Details for: ACTN1

Gene ID: 87

Symbol: ACTN1

Ensembl ID: ENSG00000072110

Description: actinin alpha 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 368.1887
    Cell Significance Index: -57.2700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 211.5569
    Cell Significance Index: -53.6600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 123.0132
    Cell Significance Index: -49.9800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 121.4409
    Cell Significance Index: -57.3400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 109.1011
    Cell Significance Index: -56.1200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 52.6163
    Cell Significance Index: -50.2400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 46.5548
    Cell Significance Index: -57.4000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 21.4233
    Cell Significance Index: -57.3900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.9524
    Cell Significance Index: -55.1400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 14.5741
    Cell Significance Index: -57.5100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 13.5887
    Cell Significance Index: -29.7400
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 5.4162
    Cell Significance Index: 28.5000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.3910
    Cell Significance Index: 149.9900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.2094
    Cell Significance Index: 121.5300
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 3.0426
    Cell Significance Index: 18.7300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.9208
    Cell Significance Index: 201.9900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 2.6671
    Cell Significance Index: 30.3000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.5353
    Cell Significance Index: 508.5700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.3697
    Cell Significance Index: 176.6100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 2.2406
    Cell Significance Index: 39.6000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.6928
    Cell Significance Index: 45.2000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.6532
    Cell Significance Index: 126.8700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.6459
    Cell Significance Index: 44.8000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.5675
    Cell Significance Index: 73.6700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.5444
    Cell Significance Index: 306.5000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.5103
    Cell Significance Index: 195.1200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.4098
    Cell Significance Index: 505.6700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.3406
    Cell Significance Index: 218.0400
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.3171
    Cell Significance Index: 30.4300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.1652
    Cell Significance Index: 78.3500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.1507
    Cell Significance Index: 53.6500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.1019
    Cell Significance Index: 487.1600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.0067
    Cell Significance Index: 129.0500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9594
    Cell Significance Index: 117.9700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.9305
    Cell Significance Index: 127.7800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.7082
    Cell Significance Index: 321.4500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7048
    Cell Significance Index: 127.0600
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 0.7006
    Cell Significance Index: 6.0200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.6744
    Cell Significance Index: 368.3000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.6500
    Cell Significance Index: 449.5400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.5453
    Cell Significance Index: 6.5000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.5374
    Cell Significance Index: 38.0100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.4724
    Cell Significance Index: 6.7900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4515
    Cell Significance Index: 44.6600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.4275
    Cell Significance Index: 12.2000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4227
    Cell Significance Index: 19.1600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4022
    Cell Significance Index: 11.2400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.3765
    Cell Significance Index: 39.2000
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.3573
    Cell Significance Index: 2.2200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.3352
    Cell Significance Index: 9.6100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.3000
    Cell Significance Index: 5.5400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2779
    Cell Significance Index: 523.2300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.2428
    Cell Significance Index: 4.0900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2248
    Cell Significance Index: 42.7800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2162
    Cell Significance Index: 36.9200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1735
    Cell Significance Index: 5.0000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1686
    Cell Significance Index: 229.2500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1155
    Cell Significance Index: 177.8500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1023
    Cell Significance Index: 64.9400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0580
    Cell Significance Index: 0.9700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0501
    Cell Significance Index: 1.3400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0201
    Cell Significance Index: 2.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0033
    Cell Significance Index: 6.0200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0149
    Cell Significance Index: -11.0400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0349
    Cell Significance Index: -21.7800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0562
    Cell Significance Index: -42.5200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0582
    Cell Significance Index: -32.8400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0597
    Cell Significance Index: -43.7800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0790
    Cell Significance Index: -8.0700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0852
    Cell Significance Index: -4.4400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0852
    Cell Significance Index: -0.5200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0936
    Cell Significance Index: -5.9000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1082
    Cell Significance Index: -5.6200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1259
    Cell Significance Index: -26.5100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1365
    Cell Significance Index: -19.8500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1397
    Cell Significance Index: -4.9100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1654
    Cell Significance Index: -19.2700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1759
    Cell Significance Index: -50.6200
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.2679
    Cell Significance Index: -2.2500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3003
    Cell Significance Index: -34.4100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3008
    Cell Significance Index: -7.5200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3044
    Cell Significance Index: -34.7500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.4567
    Cell Significance Index: -53.8600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.4954
    Cell Significance Index: -31.9600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.5852
    Cell Significance Index: -8.6400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5954
    Cell Significance Index: -20.6900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.6129
    Cell Significance Index: -12.8300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6181
    Cell Significance Index: -32.4500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.6375
    Cell Significance Index: -9.4100
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.6519
    Cell Significance Index: -3.0100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6622
    Cell Significance Index: -52.4500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.7314
    Cell Significance Index: -21.4800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.7449
    Cell Significance Index: -15.8700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7523
    Cell Significance Index: -24.1000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.7611
    Cell Significance Index: -42.7100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.7951
    Cell Significance Index: -17.0000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.8226
    Cell Significance Index: -7.5800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.8536
    Cell Significance Index: -12.7900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9328
    Cell Significance Index: -57.1900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.9887
    Cell Significance Index: -31.4900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ACTN1 is a member of the actinin family of proteins, which are characterized by their ability to bind to actin filaments. ACTN1 is composed of three domains: the N-terminal domain, the central domain, and the C-terminal domain, which interact with actin filaments and other proteins. ACTN1 is highly expressed in muscle cells, epithelial cells, and other cell types, where it plays a crucial role in maintaining cell shape, motility, and adhesion. **Pathways and Functions:** ACTN1 is involved in a wide range of cellular processes, including: 1. **Cell adhesion**: ACTN1 interacts with integrins, focal adhesion proteins, and other adhesion molecules to regulate cell adhesion and migration. 2. **Cytoskeletal organization**: ACTN1 regulates the organization and dynamics of the actin cytoskeleton, influencing cell shape, motility, and signaling. 3. **Signaling**: ACTN1 interacts with various signaling proteins, including Rho GTPases, to regulate cell signaling pathways involved in proliferation, differentiation, and survival. 4. **Apoptosis**: ACTN1 regulates apoptosis by interacting with pro-apoptotic and anti-apoptotic proteins, influencing cell survival and death. **Clinical Significance:** ACTN1 has been implicated in various diseases, including: 1. **Muscular dystrophy**: ACTN1 mutations have been associated with muscular dystrophy, a group of genetic disorders characterized by progressive muscle weakness and degeneration. 2. **Cardiovascular disease**: ACTN1 has been linked to cardiovascular disease, including hypertension, atherosclerosis, and cardiac arrhythmias. 3. **Cancer**: ACTN1 has been implicated in cancer progression, including metastasis, invasion, and angiogenesis. 4. **Neurological disorders**: ACTN1 has been associated with neurological disorders, including Alzheimer's disease, Parkinson's disease, and stroke. **Significantly Expressed Cells:** ACTN1 is highly expressed in various cell types, including: 1. **Uterine smooth muscle cells**: ACTN1 regulates uterine contractions and labor. 2. **Myoepithelial cells of mammary gland**: ACTN1 maintains milk ejection and ductal contraction. 3. **Ciliary muscle cells**: ACTN1 regulates accommodation and focus in the eye. 4. **Smooth muscle cells of large intestine**: ACTN1 regulates bowel motility and secretion. **Proteins:** ACTN1_HUMAN (Alpha-actinin-1) is the primary protein product of the ACTN1 gene. In conclusion, ACTN1 is a multifaceted protein that plays a crucial role in various cellular processes, including cell adhesion, signaling, and cytoskeletal organization. Its dysregulation has been implicated in various diseases, including muscular dystrophy, cardiovascular disease, cancer, and neurological disorders. Further research on ACTN1 is necessary to fully understand its role in human disease and to develop therapeutic strategies for its dysregulation.

Genular Protein ID: 1668419499

Symbol: ACTN1_HUMAN

Name: Alpha-actinin-1

UniProtKB Accession Codes:

P12814 B3V8S3 B4DHH3 B7TY16 Q1HE25 Q9BTN1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 4 CORUM 1 CTD 1 CarbonylDB 1 ChEBI 5 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EMBL 12 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 37 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRIDE 1 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 7 RefSeq 3 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2780298

Title: The cDNA sequence of a human placental alpha-actinin.

PubMed ID: 2780298

DOI: 10.1093/nar/17.16.6725

PubMed ID: 2349951

Title: Cloning and chromosomal localization of the human cytoskeletal alpha-actinin gene reveals linkage to the beta-spectrin gene.

PubMed ID: 2349951

PubMed ID: 18353764

Title: Alternative splicing in colon, bladder, and prostate cancer identified by exon array analysis.

PubMed ID: 18353764

DOI: 10.1074/mcp.m700590-mcp200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2169343

Title: Expression of human alpha-actinin in human hepatocellular carcinoma.

PubMed ID: 2169343

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 8713105

Title: Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes.

PubMed ID: 8713105

DOI: 10.1006/bbrc.1996.1082

PubMed ID: 7750553

Title: Identification of the cytoskeletal protein alpha-actinin as a platelet thrombospondin-binding protein.

PubMed ID: 7750553

DOI: 10.1016/0014-5793(95)00362-d

PubMed ID: 10369880

Title: Myotilin, a novel sarcomeric protein with two Ig-like domains, is encoded by a candidate gene for limb-girdle muscular dystrophy.

PubMed ID: 10369880

DOI: 10.1093/hmg/8.7.1329

PubMed ID: 11114196

Title: Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.

PubMed ID: 11114196

DOI: 10.1073/pnas.260501097

PubMed ID: 11369769

Title: The cytoskeletal/non-muscle isoform of alpha-actinin is phosphorylated on its actin-binding domain by the focal adhesion kinase.

PubMed ID: 11369769

DOI: 10.1074/jbc.m101678200

PubMed ID: 12615977

Title: The lipoma preferred partner LPP interacts with alpha-actinin.

PubMed ID: 12615977

DOI: 10.1242/jcs.00309

PubMed ID: 16464232

Title: Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoring.

PubMed ID: 16464232

DOI: 10.1111/j.1471-4159.2006.03679.x

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22689882

Title: EWI-2 association with alpha-actinin regulates T cell immune synapses and HIV viral infection.

PubMed ID: 22689882

DOI: 10.4049/jimmunol.1103708

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 16698282

Title: Crystal structure of the actin-binding domain of alpha-actinin 1: evaluating two competing actin-binding models.

PubMed ID: 16698282

DOI: 10.1016/j.jsb.2006.01.013

PubMed ID: 23434115

Title: ACTN1 mutations cause congenital macrothrombocytopenia.

PubMed ID: 23434115

DOI: 10.1016/j.ajhg.2013.01.015

PubMed ID: 24069336

Title: A missense mutation in the alpha-actinin 1 gene (ACTN1) is the cause of autosomal dominant macrothrombocytopenia in a large French family.

PubMed ID: 24069336

DOI: 10.1371/journal.pone.0074728

Sequence Information:

  • Length: 892
  • Mass: 103058
  • Checksum: 6DA3E4D1A0289519
  • Sequence:
    • MDHYDSQQTN DYMQPEEDWD RDLLLDPAWE KQQRKTFTAW CNSHLRKAGT QIENIEEDFR 
DGLKLMLLLE VISGERLAKP ERGKMRVHKI SNVNKALDFI ASKGVKLVSI GAEEIVDGNV 
KMTLGMIWTI ILRFAIQDIS VEETSAKEGL LLWCQRKTAP YKNVNIQNFH ISWKDGLGFC 
ALIHRHRPEL IDYGKLRKDD PLTNLNTAFD VAEKYLDIPK MLDAEDIVGT ARPDEKAIMT 
YVSSFYHAFS GAQKAETAAN RICKVLAVNQ ENEQLMEDYE KLASDLLEWI RRTIPWLENR 
VPENTMHAMQ QKLEDFRDYR RLHKPPKVQE KCQLEINFNT LQTKLRLSNR PAFMPSEGRM 
VSDINNAWGC LEQVEKGYEE WLLNEIRRLE RLDHLAEKFR QKASIHEAWT DGKEAMLRQK 
DYETATLSEI KALLKKHEAF ESDLAAHQDR VEQIAAIAQE LNELDYYDSP SVNARCQKIC 
DQWDNLGALT QKRREALERT EKLLETIDQL YLEYAKRAAP FNNWMEGAME DLQDTFIVHT 
IEEIQGLTTA HEQFKATLPD ADKERLAILG IHNEVSKIVQ TYHVNMAGTN PYTTITPQEI 
NGKWDHVRQL VPRRDQALTE EHARQQHNER LRKQFGAQAN VIGPWIQTKM EEIGRISIEM 
HGTLEDQLSH LRQYEKSIVN YKPKIDQLEG DHQLIQEALI FDNKHTNYTM EHIRVGWEQL 
LTTIARTINE VENQILTRDA KGISQEQMNE FRASFNHFDR DHSGTLGPEE FKACLISLGY 
DIGNDPQGEA EFARIMSIVD PNRLGVVTFQ AFIDFMSRET ADTDTADQVM ASFKILAGDK 
NYITMDELRR ELPPDQAEYC IARMAPYTGP DSVPGALDYM SFSTALYGES DL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.