Details for: CAMP

Gene ID: 820

Symbol: CAMP

Ensembl ID: ENSG00000164047

Description: cathelicidin antimicrobial peptide

Associated with

Other Information

Genular Protein ID: 544523925

Symbol: CAMP_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7529412

Title: FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis.

PubMed ID: 7529412

DOI: 10.1073/pnas.92.1.195

PubMed ID: 7615076

Title: hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules.

PubMed ID: 7615076

DOI: 10.1016/0014-5793(95)00634-l

PubMed ID: 7890387

Title: Human CAP18: a novel antimicrobial lipopolysaccharide-binding protein.

PubMed ID: 7890387

DOI: 10.1128/iai.63.4.1291-1297.1995

PubMed ID: 8946956

Title: Structural, functional analysis and localization of the human CAP18 gene.

PubMed ID: 8946956

DOI: 10.1016/s0014-5793(96)01199-4

PubMed ID: 8681941

Title: The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes.

PubMed ID: 8681941

DOI: 10.1111/j.1432-1033.1996.0325z.x

PubMed ID: 11238224

Title: Rhesus monkey (Macaca mulatta) mucosal antimicrobial peptides are close homologues of human molecules.

PubMed ID: 11238224

DOI: 10.1128/cdli.8.2.370-375.2001

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9736536

Title: Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils.

PubMed ID: 9736536

DOI: 10.1128/aac.42.9.2206

PubMed ID: 10417311

Title: Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity.

PubMed ID: 10417311

DOI: 10.1042/bj3410501

PubMed ID: 11389039

Title: Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3.

PubMed ID: 11389039

DOI: 10.1182/blood.v97.12.3951

PubMed ID: 14978112

Title: Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense.

PubMed ID: 14978112

DOI: 10.4049/jimmunol.172.5.3070

PubMed ID: 15778390

Title: Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities.

PubMed ID: 15778390

DOI: 10.4049/jimmunol.174.7.4271

PubMed ID: 21463582

Title: Transmembrane pores formed by human antimicrobial peptide LL-37.

PubMed ID: 21463582

DOI: 10.1016/j.bpj.2011.02.018

PubMed ID: 22879591

Title: Cathepsin G-regulated release of formyl peptide receptor agonists modulate neutrophil effector functions.

PubMed ID: 22879591

DOI: 10.1074/jbc.m112.394452

PubMed ID: 34708076

Title: Quorum Sensing Pseudomonas Quinolone Signal Forms Chiral Supramolecular Assemblies With the Host Defense Peptide LL-37.

PubMed ID: 34708076

DOI: 10.3389/fmolb.2021.742023

PubMed ID: 16637646

Title: Solution structures of human LL-37 fragments and NMR-based identification of a minimal membrane-targeting antimicrobial and anticancer region.

PubMed ID: 16637646

DOI: 10.1021/ja0584875

PubMed ID: 18818205

Title: Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles.

PubMed ID: 18818205

DOI: 10.1074/jbc.m805533200

PubMed ID: 22185690

Title: Structure, dynamics, and antimicrobial and immune modulatory activities of human LL-23 and its single-residue variants mutated on the basis of homologous primate cathelicidins.

PubMed ID: 22185690

DOI: 10.1021/bi2016266

PubMed ID: 23406372

Title: Structural and functional analysis of the pro-domain of human cathelicidin, LL-37.

PubMed ID: 23406372

DOI: 10.1021/bi301008r

PubMed ID: 29087182

Title: Conformational Aspects of High Content Packing of Antimicrobial Peptides in Polymer Microgels.

PubMed ID: 29087182

DOI: 10.1021/acsami.7b13714

PubMed ID: 29133814

Title: Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species.

PubMed ID: 29133814

DOI: 10.1038/s41598-017-14206-1

PubMed ID: 29317506

Title: The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.

PubMed ID: 29317506

DOI: 10.1074/jbc.ra117.001013

PubMed ID: 32753597

Title: The Human LL-37(17-29) antimicrobial peptide reveals a functional supramolecular structure.

PubMed ID: 32753597

DOI: 10.1038/s41467-020-17736-x

PubMed ID: 33060695

Title: The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics.

PubMed ID: 33060695

DOI: 10.1038/s41598-020-74401-5

PubMed ID: 35061360

Title: Rare by Natural Selection: Disulfide-Bonded Supramolecular Antimicrobial Peptides.

PubMed ID: 35061360

DOI: 10.1021/acs.biomac.1c01353

Sequence Information:

  • Length: 170
  • Mass: 19301
  • Checksum: 055B07DCA95A7D16
  • Sequence:
  • MKTQRDGHSL GRWSLVLLLL GLVMPLAIIA QVLSYKEAVL RAIDGINQRS SDANLYRLLD 
    LDPRPTMDGD PDTPKPVSFT VKETVCPRTT QQSPEDCDFK KDGLVKRCMG TVTLNQARGS 
    FDISCDKDNK RFALLGDFFR KSKEKIGKEF KRIVQRIKDF LRNLVPRTES

Genular Protein ID: 261572625

Symbol: J3KNB4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 173
  • Mass: 19591
  • Checksum: 5D1D86D6A0038858
  • Sequence:
  • MGTMKTQRDG HSLGRWSLVL LLLGLVMPLA IIAQVLSYKE AVLRAIDGIN QRSSDANLYR 
    LLDLDPRPTM DGDPDTPKPV SFTVKETVCP RTTQQSPEDC DFKKDGLVKR CMGTVTLNQA 
    RGSFDISCDK DNKRFALLGD FFRKSKEKIG KEFKRIVQRI KDFLRNLVPR TES

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.