Details for: CAPN1

Gene ID: 823

Symbol: CAPN1

Ensembl ID: ENSG00000014216

Description: calpain 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 170.1756
    Cell Significance Index: -26.4700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 118.3157
    Cell Significance Index: -30.0100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 97.1968
    Cell Significance Index: -40.0400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 80.3499
    Cell Significance Index: -37.9400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 79.4325
    Cell Significance Index: -32.2700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 71.9500
    Cell Significance Index: -37.0100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 56.7455
    Cell Significance Index: -38.0800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 34.2920
    Cell Significance Index: -32.7400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 28.1924
    Cell Significance Index: -34.7600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.1353
    Cell Significance Index: -29.8300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.4069
    Cell Significance Index: -37.1200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.2925
    Cell Significance Index: -25.4700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 4.4252
    Cell Significance Index: 40.7500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.6514
    Cell Significance Index: 137.7300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.4865
    Cell Significance Index: 67.6800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.4233
    Cell Significance Index: 436.8500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.4016
    Cell Significance Index: 295.3000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.9255
    Cell Significance Index: 53.8100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.7422
    Cell Significance Index: 46.5200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.6812
    Cell Significance Index: 108.4700
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.6079
    Cell Significance Index: 24.4200
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.3249
    Cell Significance Index: 30.6100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.2279
    Cell Significance Index: 57.2500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.0634
    Cell Significance Index: 580.7400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.0571
    Cell Significance Index: 15.8400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.0560
    Cell Significance Index: 30.4300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.9043
    Cell Significance Index: 399.8200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.8736
    Cell Significance Index: 41.0600
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 0.8600
    Cell Significance Index: 7.3900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.8437
    Cell Significance Index: 38.2400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.8038
    Cell Significance Index: 56.8500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7904
    Cell Significance Index: 128.5500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.6828
    Cell Significance Index: 80.5200
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.6568
    Cell Significance Index: 9.3500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.6464
    Cell Significance Index: 88.7700
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.6441
    Cell Significance Index: 5.4100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.6193
    Cell Significance Index: 46.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6182
    Cell Significance Index: 122.6800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.6101
    Cell Significance Index: 78.8200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.5850
    Cell Significance Index: 30.4700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5383
    Cell Significance Index: 58.5500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4613
    Cell Significance Index: 92.5300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.4352
    Cell Significance Index: 12.7800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3661
    Cell Significance Index: 46.9300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3042
    Cell Significance Index: 274.6900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2839
    Cell Significance Index: 48.4900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.2622
    Cell Significance Index: 6.7400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.2618
    Cell Significance Index: 5.4800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1918
    Cell Significance Index: 18.9700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1356
    Cell Significance Index: 48.6300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1318
    Cell Significance Index: 4.2200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1266
    Cell Significance Index: 4.4500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1239
    Cell Significance Index: 9.5100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1218
    Cell Significance Index: 84.2300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1163
    Cell Significance Index: 22.1300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1047
    Cell Significance Index: 2.2300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0220
    Cell Significance Index: 16.6500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0194
    Cell Significance Index: 36.4700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0097
    Cell Significance Index: 17.8300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0051
    Cell Significance Index: -7.8600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0088
    Cell Significance Index: -6.5300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0144
    Cell Significance Index: -10.5900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0157
    Cell Significance Index: -9.9700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0216
    Cell Significance Index: -9.8000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0236
    Cell Significance Index: -0.4000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0257
    Cell Significance Index: -16.0300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0288
    Cell Significance Index: -39.2200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0334
    Cell Significance Index: -3.4100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0413
    Cell Significance Index: -2.5400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0415
    Cell Significance Index: -23.3900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0469
    Cell Significance Index: -0.4800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0655
    Cell Significance Index: -1.2100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0902
    Cell Significance Index: -1.2300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0951
    Cell Significance Index: -20.0300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1001
    Cell Significance Index: -28.8200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1196
    Cell Significance Index: -2.0500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1294
    Cell Significance Index: -4.5000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1303
    Cell Significance Index: -15.1800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1382
    Cell Significance Index: -15.8300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1484
    Cell Significance Index: -21.5700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1502
    Cell Significance Index: -3.9500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1663
    Cell Significance Index: -8.7300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1965
    Cell Significance Index: -5.0200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2636
    Cell Significance Index: -5.7100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2763
    Cell Significance Index: -31.5400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3084
    Cell Significance Index: -19.4400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3264
    Cell Significance Index: -33.9900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3304
    Cell Significance Index: -8.2600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3785
    Cell Significance Index: -25.4500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3842
    Cell Significance Index: -30.4300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4515
    Cell Significance Index: -27.6800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.4718
    Cell Significance Index: -5.3600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4987
    Cell Significance Index: -13.3400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.5302
    Cell Significance Index: -23.4500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.5777
    Cell Significance Index: -32.4200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5990
    Cell Significance Index: -17.1700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6185
    Cell Significance Index: -23.4200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6505
    Cell Significance Index: -19.1600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.6608
    Cell Significance Index: -8.2400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.7366
    Cell Significance Index: -16.1300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Calcium-dependent activity**: Calpain 1's enzymatic activity is activated by calcium ions, which regulate its proteolytic activity. 2. **Broad tissue expression**: Calpain 1 is expressed in various epithelial tissues, including esophagus, conjunctiva, trachea, placenta, bladder, and urethra. 3. **Involvement in cell signaling**: Calpain 1 regulates various signaling pathways, including those involved in cell proliferation, apoptosis, and immune responses. 4. **Proteolytic activity**: Calpain 1 is a cysteine-type endopeptidase that cleaves specific protein substrates, leading to changes in protein function and cellular behavior. 5. **Self-proteolysis**: Calpain 1 can undergo self-proteolysis, which regulates its activity and prevents excessive proteolytic activity. **Pathways and Functions** 1. **Cell proliferation**: Calpain 1 regulates cell cycle progression and proliferation by cleaving key proteins involved in these processes. 2. **Apoptosis**: Calpain 1 can induce apoptosis by cleaving pro-survival proteins, leading to cell death. 3. **Immune responses**: Calpain 1 regulates immune responses by cleaving proteins involved in inflammation and immune cell activation. 4. **Neurodegenerative diseases**: Calpain 1 has been implicated in neurodegenerative diseases, including Alzheimer's disease, where it regulates NMDA receptor activity and promotes neuronal damage. 5. **Cancer**: Calpain 1 can promote cancer progression by regulating cell proliferation, invasion, and metastasis. **Clinical Significance** 1. **Neurodegenerative diseases**: Calpain 1's role in neurodegenerative diseases makes it a potential therapeutic target for treatments aimed at reducing neuronal damage and promoting recovery. 2. **Cancer**: Calpain 1's involvement in cancer progression highlights its potential as a therapeutic target for cancer treatments. 3. **Autoimmune conditions**: Calpain 1's regulation of immune responses makes it a potential target for treatments aimed at reducing inflammation and promoting immune tolerance. 4. **Cardiovascular diseases**: Calpain 1's role in cardiovascular diseases, including atherosclerosis and cardiac hypertrophy, makes it a potential therapeutic target for treatments aimed at reducing cardiovascular risk. 5. **Wound healing**: Calpain 1's regulation of proteolytic activity and tissue remodeling makes it a potential therapeutic target for treatments aimed at promoting wound healing and tissue repair. In conclusion, Calpain 1 is a multifunctional enzyme that plays a crucial role in various cellular processes, including cell signaling, proliferation, and apoptosis. Its unique ability to regulate protein degradation and signaling pathways makes it a key player in maintaining cellular homeostasis and responding to environmental changes. Understanding Calpain 1's role in various diseases and developing targeted therapies aimed at modulating its activity could lead to the development of novel treatments for a range of diseases.

Genular Protein ID: 3003816363

Symbol: CAN1_HUMAN

Name: N/A

UniProtKB Accession Codes:

P07384 Q2TTR0 Q6DHV4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CORUM 1 CPTAC 2 CTD 1 ChEBI 16 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EC 1 EMBL 6 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 23 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 1 PRIDE 1 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 4 RefSeq 5 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3017764

Title: Complete amino acid sequence of the large subunit of the low-Ca2+-requiring form of human Ca2+-activated neutral protease (muCANP) deduced from its cDNA sequence.

PubMed ID: 3017764

DOI: 10.1016/0014-5793(86)80919-x

PubMed ID: 2400579

Title: A novel member of the calcium-dependent cysteine protease family.

PubMed ID: 2400579

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8954105

Title: Modulation of the calpain autoproteolysis by calpastatin and phospholipids.

PubMed ID: 8954105

DOI: 10.1006/bbrc.1996.1779

PubMed ID: 8769305

Title: Autolysis of human erythrocyte calpain produces two active enzyme forms with different cell localization.

PubMed ID: 8769305

DOI: 10.1016/0014-5793(96)00775-2

PubMed ID: 9271093

Title: Calcium-binding properties of human erythrocyte calpain.

PubMed ID: 9271093

DOI: 10.1042/bj3250721

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19617626

Title: Calpain-1 cleaves and activates caspase-7.

PubMed ID: 19617626

DOI: 10.1074/jbc.m109.038174

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21531719

Title: Deimination of human filaggrin-2 promotes its proteolysis by calpain 1.

PubMed ID: 21531719

DOI: 10.1074/jbc.m110.197400

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23707407

Title: PLEIAD/SIMC1/C5orf25, a novel autolysis regulator for a skeletal-muscle-specific calpain, CAPN3, scaffolds a CAPN3 substrate, CTBP1.

PubMed ID: 23707407

DOI: 10.1016/j.jmb.2013.05.009

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 27153400

Title: Mutations in CAPN1 cause autosomal-recessive hereditary spastic paraplegia.

PubMed ID: 27153400

DOI: 10.1016/j.ajhg.2016.04.002

PubMed ID: 16411745

Title: Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core.

PubMed ID: 16411745

DOI: 10.1021/bi052077b

Sequence Information:

  • Length: 714
  • Mass: 81890
  • Checksum: 1CB6D7C56D063498
  • Sequence:
    • MSEEIITPVY CTGVSAQVQK QRARELGLGR HENAIKYLGQ DYEQLRVRCL QSGTLFRDEA 
FPPVPQSLGY KDLGPNSSKT YGIKWKRPTE LLSNPQFIVD GATRTDICQG ALGDCWLLAA 
IASLTLNDTL LHRVVPHGQS FQNGYAGIFH FQLWQFGEWV DVVVDDLLPI KDGKLVFVHS 
AEGNEFWSAL LEKAYAKVNG SYEALSGGST SEGFEDFTGG VTEWYELRKA PSDLYQIILK 
ALERGSLLGC SIDISSVLDM EAITFKKLVK GHAYSVTGAK QVNYRGQVVS LIRMRNPWGE 
VEWTGAWSDS SSEWNNVDPY ERDQLRVKME DGEFWMSFRD FMREFTRLEI CNLTPDALKS 
RTIRKWNTTL YEGTWRRGST AGGCRNYPAT FWVNPQFKIR LDETDDPDDY GDRESGCSFV 
LALMQKHRRR ERRFGRDMET IGFAVYEVPP ELVGQPAVHL KRDFFLANAS RARSEQFINL 
REVSTRFRLP PGEYVVVPST FEPNKEGDFV LRFFSEKSAG TVELDDQIQA NLPDEQVLSE 
EEIDENFKAL FRQLAGEDME ISVKELRTIL NRIISKHKDL RTKGFSLESC RSMVNLMDRD 
GNGKLGLVEF NILWNRIRNY LSIFRKFDLD KSGSMSAYEM RMAIESAGFK LNKKLYELII 
TRYSEPDLAV DFDNFVCCLV RLETMFRFFK TLDTDLDGVV TFDLFKWLQL TMFA

Genular Protein ID: 3087462350

Symbol: B4DWH5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DWH5

Database IDs:

ARBA 21 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 3 InterPro 11 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 SMART 2 SUPFAM 3

Sequence Information:

  • Length: 660
  • Mass: 75835
  • Checksum: D7BE7773AC75929D
  • Sequence:
    • MRMPSSTWAR IMSSCGCDAC RVGPSSVMRP SPRYPRAWVT RTWVPIPPRP MASSGSVPRN 
CWLLAAIASL TLNDTLLHRV VPHGQSFQNG YAGIFHFQLW QFGEWVDVVV DDLLPIKDGK 
LVFVHSAEGN EFWSALLEKA YAKVNGSYEA LSGGSTSEGF EDFTGGVTEW YELRKAPSDL 
YQIILKALER GSLLGCSIDI SSVLDMEAIT FKKLVKGHAY SVTGAKQVNY RGQVVSLIRM 
RNPWGEVEWT GAWSDSSSEW NNVDPYERDQ LRVKMEDGEF WMSFRDFMRE FTRLEICNLT 
PDALKSRTIR KWNTTLYEGT WRRGSTAGGC RNYPATFWVN PQFKIRLDET DDPDDYGDRE 
SGCSFVLALM QKHRRRERRF GRDMETIGFA VYEVPPELVG QPAVHLKRDF FLANASRARS 
EQFINLREVS TRFRLPPGEY VVVPSTFEPN KEGDFVLRFF SEKSAGTVEL DDQIQANLPD 
EQVLSEEEID ENFKALFRQL AGEDMEISVK ELRTILNRII SKHKDLRTKG FSLESCRSMV 
NLMDRDGNGK LGLVEFNILW NRIRNYLSIF RKFDLDKSGS MSAYEMRMAI ESAGFKLNKK 
LYELIITRYS EPDLAVDFDN FVCCLVRLET MFRFFKTLDT DLDGVVTFDL FKWLQLTMFA

Genular Protein ID: 1092034388

Symbol: B2RDI5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2RDI5

Database IDs:

ARBA 22 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 3 InterPro 12 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 SMART 2 SUPFAM 3

Sequence Information:

  • Length: 714
  • Mass: 81897
  • Checksum: C583A49958C137CE
  • Sequence:
    • MSEEIITPVY CTGVSAQVQK QRARELGLGR HENAIKYLGQ DYEQLRVRCL QSGTLFRDEA 
FPPVPQSLGY KDLGPNSSKT YGIKWKRPTE LLSNPQFIVD GATRTDICQG ALGDCWLLAA 
IASLTLNDTL LHRVVPHGQS FQNGYAGIFH FQLWQFGEWV DVVVDDLLPI KDGKLVFVHS 
AEGNEFWSAL LEKAYAKVNG SYEALSGGST SEGFEDFTGG VTEWYELRKA PSDLYQIILK 
ALERGSLLGC SIDISSVLDM EAITFKKLVK GHAYSVTGAK QVNYRGQVVS LIRMRNPWGE 
VEWTGAWSDS SSEWNNVDPY ERDQLRVKME DGEFWMSFRD FMREFTRLEI CNLTPDALKS 
RTIRKWNTTL YEGTWRRGST AGGCRNYPAT FWVNPQFKIR LDETDDPDDY GDRESGCSFV 
LALMQKHRRR ERRFGCDMET IGFTVYEVPP ELVGQPAVHL KRDFFLANAS RARSEQFINL 
REVSTRFRLP PGEYVVVPST FEPNKEGDFV LRFFSEKSAG TVELDDQIQA NLPDEQVLSE 
EEIDENFKAL FRQLAGEDME ISVKELRTIL NRIISKHKDL RTKGFSLESC RSMVNLMDRD 
GNGKLGLVEF NILWNRIWNY LSIFRKFDLD KSGSMSAYEM RMAIESAGFK LNKKLYELII 
TRYSEPDLAV DFDNFVCCLV RLETMFRFFK TLDTDLDGVV TFDLFKWLQL TMFA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.