Details for: HDAC3
Associated with
Other Information
Genular Protein ID: 4223018309
Symbol: HDAC3_HUMAN
Name: Histone deacetylase 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9464271
Title: Differential display cloning of a novel human histone deacetylase (HDAC3) cDNA from PHA-activated immune cells.
PubMed ID: 9464271
PubMed ID: 9346952
Title: Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family.
PubMed ID: 9346952
PubMed ID: 9501169
Title: Characterization of a human RPD3 ortholog, HDAC3.
PubMed ID: 9501169
PubMed ID: 10051405
Title: Genomic organization and chromosomal localization of the human histone deacetylase 3 gene.
PubMed ID: 10051405
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15572445
Title: Human cytomegalovirus immediate-early 1 protein facilitates viral replication by antagonizing histone deacetylation.
PubMed ID: 15572445
PubMed ID: 11006275
Title: Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing.
PubMed ID: 11006275
PubMed ID: 10669754
Title: Sequestration and inhibition of Daxx-mediated transcriptional repression by PML.
PubMed ID: 10669754
PubMed ID: 10655483
Title: Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5.
PubMed ID: 10655483
PubMed ID: 10860984
Title: The histone deacetylase-3 complex contains nuclear receptor corepressors.
PubMed ID: 10860984
PubMed ID: 11466315
Title: Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo.
PubMed ID: 11466315
PubMed ID: 11533236
Title: ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain.
PubMed ID: 11533236
PubMed ID: 11861901
Title: Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain.
PubMed ID: 11861901
PubMed ID: 12032081
Title: The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase.
PubMed ID: 12032081
PubMed ID: 10809664
Title: A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness.
PubMed ID: 10809664
PubMed ID: 10944117
Title: Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3.
PubMed ID: 10944117
PubMed ID: 10898795
Title: BCoR, a novel corepressor involved in BCL-6 repression.
PubMed ID: 10898795
PubMed ID: 11931768
Title: The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2.
PubMed ID: 11931768
PubMed ID: 12628926
Title: Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1.
PubMed ID: 12628926
DOI: 10.1093/emboj/cdg120
PubMed ID: 14633989
Title: Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene.
PubMed ID: 14633989
DOI: 10.1093/emboj/cdg595
PubMed ID: 14525983
Title: DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.
PubMed ID: 14525983
PubMed ID: 15297880
Title: Regulation of human SRY subcellular distribution by its acetylation/deacetylation.
PubMed ID: 15297880
PubMed ID: 15927959
Title: Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein.
PubMed ID: 15927959
PubMed ID: 16569215
Title: INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases.
PubMed ID: 16569215
DOI: 10.1042/bj20051669
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18417529
Title: Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription.
PubMed ID: 18417529
DOI: 10.1677/joe-08-0001
PubMed ID: 18279852
Title: Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU.
PubMed ID: 18279852
PubMed ID: 19409814
Title: NKAP is a transcriptional repressor of notch signaling and is required for T cell development.
PubMed ID: 19409814
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21030595
Title: HDAC3 is negatively regulated by the nuclear protein DBC1.
PubMed ID: 21030595
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21914818
Title: A BEN-domain-containing protein associates with heterochromatin and represses transcription.
PubMed ID: 21914818
DOI: 10.1242/jcs.086603
PubMed ID: 21444723
Title: Acetylation of a conserved lysine residue in the ATP binding pocket of p38 augments its kinase activity during hypertrophy of cardiomyocytes.
PubMed ID: 21444723
DOI: 10.1128/mcb.01205-10
PubMed ID: 23911289
Title: A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.
PubMed ID: 23911289
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25190803
Title: Unspliced X-box-binding protein 1 (XBP1) protects endothelial cells from oxidative stress through interaction with histone deacetylase 3.
PubMed ID: 25190803
PubMed ID: 25301942
Title: Regulation of histone acetyltransferase TIP60 function by histone deacetylase 3.
PubMed ID: 25301942
PubMed ID: 28497810
Title: Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription.
PubMed ID: 28497810
DOI: 10.1038/cr.2017.68
PubMed ID: 28167758
Title: MicroRNA-10a is crucial for endothelial response to different flow patterns via interaction of retinoid acid receptors and histone deacetylases.
PubMed ID: 28167758
PubMed ID: 29192674
Title: Landscape of the regulatory elements for lysine 2-hydroxyisobutyrylation pathway.
PubMed ID: 29192674
DOI: 10.1038/cr.2017.149
PubMed ID: 32404892
Title: USP38 regulates the stemness and chemoresistance of human colorectal cancer via regulation of HDAC3.
PubMed ID: 32404892
PubMed ID: 34608293
Title: Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis.
PubMed ID: 34608293
Sequence Information:
- Length: 428
- Mass: 48848
- Checksum: 94485C1EBDCF5AD0
- Sequence:
MAKTVAYFYD PDVGNFHYGA GHPMKPHRLA LTHSLVLHYG LYKKMIVFKP YQASQHDMCR FHSEDYIDFL QRVSPTNMQG FTKSLNAFNV GDDCPVFPGL FEFCSRYTGA SLQGATQLNN KICDIAINWA GGLHHAKKFE ASGFCYVNDI VIGILELLKY HPRVLYIDID IHHGDGVQEA FYLTDRVMTV SFHKYGNYFF PGTGDMYEVG AESGRYYCLN VPLRDGIDDQ SYKHLFQPVI NQVVDFYQPT CIVLQCGADS LGCDRLGCFN LSIRGHGECV EYVKSFNIPL LVLGGGGYTV RNVARCWTYE TSLLVEEAIS EELPYSEYFE YFAPDFTLHP DVSTRIENQN SRQYLDQIRQ TIFENLKMLN HAPSVQIHDV PADLLTYDRT DEADAEERGP EENYSRPEAP NEFYDGDHDN DKESDVEI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.