Details for: CBLB
Associated with
Other Information
Genular Protein ID: 2587945829
Symbol: CBLB_HUMAN
Name: E3 ubiquitin-protein ligase CBL-B
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7784085
Title: Cloning and characterization of cbl-b: a SH3 binding protein with homology to the c-cbl proto-oncogene.
PubMed ID: 7784085
PubMed ID: 9399639
Title: Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation.
PubMed ID: 9399639
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12880961
Title: Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma.
PubMed ID: 12880961
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 10022120
Title: Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation.
PubMed ID: 10022120
PubMed ID: 10086340
Title: cbl-b inhibits epidermal growth factor receptor signaling.
PubMed ID: 10086340
PubMed ID: 11087752
Title: Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.
PubMed ID: 11087752
PubMed ID: 11375397
Title: Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex.
PubMed ID: 11375397
PubMed ID: 11526404
Title: Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.
PubMed ID: 11526404
DOI: 10.1038/ni0901-870
PubMed ID: 12177062
Title: CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases.
PubMed ID: 12177062
PubMed ID: 14661060
Title: Cbl-c suppresses v-Src-induced transformation through ubiquitin-dependent protein degradation.
PubMed ID: 14661060
PubMed ID: 15273720
Title: Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b.
PubMed ID: 15273720
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19549985
Title: PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation.
PubMed ID: 19549985
PubMed ID: 20525694
Title: The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme.
PubMed ID: 20525694
PubMed ID: 29237719
Title: IFT20 modulates ciliary PDGFRalpha signaling by regulating the stability of Cbl E3 ubiquitin ligases.
PubMed ID: 29237719
PubMed ID: 16228008
Title: Cbl promotes clustering of endocytic adaptor proteins.
PubMed ID: 16228008
DOI: 10.1038/nsmb1000
PubMed ID: 17020880
Title: Atypical polyproline recognition by the CMS N-terminal Src homology 3 domain.
PubMed ID: 17020880
PubMed ID: 17679095
Title: Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b.
PubMed ID: 17679095
Sequence Information:
- Length: 982
- Mass: 109450
- Checksum: B4E307D31B9F0779
- Sequence:
MANSMNGRNP GGRGGNPRKG RILGIIDAIQ DAVGPPKQAA ADRRTVEKTW KLMDKVVRLC QNPKLQLKNS PPYILDILPD TYQHLRLILS KYDDNQKLAQ LSENEYFKIY IDSLMKKSKR AIRLFKEGKE RMYEEQSQDR RNLTKLSLIF SHMLAEIKAI FPNGQFQGDN FRITKADAAE FWRKFFGDKT IVPWKVFRQC LHEVHQISSG LEAMALKSTI DLTCNDYISV FEFDIFTRLF QPWGSILRNW NFLAVTHPGY MAFLTYDEVK ARLQKYSTKP GSYIFRLSCT RLGQWAIGYV TGDGNILQTI PHNKPLFQAL IDGSREGFYL YPDGRSYNPD LTGLCEPTPH DHIKVTQEQY ELYCEMGSTF QLCKICAEND KDVKIEPCGH LMCTSCLTAW QESDGQGCPF CRCEIKGTEP IIVDPFDPRD EGSRCCSIID PFGMPMLDLD DDDDREESLM MNRLANVRKC TDRQNSPVTS PGSSPLAQRR KPQPDPLQIP HLSLPPVPPR LDLIQKGIVR SPCGSPTGSP KSSPCMVRKQ DKPLPAPPPP LRDPPPPPPE RPPPIPPDNR LSRHIHHVES VPSRDPPMPL EAWCPRDVFG TNQLVGCRLL GEGSPKPGIT ASSNVNGRHS RVGSDPVLMR KHRRHDLPLE GAKVFSNGHL GSEEYDVPPR LSPPPPVTTL LPSIKCTGPL ANSLSEKTRD PVEEDDDEYK IPSSHPVSLN SQPSHCHNVK PPVRSCDNGH CMLNGTHGPS SEKKSNIPDL SIYLKGDVFD SASDPVPLPP ARPPTRDNPK HGSSLNRTPS DYDLLIPPLG EDAFDALPPS LPPPPPPARH SLIEHSKPPG SSSRPSSGQD LFLLPSDPFV DLASGQVPLP PARRLPGENV KTNRTSQDYD QLPSCSDGSQ APARPPKPRP RRTAPEIHHR KPHGPEAALE NVDAKIAKLM GEGYAFEEVK RALEIAQNNV EVARSILREF AFPPPVSPRL NL
Genular Protein ID: 1373687835
Symbol: B4DYP3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 960
- Mass: 107083
- Checksum: 330B04D6638D0BBD
- Sequence:
MALAPGSDAH AHLPPLIELK FQMANSMNGR NPGGRGGNPR KGRILGIIDA IQDAVGPPKQ AAADRRTVEK TWKLMDKVVR LCQNPKLQLK NSPPYILDIL PDTYQHLRLI LSKYDDNQKL AQLSENEYFK IYIDSLMKKS KRAIRLFKEG KERMYEEQSQ DRRNLTKLSL IFSHMLAEIK AIFPNGQFQG DNFRITKADA AEFWRKFFGD KTIVPWKVFR QCLHEVHQIS SGLEAMALKS TIDLTCNDYI SVFEFDIFTR LFQPWGSILR NWNFLAVTHP GYMAFLTYDE VKARLQKYST KPGSYIFRLS CTRLGQWAIG YVTGDGNILQ TIPHNKPLFQ ALIDGSREGF YLYPDGRSYN PDLTGLCEPT PHDHIKVTQE QYELYCEMGS TFQLCKICAE NDKDVKIEPC GHLMCTSCLT AWQESDGQGC PFCRCEIKGT EPIIVDPFDP RDEGSRCCSI IDPFGMPMLD LDDDDDREES LMMNRLANVR KCTDRQNSPV TSPGSSPLAQ RRKPQPDPLQ IPHLSLPPVP PRLDLIQKGI VRSPCGSPTG SPKSSPCMVR KQDKPLPAPP PPLRDPPPPP PERPPPIPPD NRLSRHIHHV ESVPSRDPPM PLEAWCPRDV FGTNQLVGCR LLGEGSPKPG ITASSNVNGR HSRVGSDPVL MRKHRRHDLP LEGAKVFSNG HLGSEEYDVP PRLSPPPPVT TLLPSIKCTG PLANSLSEKT RDPVEEDDDE YKIPSSHPVS LNSQPSHCHN VKPPVRSCDN GHCMLNGTHG PSSEKKSNIP DLSIYLKGED AFDALPPSLP PPPPPARHSL IEHSKPPGSS SRPSSGQDLF LLPSDPFVDL ASGQVPLPPA RRLPGENVKT NRTSQDYDQL PSCSDGSQAP ARPPKPRPRR TAPEIHHRKP HGPEAALENV DAKIAKLMGE GYAFEEVKRA LEIAQNNVEV ARSILREFAF PPPVSPRLNL
Genular Protein ID: 1943509495
Symbol: B3KSS7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 405
- Mass: 44242
- Checksum: C1D94AF5EB185CF1
- Sequence:
MAETLVVEEE IPEKVEFWVL LMLFRMQLDP LSKLPQIAKP GITASSNVNG RHSRVGSDPV LMRKHRRHDL PLEGAKVFSN GHLGSEEYDV PPRLSPPPPV TTLLPSIKCT GPLANSLSEK TRDPVEEDDD EYKIPSSHPV SLNSQPSHCH NVKPPVRSCD NGHCMLNGTH GPSSEKKSNI PDLSIYLKGD VFDSASDPVP LPPARPPTRD NPKHGSSLNR TPSDYDLLIP PLGEDAFDAL PPSLPPPPPP ARHSLIEHSK PPGSSSRPSS GQDLFLLPSD PFVDLASGQV PLPPARRLPG ENVKTNRTSQ DYDQLPSCSD GSQASARPPK PRPRRTAPEI HHRKPHGPEA ALENVDAKIA KLMGEGYAFE EVKRALEIAQ NNVEVARSIL REFAFPPPVS PRLNL
Genular Protein ID: 3583767040
Symbol: B7ZAG1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 960
- Mass: 106994
- Checksum: 14CF74D4DCABFE5B
- Sequence:
MALAPGPDAH AHLPPLIELK FQMANSMNGR NPGGRGGNPR KGRILGIIDA IQDAVGPPKQ AAADRRTVEK TWKLMDKVVR LCQNPKLQLK NSPPYILDIL PDTYQHLRLI LSKYDDNQKL AQLSENEYFK IYIDSLMKKS KRAIRLFKEG KERMYEEQSQ DRRNLTKLSL IFSHMLAEIK AIFPNGQFQG DNFRITKADA AEFWRKFFGD KTIVPWKVFR QCLHEVHQIS SGLEAMALKS TIDLTCNDYI SVFEFDIFTR LFQPWGSILR NWNFLAVTHP GYMAFLTYDE VKARLQKYST KPGSYIFRLS CTRLGQWAIG YVTGDGNILQ TIPHNKPLFQ ALIDGSREGF YLYPDGRSYN PDLTGLCEPT PHDHIKVTQE QYELYCEMGS TFQLCKICAE NDKDVKIEPC GHLMCTSCLT AWQESDGQGC PFCRCEIKGT EPIIVDPFDP RDEGSRCCSI IDPFGMPMLD LDDDDDREES LMMNRLANVR KCTDRQNSPV TSPGSSPLAQ RRKPQPDPLQ IPHLSLPPVP PRLDLIQKGI VRSPCGSPTG SPKSSPCMVR KQDKPLPAPP PPLGDPPPPP PERPPPIPPD NRLSRHIHHV ESVPSRDPPM PLEAWCPRDV FGTNQLVGCR LLGEGSPKPG ITASSNVNGR HSRVGSDPVL MRKHRRHDLP LEGAKVFSNG HLGSEEYDVP PRLSPPPPVT TLLPSIKCTG PLANSLSEKT RDPVEEDDDE YKIPSSHPVS LNSQPSHCHN VKPPVRSCDN GHCMLNGTHG PSSEKKSNIP DLSIYLKGED AFDALPPSLP PPPPPARHSL IEHSKPPGSS SRPSSGQDLF LLPSDPFVDL ASGQVPLPPA RRLPGENVKT NRTSQDYDQL PSCSDGSQAP ARPPKPRPRR TAPEIHHRKP HGPEAALENV DAKIAKLMGE GYAFEEVKRA LEIAQNNVEV ARSILREFAF PPPVSPRLNL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.