MTMR3 | ENSG00000100330 | NCBI 8897

Details for: MTMR3

Gene ID: 8897

Symbol: MTMR3

Ensembl ID: ENSG00000100330

Description: myotubularin related protein 3

Associated with

Autophagy
(R-HSA-9612973)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Phospholipid metabolism
(R-HSA-1483257)
Pi metabolism
(R-HSA-1483255)
Synthesis of pips at the plasma membrane
(R-HSA-1660499)
Cellular response to glucose starvation
(GO:0042149)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Macroautophagy
(GO:0016236)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
(GO:0052629)
Phosphatidylinositol-3-phosphate phosphatase activity
(GO:0004438)
Phosphatidylinositol 5-phosphate metabolic process
(GO:1904562)
Phosphatidylinositol biosynthetic process
(GO:0006661)
Phosphatidylinositol dephosphorylation
(GO:0046856)
Protein binding
(GO:0005515)
Protein dephosphorylation
(GO:0006470)
Protein phosphatase binding
(GO:0019903)
Protein serine/threonine phosphatase activity
(GO:0004722)
Protein tyrosine/serine/threonine phosphatase activity
(GO:0008138)
Protein tyrosine phosphatase activity
(GO:0004725)
Regulation of autophagosome assembly
(GO:2000785)
Regulation of autophagy
(GO:0010506)
Regulation of phosphatidylinositol dephosphorylation
(GO:0060304)

Other Information

Proteins

FYVE domain-containing dual specificity protein phosphatase 1

Genular Protein ID: 1831685636

Symbol: MTMR3_HUMAN

Name: FYVE domain-containing dual specificity protein phosphatase 1

UniProtKB Accession Codes:

Q13615 A5PL26 A7MD32 Q9NYN5 Q9NYN6 Q9UDX6 Q9UEG3

Database IDs:

Citations:

PubMed ID: 10733931

Title: FYVE-DSP1, a dual-specificity protein phosphatase containing an FYVE domain.

PubMed ID: 10733931

DOI: 10.1006/bbrc.2000.2417

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9736772

Title: Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.

PubMed ID: 9736772

DOI: 10.1093/hmg/7.11.1703

PubMed ID: 8640223

Title: A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast.

PubMed ID: 8640223

DOI: 10.1038/ng0696-175

PubMed ID: 11676921

Title: Characterization of MTMR3. an inositol lipid 3-phosphatase with novel substrate specificity.

PubMed ID: 11676921

DOI: 10.1016/s0960-9822(01)00501-2

PubMed ID: 12646134

Title: Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatases.

PubMed ID: 12646134

DOI: 10.1016/s0960-9822(03)00132-5

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 32690950

Title: STEEP mediates STING ER exit and activation of signaling.

PubMed ID: 32690950

DOI: 10.1038/s41590-020-0730-5

PubMed ID: 32929276

Title:

PubMed ID: 32929276

DOI: 10.1038/s41590-020-0803-5

Sequence Information:

Length: 1198
Mass: 133619
Checksum: FE6F4B165074D5F8
Sequence:

MDEETRHSLE CIQANQIFPR KQLIREDENL QVPFLELHGE STEFVGRAED AIIALSNYRL 
HIKFKESLVN VPLQLIESVE CRDIFQLHLT CKDCKVIRCQ FSTFEQCQEW LKRLNNAIRP 
PAKIEDLFSF AYHAWCMEVY ASEKEQHGDL CRPGEHVTSR FKNEVERMGF DMNNAWRISN 
INEKYKLCGS YPQELIVPAW ITDKELESVS SFRSWKRIPA VIYRHQSNGA VIARCGQPEV 
SWWGWRNADD EHLVQSVAKA CASDSRSSGS KLSTRNTSRD FPNGGDLSDV EFDSSLSNAS 
GAESLAIQPQ KLLILDARSY AAAVANRAKG GGCECPEYYP NCEVVFMGMA NIHSIRRSFQ 
SLRLLCTQMP DPGNWLSALE STKWLHHLSV LLKSALLVVH AVDQDQRPVL VHCSDGWDRT 
PQIVALAKLL LDPYYRTIEG FQVLVEMEWL DFGHKFADRC GHGENSDDLN ERCPVFLQWL 
DCVHQLQRQF PCSFEFNEAF LVKLVQHTYS CLFGTFLCNN AKERGEKHTQ ERTCSVWSLL 
RAGNKAFKNL LYSSQSEAVL YPVCHVRNLM LWSAVYLPCP SPTTPVDDSC APYPAPGTSP 
DDPPLSRLPK TRSYDNLTTA CDNTVPLASR RCSDPSLNEK WQEHRRSLEL SSLAGPGEDP 
LSADSLGKPT RVPGGAELSV AAGVAEGQME NILQEATKEE SGVEEPAHRA GIEIQEGKED 
PLLEKESRRK TPEASAIGLH QDPELGDAAL RSHLDMSWPL FSQGISEQQS GLSVLLSSLQ 
VPPRGEDSLE VPVEQFRIEE IAEGREEAVL PIPVDAKVGY GTSQSCSLLP SQVPFETRGP 
NVDSSTDMLV EDKVKSVSGP QGHHRSCLVN SGKDRLPQTM EPSPSETSLV ERPQVGSVVH 
RTSLGSTLSL TRSPCALPLA ECKEGLVCNG APETENRASE QPPGLSTLQM YPTPNGHCAN 
GEAGRSKDSL SRQLSAMSCS SAHLHSRNLH HKWLHSHSGR PSATSSPDQP SRSHLDDDGM 
SVYTDTIQQR LRQIESGHQQ EVETLKKQVQ ELKSRLESQY LTSSLHFNGD FGDEVTSIPD 
SESNLDQNCL SRCSTEIFSE ASWEQVDKQD TEMTRWLPDH LAAHCYACDS AFWLASRKHH 
CRNCGNVFCS SCCNQKVPVP SQQLFEPSRV CKSCYSSLHP TSSSIDLELD KPIAATSN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: MTMR3

Associated with

Other Information

FYVE-DSP1, a dual-specificity protein phosphatase containing an FYVE domain. PubMed ID: 10733931

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. PubMed ID: 9205841

A genome annotation-driven approach to cloning the human ORFeome. PubMed ID: 15461802

The DNA sequence of human chromosome 22. PubMed ID: 10591208

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human. PubMed ID: 9736772

A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast. PubMed ID: 8640223

Characterization of MTMR3. an inositol lipid 3-phosphatase with novel substrate specificity. PubMed ID: 11676921

Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatases. PubMed ID: 12646134

Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. PubMed ID: 18220336

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974

STEEP mediates STING ER exit and activation of signaling. PubMed ID: 32690950