Details for: CAMK2G

Gene ID: 818

Symbol: CAMK2G

Ensembl ID: ENSG00000148660

Description: calcium/calmodulin dependent protein kinase II gamma

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 246.4878
    Cell Significance Index: -38.3400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 128.0538
    Cell Significance Index: -32.4800
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 98.2649
    Cell Significance Index: -40.4800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 82.5527
    Cell Significance Index: -38.9800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 79.4325
    Cell Significance Index: -32.2700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 73.0775
    Cell Significance Index: -37.5900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 34.2082
    Cell Significance Index: -32.6600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 31.4042
    Cell Significance Index: -38.7200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.5431
    Cell Significance Index: -36.2800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 12.0008
    Cell Significance Index: -36.8600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.5913
    Cell Significance Index: -23.1800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.8706
    Cell Significance Index: -38.9500
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 3.8789
    Cell Significance Index: 54.2400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2.5624
    Cell Significance Index: 68.4200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.1350
    Cell Significance Index: 428.2700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.6853
    Cell Significance Index: 20.0900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.5787
    Cell Significance Index: 256.7600
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.3638
    Cell Significance Index: 16.9200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.3450
    Cell Significance Index: 482.4200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.2247
    Cell Significance Index: 16.7100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1266
    Cell Significance Index: 1017.2500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.1235
    Cell Significance Index: 24.3400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.1193
    Cell Significance Index: 130.4400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.0094
    Cell Significance Index: 63.6200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.8543
    Cell Significance Index: 24.6200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8209
    Cell Significance Index: 49.2800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.7741
    Cell Significance Index: 535.3800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7572
    Cell Significance Index: 82.3600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7507
    Cell Significance Index: 148.9800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6999
    Cell Significance Index: 126.1700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.6569
    Cell Significance Index: 16.4200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.6271
    Cell Significance Index: 5.7800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5949
    Cell Significance Index: 30.9100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.5611
    Cell Significance Index: 29.4600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5065
    Cell Significance Index: 22.9600
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.4839
    Cell Significance Index: 3.7300
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.4783
    Cell Significance Index: 6.3800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.4727
    Cell Significance Index: 12.1500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4237
    Cell Significance Index: 11.8400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4124
    Cell Significance Index: 50.7100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3978
    Cell Significance Index: 24.4500
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.3832
    Cell Significance Index: 6.6300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.3134
    Cell Significance Index: 21.0700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.3070
    Cell Significance Index: 139.3200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2617
    Cell Significance Index: 5.7300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.1832
    Cell Significance Index: 3.9200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.1568
    Cell Significance Index: 2.3500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1525
    Cell Significance Index: 7.1100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1432
    Cell Significance Index: 27.2600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1234
    Cell Significance Index: 67.3900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1077
    Cell Significance Index: 47.6300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1051
    Cell Significance Index: 161.8500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0913
    Cell Significance Index: 168.4100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0656
    Cell Significance Index: 4.5400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0564
    Cell Significance Index: 5.5800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0489
    Cell Significance Index: 1.7200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0486
    Cell Significance Index: 66.0800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0327
    Cell Significance Index: 61.6300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0251
    Cell Significance Index: 15.9400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0121
    Cell Significance Index: -8.9300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0336
    Cell Significance Index: -4.6200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0341
    Cell Significance Index: -25.7800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0354
    Cell Significance Index: -25.9400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0368
    Cell Significance Index: -22.9800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0369
    Cell Significance Index: -20.8400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0513
    Cell Significance Index: -8.7600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0600
    Cell Significance Index: -7.0800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0734
    Cell Significance Index: -1.7600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0755
    Cell Significance Index: -5.7900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0843
    Cell Significance Index: -8.7800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0984
    Cell Significance Index: -20.7200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1105
    Cell Significance Index: -14.1600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1196
    Cell Significance Index: -34.4200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1342
    Cell Significance Index: -7.5300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1352
    Cell Significance Index: -13.8100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1414
    Cell Significance Index: -20.5500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1423
    Cell Significance Index: -3.0300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1567
    Cell Significance Index: -10.1100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1633
    Cell Significance Index: -21.1000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1787
    Cell Significance Index: -9.3100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1852
    Cell Significance Index: -5.4400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2091
    Cell Significance Index: -23.8700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2121
    Cell Significance Index: -24.3100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2218
    Cell Significance Index: -4.6000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2338
    Cell Significance Index: -10.9900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2518
    Cell Significance Index: -17.8100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2737
    Cell Significance Index: -4.6900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2941
    Cell Significance Index: -9.4200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.3078
    Cell Significance Index: -7.5100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3484
    Cell Significance Index: -25.9600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3519
    Cell Significance Index: -8.9900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3557
    Cell Significance Index: -7.5500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4170
    Cell Significance Index: -13.2800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4321
    Cell Significance Index: -34.2200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4764
    Cell Significance Index: -16.5600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4829
    Cell Significance Index: -15.8100
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.4876
    Cell Significance Index: -5.3800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5288
    Cell Significance Index: -15.0900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.5414
    Cell Significance Index: -10.7100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.5491
    Cell Significance Index: -24.2900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CAMK2G is a gamma subunit of the CaMKII enzyme, which is composed of four subunits: alpha, beta, gamma, and delta. The gamma subunit is essential for the assembly and cell surface presentation of NMDA receptors, a crucial step in synaptic plasticity and learning. CAMK2G also exhibits calcium- and calmodulin-dependent protein kinase activity, enabling it to phosphorylate and regulate various downstream targets. **Pathways and Functions:** CAMK2G is involved in numerous signaling pathways, including: 1. **Activation of NMDA receptors and postsynaptic events**: CAMK2G plays a critical role in the assembly and cell surface presentation of NMDA receptors, facilitating synaptic plasticity and learning. 2. **Assembly and cell surface presentation of NMDA receptors**: CAMK2G is essential for the correct assembly and presentation of NMDA receptors at the synapse. 3. **Calcium- and calmodulin-dependent protein kinase complex**: CAMK2G is part of the CaMKII complex, which regulates various cellular processes, including neuronal excitability and immune responses. 4. **Cytokine signaling in the immune system**: CAMK2G is involved in the regulation of cytokine signaling pathways, modulating immune responses and inflammation. 5. **Neuronal system development**: CAMK2G plays a role in the development and maturation of neurons, particularly in the regulation of synaptic plasticity and learning. **Clinical Significance:** CAMK2G has significant implications in various diseases and disorders, including: 1. **Neurological disorders**: CAMK2G dysregulation has been implicated in neurological disorders, such as epilepsy, Alzheimer's disease, and Parkinson's disease. 2. **Immune system disorders**: CAMK2G plays a crucial role in regulating immune responses, and dysregulation has been linked to autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. 3. **Cancer**: CAMK2G has been implicated in cancer development and progression, particularly in the regulation of cell growth and survival. 4. **Cardiac conduction disorders**: CAMK2G dysregulation has been linked to cardiac conduction disorders, such as atrioventricular block and long QT syndrome. In conclusion, CAMK2G is a complex enzyme involved in various cellular signaling pathways, with significant implications in neurological, immune, and cancer disorders. Further research is needed to fully understand the mechanisms and clinical implications of CAMK2G dysregulation, ultimately leading to the development of novel therapeutic strategies.

Genular Protein ID: 2658331193

Symbol: KCC2G_HUMAN

Name: Calcium/calmodulin-dependent protein kinase type II subunit gamma

UniProtKB Accession Codes:

Q13555 A0A0A0MS52 A0A0A0MT11 O00561 O15378 Q13279 Q13282 Q13556 Q5SQZ3 Q5SQZ4 Q5SWX4 Q7KYX5 Q8N4I3 Q8NIA4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 6 CDD 1 CTD 1 ChEBI 12 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 DrugCentral 1 EC 3 EMBL 16 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 10 Pumba 1 RNAct 1 Reactome 21 RefSeq 6 Rhea 6 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 3 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9240463

Title: Human islets of Langerhans express multiple isoforms of calcium/calmodulin-dependent protein kinase II.

PubMed ID: 9240463

DOI: 10.1006/bbrc.1997.6871

PubMed ID: 12032636

Title: Human calcium/calmodulin-dependent protein kinase II gamma: cloning, genomic structure and detection of variants in subjects with type II diabetes.

PubMed ID: 12032636

DOI: 10.1007/s00125-002-0779-8

PubMed ID: 8449910

Title: Cloning and analysis of two new isoforms of multifunctional Ca2+/calmodulin-dependent protein kinase. Expression in multiple human tissues.

PubMed ID: 8449910

DOI: 10.1016/s0021-9258(18)53345-7

PubMed ID: 9060999

Title: Identification of novel human tumor cell-specific CaMK-II variants.

PubMed ID: 9060999

DOI: 10.1016/s0167-4889(96)00141-3

PubMed ID: 7557101

Title: Human biliary epithelial cell line Mz-ChA-1 expresses new isoforms of calmodulin-dependent protein kinase II.

PubMed ID: 7557101

DOI: 10.1016/0016-5085(95)90594-4

PubMed ID: 14722083

Title: Comparative analyses of the three-dimensional structures and enzymatic properties of alpha, beta, gamma and delta isoforms of Ca2+-calmodulin-dependent protein kinase II.

PubMed ID: 14722083

DOI: 10.1074/jbc.m313597200

PubMed ID: 16690701

Title: Ca2+-calmodulin-dependent protein kinase expression and signalling in skeletal muscle during exercise.

PubMed ID: 16690701

DOI: 10.1113/jphysiol.2006.111757

PubMed ID: 15294044

Title: The role of calcium and calcium/calmodulin-dependent kinases in skeletal muscle plasticity and mitochondrial biogenesis.

PubMed ID: 15294044

DOI: 10.1079/pns2004335

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 20668654

Title: Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation.

PubMed ID: 20668654

DOI: 10.1371/journal.pbio.1000426

PubMed ID: 23033978

Title: Diagnostic exome sequencing in persons with severe intellectual disability.

PubMed ID: 23033978

DOI: 10.1056/nejmoa1206524

PubMed ID: 30184290

Title: The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function.

PubMed ID: 30184290

DOI: 10.1002/humu.23647

Sequence Information:

  • Length: 558
  • Mass: 62607
  • Checksum: 7D61AB799B8F8CEB
  • Sequence:
    • MATTATCTRF TDDYQLFEEL GKGAFSVVRR CVKKTSTQEY AAKIINTKKL SARDHQKLER 
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIHQI 
LESVNHIHQH DIVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGEQQA WFGFAGTPGY 
LSPEVLRKDP YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT 
VTPEAKNLIN QMLTINPAKR ITADQALKHP WVCQRSTVAS MMHRQETVEC LRKFNARRKL 
KGAILTTMLV SRNFSAAKSL LNKKSDGGVK KRKSSSSVHL MPQSNNKNSL VSPAQEPAPL 
QTAMEPQTTV VHNATDGIKG STESCNTTTE DEDLKGRVPE GRSSRDRTAP SAGMQPQPSL 
CSSAMRKQEI IKITEQLIEA INNGDFEAYT KICDPGLTSF EPEALGNLVE GMDFHKFYFE 
NLLSKNSKPI HTTILNPHVH VIGEDAACIA YIRLTQYIDG QGRPRTSQSE ETRVWHRRDG 
KWLNVHYHCS GAPAAPLQ

Genular Protein ID: 2177474137

Symbol: B3KY86_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KY86

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 10 DNASU 1 DisGeNET 1 EC 2 EMBL 2 GO 4 Gene3D 3 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 2 RefSeq 1 Rhea 6 SAM 1 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 575
  • Mass: 63800
  • Checksum: C16BC4F86D9FA2FE
  • Sequence:
    • MATTATCTRF TDDYQLFEEL GKCVKKTSTQ EYAAKIINTK KLSARDHQKL EREARICRLL 
KHPNIVRLHD SISEEGFHYL VFDLVTGGEL FEDIVAREYY SEADASHCIH QILESVNHIH 
QHDIVHRDLK PENLLLASKC KGAAVKLADF GLAIEVQGEQ QAWFGFAGTP GYLSPEVLRK 
DPYGKPVDIW ACGVILYILL VGYPPFWDED QHKLYQQIKA GAYDFPSPEW DTVTPEAKNL 
INQMLTINPA KRITADQALK HPWVCQRSTV ASMMHRQETV ECLRKFNARR KLKGAILTTM 
LVSRNFSAAK SLLNKKSDGG VKPQSNNKNS LVSPAQEPAP LQTAMEPQTT VVHNATDGIK 
GSTESCNTTT EDEDLKAAPL RTGNGSPVPE GRSSRDRTAP SAGMQPQPSL CSSAMRKQEI 
IKITEQLIEA INNGDFEAYT KICDPGLTSF EPEALGNLVE GMDFHKFYFE NREWVRAADI 
LLPAPLPLCL CLLLTFSSQL PTFPLFDLRA ALLLCMLVPL CPDGCRQAPL KALLLSSKCH 
SFCSCFVAVP VTTIKLTYFL PGAVAYACNP NTLGG

Genular Protein ID: 2450670704

Symbol: A0A2Q3DQE3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2Q3DQE3

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 ChEBI 11 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 2 EMBL 6 Ensembl 2 GO 4 Gene3D 3 GeneTree 1 HGNC 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 6 SAM 1 SMART 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 556
  • Mass: 62165
  • Checksum: B0E88BF9F07715CB
  • Sequence:
    • MATTATCTRF TDDYQLFEEL GKGAFSVVRR CVKKTSTQEY AAKIINTKKL SARDHQKLER 
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIHQI 
LESVNHIHQH DIVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGEQQA WFGFAGTPGY 
LSPEVLRKDP YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT 
VTPEAKNLIN QMLTINPAKR ITADQALKHP WVCQRSTVAS MMHRQETVEC LRKFNARRKL 
KGAILTTMLV SRNFSAAKSL LNKKSDGGVK PQSNNKNSLV SPAQEPAPLQ TAMEPQTTVV 
HNATDGIKGS TESCNTTTED EDLKAAPLRT GNGSSVPEGR SSRDRTAPSA GMQPQPSLCS 
SAMRKQEIIK ITEQLIEAIN NGDFEAYTKI CDPGLTSFEP EALGNLVEGM DFHKFYFENL 
LSKNSKPIHT TILNPHVHVI GEDAACIAYI RLTQYIDGQG RPRTSQSEET RVWHRRDGKW 
LNVHYHCSGA PAAPLQ

Genular Protein ID: 2694242159

Symbol: Q13280_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q13280

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 2 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PIR 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 9240463

Title: Human islets of Langerhans express multiple isoforms of calcium/calmodulin-dependent protein kinase II.

PubMed ID: 9240463

DOI: 10.1006/bbrc.1997.6871

Sequence Information:

  • Length: 281
  • Mass: 30860
  • Checksum: 76DF4F47814A4FED
  • Sequence:
    • STVASMMHRQ ETVECLRKFN ARRKLKGAIL TTMLVSRNFS AAKSLLNKKS DGGVKPQSNN 
KNSLVSPAQE PAPLQTAMEP QTTVVHNATD GIKGSTESCN TTTEDEDLKA APLRTGNGSS 
VPEGRSSRDR TAPSAGMQPQ PSLCSSAMRK QEIIKITEQL IEAINNGDFE AYTKICDPGL 
TSFEPEALGN LVEGMDFHKF YFENLLSKNS KPIHTTILNP HVHVIGEDAA CIAYIRLTQY 
IDGQGRPRTS QSEETRVWHR RDGKWLNVHY HCSGAPAAPL Q

Genular Protein ID: 60959645

Symbol: Q5SWX3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5SWX3

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 11 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 2 EMBL 6 Ensembl 2 GO 4 Gene3D 3 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 6 SMART 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 516
  • Mass: 57797
  • Checksum: 141109E5974467AF
  • Sequence:
    • MATTATCTRF TDDYQLFEEL GKGAFSVVRR CVKKTSTQEY AAKIINTKKL SARDHQKLER 
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIHQI 
LESVNHIHQH DIVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGEQQA WFGFAGTPGY 
LSPEVLRKDP YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT 
VTPEAKNLIN QMLTINPAKR ITADQALKHP WVCQRSTVAS MMHRQETVEC LRKFNARRKL 
KGAILTTMLV SRNFSVGRQS SAPASPAASA AGLAGQAAKS LLNKKSDGGV KEPQTTVVHN 
ATDGIKGSTE SCNTTTEDED LKVRKQEIIK ITEQLIEAIN NGDFEAYTKI CDPGLTSFEP 
EALGNLVEGM DFHKFYFENL LSKNSKPIHT TILNPHVHVI GEDAACIAYI RLTQYIDGQG 
RPRTSQSEET RVWHRRDGKW LNVHYHCSGA PAAPLQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.