Details for: CCKBR
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: colon endothelial cell (CL1001572)
Fold Change: 5.5423
Cell Significance Index: 4.2300 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 3.6200
Cell Significance Index: 61.8800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.3376
Cell Significance Index: 38.5400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 1.0457
Cell Significance Index: 26.1400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4755
Cell Significance Index: 21.5600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4160
Cell Significance Index: 41.1500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.4097
Cell Significance Index: 82.1900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2944
Cell Significance Index: 56.0400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2481
Cell Significance Index: 223.9800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2161
Cell Significance Index: 35.1500 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.1708
Cell Significance Index: 4.4900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.1599
Cell Significance Index: 2.2900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1330
Cell Significance Index: 47.7200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0922
Cell Significance Index: 10.0300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0503
Cell Significance Index: 34.7900 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.0503
Cell Significance Index: 0.6500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0306
Cell Significance Index: 13.5200 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.0127
Cell Significance Index: 0.1600 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.0092
Cell Significance Index: 0.2300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0049
Cell Significance Index: 0.8400 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.0032
Cell Significance Index: 0.0700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0020
Cell Significance Index: -0.0700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0048
Cell Significance Index: -9.0100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0065
Cell Significance Index: -8.7900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0068
Cell Significance Index: -12.5800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0080
Cell Significance Index: -12.2400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0102
Cell Significance Index: -7.5600 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.0107
Cell Significance Index: -0.2600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0123
Cell Significance Index: -8.9900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0138
Cell Significance Index: -0.3000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0142
Cell Significance Index: -9.0400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0146
Cell Significance Index: -0.2500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0157
Cell Significance Index: -8.8600 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0157
Cell Significance Index: -8.5700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0166
Cell Significance Index: -1.0200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0199
Cell Significance Index: -12.4000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0217
Cell Significance Index: -9.8400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0269
Cell Significance Index: -7.7300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0303
Cell Significance Index: -0.6500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0336
Cell Significance Index: -0.9400 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0352
Cell Significance Index: -0.7300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0400
Cell Significance Index: -2.6900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0424
Cell Significance Index: -6.1700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0461
Cell Significance Index: -9.1400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0466
Cell Significance Index: -8.4000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0492
Cell Significance Index: -10.3600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0505
Cell Significance Index: -5.8900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0605
Cell Significance Index: -3.7200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0644
Cell Significance Index: -4.4600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0720
Cell Significance Index: -8.2500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0720
Cell Significance Index: -9.8900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0735
Cell Significance Index: -9.0400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0765
Cell Significance Index: -2.4500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0913
Cell Significance Index: -9.5100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0928
Cell Significance Index: -9.4800 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.0964
Cell Significance Index: -1.3700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1009
Cell Significance Index: -2.8800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1022
Cell Significance Index: -4.5200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1081
Cell Significance Index: -2.7800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1086
Cell Significance Index: -3.4600 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.1124
Cell Significance Index: -1.5000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1142
Cell Significance Index: -3.0600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1240
Cell Significance Index: -3.3800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1284
Cell Significance Index: -8.0900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1326
Cell Significance Index: -5.0200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1346
Cell Significance Index: -10.3300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.1369
Cell Significance Index: -8.2200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1456
Cell Significance Index: -5.1000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1542
Cell Significance Index: -5.0500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1546
Cell Significance Index: -3.2400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.1631
Cell Significance Index: -1.8500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1674
Cell Significance Index: -8.7900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1687
Cell Significance Index: -3.5800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1691
Cell Significance Index: -9.4900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1739
Cell Significance Index: -9.0600 - Cell Name: neuron (CL0000540)
Fold Change: -0.1825
Cell Significance Index: -1.7300 - Cell Name: tendon cell (CL0000388)
Fold Change: -0.2015
Cell Significance Index: -2.7400 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.2048
Cell Significance Index: -1.3900 - Cell Name: peptic cell (CL0000155)
Fold Change: -0.2076
Cell Significance Index: -1.8500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2147
Cell Significance Index: -10.0900 - Cell Name: stromal cell of endometrium (CL0002255)
Fold Change: -0.2151
Cell Significance Index: -3.0600 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: -0.2206
Cell Significance Index: -3.0500 - Cell Name: fast muscle cell (CL0000190)
Fold Change: -0.2298
Cell Significance Index: -3.0100 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2329
Cell Significance Index: -11.7700 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2342
Cell Significance Index: -4.5700 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.2402
Cell Significance Index: -5.1900 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.2437
Cell Significance Index: -6.2100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.2498
Cell Significance Index: -4.9400 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.2598
Cell Significance Index: -2.8300 - Cell Name: megakaryocyte (CL0000556)
Fold Change: -0.2760
Cell Significance Index: -4.4700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2969
Cell Significance Index: -7.1200 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.3003
Cell Significance Index: -7.4900 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.3038
Cell Significance Index: -6.3400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3073
Cell Significance Index: -9.0500 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: -0.3084
Cell Significance Index: -3.4500 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.3146
Cell Significance Index: -3.4200 - Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
Fold Change: -0.3170
Cell Significance Index: -1.6600 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: -0.3179
Cell Significance Index: -3.4700 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.3193
Cell Significance Index: -10.1000 - Cell Name: CD141-positive myeloid dendritic cell (CL0002394)
Fold Change: -0.3200
Cell Significance Index: -3.4600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2577243348
Symbol: GASR_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1280419
Title: Molecular cloning of the human brain and gastric cholecystokinin receptor: structure, functional expression and chromosomal localization.
PubMed ID: 1280419
PubMed ID: 7681836
Title: The human brain cholecystokinin-B/gastrin receptor. Cloning and characterization.
PubMed ID: 7681836
PubMed ID: 8349705
Title: Functional characterization of a human brain cholecystokinin-B receptor. A trophic effect of cholecystokinin and gastrin.
PubMed ID: 8349705
PubMed ID: 8415658
Title: The human gastrin/cholecystokinin type B receptor gene: alternative splice donor site in exon 4 generates two variant mRNAs.
PubMed ID: 8415658
PubMed ID: 8185170
Title: Cholecystokinin stimulates Ca2+ mobilization and clonal growth in small cell lung cancer through CCKA and CCKB/gastrin receptors.
PubMed ID: 8185170
PubMed ID: 7848914
Title: Functional characterization of two cholecystokinin-B/gastrin receptor isoforms: a preferential splice donor site in the human receptor gene.
PubMed ID: 7848914
PubMed ID: 7887934
Title: A truncated isoform of human CCK-B/gastrin receptor generated by alternative usage of a novel exon.
PubMed ID: 7887934
PubMed ID: 10913157
Title: Human colorectal cancers express a constitutively active cholecystokinin-B/gastrin receptor that stimulates cell growth.
PubMed ID: 10913157
PubMed ID: 11495676
Title: Identification of CCK-B/gastrin receptor splice variants in human peripheral blood mononuclear cells.
PubMed ID: 11495676
PubMed ID: 12429993
Title: Characterization of the CCK-C (cancer) receptor in human pancreatic cancer.
PubMed ID: 12429993
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9872672
Title: An 84-kilobase physical map and repeat polymorphisms of the gastrin/cholecystokinin brain receptor region at the junction of chromosome segments 11p15.4 and 15.5.
PubMed ID: 9872672
PubMed ID: 8221657
Title: CCKA and CCKB receptors are expressed in small cell lung cancer lines and mediate Ca2+ mobilization and clonal growth.
PubMed ID: 8221657
PubMed ID: 8222757
Title: Localization of the human cholecystokinin-B/gastrin receptor gene (CCKBR) to chromosome 11p15.5-->p15.4 by fluorescence in situ hybridization.
PubMed ID: 8222757
DOI: 10.1159/000133628
PubMed ID: 11926817
Title: Intermolecular interactions between cholecystokinin-8 and the third extracellular loop of the cholecystokinin-2 receptor.
PubMed ID: 11926817
DOI: 10.1021/bi0160009
Sequence Information:
- Length: 447
- Mass: 48419
- Checksum: BAEEFAD4C1F85915
- Sequence:
MELLKLNRSV QGTGPGPGAS LCRPGAPLLN SSSVGNLSCE PPRIRGAGTR ELELAIRITL YAVIFLMSVG GNMLIIVVLG LSRRLRTVTN AFLLSLAVSD LLLAVACMPF TLLPNLMGTF IFGTVICKAV SYLMGVSVSV STLSLVAIAL ERYSAICRPL QARVWQTRSH AARVIVATWL LSGLLMVPYP VYTVVQPVGP RVLQCVHRWP SARVRQTWSV LLLLLLFFIP GVVMAVAYGL ISRELYLGLR FDGDSDSDSQ SRVRNQGGLP GAVHQNGRCR PETGAVGEDS DGCYVQLPRS RPALELTALT APGPGSGSRP TQAKLLAKKR VVRMLLVIVV LFFLCWLPVY SANTWRAFDG PGAHRALSGA PISFIHLLSY ASACVNPLVY CFMHRRFRQA CLETCARCCP RPPRARPRAL PDEDPPTPSI ASLSRLSYTT ISTLGPG
Genular Protein ID: 3781845939
Symbol: E9PIC8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
Sequence Information:
- Length: 363
- Mass: 39286
- Checksum: 872A069F630A64E6
- Sequence:
MELLKLNRSV QGTGPGPGAS LCRPGAPLLN SSSVGNLSCE PPRIRGAGTR GVSVSVSTLS LVAIALERYS AICRPLQARV WQTRSHAARV IVATWLLSGL LMVPYPVYTV VQPVGPRVLQ CVHRWPSARV RQTWSVLLLL LLFFIPGVVM AVAYGLISRE LYLGLRFDGD SDSDSQSRVR NQGGLPGAVH QNGRCRPETG AVGEDSDGCY VQLPRSRPAL ELTALTAPGP GSGSRPTQAK LLAKKRVVRM LLVIVVLFFL CWLPVYSANT WRAFDGPGAH RALSGAPISF IHLLSYASAC VNPLVYCFMH RRFRQACLET CARCCPRPPR ARPRALPDED PPTPSIASLS RLSYTTISTL GPG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.