Details for: PER2

Gene ID: 8864

Symbol: PER2

Ensembl ID: ENSG00000132326

Description: period circadian regulator 2

Associated with

Other Information

Genular Protein ID: 1100223064

Symbol: PER2_HUMAN

Name: Period circadian protein homolog 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11165242

Title: Human casein kinase Idelta phosphorylation of human circadian clock proteins period 1 and 2.

PubMed ID: 11165242

DOI: 10.1016/s0014-5793(00)02434-0

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 9427249

Title: Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei.

PubMed ID: 9427249

DOI: 10.1016/s0896-6273(00)80417-1

PubMed ID: 14750904

Title: Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts.

PubMed ID: 14750904

DOI: 10.1042/bj20031308

PubMed ID: 22274616

Title: PML regulates PER2 nuclear localization and circadian function.

PubMed ID: 22274616

DOI: 10.1038/emboj.2012.1

PubMed ID: 24202686

Title: Nucleolar localization and circadian regulation of Per2S, a novel splicing variant of the Period 2 gene.

PubMed ID: 24202686

DOI: 10.1007/s00018-013-1503-1

PubMed ID: 23303907

Title: Metabolism and the circadian clock converge.

PubMed ID: 23303907

DOI: 10.1152/physrev.00016.2012

PubMed ID: 23916625

Title: Molecular architecture of the mammalian circadian clock.

PubMed ID: 23916625

DOI: 10.1016/j.tcb.2013.07.002

PubMed ID: 30530698

Title: Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.

PubMed ID: 30530698

DOI: 10.1073/pnas.1816411115

PubMed ID: 31138685

Title: TIMELESS mutation alters phase responsiveness and causes advanced sleep phase.

PubMed ID: 31138685

DOI: 10.1073/pnas.1819110116

PubMed ID: 11232563

Title: An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.

PubMed ID: 11232563

DOI: 10.1126/science.1057499

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 1255
  • Mass: 136579
  • Checksum: 2AEF2C6BD4B6CBB0
  • Sequence:
  • MNGYAEFPPS PSNPTKEPVE PQPSQVPLQE DVDMSSGSSG HETNENCSTG RDSQGSDCDD 
    SGKELGMLVE PPDARQSPDT FSLMMAKSEH NPSTSGCSSD QSSKVDTHKE LIKTLKELKV 
    HLPADKKAKG KASTLATLKY ALRSVKQVKA NEEYYQLLMS SEGHPCGADV PSYTVEEMES 
    VTSEHIVKNA DMFAVAVSLV SGKILYISDQ VASIFHCKRD AFSDAKFVEF LAPHDVGVFH 
    SFTSPYKLPL WSMCSGADSF TQECMEEKSF FCRVSVRKSH ENEIRYHPFR MTPYLVKVRD 
    QQGAESQLCC LLLAERVHSG YEAPRIPPEK RIFTTTHTPN CLFQDVDERA VPLLGYLPQD 
    LIETPVLVQL HPSDRPLMLA IHKKILQSGG QPFDYSPIRF RARNGEYITL DTSWSSFINP 
    WSRKISFIIG RHKVRVGPLN EDVFAAHPCT EEKALHPSIQ ELTEQIHRLL LQPVPHSGSS 
    GYGSLGSNGS HEHLMSQTSS SDSNGHEDSR RRRAEICKNG NKTKNRSHYS HESGEQKKKS 
    VTEMQTNPPA EKKAVPAMEK DSLGVSFPEE LACKNQPTCS YQQISCLDSV IRYLESCNEA 
    ATLKRKCEFP ANVPALRSSD KRKATVSPGP HAGEAEPPSR VNSRTGVGTH LTSLALPGKA 
    ESVASLTSQC SYSSTIVHVG DKKPQPELEM VEDAASGPES LDCLAGPALA CGLSQEKEPF 
    KKLGLTKEVL AAHTQKEEQS FLQKFKEIRK LSIFQSHCHY YLQERSKGQP SERTAPGLRN 
    TSGIDSPWKK TGKNRKLKSK RVKPRDSSES TGSGGPVSAR PPLVGLNATA WSPSDTSQSS 
    CPAVPFPAPV PAAYSLPVFP APGTVAAPPA PPHASFTVPA VPVDLQHQFA VQPPPFPAPL 
    APVMAFMLPS YSFPSGTPNL PQAFFPSQPQ FPSHPTLTSE MASASQPEFP SRTSIPRQPC 
    ACPATRATPP SAMGRASPPL FQSRSSSPLQ LNLLQLEEAP EGGTGAMGTT GATETAAVGA 
    DCKPGTSRDQ QPKAPLTRDE PSDTQNSDAL STSSGLLNLL LNEDLCSASG SAASESLGSG 
    SLGCDASPSG AGSSDTSHTS KYFGSIDSSE NNHKAKMNTG MEESEHFIKC VLQDPIWLLM 
    ADADSSVMMT YQLPSRNLEA VLKEDREKLK LLQKLQPRFT ESQKQELREV HQWMQTGGLP 
    AAIDVAECVY CENKEKGNIC IPYEEDIPSL GLSEVSDTKE DENGSPLNHR IEEQT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.