Details for: RUNX1T1

Gene ID: 862

Symbol: RUNX1T1

Ensembl ID: ENSG00000079102

Description: RUNX1 partner transcriptional co-repressor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 556.4298
    Cell Significance Index: -86.5500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 343.8686
    Cell Significance Index: -87.2200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 175.4205
    Cell Significance Index: -82.8200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 70.3188
    Cell Significance Index: -86.7000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 21.9739
    Cell Significance Index: -86.7100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 6.3468
    Cell Significance Index: 108.7700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 6.0393
    Cell Significance Index: 117.8700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 5.3385
    Cell Significance Index: 128.0300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 5.1376
    Cell Significance Index: 315.7800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 4.4676
    Cell Significance Index: 273.9100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 3.7631
    Cell Significance Index: 46.6800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.9010
    Cell Significance Index: 581.9500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.2602
    Cell Significance Index: 810.6800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 2.2236
    Cell Significance Index: 170.6400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 2.0108
    Cell Significance Index: 42.0900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.4741
    Cell Significance Index: 1019.5100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.4452
    Cell Significance Index: 54.7300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.4011
    Cell Significance Index: 63.5100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.8389
    Cell Significance Index: 23.9400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.7948
    Cell Significance Index: 16.9900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.7535
    Cell Significance Index: 39.5600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.7415
    Cell Significance Index: 32.8000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6565
    Cell Significance Index: 592.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.3757
    Cell Significance Index: 170.5200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3661
    Cell Significance Index: 36.2200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3089
    Cell Significance Index: 42.4200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1296
    Cell Significance Index: 21.0800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.1274
    Cell Significance Index: 2.5200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1245
    Cell Significance Index: 234.3900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1208
    Cell Significance Index: 6.7800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0926
    Cell Significance Index: 142.4800
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.0765
    Cell Significance Index: 1.1000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0680
    Cell Significance Index: 125.3400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0515
    Cell Significance Index: 70.0300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0026
    Cell Significance Index: 0.0900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0716
    Cell Significance Index: -53.0600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0795
    Cell Significance Index: -2.2900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.1073
    Cell Significance Index: -1.6600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1107
    Cell Significance Index: -81.1400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1132
    Cell Significance Index: -71.9000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1200
    Cell Significance Index: -90.8000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1240
    Cell Significance Index: -69.9400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.1330
    Cell Significance Index: -58.8100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1402
    Cell Significance Index: -9.4300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1449
    Cell Significance Index: -90.4700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1572
    Cell Significance Index: -85.8500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1886
    Cell Significance Index: -24.1800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.1952
    Cell Significance Index: -21.2300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.2380
    Cell Significance Index: -45.3000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2382
    Cell Significance Index: -3.4200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2626
    Cell Significance Index: -75.5600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2967
    Cell Significance Index: -4.3800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.3450
    Cell Significance Index: -62.1900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3929
    Cell Significance Index: -12.5900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3981
    Cell Significance Index: -83.8400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.4277
    Cell Significance Index: -84.8800
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.4818
    Cell Significance Index: -7.3300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.5262
    Cell Significance Index: -89.8600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.5478
    Cell Significance Index: -79.6300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.5577
    Cell Significance Index: -38.5700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.5984
    Cell Significance Index: -73.5800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.6469
    Cell Significance Index: -83.5800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6651
    Cell Significance Index: -69.2500
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.6747
    Cell Significance Index: -9.0000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.7013
    Cell Significance Index: -81.7300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.7373
    Cell Significance Index: -12.3400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.7556
    Cell Significance Index: -77.1800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.7916
    Cell Significance Index: -90.6900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.8177
    Cell Significance Index: -49.0900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.8313
    Cell Significance Index: -18.0100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.9435
    Cell Significance Index: -20.6600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.9611
    Cell Significance Index: -30.6100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -1.0209
    Cell Significance Index: -14.6200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.0285
    Cell Significance Index: -81.4600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.0465
    Cell Significance Index: -21.0100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.1209
    Cell Significance Index: -83.5400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.1572
    Cell Significance Index: -24.5600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -1.1606
    Cell Significance Index: -12.0900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.2926
    Cell Significance Index: -42.3200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.3206
    Cell Significance Index: -34.7300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.3318
    Cell Significance Index: -69.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.4171
    Cell Significance Index: -66.0700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.4619
    Cell Significance Index: -68.7100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -1.4663
    Cell Significance Index: -63.7600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.4698
    Cell Significance Index: -92.6400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.6226
    Cell Significance Index: -84.2900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.7558
    Cell Significance Index: -61.5100
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -1.7819
    Cell Significance Index: -21.6000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -1.8059
    Cell Significance Index: -13.9200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.9597
    Cell Significance Index: -48.8900
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -1.9725
    Cell Significance Index: -21.4900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -2.0099
    Cell Significance Index: -56.1700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -2.0631
    Cell Significance Index: -59.1400
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -2.1187
    Cell Significance Index: -26.4200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -2.1844
    Cell Significance Index: -56.1500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -2.2212
    Cell Significance Index: -81.5400
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -2.2257
    Cell Significance Index: -15.0800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -2.2622
    Cell Significance Index: -34.0900
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -2.2943
    Cell Significance Index: -29.4200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -2.3815
    Cell Significance Index: -59.5300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RUNX1T1 is a transcriptional co-repressor that interacts with the RUNX1 transcription factor to regulate gene expression. It possesses a unique structure, comprising a zinc finger domain and a coiled-coil motif, which enables it to bind to RUNX1 and modulate its transcriptional activity. RUNX1T1 is specifically expressed in cells of the nervous system, including neurons, glial cells, and brainstem motor neurons. Its expression is also observed in non-neuronal cells, such as ciliary muscle cells and rod bipolar cells. **Pathways and Functions:** RUNX1T1 is involved in several key pathways, including: 1. **DNA-binding transcription factor binding**: RUNX1T1 interacts with RUNX1 to bind to specific DNA sequences, regulating the transcription of target genes. 2. **DNA-templated transcription**: RUNX1T1 modulates the transcription of genes involved in cell differentiation, survival, and development. 3. **Negative regulation of DNA-templated transcription**: RUNX1T1 acts as a co-repressor, inhibiting the transcription of genes that promote cell proliferation and differentiation. 4. **Negative regulation of fat cell differentiation**: RUNX1T1 regulates the expression of genes involved in adipogenesis, preventing the differentiation of precursor cells into adipocytes. 5. **Nuclear matrix and nucleoplasm**: RUNX1T1 is associated with the nuclear matrix and nucleoplasm, influencing the organization and dynamics of chromatin. **Clinical Significance:** Dysregulation of RUNX1T1 expression has been implicated in various human diseases, including: 1. **Acute Lymphoblastic Leukemia (ALL)**: RUNX1T1 is involved in the regulation of RUNX1 expression, which is frequently mutated in ALL. Altered RUNX1T1 expression may contribute to the development of leukemia. 2. **Neurodevelopmental disorders**: RUNX1T1 is expressed in neuronal cells and is involved in the regulation of gene expression in the nervous system. Abnormalities in RUNX1T1 expression may contribute to neurodevelopmental disorders, such as autism spectrum disorder and schizophrenia. 3. **Cancer**: RUNX1T1 is overexpressed in certain types of cancer, including breast cancer and colon cancer. Its expression may influence tumor progression and metastasis. In conclusion, RUNX1T1 is a critical transcriptional co-repressor that regulates gene expression in neuronal and non-neuronal cells. Its dysregulation has been implicated in various human diseases, highlighting the importance of understanding its function and regulation in normal and pathological processes. Further studies are necessary to elucidate the mechanisms by which RUNX1T1 influences gene expression and to explore its potential as a therapeutic target.

Genular Protein ID: 2281951961

Symbol: MTG8_HUMAN

Name: Protein CBFA2T1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8334990

Title: The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

PubMed ID: 8334990

DOI: 10.1002/j.1460-2075.1993.tb05933.x

PubMed ID: 9661669

Title: Structure and expression of the human MTG8/ETO gene.

PubMed ID: 9661669

DOI: 10.1016/s0378-1119(98)00141-3

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8137293

Title: The ETO portion of acute myeloid leukemia t(8;21) fusion transcript encodes a highly evolutionarily conserved putative transcription factor.

PubMed ID: 8137293

PubMed ID: 7919324

Title: Alternative, out-of-frame runt/MTG8 transcripts are encoded by the derivative (8) chromosome in the t(8;21) of acute myeloid leukemia M2.

PubMed ID: 7919324

PubMed ID: 10973986

Title: Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription.

PubMed ID: 10973986

DOI: 10.1083/jcb.150.5.939

PubMed ID: 10688654

Title: The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein.

PubMed ID: 10688654

DOI: 10.1128/mcb.20.6.2075-2086.2000

PubMed ID: 12242670

Title: The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t(16; 21)-positive myeloid malignancies.

PubMed ID: 12242670

DOI: 10.1038/sj.onc.1205882

PubMed ID: 12559562

Title: The ETO (MTG8) gene family.

PubMed ID: 12559562

DOI: 10.1016/s0378-1119(02)01172-1

PubMed ID: 15203199

Title: The MTG proteins: chromatin repression players with a passion for networking.

PubMed ID: 15203199

DOI: 10.1016/j.ygeno.2004.02.011

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19202074

Title: Transforming activity of AML1-ETO is independent of CBFbeta and ETO interaction but requires formation of homo-oligomeric complexes.

PubMed ID: 19202074

DOI: 10.1073/pnas.0810558106

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23251453

Title: Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.

PubMed ID: 23251453

DOI: 10.1371/journal.pone.0051205

PubMed ID: 16616331

Title: The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity.

PubMed ID: 16616331

DOI: 10.1016/j.ccr.2006.03.012

PubMed ID: 16803958

Title: The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain.

PubMed ID: 16803958

DOI: 10.1073/pnas.0603463103

PubMed ID: 17560331

Title: Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.

PubMed ID: 17560331

DOI: 10.1016/j.ccr.2007.04.010

PubMed ID: 17572682

Title: A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription.

PubMed ID: 17572682

DOI: 10.1038/nsmb1258

PubMed ID: 23812588

Title: A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.

PubMed ID: 23812588

DOI: 10.1038/nature12287

PubMed ID: 7541640

Title: Identification of two transcripts of AML1/ETO-fused gene in t(8;21) leukemic cells and expression of wild-type ETO gene in hematopoietic cells.

PubMed ID: 7541640

DOI: 10.1002/gcc.2870130105

PubMed ID: 8353289

Title: Junctions of the AML1/MTG8(ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction.

PubMed ID: 8353289

PubMed ID: 1423235

Title: Transcriptionally active chimeric gene derived from the fusion of the AML1 gene and a novel gene on chromosome 8 in t(8;21) leukemic cells.

PubMed ID: 1423235

DOI: 10.1016/0165-4608(92)90384-k

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 604
  • Mass: 67566
  • Checksum: C3D2452F96E65679
  • Sequence:
  • MISVKRNTWR ALSLVIGDCR KKGNFEYCQD RTEKHSTMPD SPVDVKTQSR LTPPTMPPPP 
    TTQGAPRTSS FTPTTLTNGT SHSPTALNGA PSPPNGFSNG PSSSSSSSLA NQQLPPACGA 
    RQLSKLKRFL TTLQQFGNDI SPEIGERVRT LVLGLVNSTL TIEEFHSKLQ EATNFPLRPF 
    VIPFLKANLP LLQRELLHCA RLAKQNPAQY LAQHEQLLLD ASTTSPVDSS ELLLDVNENG 
    KRRTPDRTKE NGFDREPLHS EHPSKRPCTI SPGQRYSPNN GLSYQPNGLP HPTPPPPQHY 
    RLDDMAIAHH YRDSYRHPSH RDLRDRNRPM GLHGTRQEEM IDHRLTDREW AEEWKHLDHL 
    LNCIMDMVEK TRRSLTVLRR CQEADREELN YWIRRYSDAE DLKKGGGSSS SHSRQQSPVN 
    PDPVALDAHR EFLHRPASGY VPEEIWKKAE EAVNEVKRQA MTELQKAVSE AERKAHDMIT 
    TERAKMERTV AEAKRQAAED ALAVINQQED SSESCWNCGR KASETCSGCN TARYCGSFCQ 
    HKDWEKHHHI CGQTLQAQQQ GDTPAVSSSV TPNSGAGSPM DTPPAATPRS TTPGTPSTIE 
    TTPR

Genular Protein ID: 1622400483

Symbol: W8FW32_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 567
  • Mass: 63212
  • Checksum: 44AADF2EC7032050
  • Sequence:
  • MPDSPVDVKT QSRLTPPTMP PPPTTQGAPR TSSFTPTTLT NGTSHSPTAL NGAPSPPNGF 
    SNGPSSSSSS SLANQQLPPA CGARQLSKLK RFLTTLQQFG NDISPEIGER VRTLVLGLVN 
    STLTIEEFHS KLQEATNFPL RPFVIPFLKA NLPLLQRELL HCARLAKQNP AQYLAQHEQL 
    LLDASTTSPV DSSELLLDVN ENGKRRTPDR TKENGFDREP LHSEHPSKRP CTISPGQRYS 
    PNNGLSYQPN GLPHPTPPPP QHYRLDDMAI AHHYRDSYRH PSHRDLRDRN RPMGLHGTRQ 
    EEMIDHRLTD REWAEEWKHL DHLLNCIMDM VEKTRRSLTV LRRCQEADRE ELNYWIRRYS 
    DAEDLKKGGG SSSSHSRQQS PVNPDPVALD AHREFLHRPA SGYVPEEIWK KAEEAVNEVK 
    RQAMTELQKA VSEAERKAHD MITTERAKME RTVAEAKRQA AEDALAVINQ QEDSSESCWN 
    CGRKASETCS GCNTARYCGS FCQHKDWEKH HHICGQTLQA QQQGDTPAVS SSVTPNSGAG 
    SPMDTPPAAT PRSTTPGTPS TIETTPR

Genular Protein ID: 511160732

Symbol: B2R6I9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 577
  • Mass: 64369
  • Checksum: E2AAB735120EDC07
  • Sequence:
  • MPDRTEKHST MPDSPVDVKT QSRLTPPTMP PPPTTQGAPR TSSFTPTTLT NGTSHSPTAL 
    NGAPSPPNGF SNGPSSSSSS SLANQQLPPA CGARQLSKLK RFLTTLQQFG NDISPEIGER 
    VRTLVLGLVN STLTIEEFHS KLQEATNFPL RPFVIPFLKA NLPLLQRELL HCARLAKQSP 
    AQYLAQHEQL LLDASTTSPV DSSELLLDVN ENGKRRTPDR TKENGFDREP LHSEHPSKRP 
    CTISPGQRYS PNNGLSYQPN GLPHPTPPPP QHYRLDDMAI AHHYRDSYRH PSHRDLRDRN 
    RPMGLHGTRQ EEMIDHRLTD REWAEEWKHL DHLLNCIMDM VEKTRRSLTV LRRCQEADRE 
    ELNYWIRRYS DAEDLKKGGG SSSSHSRQQS PVNPDPVALD AHREFLHRPA SGYVPEEIWK 
    KAEEAVNEVK RQAMTELQKA VSEAERKAHD MITTERAKME RTVAEAKRQA AEDALAVINQ 
    QEDSSESCWN CGRKASETCS GCNTARYCGS FCQHKDWEKH HHICGQTLQA QQQGDTPAVS 
    SSVTPNSGAG SPMDTPPAAT PRSTTPGTPS TIETTPR

Genular Protein ID: 237844170

Symbol: E5RH72_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 584
  • Mass: 65085
  • Checksum: 581085B1DF3AB0BA
  • Sequence:
  • MVGLSGPVQY RTEKHSTMPD SPVDVKTQSR LTPPTMPPPP TTQGAPRTSS FTPTTLTNGT 
    SHSPTALNGA PSPPNGFSNG PSSSSSSSLA NQQLPPACGA RQLSKLKRFL TTLQQFGNDI 
    SPEIGERVRT LVLGLVNSTL TIEEFHSKLQ EATNFPLRPF VIPFLKANLP LLQRELLHCA 
    RLAKQNPAQY LAQHEQLLLD ASTTSPVDSS ELLLDVNENG KRRTPDRTKE NGFDREPLHS 
    EHPSKRPCTI SPGQRYSPNN GLSYQPNGLP HPTPPPPQHY RLDDMAIAHH YRDSYRHPSH 
    RDLRDRNRPM GLHGTRQEEM IDHRLTDREW AEEWKHLDHL LNCIMDMVEK TRRSLTVLRR 
    CQEADREELN YWIRRYSDAE DLKKGGGSSS SHSRQQSPVN PDPVALDAHR EFLHRPASGY 
    VPEEIWKKAE EAVNEVKRQA MTELQKAVSE AERKAHDMIT TERAKMERTV AEAKRQAAED 
    ALAVINQQED SSESCWNCGR KASETCSGCN TARYCGSFCQ HKDWEKHHHI CGQTLQAQQQ 
    GDTPAVSSSV TPNSGAGSPM DTPPAATPRS TTPGTPSTIE TTPR

Genular Protein ID: 3000419755

Symbol: A0A0A0MSU1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 663
  • Mass: 74192
  • Checksum: E6D792FD9B56D7C9
  • Sequence:
  • MCHPDKAFTS DKLQCVFNEY KAAVWVPPRP RPLSRAPLPE AGGENLHLKI SRVRKRNLPF 
    VVWGEEEAST PGLDAISHHL CYPDRTHRDR TEKHSTMPDS PVDVKTQSRL TPPTMPPPPT 
    TQGAPRTSSF TPTTLTNGTS HSPTALNGAP SPPNGFSNGP SSSSSSSLAN QQLPPACGAR 
    QLSKLKRFLT TLQQFGNDIS PEIGERVRTL VLGLVNSTLT IEEFHSKLQE ATNFPLRPFV 
    IPFLKANLPL LQRELLHCAR LAKQNPAQYL AQHEQLLLDA STTSPVDSSE LLLDVNENGK 
    RRTPDRTKEN GFDREPLHSE HPSKRPCTIS PGQRYSPNNG LSYQPNGLPH PTPPPPQHYR 
    LDDMAIAHHY RDSYRHPSHR DLRDRNRPMG LHGTRQEEMI DHRLTDREWA EEWKHLDHLL 
    NCIMDMVEKT RRSLTVLRRC QEADREELNY WIRRYSDAED LKKGGGSSSS HSRQQSPVNP 
    DPVALDAHRE FLHRPASGYV PEEIWKKAEE AVNEVKRQAM TELQKAVSEA ERKAHDMITT 
    ERAKMERTVA EAKRQAAEDA LAVINQQEDS SESCWNCGRK ASETCSGCNT ARYCGSFCQH 
    KDWEKHHHIC GQTLQAQQQG DTPAVSSSVT PNSGAGSPMD TPPAATPRST TPGTPSTIET 
    TPR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.