Details for: CBFA2T3

Gene ID: 863

Symbol: CBFA2T3

Ensembl ID: ENSG00000129993

Description: CBFA2/RUNX1 partner transcriptional co-repressor 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 43.1386
    Cell Significance Index: -6.7100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 15.5914
    Cell Significance Index: -8.0200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 14.3903
    Cell Significance Index: -3.6500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 5.8396
    Cell Significance Index: -7.2000
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 2.5894
    Cell Significance Index: 16.5300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.9184
    Cell Significance Index: -7.5700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.5398
    Cell Significance Index: -3.3700
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 1.5000
    Cell Significance Index: 12.6000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.4456
    Cell Significance Index: 36.9300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.2417
    Cell Significance Index: 26.4500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.1927
    Cell Significance Index: 76.9500
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.8379
    Cell Significance Index: 6.9300
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.8251
    Cell Significance Index: 11.5800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.8150
    Cell Significance Index: 21.8000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7869
    Cell Significance Index: 85.6000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7227
    Cell Significance Index: 117.5500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6586
    Cell Significance Index: 39.5400
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.6422
    Cell Significance Index: 4.9500
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 0.5170
    Cell Significance Index: 3.4300
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: 0.4772
    Cell Significance Index: 3.4300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4467
    Cell Significance Index: 30.8900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.4128
    Cell Significance Index: 60.0000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3389
    Cell Significance Index: 67.9900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.3032
    Cell Significance Index: 6.6400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2887
    Cell Significance Index: 34.0500
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.2760
    Cell Significance Index: 3.9700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2555
    Cell Significance Index: 13.2700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2324
    Cell Significance Index: 8.8000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2225
    Cell Significance Index: 9.8400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2194
    Cell Significance Index: 3.7600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1904
    Cell Significance Index: 171.9000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1794
    Cell Significance Index: 17.7500
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.1755
    Cell Significance Index: 1.7700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1490
    Cell Significance Index: 53.4400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1328
    Cell Significance Index: 8.1600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1160
    Cell Significance Index: 2.9000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0913
    Cell Significance Index: 6.1400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0741
    Cell Significance Index: 12.6600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0561
    Cell Significance Index: 2.6200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0551
    Cell Significance Index: 1.5000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0515
    Cell Significance Index: 96.9700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0382
    Cell Significance Index: 7.2700
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.0303
    Cell Significance Index: 0.5000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0272
    Cell Significance Index: 3.3500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0245
    Cell Significance Index: 37.7800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0229
    Cell Significance Index: 42.1700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0207
    Cell Significance Index: 0.9400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.0184
    Cell Significance Index: 0.3400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0125
    Cell Significance Index: 2.2500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0090
    Cell Significance Index: 0.2200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0076
    Cell Significance Index: 0.2200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0022
    Cell Significance Index: -3.0100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0045
    Cell Significance Index: -1.9700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0052
    Cell Significance Index: -0.6100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0070
    Cell Significance Index: -0.1000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0072
    Cell Significance Index: -3.9500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0079
    Cell Significance Index: -5.8800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0082
    Cell Significance Index: -5.2200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0093
    Cell Significance Index: -0.1400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0097
    Cell Significance Index: -5.4600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0099
    Cell Significance Index: -7.5100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0105
    Cell Significance Index: -7.7000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0126
    Cell Significance Index: -7.8800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0137
    Cell Significance Index: -1.8900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0143
    Cell Significance Index: -6.4700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0182
    Cell Significance Index: -0.5200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0189
    Cell Significance Index: -0.4100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0197
    Cell Significance Index: -5.6600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0270
    Cell Significance Index: -1.7000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0272
    Cell Significance Index: -1.4300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0297
    Cell Significance Index: -5.8900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0319
    Cell Significance Index: -4.0900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0371
    Cell Significance Index: -7.8100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0429
    Cell Significance Index: -0.8900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0481
    Cell Significance Index: -3.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0490
    Cell Significance Index: -2.7500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0503
    Cell Significance Index: -1.6100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0506
    Cell Significance Index: -1.0600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0535
    Cell Significance Index: -6.9100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0537
    Cell Significance Index: -5.5900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0573
    Cell Significance Index: -6.5700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0672
    Cell Significance Index: -6.8700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0694
    Cell Significance Index: -1.8600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0740
    Cell Significance Index: -5.6800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0888
    Cell Significance Index: -3.1200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0973
    Cell Significance Index: -7.7100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0973
    Cell Significance Index: -2.5000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1025
    Cell Significance Index: -7.6400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1072
    Cell Significance Index: -5.0400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1077
    Cell Significance Index: -3.0100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1146
    Cell Significance Index: -3.6500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1210
    Cell Significance Index: -7.4200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.1222
    Cell Significance Index: -2.1600
  • Cell Name: sensory neuron (CL0000101)
    Fold Change: -0.1231
    Cell Significance Index: -0.7000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1243
    Cell Significance Index: -4.3200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1267
    Cell Significance Index: -4.4400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1432
    Cell Significance Index: -4.6900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1470
    Cell Significance Index: -2.4600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1492
    Cell Significance Index: -2.9500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1579
    Cell Significance Index: -1.6400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CBFA2T3 is a transcriptional co-repressor that interacts with transcription factors to regulate gene expression. Its ability to bind to DNA and other proteins enables it to modulate the transcription of target genes involved in cell proliferation, differentiation, and survival. This co-repressor activity is essential for maintaining the balance between cell growth and survival, particularly in the context of hematopoiesis and immune cell development. **Pathways and Functions:** CBFA2T3 is involved in several key pathways, including: 1. **Granulocyte Differentiation**: CBFA2T3 plays a critical role in regulating the expression of genes involved in granulocyte differentiation, highlighting its importance in hematopoiesis. 2. **Glycolytic Process**: This gene influences the regulation of glycolytic processes, which are essential for energy production in cells. 3. **Negative Regulation of Cell Population Proliferation**: CBFA2T3 acts as a co-repressor to regulate cell population proliferation, preventing uncontrolled cell growth. 4. **DNA-templated Transcription**: This gene is involved in the regulation of DNA-templated transcription, which is essential for gene expression. 5. **Regulation of Aerobic Respiration**: CBFA2T3 influences the regulation of aerobic respiration, an essential process for energy production in cells. **Clinical Significance:** The dysregulation of CBFA2T3 has been implicated in various diseases, including: 1. **Leukemia**: Mutations in CBFA2T3 have been associated with leukemias, highlighting its importance in hematopoiesis. 2. **Lymphoma**: This gene has been implicated in lymphoma development, emphasizing its role in immune cell regulation. 3. **Immune Dysregulation**: CBFA2T3 dysregulation has been linked to immune dysregulation, including autoimmune diseases and immunodeficiency disorders. In conclusion, CBFA2T3 is a complex gene that plays a multifaceted role in various cellular and immunological processes. Its dysregulation has been implicated in several diseases, highlighting the need for further research into its mechanisms of action and potential therapeutic applications.

Genular Protein ID: 2152887254

Symbol: MTG16_HUMAN

Name: Protein CBFA2T3

UniProtKB Accession Codes:

O75081 D3DX78 O60615 O60616 O60617 O75082 O75107 O75108 Q0P5Z6 Q6P5W6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChEBI 8 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 2 ExpressionAtlas 1 GO 14 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRINTS 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9596646

Title: The partner gene of AML1 in t(16;21) myeloid malignancies is a novel member of the MTG8(ETO) family.

PubMed ID: 9596646

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9790752

Title: CBFA2T1, a gene rearranged in human leukemia, is a member of a multigene family.

PubMed ID: 9790752

DOI: 10.1006/geno.1998.5429

PubMed ID: 10995019

Title: AML1-MTG16 fusion gene in therapy-related acute leukemia with t(16;21)(q24;q22): two new cases.

PubMed ID: 10995019

DOI: 10.1038/sj.leu.2401885

PubMed ID: 11224496

Title: AML1/MTG16 fusion gene from a t(16;21)(q24;q22) translocation in treatment-induced leukemia after breast cancer.

PubMed ID: 11224496

PubMed ID: 11533236

Title: ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain.

PubMed ID: 11533236

DOI: 10.1128/mcb.21.19.6470-6483.2001

PubMed ID: 12183414

Title: CBFA2T3 (MTG16) is a putative breast tumor suppressor gene from the breast cancer loss of heterozygosity region at 16q24.3.

PubMed ID: 12183414

PubMed ID: 11823486

Title: Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes.

PubMed ID: 11823486

DOI: 10.4049/jimmunol.168.4.1590

PubMed ID: 12242670

Title: The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t(16; 21)-positive myeloid malignancies.

PubMed ID: 12242670

DOI: 10.1038/sj.onc.1205882

PubMed ID: 12559562

Title: The ETO (MTG8) gene family.

PubMed ID: 12559562

DOI: 10.1016/s0378-1119(02)01172-1

PubMed ID: 15231665

Title: AML1-ETO decreases ETO-2 (MTG16) interactions with nuclear receptor corepressor, an effect that impairs granulocyte differentiation.

PubMed ID: 15231665

DOI: 10.1158/0008-5472.can-03-3689

PubMed ID: 15203199

Title: The MTG proteins: chromatin repression players with a passion for networking.

PubMed ID: 15203199

DOI: 10.1016/j.ygeno.2004.02.011

PubMed ID: 15470020

Title: A-kinase anchoring proteins interact with phosphodiesterases in T lymphocyte cell lines.

PubMed ID: 15470020

DOI: 10.4049/jimmunol.173.8.4806

PubMed ID: 15676213

Title: The leukemia-associated ETO homologues are differently expressed during hematopoietic differentiation.

PubMed ID: 15676213

DOI: 10.1016/j.exphem.2004.10.011

PubMed ID: 16616331

Title: The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity.

PubMed ID: 16616331

DOI: 10.1016/j.ccr.2006.03.012

PubMed ID: 16815842

Title: ErbB-4 s80 intracellular domain abrogates ETO2-dependent transcriptional repression.

PubMed ID: 16815842

DOI: 10.1074/jbc.m603998200

PubMed ID: 16966434

Title: ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription.

PubMed ID: 16966434

DOI: 10.1158/1541-7786.mcr-05-0249

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20138877

Title: Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner.

PubMed ID: 20138877

DOI: 10.1016/j.febslet.2010.02.007

PubMed ID: 23251453

Title: Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.

PubMed ID: 23251453

DOI: 10.1371/journal.pone.0051205

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23840896

Title: The transcriptional co-repressor myeloid translocation gene 16 inhibits glycolysis and stimulates mitochondrial respiration.

PubMed ID: 23840896

DOI: 10.1371/journal.pone.0068502

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25974097

Title: Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1.

PubMed ID: 25974097

DOI: 10.1371/journal.pone.0123725

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 653
  • Mass: 71192
  • Checksum: 0B72B602120FA5DE
  • Sequence:
    • MPASRLRDRA ASSASGSTCG SMSQTHPVLE SGLLASAGCS APRGPRKGGP APVDRKAKAS 
AMPDSPAEVK TQPRSTPPSM PPPPPAASQG ATRPPSFTPH THREDGPATL PHGRFHGCLK 
WSMVCLLMNG SSHSPTAING APCTPNGFSN GPATSSTASL STQHLPPACG ARQLSKLKRF 
LTTLQQFGSD ISPEIGERVR TLVLGLVNST LTIEEFHSKL QEATNFPLRP FVIPFLKANL 
PLLQRELLHC ARLAKQTPAQ YLAQHEQLLL DASASSPIDS SELLLEVNEN GKRRTPDRTK 
ENGSDRDPLH PEHLSKRPCT LNPAQRYSPS NGPPQPTPPP HYRLEDIAMA HHFRDAYRHP 
DPRELRERHR PLVVPGSRQE EVIDHKLTER EWAEEWKHLN NLLNCIMDMV EKTRRSLTVL 
RRCQEADREE LNHWARRYSD AEDTKKGPAP AAARPRSSSA GPEGPQLDVP REFLPRTLTG 
YVPEDIWRKA EEAVNEVKRQ AMSELQKAVS DAERKAHELI TTERAKMERA LAEAKRQASE 
DALTVINQQE DSSESCWNCG RKASETCSGC NAARYCGSFC QHRDWEKHHH VCGQSLQGPT 
AVVADPVPGP PEAAHSLGPS LPVGAASPSE AGSAGPSRPG SPSPPGPLDT VPR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.