Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 3.56
Marker Score: 8,105 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 3.49
Marker Score: 2,732 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 3.34
Marker Score: 8,940 - Cell Name: IgG plasmablast (CL0000982)
Fold Change: 3.27
Marker Score: 902 - Cell Name: acinar cell (CL0000622)
Fold Change: 3.15
Marker Score: 2,220 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 3.13
Marker Score: 3,773 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 3.03
Marker Score: 7,631 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 2.93
Marker Score: 12,206 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.89
Marker Score: 51,346 - Cell Name: stromal cell (CL0000499)
Fold Change: 2.87
Marker Score: 3,357 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 2.87
Marker Score: 25,146 - Cell Name: IgA plasmablast (CL0000984)
Fold Change: 2.84
Marker Score: 746 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.8
Marker Score: 96,846 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 2.68
Marker Score: 1,562 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 2.61
Marker Score: 9,261 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.59
Marker Score: 88,248 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 2.58
Marker Score: 2,757 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 2.58
Marker Score: 2,616 - Cell Name: lung macrophage (CL1001603)
Fold Change: 2.51
Marker Score: 2,869 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 2.5
Marker Score: 1,424 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 2.5
Marker Score: 3,533 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 2.49
Marker Score: 2,642 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 2.48
Marker Score: 1,655 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 2.47
Marker Score: 18,408 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 2.44
Marker Score: 4,318 - Cell Name: ciliated cell (CL0000064)
Fold Change: 2.43
Marker Score: 8,367 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 2.43
Marker Score: 15,848 - Cell Name: pneumocyte (CL0000322)
Fold Change: 2.43
Marker Score: 3,899 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 2.42
Marker Score: 12,708 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 2.41
Marker Score: 3,992 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.38
Marker Score: 569 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 2.38
Marker Score: 9,198 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 2.37
Marker Score: 11,659 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 2.35
Marker Score: 1,097 - Cell Name: blood cell (CL0000081)
Fold Change: 2.34
Marker Score: 27,208 - Cell Name: hepatoblast (CL0005026)
Fold Change: 2.34
Marker Score: 7,656 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.34
Marker Score: 26,314 - Cell Name: serous secreting cell (CL0000313)
Fold Change: 2.32
Marker Score: 927 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 2.32
Marker Score: 4,716 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 2.32
Marker Score: 59,384 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 2.31
Marker Score: 2,310 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 2.31
Marker Score: 5,239 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 2.3
Marker Score: 9,607 - Cell Name: endocardial cell (CL0002350)
Fold Change: 2.3
Marker Score: 1,299 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 2.29
Marker Score: 128,245 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 2.26
Marker Score: 19,652 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 2.18
Marker Score: 5,930 - Cell Name: endocrine cell (CL0000163)
Fold Change: 2.18
Marker Score: 1,126 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 2.17
Marker Score: 698 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 2.17
Marker Score: 1,029 - Cell Name: peptic cell (CL0000155)
Fold Change: 2.16
Marker Score: 906 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 2.16
Marker Score: 4,549 - Cell Name: ependymal cell (CL0000065)
Fold Change: 2.15
Marker Score: 749 - Cell Name: lung secretory cell (CL1000272)
Fold Change: 2.15
Marker Score: 1,914 - Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: 2.13
Marker Score: 676 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 2.13
Marker Score: 2,632 - Cell Name: paneth cell (CL0000510)
Fold Change: 2.13
Marker Score: 1,479 - Cell Name: decidual cell (CL2000002)
Fold Change: 2.12
Marker Score: 9,130 - Cell Name: endothelial cell (CL0000115)
Fold Change: 2.11
Marker Score: 1,895 - Cell Name: kidney cell (CL1000497)
Fold Change: 2.11
Marker Score: 1,406 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 2.11
Marker Score: 1,400 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 2.1
Marker Score: 13,685 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 2.1
Marker Score: 1,651 - Cell Name: podocyte (CL0000653)
Fold Change: 2.1
Marker Score: 776 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 2.1
Marker Score: 6,582 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.09
Marker Score: 9,688 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.09
Marker Score: 2,202 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 2.09
Marker Score: 4,176 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.09
Marker Score: 3,071 - Cell Name: secretory cell (CL0000151)
Fold Change: 2.07
Marker Score: 3,783 - Cell Name: erythroblast (CL0000765)
Fold Change: 2.07
Marker Score: 1,292 - Cell Name: plasmablast (CL0000980)
Fold Change: 2.07
Marker Score: 2,749 - Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 2.05
Marker Score: 1,483 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 2.04
Marker Score: 2,157 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 2.04
Marker Score: 5,079 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 2.03
Marker Score: 2,797 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 2.03
Marker Score: 764 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 2.03
Marker Score: 586 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 2.02
Marker Score: 3,943 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.02
Marker Score: 4,216 - Cell Name: Unknown (CL0000548)
Fold Change: 2.01
Marker Score: 1,466 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 2
Marker Score: 4,798 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 2
Marker Score: 1,502 - Cell Name: stem cell (CL0000034)
Fold Change: 2
Marker Score: 4,754 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 2
Marker Score: 2,151 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 2
Marker Score: 745 - Cell Name: hepatocyte (CL0000182)
Fold Change: 2
Marker Score: 1,363 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.99
Marker Score: 20,019 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 1.99
Marker Score: 12,680 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.99
Marker Score: 7,662 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 1.99
Marker Score: 5,198 - Cell Name: epithelial cell (CL0000066)
Fold Change: 1.98
Marker Score: 3,148 - Cell Name: promonocyte (CL0000559)
Fold Change: 1.98
Marker Score: 1,275 - Cell Name: starburst amacrine cell (CL0004232)
Fold Change: 1.98
Marker Score: 561 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.97
Marker Score: 1,808 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 1.97
Marker Score: 16,948 - Cell Name: enterocyte (CL0000584)
Fold Change: 1.97
Marker Score: 9,432 - Cell Name: tracheobronchial serous cell (CL0019001)
Fold Change: 1.97
Marker Score: 718 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 1.96
Marker Score: 2,129 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 1.96
Marker Score: 558
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4218414032
Symbol: CALX_HUMAN
Name: Calnexin
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8486646
Title: Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin).
PubMed ID: 8486646
PubMed ID: 8136357
Title: Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5.
PubMed ID: 8136357
DOI: 10.1021/bi00177a013
PubMed ID: 8055875
Title: The molecular chaperones HSP28, GRP78, endoplasmin, and calnexin exhibit strikingly different levels in quiescent keratinocytes as compared to their proliferating normal and transformed counterparts: cDNA cloning and expression of calnexin.
PubMed ID: 8055875
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1326756
Title: The major histocompatibility complex class I antigen-binding protein p88 is the product of the calnexin gene.
PubMed ID: 1326756
PubMed ID: 1286667
Title: Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.
PubMed ID: 1286667
PubMed ID: 9188622
Title: Formation of intracellular particles by hepatitis B virus large surface protein.
PubMed ID: 9188622
PubMed ID: 9420286
Title: Role for calnexin and N-linked glycosylation in the assembly and secretion of hepatitis B virus middle envelope protein particles.
PubMed ID: 9420286
PubMed ID: 12643545
Title: Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.
PubMed ID: 12643545
DOI: 10.1021/pr025562r
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16361248
Title: Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome.
PubMed ID: 16361248
PubMed ID: 17081065
Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.
PubMed ID: 17081065
DOI: 10.1021/pr060363j
PubMed ID: 18088087
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18318008
Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.
PubMed ID: 18318008
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20801878
Title: Structural basis of cyclophilin B binding by the calnexin/calreticulin P-domain.
PubMed ID: 20801878
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21205830
Title: A systematic search for endoplasmic reticulum (ER) membrane-associated RING finger proteins identifies Nixin/ZNRF4 as a regulator of calnexin stability and ER homeostasis.
PubMed ID: 21205830
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22314232
Title: Palmitoylated calnexin is a key component of the ribosome-translocon complex.
PubMed ID: 22314232
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23826168
Title: SERPINA2 is a novel gene with a divergent function from SERPINA1.
PubMed ID: 23826168
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24196833
Title: Mutations in Fis1 disrupt orderly disposal of defective mitochondria.
PubMed ID: 24196833
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 29765154
Title: The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation.
PubMed ID: 29765154
PubMed ID: 31735293
Title: TMX2 is a crucial regulator of cellular redox state, and its dysfunction causes severe brain developmental abnormalities.
PubMed ID: 31735293
PubMed ID: 32783947
Title: NACHO Engages N-Glycosylation ER Chaperone Pathways for alpha7 Nicotinic Receptor Assembly.
PubMed ID: 32783947
PubMed ID: 34338405
Title: Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control.
PubMed ID: 34338405
Sequence Information:
- Length: 592
- Mass: 67568
- Checksum: EDE094D9B82261EE
- Sequence:
MEGKWLLCML LVLGTAIVEA HDGHDDDVID IEDDLDDVIE EVEDSKPDTT APPSSPKVTY KAPVPTGEVY FADSFDRGTL SGWILSKAKK DDTDDEIAKY DGKWEVEEMK ESKLPGDKGL VLMSRAKHHA ISAKLNKPFL FDTKPLIVQY EVNFQNGIEC GGAYVKLLSK TPELNLDQFH DKTPYTIMFG PDKCGEDYKL HFIFRHKNPK TGIYEEKHAK RPDADLKTYF TDKKTHLYTL ILNPDNSFEI LVDQSVVNSG NLLNDMTPPV NPSREIEDPE DRKPEDWDER PKIPDPEAVK PDDWDEDAPA KIPDEEATKP EGWLDDEPEY VPDPDAEKPE DWDEDMDGEW EAPQIANPRC ESAPGCGVWQ RPVIDNPNYK GKWKPPMIDN PSYQGIWKPR KIPNPDFFED LEPFRMTPFS AIGLELWSMT SDIFFDNFII CADRRIVDDW ANDGWGLKKA ADGAAEPGVV GQMIEAAEER PWLWVVYILT VALPVFLVIL FCCSGKKQTS GMEYKKTDAP QPDVKEEEEE KEEEKDKGDE EEEGEEKLEE KQKSDAEEDG GTVSQEEEDR KPKAEEDEIL NRSPRNRKPR RE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.