APLN | ENSG00000171388 | NCBI 8862

Details for: APLN

Gene ID: 8862

Symbol: APLN

Ensembl ID: ENSG00000171388

Description: apelin

Associated with

Class a/1 (rhodopsin-like receptors)
(R-HSA-373076)
G alpha (i) signalling events
(R-HSA-418594)
Gpcr downstream signalling
(R-HSA-388396)
Gpcr ligand binding
(R-HSA-500792)
Peptide ligand-binding receptors
(R-HSA-375276)
Signaling by gpcr
(R-HSA-372790)
Angiogenesis
(GO:0001525)
Apelin receptor binding
(GO:0031704)
Apelin receptor signaling pathway
(GO:0060183)
Coronary vasculature development
(GO:0060976)
Drinking behavior
(GO:0042756)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Gastrulation
(GO:0007369)
Hormone activity
(GO:0005179)
Immune response
(GO:0006955)
Lactation
(GO:0007595)
Negative regulation of blood pressure
(GO:0045776)
Negative regulation of fibroblast growth factor receptor signaling pathway
(GO:0040037)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of vascular associated smooth muscle cell proliferation
(GO:1904706)
Positive regulation of g protein-coupled receptor internalization
(GO:1904022)
Positive regulation of heart contraction
(GO:0045823)
Positive regulation of mirna transcription
(GO:1902895)
Positive regulation of vascular endothelial cell proliferation
(GO:1905564)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)

Other Information

Proteins

Apelin

Genular Protein ID: 1266089856

Symbol: APEL_HUMAN

Name: Apelin

UniProtKB Accession Codes:

Q9ULZ1 Q4VY08 Q8WU89

Database IDs:

Citations:

PubMed ID: 9792798

Title: Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor.

PubMed ID: 9792798

DOI: 10.1006/bbrc.1998.9489

PubMed ID: 10525157

Title: Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum.

PubMed ID: 10525157

DOI: 10.1016/s0167-4889(99)00114-7

PubMed ID: 10617103

Title: Characterization of apelin, the ligand for the APJ receptor.

PubMed ID: 10617103

DOI: 10.1046/j.1471-4159.2000.0740034.x

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11090199

Title: Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.

PubMed ID: 11090199

DOI: 10.1128/jvi.74.24.11972-11976.2000

Sequence Information:

Length: 77
Mass: 8569
Checksum: 41521E0DBE97BFDA
Sequence:

MNLRLCVQAL LLLWLSLTAV CGGSLMPLPD GNGLEDGNVR HLVQPRGSRN GPGPWQGGRR 
KFRRQRPRLS HKGPMPF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: APLN

Associated with

Other Information

Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. PubMed ID: 9792798

Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum. PubMed ID: 10525157

Characterization of apelin, the ligand for the APJ receptor. PubMed ID: 10617103

The DNA sequence of the human X chromosome. PubMed ID: 15772651

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334