ST3GAL5 | ENSG00000115525 | NCBI 8869

Details for: ST3GAL5

Gene ID: 8869

Symbol: ST3GAL5

Ensembl ID: ENSG00000115525

Description: ST3 beta-galactoside alpha-2,3-sialyltransferase 5

Associated with

Asparagine n-linked glycosylation
(R-HSA-446203)
Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
(R-HSA-446193)
Glycosphingolipid biosynthesis
(R-HSA-9840309)
Glycosphingolipid metabolism
(R-HSA-1660662)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Sialic acid metabolism
(R-HSA-4085001)
Sphingolipid metabolism
(R-HSA-428157)
Synthesis of substrates in n-glycan biosythesis
(R-HSA-446219)
Beta-galactoside (cmp) alpha-2,3-sialyltransferase activity
(GO:0003836)
Ganglioside biosynthetic process
(GO:0001574)
Glycosphingolipid biosynthetic process
(GO:0006688)
Golgi membrane
(GO:0000139)
Lactosylceramide alpha-2,3-sialyltransferase activity
(GO:0047291)
Membrane
(GO:0016020)
Protein glycosylation
(GO:0006486)
Sialyltransferase activity
(GO:0008373)

Other Information

Proteins

Lactosylceramide alpha-2,3-sialyltransferase

Genular Protein ID: 1696517156

Symbol: SIAT9_HUMAN

Name: Lactosylceramide alpha-2,3-sialyltransferase

UniProtKB Accession Codes:

Q9UNP4 B3KM82 D6W5L9 O94902 Q53QU1 Q6NZX4 Q6YFL1

Database IDs:

Citations:

PubMed ID: 9822625

Title: Expression cloning and functional characterization of human cDNA for ganglioside GM3 synthase.

PubMed ID: 9822625

DOI: 10.1074/jbc.273.48.31652

PubMed ID: 16934889

Title: Human GM3 synthase: a new mRNA variant encodes an NH2-terminal extended form of the protein.

PubMed ID: 16934889

DOI: 10.1016/j.bbaexp.2006.07.001

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15502825

Title: Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase.

PubMed ID: 15502825

DOI: 10.1038/ng1460

Sequence Information:

Length: 418
Mass: 47990
Checksum: B423540B31C27A8A
Sequence:

MRTKAAGCAE RRPLQPRTEA AAAPAGRAMP SEYTYVKLRS DCSRPSLQWY TRAQSKMRRP 
SLLLKDILKC TLLVFGVWIL YILKLNYTTE ECDMKKMHYV DPDHVKRAQK YAQQVLQKEC 
RPKFAKTSMA LLFEHRYSVD LLPFVQKAPK DSEAESKYDP PFGFRKFSSK VQTLLELLPE 
HDLPEHLKAK TCRRCVVIGS GGILHGLELG HTLNQFDVVI RLNSAPVEGY SEHVGNKTTI 
RMTYPEGAPL SDLEYYSNDL FVAVLFKSVD FNWLQAMVKK ETLPFWVRLF FWKQVAEKIP 
LQPKHFRILN PVIIKETAFD ILQYSEPQSR FWGRDKNVPT IGVIAVVLAT HLCDEVSLAG 
FGYDLNQPRT PLHYFDSQCM AAMNFQTMHN VTTETKFLLK LVKEGVVKDL SGGIDREF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ST3GAL5

Associated with

Other Information

Expression cloning and functional characterization of human cDNA for ganglioside GM3 synthase. PubMed ID: 9822625

Human GM3 synthase: a new mRNA variant encodes an NH2-terminal extended form of the protein. PubMed ID: 16934889

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Generation and annotation of the DNA sequences of human chromosomes 2 and 4. PubMed ID: 15815621

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase. PubMed ID: 15502825