Details for: CAMK2B
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.61
Marker Score: 7,432 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.53
Marker Score: 4,256 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.51
Marker Score: 19,236 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 2.44
Marker Score: 4,962 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.44
Marker Score: 36,479 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.4
Marker Score: 47,725 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.4
Marker Score: 91,034 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.39
Marker Score: 9,891 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.22
Marker Score: 82,018 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.21
Marker Score: 47,246 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 2.2
Marker Score: 1,151 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 2.2
Marker Score: 7,825 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.17
Marker Score: 8,406 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.02
Marker Score: 18,979 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.01
Marker Score: 123,356 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.95
Marker Score: 20,153 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.91
Marker Score: 18,147 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.85
Marker Score: 15,921 - Cell Name: endocrine cell (CL0000163)
Fold Change: 1.77
Marker Score: 914 - Cell Name: neuron (CL0000540)
Fold Change: 1.7
Marker Score: 6,925 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.7
Marker Score: 711 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.67
Marker Score: 2,020 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 1.66
Marker Score: 619 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.66
Marker Score: 3,136 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.65
Marker Score: 1,085 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.64
Marker Score: 2,537 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.64
Marker Score: 55,489 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 1.63
Marker Score: 1,537 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.63
Marker Score: 6,790 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.61
Marker Score: 36,063 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.61
Marker Score: 1,167 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.58
Marker Score: 7,313 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,792 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.34
Marker Score: 20,909 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.32
Marker Score: 362 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.28
Marker Score: 405 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 1.23
Marker Score: 407 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.17
Marker Score: 449 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.15
Marker Score: 4,811 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.14
Marker Score: 1,606 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.13
Marker Score: 715 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.12
Marker Score: 2,276 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 1.09
Marker Score: 501 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.08
Marker Score: 436 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.04
Marker Score: 707 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.04
Marker Score: 793 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,815 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1
Marker Score: 414 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,040 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 507 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,408 - Cell Name: stellate neuron (CL0000122)
Fold Change: 0.97
Marker Score: 5,233 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 460 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.97
Marker Score: 839 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,413 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5,345 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.93
Marker Score: 372 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,739 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 324 - Cell Name: granule cell (CL0000120)
Fold Change: 0.88
Marker Score: 6,663 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,287 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 0.86
Marker Score: 288 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.83
Marker Score: 1,948 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 0.82
Marker Score: 4,311 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.79
Marker Score: 473 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,261 - Cell Name: brush cell (CL0002204)
Fold Change: 0.78
Marker Score: 708 - Cell Name: macroglial cell (CL0000126)
Fold Change: 0.77
Marker Score: 1,772 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.76
Marker Score: 239 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 395 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.75
Marker Score: 564 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.73
Marker Score: 209 - Cell Name: PP cell (CL0000696)
Fold Change: 0.72
Marker Score: 163 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.72
Marker Score: 460 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.71
Marker Score: 183 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 0.7
Marker Score: 361 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 178 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.69
Marker Score: 777 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 0.69
Marker Score: 402 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 0.67
Marker Score: 1,951 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.67
Marker Score: 612 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 0.66
Marker Score: 2,201 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.66
Marker Score: 313 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.65
Marker Score: 6,629 - Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 0.63
Marker Score: 218 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.6
Marker Score: 194 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.56
Marker Score: 148 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 442 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.55
Marker Score: 174 - Cell Name: epithelial cell of thymus (CL0002293)
Fold Change: 0.54
Marker Score: 173 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 0.53
Marker Score: 863 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.5
Marker Score: 486 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.49
Marker Score: 276 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.48
Marker Score: 1,415 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.45
Marker Score: 516 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 0.45
Marker Score: 215 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 0.44
Marker Score: 1,319 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.44
Marker Score: 159 - Cell Name: centrocyte (CL0009111)
Fold Change: 0.43
Marker Score: 102 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.42
Marker Score: 412
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3454572469
Symbol: KCC2B_HUMAN
Name: Calcium/calmodulin-dependent protein kinase type II subunit beta
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10858498
Title: Identification of alternative splicing variants of the beta subunit of human Ca(2+)/calmodulin-dependent protein kinase II with different activities.
PubMed ID: 10858498
PubMed ID: 10819240
Title: Cloning and quantitative determination of the human Ca2+/calmodulin-dependent protein kinase II (CaMK II) isoforms in human beta cells.
PubMed ID: 10819240
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12690205
Title: Human chromosome 7: DNA sequence and biology.
PubMed ID: 12690205
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9060999
Title: Identification of novel human tumor cell-specific CaMK-II variants.
PubMed ID: 9060999
PubMed ID: 14722083
Title: Comparative analyses of the three-dimensional structures and enzymatic properties of alpha, beta, gamma and delta isoforms of Ca2+-calmodulin-dependent protein kinase II.
PubMed ID: 14722083
PubMed ID: 15312654
Title: SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation.
PubMed ID: 15312654
PubMed ID: 16690701
Title: Ca2+-calmodulin-dependent protein kinase expression and signalling in skeletal muscle during exercise.
PubMed ID: 16690701
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 21529938
Title: Analysis of CaM-kinase signaling in cells.
PubMed ID: 21529938
PubMed ID: 15294044
Title: The role of calcium and calcium/calmodulin-dependent kinases in skeletal muscle plasticity and mitochondrial biogenesis.
PubMed ID: 15294044
DOI: 10.1079/pns2004335
PubMed ID: 18817731
Title: Calmodulin-kinases: modulators of neuronal development and plasticity.
PubMed ID: 18817731
PubMed ID: 19996366
Title: The roles of CaMKII and F-actin in the structural plasticity of dendritic spines: a potential molecular identity of a synaptic tag?
PubMed ID: 19996366
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 31930741
Title: FAM134B oligomerization drives endoplasmic reticulum membrane scission for ER-phagy.
PubMed ID: 31930741
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
PubMed ID: 29100089
Title: De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability.
PubMed ID: 29100089
PubMed ID: 29560374
Title: De novo variants in CAMK2A and CAMK2B cause neurodevelopmental disorders.
PubMed ID: 29560374
DOI: 10.1002/acn3.528
Sequence Information:
- Length: 666
- Mass: 72678
- Checksum: 8CACFC3E392C3857
- Sequence:
MATTVTCTRF TDEYQLYEDI GKGAFSVVRR CVKLCTGHEY AAKIINTKKL SARDHQKLER EARICRLLKH SNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI LEAVLHCHQM GVVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY LSPEVLRKEA YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT VTPEAKNLIN QMLTINPAKR ITAHEALKHP WVCQRSTVAS MMHRQETVEC LKKFNARRKL KGAILTTMLA TRNFSVGRQT TAPATMSTAA SGTTMGLVEQ AKSLLNKKAD GVKPQTNSTK NSAAATSPKG TLPPAALEPQ TTVIHNPVDG IKESSDSANT TIEDEDAKAP RVPDILSSVR RGSGAPEAEG PLPCPSPAPF SPLPAPSPRI SDILNSVRRG SGTPEAEGPL SAGPPPCLSP ALLGPLSSPS PRISDILNSV RRGSGTPEAE GPSPVGPPPC PSPTIPGPLP TPSRKQEIIK TTEQLIEAVN NGDFEAYAKI CDPGLTSFEP EALGNLVEGM DFHRFYFENL LAKNSKPIHT TILNPHVHVI GEDAACIAYI RLTQYIDGQG RPRTSQSEET RVWHRRDGKW QNVHFHCSGA PVAPLQ
Genular Protein ID: 2641500323
Symbol: B7Z1Z6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 305
- Mass: 33295
- Checksum: D5587FCFDD28E56E
- Sequence:
MGVVHRDLKP ENLLLASKCK GAAVKLADFG LAIEVQGDQQ AWFGFAGTPG YLSPEVLRKE AYGKPVDIWA CGVILYILLV GYPPFWDEDQ HKLYQQIKAG AYDFPSPEWD TVTPEAKNLI NQMLTINPAK RITAHEALKH PWVCQRSTVA SMMHRQETVE CLKKFNARRK LKGAILTTML ATRNFSVGRQ TTAPATMSTA ASGTTMGLVE QAKSLLNKKA DGVKPQTNST KNSAAATSPK GTLPPAALEP QTTVIHNPVD GIKESSDSAN TTIEDEDAKA RKQEIIKTTE QLIEAVNNGD FEAYA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.