Details for: PROM1

Gene ID: 8842

Symbol: PROM1

Ensembl ID: ENSG00000007062

Description: prominin 1

Associated with

Other Information

Genular Protein ID: 4220186972

Symbol: PROM1_HUMAN

Name: Prominin-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9389721

Title: A novel five-transmembrane hematopoietic stem cell antigen: isolation, characterization, and molecular cloning.

PubMed ID: 9389721

PubMed ID: 12042327

Title: AC133-2, a novel isoform of human AC133 stem cell antigen.

PubMed ID: 12042327

DOI: 10.1074/jbc.m202349200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9389720

Title: AC133, a novel marker for human hematopoietic stem and progenitor cells.

PubMed ID: 9389720

PubMed ID: 17874118

Title: Differential expression of prominin-1 (CD133) and prominin-2 in major cephalic exocrine glands of adult mice.

PubMed ID: 17874118

DOI: 10.1007/s00418-007-0334-2

PubMed ID: 17498271

Title: Nomenclature of prominin-1 (CD133) splice variants - an update.

PubMed ID: 17498271

DOI: 10.1111/j.1399-0039.2007.00825.x

PubMed ID: 18096722

Title: The stem cell marker prominin-1/CD133 on membrane particles in human cerebrospinal fluid offers novel approaches for studying central nervous system disease.

PubMed ID: 18096722

DOI: 10.1634/stemcells.2007-0639

PubMed ID: 19302789

Title: Release of extracellular membrane vesicles from microvilli of epithelial cells is enhanced by depleting membrane cholesterol.

PubMed ID: 19302789

DOI: 10.1016/j.febslet.2009.01.048

PubMed ID: 20818439

Title: CD133 suppresses neuroblastoma cell differentiation via signal pathway modification.

PubMed ID: 20818439

DOI: 10.1038/onc.2010.383

PubMed ID: 10587575

Title: A frameshift mutation in prominin (mouse)-like 1 causes human retinal degeneration.

PubMed ID: 10587575

DOI: 10.1093/hmg/9.1.27

PubMed ID: 17605048

Title: Severe retinitis pigmentosa mapped to 4p15 and associated with a novel mutation in the PROM1 gene.

PubMed ID: 17605048

DOI: 10.1007/s00439-007-0395-2

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24556617

Title: Post-translational regulation of CD133 by ATase1/ATase2-mediated lysine acetylation.

PubMed ID: 24556617

DOI: 10.1016/j.jmb.2014.02.012

PubMed ID: 18654668

Title: Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.

PubMed ID: 18654668

DOI: 10.1172/jci35891

PubMed ID: 35947379

Title: Dominant Cone Rod Dystrophy, Previously Assigned to a Missense Variant in RIMS1, Is Fully Explained by Co-Inheritance of a Dominant Allele of PROM1.

PubMed ID: 35947379

DOI: 10.1167/iovs.63.9.14

Sequence Information:

  • Length: 865
  • Mass: 97202
  • Checksum: D21CBC05ADB2DEDF
  • Sequence:
  • MALVLGSLLL LGLCGNSFSG GQPSSTDAPK AWNYELPATN YETQDSHKAG PIGILFELVH 
    IFLYVVQPRD FPEDTLRKFL QKAYESKIDY DKPETVILGL KIVYYEAGII LCCVLGLLFI 
    ILMPLVGYFF CMCRCCNKCG GEMHQRQKEN GPFLRKCFAI SLLVICIIIS IGIFYGFVAN 
    HQVRTRIKRS RKLADSNFKD LRTLLNETPE QIKYILAQYN TTKDKAFTDL NSINSVLGGG 
    ILDRLRPNII PVLDEIKSMA TAIKETKEAL ENMNSTLKSL HQQSTQLSSS LTSVKTSLRS 
    SLNDPLCLVH PSSETCNSIR LSLSQLNSNP ELRQLPPVDA ELDNVNNVLR TDLDGLVQQG 
    YQSLNDIPDR VQRQTTTVVA GIKRVLNSIG SDIDNVTQRL PIQDILSAFS VYVNNTESYI 
    HRNLPTLEEY DSYWWLGGLV ICSLLTLIVI FYYLGLLCGV CGYDRHATPT TRGCVSNTGG 
    VFLMVGVGLS FLFCWILMII VVLTFVFGAN VEKLICEPYT SKELFRVLDT PYLLNEDWEY 
    YLSGKLFNKS KMKLTFEQVY SDCKKNRGTY GTLHLQNSFN ISEHLNINEH TGSISSELES 
    LKVNLNIFLL GAAGRKNLQD FAACGIDRMN YDSYLAQTGK SPAGVNLLSF AYDLEAKANS 
    LPPGNLRNSL KRDAQTIKTI HQQRVLPIEQ SLSTLYQSVK ILQRTGNGLL ERVTRILASL 
    DFAQNFITNN TSSVIIEETK KYGRTIIGYF EHYLQWIEFS ISEKVASCKP VATALDTAVD 
    VFLCSYIIDP LNLFWFGIGK ATVFLLPALI FAVKLAKYYR RMDSEDVYDD VETIPMKNME 
    NGNNGYHKDH VYGIHNPVMT SPSQH

Genular Protein ID: 3355318844

Symbol: A0A0A0N0M1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 856
  • Mass: 96251
  • Checksum: DFF0B7AFE0A02582
  • Sequence:
  • MALVLGSLLL LGLCGNSFSG GQPSSTDAPK AWNYELPATN YETQDSHKAG PIGILFELVH 
    IFLYVVQPRD FPEDTLRKFL QKAYESKIDY DKIVYYEAGI ILCCVLGLLF IILMPLVGYF 
    FCMCRCCNKC GGEMHQRQKE NGPFLRKCFA ISLLVICIII SIGIFYGFVA NHQVRTRIKR 
    SRKLADSNFK DLRTLLNETP EQIKYILAQY NTTKDKAFTD LNSINSVLGG GILDRLRPNI 
    IPVLDEIKSM ATAIKETKEA LENMNSTLKS LHQQSTQLSS SLTSVKTSLR SSLNDPLCLV 
    HPSSETCNSI RLSLSQLNSN PELRQLPPVD AELDNVNNVL RTDLDGLVQQ GYQSLNDIPD 
    RVQRQTTTVV AGIKRVLNSI GSDIDNVTQR LPIQDILSAF SVYVNNTESY IHRNLPTLEE 
    YDSYWWLGGL VICSLLTLIV IFYYLGLLCG VCGYDRHATP TTRGCVSNTG GVFLMVGVGL 
    SFLFCWILMI IVVLTFVFGA NVEKLICEPY TSKELFRVLD TPYLLNEDWE YYLSGKLFNK 
    SKMKLTFEQV YSDCKKNRGT YGTLHLQNSF NISEHLNINE HTGSISSELE SLKVNLNIFL 
    LGAAGRKNLQ DFAACGIDRM NYDSYLAQTG KSPAGVNLLS FAYDLEAKAN SLPPGNLRNS 
    LKRDAQTIKT IHQQRVLPIE QSLSTLYQSV KILQRTGNGL LERVTRILAS LDFAQNFITN 
    NTSSVIIEET KKYGRTIIGY FEHYLQWIEF SISEKVASCK PVATALDTAV DVFLCSYIID 
    PLNLFWFGIG KATVFLLPAL IFAVKLAKYY RRMDSEDVYD DVETIPMKNM ENGNNGYHKD 
    HVYGIHNPVM TSPSQH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.