Details for: RUNX1T1

Gene ID: 862

Symbol: RUNX1T1

Ensembl ID: ENSG00000079102

Description: RUNX1 partner transcriptional co-repressor 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 7.55
    Marker Score: 39616
  • Cell Name: granule cell (CL0000120)
    Fold Change: 7.48
    Marker Score: 56429
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 6.55
    Marker Score: 15046
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 5.89
    Marker Score: 19762
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 3.97
    Marker Score: 134228
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 3.35
    Marker Score: 18015
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 3.27
    Marker Score: 1901
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 3.23
    Marker Score: 1552
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.01
    Marker Score: 6601
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 2.98
    Marker Score: 1559
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.87
    Marker Score: 911
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.87
    Marker Score: 1672
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.86
    Marker Score: 1591
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.83
    Marker Score: 56229
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.72
    Marker Score: 12572
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.71
    Marker Score: 5223
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 2.69
    Marker Score: 1391.5
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 2.58
    Marker Score: 1447
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.54
    Marker Score: 56847
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.52
    Marker Score: 2899
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.47
    Marker Score: 93791
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.25
    Marker Score: 865
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.23
    Marker Score: 82191
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 2.19
    Marker Score: 1444
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.17
    Marker Score: 2067
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 2.16
    Marker Score: 1169
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.14
    Marker Score: 20147
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 2.1
    Marker Score: 2950
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.04
    Marker Score: 125296
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.03
    Marker Score: 7845
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.98
    Marker Score: 1975
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.95
    Marker Score: 506
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 1.95
    Marker Score: 25680
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.91
    Marker Score: 1142
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.89
    Marker Score: 17966
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.81
    Marker Score: 3046
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.8
    Marker Score: 6416
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.8
    Marker Score: 38442
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.79
    Marker Score: 7307
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 1.79
    Marker Score: 1362.5
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.77
    Marker Score: 17810
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.76
    Marker Score: 15148
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.73
    Marker Score: 17849
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.71
    Marker Score: 2117
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 1.69
    Marker Score: 2110
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.64
    Marker Score: 927
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.62
    Marker Score: 3282.5
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.6
    Marker Score: 23916
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.6
    Marker Score: 584
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.59
    Marker Score: 1156
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.59
    Marker Score: 12187
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 1.57
    Marker Score: 476
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.55
    Marker Score: 766
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.53
    Marker Score: 643
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 167282
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.45
    Marker Score: 1255
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.43
    Marker Score: 798
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.43
    Marker Score: 834
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.41
    Marker Score: 3313
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 1.39
    Marker Score: 1489
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: 1.38
    Marker Score: 1977.5
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.31
    Marker Score: 2027
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.31
    Marker Score: 14732
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.29
    Marker Score: 20168
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.28
    Marker Score: 3353
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.27
    Marker Score: 1528
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 1.26
    Marker Score: 1186
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.25
    Marker Score: 1516
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.25
    Marker Score: 1506
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.22
    Marker Score: 280
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.21
    Marker Score: 5018
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.2
    Marker Score: 1496
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.2
    Marker Score: 1743
  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.2
    Marker Score: 1271
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.18
    Marker Score: 2065
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.17
    Marker Score: 2385.5
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 1.17
    Marker Score: 249
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.17
    Marker Score: 289
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.17
    Marker Score: 3175
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 1.16
    Marker Score: 1090
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 1.14
    Marker Score: 432
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.14
    Marker Score: 724
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.14
    Marker Score: 4784
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.13
    Marker Score: 1517
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.12
    Marker Score: 351
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.12
    Marker Score: 3191.5
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.07
    Marker Score: 703
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.06
    Marker Score: 289
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.06
    Marker Score: 334
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.05
    Marker Score: 714
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.05
    Marker Score: 4414.5
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.04
    Marker Score: 430
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.03
    Marker Score: 788
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.03
    Marker Score: 261
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.01
    Marker Score: 607.5
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 1
    Marker Score: 1377
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71767
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47992
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30404
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 502

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Other Information

**Key characteristics:** * Regulates the expression of genes involved in neuronal development, survival, and function. * Acts as a negative regulator of DNA-templated transcription by binding to specific DNA sequences and repressing transcription. * Plays a role in the differentiation of various cell types, including neurons, astrocytes, and oligodendrocytes. * Contributes to the development and maintenance of the nervous system and the maintenance of brain function. **Pathways and functions:** * **Dna-binding transcription:** RUNX1T1 binds to DNA sequences in the promoters of target genes and represses their transcription through the recruitment of coactivators. * **Dna-templated transcription:** When bound to DNA, RUNX1T1 forms a heterodimeric complex with DNAMYC, leading to the inhibition of transcription. * **Dna binding:** RUNX1T1 can also bind to DNA directly and inhibit transcription. * **Metal ion binding:** RUNX1T1 is sensitive to calcium ions and can be regulated by calcium signaling pathways. * **Negative regulation of fat cell differentiation:** RUNX1T1 is expressed in high levels in neurons and is essential for the differentiation of sympathetic and sensory neurons from neural stem cells. * **Negative regulation of fat cell differentiation:** RUNX1T1 also plays a role in the regulation of fat cell differentiation, as it inhibits the expression of genes involved in fat metabolism. **Clinical significance:** Mutations in RUNX1T1 have been linked to several neurological disorders, including autism, schizophrenia, and epilepsy. These mutations can disrupt the regulation of neuronal development and function, leading to the symptoms of these disorders. **Additional notes:** * RUNX1T1 is a highly conserved protein with homologs in other species. * It is a multifunctional protein that can interact with various proteins involved in transcription, translation, and cell signaling. * Its expression is regulated by a complex interplay of genetic, environmental, and epigenetic factors.

Genular Protein ID: 2281951961

Symbol: MTG8_HUMAN

Name: Protein CBFA2T1

UniProtKB Accession Codes:

Q06455 B7Z4P4 E7EPN4 O14784 Q06456 Q14873 Q16239 Q16346 Q16347 Q6IBL1 Q6NXH1 Q7Z4J5 Q92479 Q9BRZ0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CTD 1 ChEBI 8 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 44 EPD 1 Ensembl 10 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 14 PDBsum 9 PIR 2 PRINTS 2 PRO 1 PROSITE 3 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 RefSeq 26 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8334990

Title: The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

PubMed ID: 8334990

DOI: 10.1002/j.1460-2075.1993.tb05933.x

PubMed ID: 9661669

Title: Structure and expression of the human MTG8/ETO gene.

PubMed ID: 9661669

DOI: 10.1016/s0378-1119(98)00141-3

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8137293

Title: The ETO portion of acute myeloid leukemia t(8;21) fusion transcript encodes a highly evolutionarily conserved putative transcription factor.

PubMed ID: 8137293

PubMed ID: 7919324

Title: Alternative, out-of-frame runt/MTG8 transcripts are encoded by the derivative (8) chromosome in the t(8;21) of acute myeloid leukemia M2.

PubMed ID: 7919324

PubMed ID: 10973986

Title: Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription.

PubMed ID: 10973986

DOI: 10.1083/jcb.150.5.939

PubMed ID: 10688654

Title: The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein.

PubMed ID: 10688654

DOI: 10.1128/mcb.20.6.2075-2086.2000

PubMed ID: 12242670

Title: The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t(16; 21)-positive myeloid malignancies.

PubMed ID: 12242670

DOI: 10.1038/sj.onc.1205882

PubMed ID: 12559562

Title: The ETO (MTG8) gene family.

PubMed ID: 12559562

DOI: 10.1016/s0378-1119(02)01172-1

PubMed ID: 15203199

Title: The MTG proteins: chromatin repression players with a passion for networking.

PubMed ID: 15203199

DOI: 10.1016/j.ygeno.2004.02.011

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19202074

Title: Transforming activity of AML1-ETO is independent of CBFbeta and ETO interaction but requires formation of homo-oligomeric complexes.

PubMed ID: 19202074

DOI: 10.1073/pnas.0810558106

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23251453

Title: Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.

PubMed ID: 23251453

DOI: 10.1371/journal.pone.0051205

PubMed ID: 16616331

Title: The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity.

PubMed ID: 16616331

DOI: 10.1016/j.ccr.2006.03.012

PubMed ID: 16803958

Title: The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain.

PubMed ID: 16803958

DOI: 10.1073/pnas.0603463103

PubMed ID: 17560331

Title: Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.

PubMed ID: 17560331

DOI: 10.1016/j.ccr.2007.04.010

PubMed ID: 17572682

Title: A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription.

PubMed ID: 17572682

DOI: 10.1038/nsmb1258

PubMed ID: 23812588

Title: A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.

PubMed ID: 23812588

DOI: 10.1038/nature12287

PubMed ID: 7541640

Title: Identification of two transcripts of AML1/ETO-fused gene in t(8;21) leukemic cells and expression of wild-type ETO gene in hematopoietic cells.

PubMed ID: 7541640

DOI: 10.1002/gcc.2870130105

PubMed ID: 8353289

Title: Junctions of the AML1/MTG8(ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction.

PubMed ID: 8353289

PubMed ID: 1423235

Title: Transcriptionally active chimeric gene derived from the fusion of the AML1 gene and a novel gene on chromosome 8 in t(8;21) leukemic cells.

PubMed ID: 1423235

DOI: 10.1016/0165-4608(92)90384-k

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 604
  • Mass: 67566
  • Checksum: C3D2452F96E65679
  • Sequence:
    • MISVKRNTWR ALSLVIGDCR KKGNFEYCQD RTEKHSTMPD SPVDVKTQSR LTPPTMPPPP 
TTQGAPRTSS FTPTTLTNGT SHSPTALNGA PSPPNGFSNG PSSSSSSSLA NQQLPPACGA 
RQLSKLKRFL TTLQQFGNDI SPEIGERVRT LVLGLVNSTL TIEEFHSKLQ EATNFPLRPF 
VIPFLKANLP LLQRELLHCA RLAKQNPAQY LAQHEQLLLD ASTTSPVDSS ELLLDVNENG 
KRRTPDRTKE NGFDREPLHS EHPSKRPCTI SPGQRYSPNN GLSYQPNGLP HPTPPPPQHY 
RLDDMAIAHH YRDSYRHPSH RDLRDRNRPM GLHGTRQEEM IDHRLTDREW AEEWKHLDHL 
LNCIMDMVEK TRRSLTVLRR CQEADREELN YWIRRYSDAE DLKKGGGSSS SHSRQQSPVN 
PDPVALDAHR EFLHRPASGY VPEEIWKKAE EAVNEVKRQA MTELQKAVSE AERKAHDMIT 
TERAKMERTV AEAKRQAAED ALAVINQQED SSESCWNCGR KASETCSGCN TARYCGSFCQ 
HKDWEKHHHI CGQTLQAQQQ GDTPAVSSSV TPNSGAGSPM DTPPAATPRS TTPGTPSTIE 
TTPR

Genular Protein ID: 3000419755

Symbol: A0A0A0MSU1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MSU1

Database IDs:

ARBA 8 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 3 Proteomes 2 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 663
  • Mass: 74192
  • Checksum: E6D792FD9B56D7C9
  • Sequence:
    • MCHPDKAFTS DKLQCVFNEY KAAVWVPPRP RPLSRAPLPE AGGENLHLKI SRVRKRNLPF 
VVWGEEEAST PGLDAISHHL CYPDRTHRDR TEKHSTMPDS PVDVKTQSRL TPPTMPPPPT 
TQGAPRTSSF TPTTLTNGTS HSPTALNGAP SPPNGFSNGP SSSSSSSLAN QQLPPACGAR 
QLSKLKRFLT TLQQFGNDIS PEIGERVRTL VLGLVNSTLT IEEFHSKLQE ATNFPLRPFV 
IPFLKANLPL LQRELLHCAR LAKQNPAQYL AQHEQLLLDA STTSPVDSSE LLLDVNENGK 
RRTPDRTKEN GFDREPLHSE HPSKRPCTIS PGQRYSPNNG LSYQPNGLPH PTPPPPQHYR 
LDDMAIAHHY RDSYRHPSHR DLRDRNRPMG LHGTRQEEMI DHRLTDREWA EEWKHLDHLL 
NCIMDMVEKT RRSLTVLRRC QEADREELNY WIRRYSDAED LKKGGGSSSS HSRQQSPVNP 
DPVALDAHRE FLHRPASGYV PEEIWKKAEE AVNEVKRQAM TELQKAVSEA ERKAHDMITT 
ERAKMERTVA EAKRQAAEDA LAVINQQEDS SESCWNCGRK ASETCSGCNT ARYCGSFCQH 
KDWEKHHHIC GQTLQAQQQG DTPAVSSSVT PNSGAGSPMD TPPAATPRST TPGTPSTIET 
TPR

Genular Protein ID: 1622400483

Symbol: W8FW32_HUMAN

Name: N/A

UniProtKB Accession Codes:

W8FW32

Database IDs:

ARBA 8 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 ExpressionAtlas 1 GO 4 Gene3D 3 GenomeRNAi 1 HOGENOM 1 InterPro 6 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 5 PROSITE-ProRule 1 Pfam 3 RefSeq 8 SAM 2 SMART 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Sequence Information:

  • Length: 567
  • Mass: 63212
  • Checksum: 44AADF2EC7032050
  • Sequence:
    • MPDSPVDVKT QSRLTPPTMP PPPTTQGAPR TSSFTPTTLT NGTSHSPTAL NGAPSPPNGF 
SNGPSSSSSS SLANQQLPPA CGARQLSKLK RFLTTLQQFG NDISPEIGER VRTLVLGLVN 
STLTIEEFHS KLQEATNFPL RPFVIPFLKA NLPLLQRELL HCARLAKQNP AQYLAQHEQL 
LLDASTTSPV DSSELLLDVN ENGKRRTPDR TKENGFDREP LHSEHPSKRP CTISPGQRYS 
PNNGLSYQPN GLPHPTPPPP QHYRLDDMAI AHHYRDSYRH PSHRDLRDRN RPMGLHGTRQ 
EEMIDHRLTD REWAEEWKHL DHLLNCIMDM VEKTRRSLTV LRRCQEADRE ELNYWIRRYS 
DAEDLKKGGG SSSSHSRQQS PVNPDPVALD AHREFLHRPA SGYVPEEIWK KAEEAVNEVK 
RQAMTELQKA VSEAERKAHD MITTERAKME RTVAEAKRQA AEDALAVINQ QEDSSESCWN 
CGRKASETCS GCNTARYCGS FCQHKDWEKH HHICGQTLQA QQQGDTPAVS SSVTPNSGAG 
SPMDTPPAAT PRSTTPGTPS TIETTPR

Genular Protein ID: 511160732

Symbol: B2R6I9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2R6I9

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 4 Gene3D 3 Genevisible 1 GenomeRNAi 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 2 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 577
  • Mass: 64369
  • Checksum: E2AAB735120EDC07
  • Sequence:
    • MPDRTEKHST MPDSPVDVKT QSRLTPPTMP PPPTTQGAPR TSSFTPTTLT NGTSHSPTAL 
NGAPSPPNGF SNGPSSSSSS SLANQQLPPA CGARQLSKLK RFLTTLQQFG NDISPEIGER 
VRTLVLGLVN STLTIEEFHS KLQEATNFPL RPFVIPFLKA NLPLLQRELL HCARLAKQSP 
AQYLAQHEQL LLDASTTSPV DSSELLLDVN ENGKRRTPDR TKENGFDREP LHSEHPSKRP 
CTISPGQRYS PNNGLSYQPN GLPHPTPPPP QHYRLDDMAI AHHYRDSYRH PSHRDLRDRN 
RPMGLHGTRQ EEMIDHRLTD REWAEEWKHL DHLLNCIMDM VEKTRRSLTV LRRCQEADRE 
ELNYWIRRYS DAEDLKKGGG SSSSHSRQQS PVNPDPVALD AHREFLHRPA SGYVPEEIWK 
KAEEAVNEVK RQAMTELQKA VSEAERKAHD MITTERAKME RTVAEAKRQA AEDALAVINQ 
QEDSSESCWN CGRKASETCS GCNTARYCGS FCQHKDWEKH HHICGQTLQA QQQGDTPAVS 
SSVTPNSGAG SPMDTPPAAT PRSTTPGTPS TIETTPR

Genular Protein ID: 237844170

Symbol: E5RH72_HUMAN

Name: N/A

UniProtKB Accession Codes:

E5RH72 A0A087WWT6

Database IDs:

ARBA 8 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 ChiTaRS 1 EMBL 6 EPD 1 Ensembl 2 GO 3 Gene3D 3 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PRINTS 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 1 SUPFAM 2 UCSC 2 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 584
  • Mass: 65085
  • Checksum: 581085B1DF3AB0BA
  • Sequence:
    • MVGLSGPVQY RTEKHSTMPD SPVDVKTQSR LTPPTMPPPP TTQGAPRTSS FTPTTLTNGT 
SHSPTALNGA PSPPNGFSNG PSSSSSSSLA NQQLPPACGA RQLSKLKRFL TTLQQFGNDI 
SPEIGERVRT LVLGLVNSTL TIEEFHSKLQ EATNFPLRPF VIPFLKANLP LLQRELLHCA 
RLAKQNPAQY LAQHEQLLLD ASTTSPVDSS ELLLDVNENG KRRTPDRTKE NGFDREPLHS 
EHPSKRPCTI SPGQRYSPNN GLSYQPNGLP HPTPPPPQHY RLDDMAIAHH YRDSYRHPSH 
RDLRDRNRPM GLHGTRQEEM IDHRLTDREW AEEWKHLDHL LNCIMDMVEK TRRSLTVLRR 
CQEADREELN YWIRRYSDAE DLKKGGGSSS SHSRQQSPVN PDPVALDAHR EFLHRPASGY 
VPEEIWKKAE EAVNEVKRQA MTELQKAVSE AERKAHDMIT TERAKMERTV AEAKRQAAED 
ALAVINQQED SSESCWNCGR KASETCSGCN TARYCGSFCQ HKDWEKHHHI CGQTLQAQQQ 
GDTPAVSSSV TPNSGAGSPM DTPPAATPRS TTPGTPSTIE TTPR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.