Details for: CAMK4
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: stellate neuron (CL0000122)
Fold Change: 5.14
Marker Score: 27,632 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 4.14
Marker Score: 21,709 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 3.97
Marker Score: 5,586 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 3.65
Marker Score: 123,348 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 2.98
Marker Score: 984 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.68
Marker Score: 20,537 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 2.66
Marker Score: 2,128 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 2.52
Marker Score: 133,331 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.43
Marker Score: 92,452 - Cell Name: thymocyte (CL0000893)
Fold Change: 2.43
Marker Score: 2,540 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.41
Marker Score: 9,998 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.18
Marker Score: 8,446 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 2.17
Marker Score: 1,641 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.15
Marker Score: 20,180 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 2.09
Marker Score: 8,965 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 2.08
Marker Score: 5,083 - Cell Name: macroglial cell (CL0000126)
Fold Change: 2.05
Marker Score: 4,716 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 2.05
Marker Score: 1,191 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.04
Marker Score: 3,430 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1.97
Marker Score: 2,790 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.89
Marker Score: 17,974 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.88
Marker Score: 69,436 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.85
Marker Score: 114,026 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 1.85
Marker Score: 926 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.82
Marker Score: 15,617 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.8
Marker Score: 8,340 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.8
Marker Score: 26,843 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.78
Marker Score: 565 - Cell Name: granule cell (CL0000120)
Fold Change: 1.78
Marker Score: 13,388 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.74
Marker Score: 728 - Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
Fold Change: 1.74
Marker Score: 1,272 - Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
Fold Change: 1.68
Marker Score: 369 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.67
Marker Score: 936 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 1.63
Marker Score: 495 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 1.62
Marker Score: 3,171 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 1.59
Marker Score: 1,789 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.58
Marker Score: 1,149 - Cell Name: neuron (CL0000540)
Fold Change: 1.57
Marker Score: 6,404 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.54
Marker Score: 591 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 1.49
Marker Score: 1,397 - Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 1.48
Marker Score: 1,319 - Cell Name: memory regulatory T cell (CL0002678)
Fold Change: 1.47
Marker Score: 512 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 1.47
Marker Score: 2,619 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,067 - Cell Name: mature T cell (CL0002419)
Fold Change: 1.45
Marker Score: 14,346 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.45
Marker Score: 6,028 - Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
Fold Change: 1.44
Marker Score: 888 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.44
Marker Score: 14,844 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.44
Marker Score: 4,098 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.39
Marker Score: 27,593 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 1.38
Marker Score: 428 - Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
Fold Change: 1.32
Marker Score: 952 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 1.29
Marker Score: 1,012 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.28
Marker Score: 350 - Cell Name: NKp44-positive group 3 innate lymphoid cell, human (CL0001079)
Fold Change: 1.26
Marker Score: 284 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.25
Marker Score: 2,377 - Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
Fold Change: 1.23
Marker Score: 2,103 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 1.22
Marker Score: 3,436 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.22
Marker Score: 1,522 - Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
Fold Change: 1.21
Marker Score: 1,301 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.16
Marker Score: 694 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1.15
Marker Score: 476 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.14
Marker Score: 1,413 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.14
Marker Score: 4,780 - Cell Name: naive T cell (CL0000898)
Fold Change: 1.13
Marker Score: 728 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.1
Marker Score: 1,332 - Cell Name: neural cell (CL0002319)
Fold Change: 1.1
Marker Score: 530 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 1.09
Marker Score: 1,027 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 1.06
Marker Score: 6,802 - Cell Name: double negative T regulatory cell (CL0011024)
Fold Change: 1.03
Marker Score: 992 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.02
Marker Score: 21,839 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1
Marker Score: 678 - Cell Name: blood cell (CL0000081)
Fold Change: 1
Marker Score: 11,627 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,777 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,004 - Cell Name: Unknown (CL0000548)
Fold Change: 0.99
Marker Score: 721 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,404 - Cell Name: natural T-regulatory cell (CL0000903)
Fold Change: 0.97
Marker Score: 498 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.96
Marker Score: 497 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.96
Marker Score: 452 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,410 - Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
Fold Change: 0.95
Marker Score: 2,135 - Cell Name: motor neuron (CL0000100)
Fold Change: 0.94
Marker Score: 556 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 0.93
Marker Score: 786 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 0.92
Marker Score: 3,092 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,730 - Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 0.91
Marker Score: 800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.91
Marker Score: 365 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.91
Marker Score: 416 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.89
Marker Score: 5,093 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 0.88
Marker Score: 751 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.88
Marker Score: 318 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.88
Marker Score: 763 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,272 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.86
Marker Score: 2,331 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.85
Marker Score: 1,638 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.84
Marker Score: 13,163 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.83
Marker Score: 632 - Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
Fold Change: 0.81
Marker Score: 590 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.8
Marker Score: 8,121
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3046038767
Symbol: KCC4_HUMAN
Name: Calcium/calmodulin-dependent protein kinase type IV
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8089075
Title: cDNA cloning and expression of human calmodulin-dependent protein kinase IV.
PubMed ID: 8089075
PubMed ID: 8194751
Title: The cDNA sequence and characterization of the Ca2+/calmodulin-dependent protein kinase-Gr from human brain and thymus.
PubMed ID: 8194751
PubMed ID: 8107230
Title: A Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, expressed after transformation of primary human B lymphocytes by Epstein-Barr virus (EBV) is induced by the EBV oncogene LMP1.
PubMed ID: 8107230
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8397199
Title: Expression of a Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, in human T lymphocytes. Regulation of kinase activity by T cell receptor signaling.
PubMed ID: 8397199
PubMed ID: 7961813
Title: Activation mechanisms for Ca2+/calmodulin-dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase.
PubMed ID: 7961813
PubMed ID: 8065343
Title: Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.
PubMed ID: 8065343
PubMed ID: 8980227
Title: CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression.
PubMed ID: 8980227
PubMed ID: 8702940
Title: A unique phosphorylation-dependent mechanism for the activation of Ca2+/calmodulin-dependent protein kinase type IV/GR.
PubMed ID: 8702940
PubMed ID: 8855261
Title: Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade.
PubMed ID: 8855261
PubMed ID: 9154845
Title: Regulation of microtubule dynamics by Ca2+/calmodulin-dependent kinase IV/Gr-dependent phosphorylation of oncoprotein 18.
PubMed ID: 9154845
PubMed ID: 10617605
Title: Ca(2+)-dependent gene expression mediated by MEF2 transcription factors.
PubMed ID: 10617605
PubMed ID: 12065094
Title: Ca(2+)/calmodulin-dependent protein kinase IV expression in epithelial ovarian cancer.
PubMed ID: 12065094
PubMed ID: 15143065
Title: Regulation and function of the calcium/calmodulin-dependent protein kinase IV/protein serine/threonine phosphatase 2A signaling complex.
PubMed ID: 15143065
PubMed ID: 15769749
Title: The autonomous activity of calcium/calmodulin-dependent protein kinase IV is required for its role in transcription.
PubMed ID: 15769749
PubMed ID: 17909078
Title: Calmodulin-dependent kinase IV links Toll-like receptor 4 signaling with survival pathway of activated dendritic cells.
PubMed ID: 17909078
PubMed ID: 18829949
Title: Upregulation of calcium/calmodulin-dependent protein kinase IV improves memory formation and rescues memory loss with aging.
PubMed ID: 18829949
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19506079
Title: Regulation of calcium/calmodulin-dependent kinase IV by O-GlcNAc modification.
PubMed ID: 19506079
PubMed ID: 9920409
Title: Calmodulin-dependent protein kinase IV: regulation of function and expression.
PubMed ID: 9920409
PubMed ID: 18817731
Title: Calmodulin-kinases: modulators of neuronal development and plasticity.
PubMed ID: 18817731
PubMed ID: 18930438
Title: Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller.
PubMed ID: 18930438
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
Sequence Information:
- Length: 473
- Mass: 51926
- Checksum: EFEE51E5612326DC
- Sequence:
MLKVTVPSCS ASSCSSVTAS AAPGTASLVP DYWIDGSNRD ALSDFFEVES ELGRGATSIV YRCKQKGTQK PYALKVLKKT VDKKIVRTEI GVLLRLSHPN IIKLKEIFET PTEISLVLEL VTGGELFDRI VEKGYYSERD AADAVKQILE AVAYLHENGI VHRDLKPENL LYATPAPDAP LKIADFGLSK IVEHQVLMKT VCGTPGYCAP EILRGCAYGP EVDMWSVGII TYILLCGFEP FYDERGDQFM FRRILNCEYY FISPWWDEVS LNAKDLVRKL IVLDPKKRLT TFQALQHPWV TGKAANFVHM DTAQKKLQEF NARRKLKAAV KAVVASSRLG SASSSHGSIQ ESHKASRDPS PIQDGNEDMK AIPEGEKIQG DGAQAAVKGA QAELMKVQAL EKVKGADINA EEAPKMVPKA VEDGIKVADL ELEEGLAEEK LKTVEEAAAP REGQGSSAVG FEVPQQDVIL PEY
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.