Details for: CAV3

Gene ID: 859

Symbol: CAV3

Ensembl ID: ENSG00000182533

Description: caveolin 3

Associated with

Other Information

Genular Protein ID: 3488070543

Symbol: CAV3_HUMAN

Name: Caveolin-3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9537420

Title: Mutations in the caveolin-3 gene cause autosomal dominant limb-girdle muscular dystrophy.

PubMed ID: 9537420

DOI: 10.1038/ng0498-365

PubMed ID: 9545514

Title: Molecular cloning of human caveolin 3.

PubMed ID: 9545514

DOI: 10.1016/s0925-4439(97)00095-1

PubMed ID: 9536092

Title: Caveolin-3 in muscular dystrophy.

PubMed ID: 9536092

DOI: 10.1093/hmg/7.5.871

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10988290

Title: Caveolin-3 directly interacts with the C-terminal tail of beta -dystroglycan. Identification of a central WW-like domain within caveolin family members.

PubMed ID: 10988290

DOI: 10.1074/jbc.m005321200

PubMed ID: 11532985

Title: The sarcolemmal proteins dysferlin and caveolin-3 interact in skeletal muscle.

PubMed ID: 11532985

DOI: 10.1093/hmg/10.17.1761

PubMed ID: 19262564

Title: SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function.

PubMed ID: 19262564

DOI: 10.1038/emboj.2009.46

PubMed ID: 21362625

Title: Caveolin-3 undergoes SUMOylation by the SUMO E3 ligase PIASy: sumoylation affects G-protein-coupled receptor desensitization.

PubMed ID: 21362625

DOI: 10.1074/jbc.m110.214270

PubMed ID: 24567387

Title: MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by alpha1-adrenergic receptors.

PubMed ID: 24567387

DOI: 10.1073/pnas.1315359111

PubMed ID: 26497963

Title: The coiled-coil domain of MURC/cavin-4 is involved in membrane trafficking of caveolin-3 in cardiomyocytes.

PubMed ID: 26497963

DOI: 10.1152/ajpheart.00446.2015

PubMed ID: 11001938

Title: Dissociation of the dystroglycan complex in caveolin-3-deficient limb girdle muscular dystrophy.

PubMed ID: 11001938

DOI: 10.1093/oxfordjournals.hmg.a018926

PubMed ID: 10746614

Title: Mutation in the CAV3 gene causes partial caveolin-3 deficiency and hyperCKemia.

PubMed ID: 10746614

DOI: 10.1212/wnl.54.6.1373

PubMed ID: 11251997

Title: Mutations in the caveolin-3 gene: when are they pathogenic?

PubMed ID: 11251997

DOI: 10.1002/1096-8628(2001)9999:9999<::aid-ajmg1168>3.0.co;2-o

PubMed ID: 11431690

Title: Mutations in CAV3 cause mechanical hyperirritability of skeletal muscle in rippling muscle disease.

PubMed ID: 11431690

DOI: 10.1038/90050

PubMed ID: 11756609

Title: A sporadic case of rippling muscle disease caused by a de novo caveolin-3 mutation.

PubMed ID: 11756609

DOI: 10.1212/wnl.57.12.2273

PubMed ID: 12082049

Title: Familial isolated hyperCKaemia associated with a new mutation in the caveolin-3 (CAV-3) gene.

PubMed ID: 12082049

DOI: 10.1136/jnnp.73.1.65

PubMed ID: 11805270

Title: Mutation in the caveolin-3 gene causes a peculiar form of distal myopathy.

PubMed ID: 11805270

DOI: 10.1212/wnl.58.2.323

PubMed ID: 12557291

Title: Consequences of a novel caveolin-3 mutation in a large German family.

PubMed ID: 12557291

DOI: 10.1002/ana.10442

PubMed ID: 12666119

Title: Homozygous mutations in caveolin-3 cause a severe form of rippling muscle disease.

PubMed ID: 12666119

DOI: 10.1002/ana.10501

PubMed ID: 12939441

Title: Limb-girdle muscular dystrophy in a 71-year-old woman with an R27Q mutation in the CAV3 gene.

PubMed ID: 12939441

DOI: 10.1212/01.wnl.0000076486.57572.5c

PubMed ID: 14663034

Title: A CAV3 microdeletion differentially affects skeletal muscle and myocardium.

PubMed ID: 14663034

DOI: 10.1212/01.wnl.0000097320.35982.03

PubMed ID: 14672715

Title: Identification and functional analysis of a caveolin-3 mutation associated with familial hypertrophic cardiomyopathy.

PubMed ID: 14672715

DOI: 10.1016/j.bbrc.2003.11.101

PubMed ID: 15099591

Title: A novel mutation in the caveolin-3 gene causing familial isolated hyperCKaemia.

PubMed ID: 15099591

DOI: 10.1016/j.nmd.2004.01.006

PubMed ID: 15564037

Title: Two novel CAV3 gene mutations in Japanese families.

PubMed ID: 15564037

DOI: 10.1016/j.nmd.2004.08.008

PubMed ID: 15668980

Title: Autosomal recessive rippling muscle disease with homozygous CAV3 mutations.

PubMed ID: 15668980

DOI: 10.1002/ana.20350

PubMed ID: 15580566

Title: Molecular and muscle pathology in a series of caveolinopathy patients.

PubMed ID: 15580566

DOI: 10.1002/humu.20119

PubMed ID: 16458928

Title: A new missense mutation in caveolin-3 gene causes rippling muscle disease.

PubMed ID: 16458928

DOI: 10.1016/j.jns.2005.11.032

PubMed ID: 17060380

Title: Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome.

PubMed ID: 17060380

DOI: 10.1161/circulationaha.106.635268

PubMed ID: 17275750

Title: Novel mechanism for sudden infant death syndrome: persistent late sodium current secondary to mutations in caveolin-3.

PubMed ID: 17275750

DOI: 10.1016/j.hrthm.2006.11.030

Sequence Information:

  • Length: 151
  • Mass: 17259
  • Checksum: C695E14F5B8F4753
  • Sequence:
  • MMAEEHTDLE AQIVKDIHCK EIDLVNRDPK NINEDIVKVD FEDVIAEPVG TYSFDGVWKV 
    SYTTFTVSKY WCYRLLSTLL GVPLALLWGF LFACISFCHI WAVVPCIKSY LIEIQCISHI 
    YSLCIRTFCN PLFAALGQVC SSIKVVLRKE V

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.