Details for: CAMK4

Gene ID: 814

Symbol: CAMK4

Ensembl ID: ENSG00000152495

Description: calcium/calmodulin dependent protein kinase IV

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 5.14
    Marker Score: 27,632
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 4.14
    Marker Score: 21,709
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 3.97
    Marker Score: 5,586
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 3.65
    Marker Score: 123,348
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 2.98
    Marker Score: 984
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.68
    Marker Score: 20,537
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 2.66
    Marker Score: 2,128
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.52
    Marker Score: 133,331
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.43
    Marker Score: 92,452
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 2.43
    Marker Score: 2,540
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.41
    Marker Score: 9,998
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.18
    Marker Score: 8,446
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 2.17
    Marker Score: 1,641
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.15
    Marker Score: 20,180
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 2.09
    Marker Score: 8,965
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 2.08
    Marker Score: 5,083
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 2.05
    Marker Score: 4,716
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 2.05
    Marker Score: 1,191
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.04
    Marker Score: 3,430
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.97
    Marker Score: 2,790
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.89
    Marker Score: 17,974
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.88
    Marker Score: 69,436
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.85
    Marker Score: 114,026
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.85
    Marker Score: 926
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.82
    Marker Score: 15,617
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.8
    Marker Score: 8,340
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.8
    Marker Score: 26,843
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.78
    Marker Score: 565
  • Cell Name: granule cell (CL0000120)
    Fold Change: 1.78
    Marker Score: 13,388
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.74
    Marker Score: 728
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 1.74
    Marker Score: 1,272
  • Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
    Fold Change: 1.68
    Marker Score: 369
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.67
    Marker Score: 936
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 1.63
    Marker Score: 495
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 1.62
    Marker Score: 3,171
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 1.59
    Marker Score: 1,789
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.58
    Marker Score: 1,149
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.57
    Marker Score: 6,404
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.54
    Marker Score: 591
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 1.49
    Marker Score: 1,397
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 1.48
    Marker Score: 1,319
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 1.47
    Marker Score: 512
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 1.47
    Marker Score: 2,619
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168,067
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.45
    Marker Score: 14,346
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 1.45
    Marker Score: 6,028
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 1.44
    Marker Score: 888
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.44
    Marker Score: 14,844
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.44
    Marker Score: 4,098
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.39
    Marker Score: 27,593
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 1.38
    Marker Score: 428
  • Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
    Fold Change: 1.32
    Marker Score: 952
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 1.29
    Marker Score: 1,012
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.28
    Marker Score: 350
  • Cell Name: NKp44-positive group 3 innate lymphoid cell, human (CL0001079)
    Fold Change: 1.26
    Marker Score: 284
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.25
    Marker Score: 2,377
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 1.23
    Marker Score: 2,103
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 1.22
    Marker Score: 3,436
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 1.22
    Marker Score: 1,522
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 1.21
    Marker Score: 1,301
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.16
    Marker Score: 694
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.15
    Marker Score: 476
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.14
    Marker Score: 1,413
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.14
    Marker Score: 4,780
  • Cell Name: naive T cell (CL0000898)
    Fold Change: 1.13
    Marker Score: 728
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.1
    Marker Score: 1,332
  • Cell Name: neural cell (CL0002319)
    Fold Change: 1.1
    Marker Score: 530
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 1.09
    Marker Score: 1,027
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.06
    Marker Score: 6,802
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 1.03
    Marker Score: 992
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.02
    Marker Score: 21,839
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1
    Marker Score: 678
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1
    Marker Score: 11,627
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,777
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,004
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.99
    Marker Score: 721
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,404
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: 0.97
    Marker Score: 498
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.96
    Marker Score: 497
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.96
    Marker Score: 452
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,410
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: 0.95
    Marker Score: 2,135
  • Cell Name: motor neuron (CL0000100)
    Fold Change: 0.94
    Marker Score: 556
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 0.93
    Marker Score: 786
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 0.92
    Marker Score: 3,092
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,730
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 0.91
    Marker Score: 800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.91
    Marker Score: 365
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.91
    Marker Score: 416
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.89
    Marker Score: 5,093
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 0.88
    Marker Score: 751
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.88
    Marker Score: 318
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.88
    Marker Score: 763
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,272
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 0.86
    Marker Score: 2,331
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.85
    Marker Score: 1,638
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.84
    Marker Score: 13,163
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.83
    Marker Score: 632
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: 0.81
    Marker Score: 590
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.8
    Marker Score: 8,121

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CAMK4 is a calcium/calmodulin-dependent protein kinase that exhibits a high degree of specificity for calcium/calmodulin binding. This enzyme is characterized by its ability to phosphorylate specific serine or threonine residues on target proteins, which can activate or inhibit various cellular processes. CAMK4 is also known for its involvement in the regulation of neuronal functions, including synaptic plasticity and long-term memory. Additionally, this enzyme plays a role in the adaptive immune response, regulating the production of cytokines and the differentiation of T cells. **Pathways and Functions** CAMK4 is involved in a wide range of signaling pathways, including: 1. **Activation of NMDA receptors and postsynaptic events**: CAMK4 phosphorylates and regulates the activity of NMDA receptors, which are critical for synaptic plasticity and learning. 2. **Adaptive immune response**: CAMK4 regulates the production of cytokines and the differentiation of T cells, which are essential for the adaptive immune response. 3. **ATP binding and Ca-dependent events**: CAMK4 is activated by calcium/calmodulin binding, which triggers a downstream cascade of events involved in various cellular processes. 4. **Protein phosphorylation**: CAMK4 phosphorylates specific serine or threonine residues on target proteins, which can activate or inhibit various cellular processes. 5. **Calmodulin-dependent protein kinase activity**: CAMK4 is a member of the calcium/calmodulin-dependent protein kinase family, which is involved in the regulation of various cellular processes. **Clinical Significance** CAMK4 has been implicated in various diseases and disorders, including: 1. **Disorders of developmental biology**: CAMK4 plays a crucial role in the development of the nervous system and has been implicated in disorders such as Rett syndrome. 2. **Pervasive developmental disorders**: CAMK4 has been linked to pervasive developmental disorders, including autism spectrum disorder. 3. **Neurotransmitter receptors and postsynaptic signal transmission**: CAMK4 regulates the activity of NMDA receptors, which are critical for synaptic plasticity and learning. 4. **Opioid signalling**: CAMK4 has been implicated in the regulation of opioid signalling pathways, which are involved in pain modulation and addiction. 5. **Regulation of mecp2 expression and activity**: CAMK4 regulates the expression and activity of the MECP2 gene, which is critical for the development of the nervous system. In conclusion, CAMK4 is a crucial enzyme involved in various cellular processes, including signal transduction, transcriptional regulation, and protein phosphorylation. Its dysregulation has been implicated in various diseases and disorders, highlighting the importance of this gene in human health and disease.

Genular Protein ID: 3046038767

Symbol: KCC4_HUMAN

Name: Calcium/calmodulin-dependent protein kinase type IV

UniProtKB Accession Codes:

Q16566 D3DSZ7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 12 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 DrugCentral 1 EC 3 EMBL 7 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 20 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 1 PRO 1 PROSITE 3 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 6 RefSeq 3 Rhea 6 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8089075

Title: cDNA cloning and expression of human calmodulin-dependent protein kinase IV.

PubMed ID: 8089075

DOI: 10.1093/oxfordjournals.jbchem.a124387

PubMed ID: 8194751

Title: The cDNA sequence and characterization of the Ca2+/calmodulin-dependent protein kinase-Gr from human brain and thymus.

PubMed ID: 8194751

DOI: 10.1016/0378-1119(94)90260-7

PubMed ID: 8107230

Title: A Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, expressed after transformation of primary human B lymphocytes by Epstein-Barr virus (EBV) is induced by the EBV oncogene LMP1.

PubMed ID: 8107230

DOI: 10.1128/jvi.68.3.1697-1705.1994

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8397199

Title: Expression of a Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, in human T lymphocytes. Regulation of kinase activity by T cell receptor signaling.

PubMed ID: 8397199

DOI: 10.1016/s0021-9258(20)80693-0

PubMed ID: 7961813

Title: Activation mechanisms for Ca2+/calmodulin-dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase.

PubMed ID: 7961813

DOI: 10.1016/s0021-9258(19)61953-8

PubMed ID: 8065343

Title: Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.

PubMed ID: 8065343

DOI: 10.1128/mcb.14.9.6107-6116.1994

PubMed ID: 8980227

Title: CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression.

PubMed ID: 8980227

DOI: 10.1016/s0092-8674(00)81816-4

PubMed ID: 8702940

Title: A unique phosphorylation-dependent mechanism for the activation of Ca2+/calmodulin-dependent protein kinase type IV/GR.

PubMed ID: 8702940

DOI: 10.1074/jbc.271.35.21542

PubMed ID: 8855261

Title: Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade.

PubMed ID: 8855261

DOI: 10.1073/pnas.93.20.10803

PubMed ID: 9154845

Title: Regulation of microtubule dynamics by Ca2+/calmodulin-dependent kinase IV/Gr-dependent phosphorylation of oncoprotein 18.

PubMed ID: 9154845

DOI: 10.1128/mcb.17.6.3459

PubMed ID: 10617605

Title: Ca(2+)-dependent gene expression mediated by MEF2 transcription factors.

PubMed ID: 10617605

DOI: 10.1074/jbc.275.1.197

PubMed ID: 12065094

Title: Ca(2+)/calmodulin-dependent protein kinase IV expression in epithelial ovarian cancer.

PubMed ID: 12065094

DOI: 10.1016/s0304-3835(02)00107-6

PubMed ID: 15143065

Title: Regulation and function of the calcium/calmodulin-dependent protein kinase IV/protein serine/threonine phosphatase 2A signaling complex.

PubMed ID: 15143065

DOI: 10.1074/jbc.m404523200

PubMed ID: 15769749

Title: The autonomous activity of calcium/calmodulin-dependent protein kinase IV is required for its role in transcription.

PubMed ID: 15769749

DOI: 10.1074/jbc.m500067200

PubMed ID: 17909078

Title: Calmodulin-dependent kinase IV links Toll-like receptor 4 signaling with survival pathway of activated dendritic cells.

PubMed ID: 17909078

DOI: 10.1182/blood-2007-05-091173

PubMed ID: 18829949

Title: Upregulation of calcium/calmodulin-dependent protein kinase IV improves memory formation and rescues memory loss with aging.

PubMed ID: 18829949

DOI: 10.1523/jneurosci.2625-08.2008

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19506079

Title: Regulation of calcium/calmodulin-dependent kinase IV by O-GlcNAc modification.

PubMed ID: 19506079

DOI: 10.1074/jbc.m109.007310

PubMed ID: 9920409

Title: Calmodulin-dependent protein kinase IV: regulation of function and expression.

PubMed ID: 9920409

DOI: 10.1016/s0167-4889(98)00142-6

PubMed ID: 18817731

Title: Calmodulin-kinases: modulators of neuronal development and plasticity.

PubMed ID: 18817731

DOI: 10.1016/j.neuron.2008.08.021

PubMed ID: 18930438

Title: Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller.

PubMed ID: 18930438

DOI: 10.1016/j.it.2008.08.005

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 473
  • Mass: 51926
  • Checksum: EFEE51E5612326DC
  • Sequence:
    • MLKVTVPSCS ASSCSSVTAS AAPGTASLVP DYWIDGSNRD ALSDFFEVES ELGRGATSIV 
YRCKQKGTQK PYALKVLKKT VDKKIVRTEI GVLLRLSHPN IIKLKEIFET PTEISLVLEL 
VTGGELFDRI VEKGYYSERD AADAVKQILE AVAYLHENGI VHRDLKPENL LYATPAPDAP 
LKIADFGLSK IVEHQVLMKT VCGTPGYCAP EILRGCAYGP EVDMWSVGII TYILLCGFEP 
FYDERGDQFM FRRILNCEYY FISPWWDEVS LNAKDLVRKL IVLDPKKRLT TFQALQHPWV 
TGKAANFVHM DTAQKKLQEF NARRKLKAAV KAVVASSRLG SASSSHGSIQ ESHKASRDPS 
PIQDGNEDMK AIPEGEKIQG DGAQAAVKGA QAELMKVQAL EKVKGADINA EEAPKMVPKA 
VEDGIKVADL ELEEGLAEEK LKTVEEAAAP REGQGSSAVG FEVPQQDVIL PEY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.