity of calreticulin with a Ca2(+)-binding protein that co-purifies with an Ins(1,4,5)P3-sensitive Ca2+ store in HL-60 cells.
PubMed ID: 2400400
DOI: 10.1042/bj2700545
PubMed ID: 1286669
Title: Human liver protein map: a reference database established by microsequencing and gel comparison.
PubMed ID: 1286669
PubMed ID: 1286667
Title: Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.
PubMed ID: 1286667
PubMed ID: 8418194
Title: The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes.
PubMed ID: 8418194
DOI: 10.1084/jem.177.1.1
PubMed ID: 9150948
Title: A two-dimensional gel database of human colon carcinoma proteins.
PubMed ID: 9150948
PubMed ID: 7876246
Title: Calreticulin functions as a molecular chaperone in the biosynthesis of myeloperoxidase.
PubMed ID: 7876246
PubMed ID: 8666824
Title: Calreticulin binds hYRNA and the 52-kDa polypeptide component of the Ro/SS-A ribonucleoprotein autoantigen.
PubMed ID: 8666824
PubMed ID: 9427624
Title: TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide.
PubMed ID: 9427624
PubMed ID: 9640257
Title: Calreticulin associates with non-HLA-A,-B class I proteins in the human choriocarcinoma cell lines JEG-3 and BeWo.
PubMed ID: 9640257
PubMed ID: 10358038
Title: Calreticulin is expressed on the cell surface of activated human peripheral blood T lymphocytes in association with major histocompatibility complex class I molecules.
PubMed ID: 10358038
PubMed ID: 10605026
Title: HLA-F is a predominantly empty, intracellular, TAP-associated MHC class Ib protein with a restricted expression pattern.
PubMed ID: 10605026
PubMed ID: 11149926
Title: Calreticulin is a receptor for nuclear export.
PubMed ID: 11149926
PubMed ID: 11322874
Title: Human placental calreticulin characterization of domain structure and post-translational modifications.
PubMed ID: 11322874
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20801878
Title: Structural basis of cyclophilin B binding by the calnexin/calreticulin P-domain.
PubMed ID: 20801878
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22905912
Title: Resveratrol-induced changes of the human adipocyte secretion profile.
PubMed ID: 22905912
DOI: 10.1021/pr300539b
PubMed ID: 23614004
Title: Structure of the non-catalytic domain of the protein disulfide isomerase-related protein (PDIR) reveals function in protein binding.
PubMed ID: 23614004
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 29192674
Title: Landscape of the regulatory elements for lysine 2-hydroxyisobutyrylation pathway.
PubMed ID: 29192674
DOI: 10.1038/cr.2017.149
PubMed ID: 30157172
Title: Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa.
PubMed ID: 30157172
PubMed ID: 24325356
Title: Somatic mutations of calreticulin in myeloproliferative neoplasms.
PubMed ID: 24325356
PubMed ID: 24325359
Title: Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.
PubMed ID: 24325359
PubMed ID: 19154346
Title: Structural framework of the GABARAP-calreticulin interface -- implications for substrate binding to endoplasmic reticulum chaperones.
PubMed ID: 19154346
PubMed ID: 21423620
Title: X-ray structure of the human calreticulin globular domain reveals a peptide-binding area and suggests a multi-molecular mechanism.
PubMed ID: 21423620
PubMed ID: 27840680
Title: Structures of parasite calreticulins provide insights into their flexibility and dual carbohydrate/peptide-binding properties.
PubMed ID: 27840680
Sequence Information:
- Length: 417
- Mass: 48142
- Checksum: BC37C3C0F1054FB2
- Sequence:
MLLSVPLLLG LLGLAVAEPA VYFKEQFLDG DGWTSRWIES KHKSDFGKFV LSSGKFYGDE EKDKGLQTSQ DARFYALSAS FEPFSNKGQT LVVQFTVKHE QNIDCGGGYV KLFPNSLDQT DMHGDSEYNI MFGPDICGPG TKKVHVIFNY KGKNVLINKD IRCKDDEFTH LYTLIVRPDN TYEVKIDNSQ VESGSLEDDW DFLPPKKIKD PDASKPEDWD ERAKIDDPTD SKPEDWDKPE HIPDPDAKKP EDWDEEMDGE WEPPVIQNPE YKGEWKPRQI DNPDYKGTWI HPEIDNPEYS PDPSIYAYDN FGVLGLDLWQ VKSGTIFDNF LITNDEAYAE EFGNETWGVT KAAEKQMKDK QDEEQRLKEE EEDKKRKEEE EAEDKEDDED KDEDEEDEED KEEDEEEDVP GQAKDEL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.