Details for: ARHGEF7

Gene ID: 8874

Symbol: ARHGEF7

Ensembl ID: ENSG00000102606

Description: Rho guanine nucleotide exchange factor 7

Associated with

Other Information

Genular Protein ID: 1624258107

Symbol: ARHG7_HUMAN

Name: Rho guanine nucleotide exchange factor 7

UniProtKB Accession Codes:

Q14155 B1ALK6 B1ALK8 Q3LIA4 Q5W9H0 Q6P9G3 Q6PII2 Q86W63 Q8N3M1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 4 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EPD 1 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 28 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 4 PRINTS 1 PRO 1 PROSITE 5 PROSITE-ProRule 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 12 RefSeq 12 SAM 1 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8590280

Title: Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 8590280

DOI: 10.1093/dnares/2.4.167

PubMed ID: 9726964

Title: A novel regulator of p21-activated kinases.

PubMed ID: 9726964

DOI: 10.1074/jbc.273.37.23633

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15491607

Title: Alternative splice variants encoding unstable protein domains exist in the human brain.

PubMed ID: 15491607

DOI: 10.1016/j.jmb.2004.09.028

PubMed ID: 12880961

Title: Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma.

PubMed ID: 12880961

DOI: 10.1016/s0304-3835(03)00085-5

PubMed ID: 15182672

Title: Mammalian Scribble forms a tight complex with the betaPIX exchange factor.

PubMed ID: 15182672

DOI: 10.1016/j.cub.2004.05.051

PubMed ID: 16329988

Title: Molecular interaction of NADPH oxidase 1 with betaPix and Nox Organizer 1.

PubMed ID: 16329988

DOI: 10.1016/j.bbrc.2005.11.108

PubMed ID: 19041750

Title: Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma.

PubMed ID: 19041750

DOI: 10.1016/j.cell.2008.09.045

PubMed ID: 18716323

Title: Scrib regulates PAK activity during the cell migration process.

PubMed ID: 18716323

DOI: 10.1093/hmg/ddn248

PubMed ID: 19118189

Title: Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.

PubMed ID: 19118189

DOI: 10.1523/jneurosci.3112-08.2008

PubMed ID: 18184567

Title: Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/betaPIX signaling complex.

PubMed ID: 18184567

DOI: 10.1016/j.neuron.2007.11.016

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21926430

Title: Sorting nexin 27 protein regulates trafficking of a p21-activated kinase (PAK) interacting exchange factor (beta-Pix)-G protein-coupled receptor kinase interacting protein (GIT) complex via a PDZ domain interaction.

PubMed ID: 21926430

DOI: 10.1074/jbc.m111.260802

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23285027

Title: Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis.

PubMed ID: 23285027

DOI: 10.1371/journal.pone.0052401

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 9846881

Title: Structure and mutagenesis of the Dbl homology domain.

PubMed ID: 9846881

DOI: 10.1038/4209

PubMed ID: 16101281

Title: Structural analysis of the SH3 domain of beta-PIX and its interaction with alpha-p21 activated kinase (PAK).

PubMed ID: 16101281

DOI: 10.1021/bi050374a

PubMed ID: 21248752

Title: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

PubMed ID: 21248752

DOI: 10.1038/nature09639

Sequence Information:

  • Length: 803
  • Mass: 90012
  • Checksum: 613EBA839E6FDBFD
  • Sequence:
    • MNSAEQTVTW LITLGVLESP KKTISDPEGF LQASLKDGVV LCRLLERLLP GTIEKVYPEP 
RSESECLSNI REFLRGCGAS LRLELLFPPS QPPQHLVTTI LLSASTFDAN DLYQGQNFNK 
VLSSLVTLNK VTADIGLGSD SVCARPSSHR IKSFDSLGSQ SLHTRTSKLF QGQYRSLDMT 
DNSNNQLVVR AKFNFQQTNE DELSFSKGDV IHVTRVEEGG WWEGTLNGRT GWFPSNYVRE 
VKASEKPVSP KSGTLKSPPK GFDTTAINKS YYNVVLQNIL ETENEYSKEL QTVLSTYLRP 
LQTSEKLSSA NISYLMGNLE EICSFQQMLV QSLEECTKLP EAQQRVGGCF LNLMPQMKTL 
YLTYCANHPS AVNVLTEHSE ELGEFMETKG ASSPGILVLT TGLSKPFMRL DKYPTLLKEL 
ERHMEDYHTD RQDIQKSMAA FKNLSAQCQE VRKRKELELQ ILTEAIRNWE GDDIKTLGNV 
TYMSQVLIQC AGSEEKNERY LLLFPNVLLM LSASPRMSGF IYQGKLPTTG MTITKLEDSE 
NHRNAFEISG SMIERILVSC NNQQDLQEWV EHLQKQTKVT SVGNPTIKPH SVPSHTLPSH 
PVTPSSKHAD SKPAPLTPAY HTLPHPSHHG TPHTTINWGP LEPPKTPKPW SLSCLRPAPP 
LRPSAALCYK EDLSKSPKTM KKLLPKRKPE RKPSDEEFAS RKSTAALEED AQILKVIEAY 
CTSAKTRQTL NSTWQGTDLM HNHVLADDDQ PSLDSLGRRS SLSRLEPSDL SEDSDYDSIW 
TAHSYRMGST SRKSCCSYIS HQN

Genular Protein ID: 1566988100

Symbol: A0A8V8TQ72_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8V8TQ72

Database IDs:

ARBA 3 CDD 4 CTD 1 EMBL 5 EPD 1 Ensembl 2 GO 3 Gene3D 5 GeneTree 1 HGNC 1 InterPro 12 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 9 PROSITE-ProRule 1 Pfam 7 Proteomes 2 RefSeq 1 SAM 2 SMART 4 SUPFAM 4

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

Sequence Information:

  • Length: 803
  • Mass: 90461
  • Checksum: 645E1399E1EC73C9
  • Sequence:
    • MNSAEQTVTW LITLGVLESP KKTISDPEGF LQASLKDGVV LCRLLERLLP GTIEKVYPEP 
RSESECLSNI REFLRGCGAS LRLETFDAND LYQGQNFNKV LSSLVTLNKV TADIGLGSDS 
VCARPSSHRI KSFDSLGSQS LHTRTSKLFQ GQYRSLDMTD NSNNQLVVRA KFNFQQTNED 
ELSFSKGDVI HVTRVEEGGW WEGTLNGRTG WFPSNYVREV KASEKPVSPK SGTLKSPPKG 
FDTTAINKSY YNVVLQNILE TENEYSKELQ TVLSTYLRPL QTSEKLSSAN ISYLMGNLEE 
ICSFQQMLVQ SLEECTKLPE AQQRVGGCFL NLMPQMKTLY LTYCANHPSA VNVLTEHSEE 
LGEFMETKGA SSPGILVLTT GLSKPFMRLD KYPTLLKELE RHMEDYHTDR QDIQKSMAAF 
KNLSAQCQEV RKRKELELQI LTEAIRNWEG DDIKTLGNVT YMSQVLIQCA GSEEKNERYL 
LLFPNVLLML SASPRMSGFI YQGKLPTTGM TITKLEDSEN HRNAFEISGS MIERILVSCN 
NQQDLQEWVE HLQKQTKVTS VGNPTIKPHS VPSHTLPSHP VTPSSKHADS KPAPLTPAYH 
TLPHPSHHGT PHTTINWGPL EPPKTPKPWS LSCLRPAPPL RPSAALCYKE DLSKSPKTMK 
KLLPKRKPER KPSDEEFASR KSTAALEEDA QILKVIEAYC TSAKTRQTLN SSSRKESAPQ 
VLLPEEEKII VEETKSNGQT VIEEKSLVDT VYALKDEVQE LRQDNKKMKK SLEEEQRARK 
DLEKLVRKVL KNMNDPAWDE TNL

Genular Protein ID: 2424233087

Symbol: E9PDQ5_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PDQ5

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 547
  • Mass: 61630
  • Checksum: 0F7899CC13022419
  • Sequence:
    • MGSCSSQSVQ KTRRGRKVVL QNILETENEY SKELQTVLST YLRPLQTSEK LSSANISYLM 
GNLEEICSFQ QMLVQSLEEC TKLPEAQQRV GGCFLNLMPQ MKTLYLTYCA NHPSAVNVLT 
EHSEELGEFM ETKGASSPGI LVLTTGLSKP FMRLDKYPTL LKELERHMED YHTDRQDIQK 
SMAAFKNLSA QCQEVRKRKE LELQILTEAI RNWEGDDIKT LGNVTYMSQV LIQCAGSEEK 
NERYLLLFPN VLLMLSASPR MSGFIYQGKL PTTGMTITKL EDSENHRNAF EISGSMIERI 
LVSCNNQQDL QEWVEHLQKQ TKVTSVGNPT IKPHSVPSHT LPSHPVTPSS KHADSKPAPL 
TPAYHTLPHP SHHGTPHTTI NWGPLEPPKT PKPWSLSCLR PAPPLRPSAA LCYKEDLSKS 
PKTMKKLLPK RKPERKPSDE EFASRKSTAA LEEDAQILKV IEAYCTSAKT RQTLNSTWQG 
TDLMHNHVLA DDDQPSLDSL GRRSSLSRLE PSDLSEDSDY DSIWTAHSYR MGSTSRKSCC 
SYISHQN

Genular Protein ID: 581883784

Symbol: Q5W9H1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5W9H1

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 4 GenomeRNAi 1 InterPro 11 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 6 RefSeq 3 SAM 2 SMART 4 SUPFAM 4

Citations:

PubMed ID: 15491607

Title: Alternative splice variants encoding unstable protein domains exist in the human brain.

PubMed ID: 15491607

DOI: 10.1016/j.jmb.2004.09.028

Sequence Information:

  • Length: 691
  • Mass: 77790
  • Checksum: 79570CF1CA88AFEE
  • Sequence:
    • IPPSKPLRGS SLWGCWSRPK KTISDPEGFL QASLKDGVVL CRLLERLLPG TIEKVYPEPR 
SESECLSNIR EFLRGCGASL RLETFDANDL YQGQNFNKVL SSLVTLNKVT ADIGLGSDSV 
CARPSSHRIK SFDSLGSQSL HTRTSKLFQG QYRSLDMTDN SNNQLVVRAK FNFQQTNEDE 
LSFSKGDVIH VTRVEEGGWW EGTLNGRTGW FPSNYVREVK ASEKPVSPKS GTLKSPPKGF 
DTTAINKSYY NVVLQNILET ENEYSKELQT VLSTYLRPLQ TSEKLSSANI SYLMGNLEEI 
CSFQQMLVQS LEECTKLPEA QQRVGGCFLN LMPQMKTLYL TYCANHPSAV NVLTEHSEEL 
GEFMETKGAS SPGILVLTTG LSKPFMRLDK YPTLLKELER HMEDYHTDRQ DIQKSMAAFK 
NLSAQCQEVR KRKELELQIL TEAIRNWEGD DIKTLGNVTY MSQVLIQCAG SEEKNERYLL 
LFPNVLLMLS ASPRMSGFIY QGKLPTTGMT ITKLEDSENH RNAFEISGSM IERILVSCNN 
QQDLQEWVEH LQKQTKVTSV GNPTIKPHSV PSHTLPSHPV TPSSKHADSK PAPLTPAYHT 
LPHPSHHGTP HTTINWGPLE PPKTPKPWSL SCLRPAPPLR PSAALCYKED LSKSPKTMKK 
LLPKRKPERK PSMRSSRPGK AQLLWKKMLR F

Genular Protein ID: 1515924751

Symbol: B7Z6G2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z6G2

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 5 GenomeRNAi 1 IntAct 1 InterPro 11 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 6 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 721
  • Mass: 81404
  • Checksum: 4051F1413D21F0E2
  • Sequence:
    • MKTFDANDLY QGQNFNKVLS SLVTLNKVTA DIGLGSDSVC ARPSSHRIKS FDSLGSQSLH 
TRTSKLFQGQ YRSLDMTDNS NNQLVVRAKF NFQQTNEDEL SFSKGDVIHV TRVEEGGWWE 
GTLNGRTGWF PSNYVREVKA SEKPVSPKSG TLKSPPKGFD TTAINKSYYN VVLQNILETE 
NEYSKELQTV LSTYLRPLQT SEKLSSANIS YLMGNLEEIC SFQQMLVQSL EECTKLPEAQ 
QRVGGCFLNL MPQMKTLYLT YCANHPSAVN VLTEHSEELG EFMETKGASS PGILVLTTGL 
SKPFMRLDKY PTLLKELERH MEDYHTDRQD IQKSMAAFKN LSAQCQEVRK RKELELQILT 
EAIRNWEGDD IKTLGNVTYM SQVLIQCAGS EEKNERYLLL FPNVLLMLSA SPRMSGFIYQ 
GKLPTTGMTI TKLEDSENHR NAFEISGSMI ERILVSCNNQ QDLQEWVEHL QKQTKVTSVG 
NPTIKPHSVP SHTLPSHPVT PSSKHADSKP APLTPAYHTL PHPSHHGTPH TTINWGPLEP 
PKTPKPWSLS CLRPAPPLRP SAALCYKEDL SKSPKTMKKL LPKRKPERKP SDEEFASRKS 
TAALEEDAQI LKVIEAYCTS AKTRQTLNSS SRKESAPQVL LPEEEKIIVE ETKSNGQTVI 
EEKSLVDTVY ALKDEVQELR QDNKKMKKSL EEEQRARKDL EKLVRKVLKN MNDPAWDETN 
L

Genular Protein ID: 2634998335

Symbol: B7Z344_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z344

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 GenomeRNAi 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 2 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 547
  • Mass: 61597
  • Checksum: 34EA0378B4B4C359
  • Sequence:
    • MGSCSSQSVQ KTRRGRKVVL QNILETENEY SKELQTVLST YLRPLQTSEK LSSANISYLM 
GNLEEICSFQ QMLVQSLEEC TKLPEAQQRV GGCFLNLMPQ MKTLYLTYCA NHPSAVNVLT 
EHSEELGEFM ETKGASSPGI LVLTTGLSKP FMRLDKYPTL LKELERHMED YHTDRQDIQK 
SIAAFKNLSA QCQEVRKRKE LELQILTEAI RNWEGDDIKT LGNVTYMSQV LIQCAGSEEK 
NERYLLLFPN VLLMLSASPR MSGFIYQGKL PTTGMTITKL EDSENHRNAF EISGSMIERI 
LVSCNNQQDL QEWVEHLQKQ TKVTSVGNPT IKPHSVPSHT LPSHPVTPSS KHADSKPAPL 
TPAYHTLPHP SHHGTPHTTI NWGPLEPPKT PKPWSLSCLR PAPPLRPSAA LCYKEDLSKS 
PKTMKKLLPK RKPERKPSDE EFASRKSTAA LEEDALILKV IEAYCTSAKT RQTLNSTWQG 
TDLMHNHVLA DDDQPSLDSL GRRSSLSRLE PSDLSEDSDY DSIWTAHSYR MGSTSRKSCC 
SYISHQN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.