Details for: CAV1

Gene ID: 857

Symbol: CAV1

Ensembl ID: ENSG00000105974

Description: caveolin 1

Associated with

Other Information

Genular Protein ID: 978574568

Symbol: CAV1_HUMAN

Name: Caveolin-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1360410

Title: The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles.

PubMed ID: 1360410

DOI: 10.1016/0014-5793(92)81458-x

PubMed ID: 10086342

Title: Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines.

PubMed ID: 10086342

DOI: 10.1038/sj.onc.1202491

PubMed ID: 10218480

Title: Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines.

PubMed ID: 10218480

DOI: 10.1016/s0014-5793(99)00365-8

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15219854

Title: N-terminal processing and modifications of caveolin-1 in caveolae from human adipocytes.

PubMed ID: 15219854

DOI: 10.1016/j.bbrc.2004.05.196

PubMed ID: 15242332

Title: Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.

PubMed ID: 15242332

DOI: 10.1042/bj20040647

PubMed ID: 8632005

Title: Phosphorylation of caveolin by src tyrosine kinases. The alpha-isoform of caveolin is selectively phosphorylated by v-Src in vivo.

PubMed ID: 8632005

DOI: 10.1074/jbc.271.7.3863

PubMed ID: 11751885

Title: Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx.

PubMed ID: 11751885

DOI: 10.1074/jbc.m108537200

PubMed ID: 11865038

Title: Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex.

PubMed ID: 11865038

DOI: 10.1242/jcs.115.4.827

PubMed ID: 12531427

Title: c-Abl is required for oxidative stress-induced phosphorylation of caveolin-1 on tyrosine 14.

PubMed ID: 12531427

DOI: 10.1016/s0898-6568(02)00090-6

PubMed ID: 16807357

Title: Translocation of endothelial nitric-oxide synthase involves a ternary complex with caveolin-1 and NOSTRIN.

PubMed ID: 16807357

DOI: 10.1091/mbc.e05-08-0709

PubMed ID: 16501093

Title: The rotavirus enterotoxin NSP4 directly interacts with the caveolar structural protein caveolin-1.

PubMed ID: 16501093

DOI: 10.1128/jvi.80.6.2842-2854.2006

PubMed ID: 17287217

Title: Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1.

PubMed ID: 17287217

DOI: 10.1074/jbc.m609157200

PubMed ID: 18211975

Title: Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy.

PubMed ID: 18211975

DOI: 10.1210/jc.2007-1328

PubMed ID: 18237401

Title: Heterozygous CAV1 frameshift mutations (MIM 601047) in patients with atypical partial lipodystrophy and hypertriglyceridemia.

PubMed ID: 18237401

DOI: 10.1186/1476-511x-7-3

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19262564

Title: SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function.

PubMed ID: 19262564

DOI: 10.1038/emboj.2009.46

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22474227

Title: Whole exome sequencing to identify a novel gene (caveolin-1) associated with human pulmonary arterial hypertension.

PubMed ID: 22474227

DOI: 10.1161/circgenetics.111.961888

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24576892

Title: Caveolin-1 interacts with ATP binding cassette transporter G1 (ABCG1) and regulates ABCG1-mediated cholesterol efflux.

PubMed ID: 24576892

DOI: 10.1016/j.bbalip.2014.02.002

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25588833

Title: Cavin3 interacts with cavin1 and caveolin1 to increase surface dynamics of caveolae.

PubMed ID: 25588833

DOI: 10.1242/jcs.161463

PubMed ID: 25893292

Title: Syntenin regulates TGF-beta1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-beta type I receptor internalization.

PubMed ID: 25893292

DOI: 10.1038/onc.2015.100

PubMed ID: 28593998

Title: The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation.

PubMed ID: 28593998

DOI: 10.1038/ncomms15502

PubMed ID: 12368209

Title: Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia.

PubMed ID: 12368209

DOI: 10.1016/s0002-9440(10)64412-4

PubMed ID: 21822278

Title: Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations.

PubMed ID: 21822278

DOI: 10.1038/ncb2301

PubMed ID: 23335559

Title: Ubiquitination of the N-terminal region of caveolin-1 regulates endosomal sorting by the VCP/p97 AAA-ATPase.

PubMed ID: 23335559

DOI: 10.1074/jbc.m112.429076

PubMed ID: 25556234

Title: New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein.

PubMed ID: 25556234

DOI: 10.1074/mcp.m114.044107

Sequence Information:

  • Length: 178
  • Mass: 20472
  • Checksum: 2424DE9B5E6521D5
  • Sequence:
  • MSGGKYVDSE GHLYTVPIRE QGNIYKPNNK AMADELSEKQ VYDAHTKEID LVNRDPKHLN 
    DDVVKIDFED VIAEPEGTHS FDGIWKASFT TFTVTKYWFY RLLSALFGIP MALIWGIYFA 
    ILSFLHIWAV VPCIKSFLIE IQCISRVYSI YVHTVCDPLF EAVGKIFSNV RINLQKEI

Genular Protein ID: 2883065047

Symbol: Q59E85_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 217
  • Mass: 25069
  • Checksum: 220BFA69EEDE7BF2
  • Sequence:
  • LSERLVRFRA RGFPRRQADF SSLVFLFAFF LPPPLPPSPS WPSALRPLQG HLYTVPIREQ 
    GNIYKPNNKA MADELSEKQV YDAHTKEIDL VNRDPKHLND DVVKIDFEDV IAEPEGTHSF 
    DGIWKASFTT FTVTKYWFYR LLSALFGIPM ALIWGIYFAI LSFLHIWAVV PCIKSFLIEI 
    QCISRVYSIY VHTVCDPLFE AVGKIFSNVR INLQKEI

Genular Protein ID: 4202660448

Symbol: Q7Z4F3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 147
  • Mass: 17011
  • Checksum: 1A7D908D1C072A47
  • Sequence:
  • MADELSEKQV YDAHTKEIDL VNRDPKHLND DVVKIDFEDV IAEPEGTHSF DGIWKASFTT 
    FTVTKYWFYR LLSALFGIPM ALIWGIYFAI LSFLHIWAVV PCIKSFLIEI QCTSRVYSIY 
    VHTVCDPLFE AVGKIFSNVR INLQKEI

Genular Protein ID: 4004908550

Symbol: A9XTE5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 176
  • Mass: 20068
  • Checksum: 39A8184FA6C3A71B
  • Sequence:
  • HGAVAVGAGH LYTVPIREQG NIYKPNNKAM ADELSEKQVY DAHTKEIDLV NRDPKHLNDD 
    VVKIDFEDVI AEPEGTHSFD GIWKASFTTF TVTKYWFYRL LSALFGIPMA LIWGIYFAIL 
    SFLHIWAVVP CIKSFLIEIQ CTSRVYSIYV HTVCDPLFEA VGKIFSNVRI NLQKEI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.