Details for: OR5G1P

Gene ID: 8591

Symbol: OR5G1P

Ensembl ID: ENSG00000181296

Description: olfactory receptor family 5 subfamily G member 1 pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0163
    Cell Significance Index: 0.7600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Pseudogene status:** OR5G1P is classified as a pseudogene, which means it has undergone significant mutations and is no longer capable of encoding a functional protein. 2. **Expression in salivary gland cells:** The gene is significantly expressed in acinar cells of the salivary gland, suggesting a specific role in these cells. 3. **Olfactory receptor family 5 subfamily G:** OR5G1P is a member of the olfactory receptor family 5, which is responsible for detecting odorant molecules in the air. 4. **Ensembl ID:** ENSG00000181296, which is a unique identifier for this gene in the Ensembl database. **Pathways and Functions:** While the function of OR5G1P remains unclear, its expression in salivary gland cells suggests a potential role in the regulation of saliva production or composition. Several possible pathways may be involved: 1. **Saliva production:** OR5G1P may play a role in regulating the production of saliva, which is essential for maintaining oral health and digestion. 2. **Sensory perception:** The olfactory receptor family 5 is responsible for detecting odorant molecules in the air. OR5G1P may be involved in the sensory perception of these molecules, particularly in the salivary gland. 3. **Cell signaling:** OR5G1P may be involved in cell signaling pathways, regulating the behavior of acinar cells in the salivary gland. **Clinical Significance:** The identification of OR5G1P as a pseudogene with significant expression in salivary gland cells has several implications for clinical research: 1. **Oral health:** Understanding the role of OR5G1P in saliva production and composition may lead to the development of new therapeutic strategies for oral diseases, such as xerostomia (dry mouth). 2. **Dental caries:** OR5G1P may play a role in the regulation of saliva composition, which is essential for preventing dental caries. 3. **Cancer research:** The expression of OR5G1P in salivary gland cells may have implications for cancer research, particularly in the development of new therapeutic strategies for salivary gland cancer. In conclusion, while the function of OR5G1P remains unclear, its expression in salivary gland cells suggests a potential role in the regulation of saliva production or composition. Further research is needed to fully understand the implications of this gene and its potential applications in clinical research.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.