Details for: CACNA1G

Gene ID: 8913

Symbol: CACNA1G

Ensembl ID: ENSG00000006283

Description: calcium voltage-gated channel subunit alpha1 G

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 2.25
    Marker Score: 2,712
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.06
    Marker Score: 69,723
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.61
    Marker Score: 1,172
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.48
    Marker Score: 2,801
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.38
    Marker Score: 873
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 1.34
    Marker Score: 2,776
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.18
    Marker Score: 489
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.18
    Marker Score: 12,160
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4,816
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.1
    Marker Score: 7,304
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.09
    Marker Score: 16,999
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.09
    Marker Score: 8,324
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.08
    Marker Score: 4,387
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.06
    Marker Score: 21,179
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.05
    Marker Score: 800
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.03
    Marker Score: 374
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.03
    Marker Score: 37,959
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.01
    Marker Score: 687
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.01
    Marker Score: 2,055
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,827
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,051
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.99
    Marker Score: 511
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.99
    Marker Score: 3,828
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.99
    Marker Score: 521
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.98
    Marker Score: 464
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,408
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.96
    Marker Score: 305
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.95
    Marker Score: 2,249
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,413
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5,352
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.94
    Marker Score: 375
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 0.93
    Marker Score: 940
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.93
    Marker Score: 428
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.92
    Marker Score: 2,741
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.91
    Marker Score: 327
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,288
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,264
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 710
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.77
    Marker Score: 398
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.76
    Marker Score: 291
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.75
    Marker Score: 234
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.73
    Marker Score: 27,885
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.73
    Marker Score: 464
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7
    Marker Score: 180
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 0.67
    Marker Score: 2,773
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.66
    Marker Score: 5,698
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.66
    Marker Score: 510
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.65
    Marker Score: 1,311
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.64
    Marker Score: 426
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.63
    Marker Score: 299
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.59
    Marker Score: 189
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.58
    Marker Score: 460
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.56
    Marker Score: 149
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.56
    Marker Score: 234
  • Cell Name: Unknown (CL0002371)
    Fold Change: 0.56
    Marker Score: 592
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.55
    Marker Score: 33,926
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 0.55
    Marker Score: 519
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 0.53
    Marker Score: 380
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.53
    Marker Score: 642
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.52
    Marker Score: 17,736
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.52
    Marker Score: 310
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.49
    Marker Score: 5,483
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.43
    Marker Score: 6,373
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 0.4
    Marker Score: 2,141
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.39
    Marker Score: 101
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.38
    Marker Score: 167
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.37
    Marker Score: 373
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.37
    Marker Score: 117
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.36
    Marker Score: 613
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 0.35
    Marker Score: 1,623
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 0.34
    Marker Score: 191
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 0.33
    Marker Score: 194
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.32
    Marker Score: 3,067
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.32
    Marker Score: 497
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.32
    Marker Score: 1,120
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.29
    Marker Score: 1,873
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 0.27
    Marker Score: 802
  • Cell Name: meningeal macrophage (CL0000879)
    Fold Change: 0.27
    Marker Score: 76
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 0.26
    Marker Score: 77
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 0.26
    Marker Score: 262
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 0.25
    Marker Score: 3,344
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.25
    Marker Score: 312
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.23
    Marker Score: 139
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.23
    Marker Score: 65
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 0.23
    Marker Score: 64
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 0.22
    Marker Score: 513
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.22
    Marker Score: 929
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.22
    Marker Score: 75
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.22
    Marker Score: 92
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 0.21
    Marker Score: 102
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 0.21
    Marker Score: 76
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 0.2
    Marker Score: 65
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.2
    Marker Score: 75
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.2
    Marker Score: 195
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: 0.2
    Marker Score: 78
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.2
    Marker Score: 193
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.19
    Marker Score: 112
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 0.19
    Marker Score: 99
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: 0.19
    Marker Score: 65
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.19
    Marker Score: 161

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CACNA1G is a member of the voltage-gated calcium channel family, which is composed of four subunits (α, β, γ, and δ). The α1 subunit, encoded by CACNA1G, is the most studied and is responsible for the pore-forming activity of the channel. CACNA1G is predominantly expressed in the heart and nervous system, where it plays a critical role in regulating calcium influx and membrane potential. **Pathways and Functions:** CACNA1G is involved in various cellular processes, including: 1. **Cardiac Conduction:** CACNA1G is essential for the regulation of atrial and ventricular cardiac muscle cell membrane depolarization, which is crucial for maintaining a normal heart rate. 2. **Neuronal Signaling:** The channel is involved in the regulation of neurotransmitter release and synaptic transmission in the nervous system. 3. **Muscle Contraction:** CACNA1G is necessary for the contraction of smooth muscle cells and cardiac muscle cells. 4. **Cell Signaling:** The channel is involved in various signaling pathways, including those mediated by Ncam1 and nickel cations. **Mechanisms of Action:** CACNA1G channels are voltage-gated, meaning that their activity is regulated by changes in membrane potential. When the membrane potential reaches a threshold, the channel opens, allowing calcium ions to flow into the cell. This influx of calcium ions triggers a series of downstream signaling events, including the activation of protein kinases and the regulation of gene expression. **Clinical Significance:** Dysregulation of CACNA1G has been implicated in various cardiovascular and neurological disorders, including: 1. **Arrhythmias:** Mutations in CACNA1G have been associated with atrial fibrillation and other cardiac arrhythmias. 2. **Hypertension:** Abnormalities in CACNA1G function have been linked to hypertension and cardiovascular disease. 3. **Neurodegenerative Disorders:** CACNA1G has been implicated in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. **Conclusion:** In conclusion, CACNA1G is a crucial gene that plays a pivotal role in regulating calcium signaling and cardiac function. Its dysregulation has been implicated in various cardiovascular and neurological disorders, highlighting the importance of understanding the mechanisms of CACNA1G in maintaining normal cellular function. Further research is needed to elucidate the complexities of CACNA1G function and its role in human disease.

Genular Protein ID: 701312072

Symbol: CAC1G_HUMAN

Name: Voltage-dependent T-type calcium channel subunit alpha-1G

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10493502

Title: Inactivation of CACNA1G, a T-type calcium channel gene, by aberrant methylation of its 5' CpG island in human tumors.

PubMed ID: 10493502

PubMed ID: 10548410

Title: Structure and alternative splicing of the gene encoding alpha1G, a human brain T calcium channel alpha1 subunit.

PubMed ID: 10548410

DOI: 10.1016/s0304-3940(99)00716-8

PubMed ID: 10648811

Title: Molecular cloning and functional expression of ca(v)3.1c, a T-type calcium channel from human brain.

PubMed ID: 10648811

DOI: 10.1016/s0014-5793(99)01756-1

PubMed ID: 10692398

Title: Molecular and functional properties of the human alpha1G subunit that forms T-type calcium channels.

PubMed ID: 10692398

DOI: 10.1074/jbc.275.9.6090

PubMed ID: 16671074

Title: Profiling the array of Ca(v)3.1 variants from the human T-type calcium channel gene CACNA1G: alternative structures, developmental expression, and biophysical variations.

PubMed ID: 16671074

DOI: 10.1002/prot.20877

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10574461

Title: Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.

PubMed ID: 10574461

DOI: 10.1093/dnares/6.5.329

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 9495342

Title: Molecular characterization of a neuronal low-voltage-activated T-type calcium channel.

PubMed ID: 9495342

DOI: 10.1038/36110

PubMed ID: 26456284

Title: A recurrent mutation in CACNA1G alters Cav3.1 T-type calcium-channel conduction and causes autosomal-dominant cerebellar ataxia.

PubMed ID: 26456284

DOI: 10.1016/j.ajhg.2015.09.007

PubMed ID: 26715324

Title: A mutation in the low voltage-gated calcium channel CACNA1G alters the physiological properties of the channel, causing spinocerebellar ataxia.

PubMed ID: 26715324

DOI: 10.1186/s13041-015-0180-4

PubMed ID: 29878067

Title: De novo mutation screening in childhood-onset cerebellar atrophy identifies gain-of-function mutations in the CACNA1G calcium channel gene.

PubMed ID: 29878067

DOI: 10.1093/brain/awy145

Sequence Information:

  • Length: 2377
  • Mass: 262472
  • Checksum: 1C9F7C557D9D32DF
  • Sequence:
  • MDEEEDGAGA EESGQPRSFM RLNDLSGAGG RPGPGSAEKD PGSADSEAEG LPYPALAPVV 
    FFYLSQDSRP RSWCLRTVCN PWFERISMLV ILLNCVTLGM FRPCEDIACD SQRCRILQAF 
    DDFIFAFFAV EMVVKMVALG IFGKKCYLGD TWNRLDFFIV IAGMLEYSLD LQNVSFSAVR 
    TVRVLRPLRA INRVPSMRIL VTLLLDTLPM LGNVLLLCFF VFFIFGIVGV QLWAGLLRNR 
    CFLPENFSLP LSVDLERYYQ TENEDESPFI CSQPRENGMR SCRSVPTLRG DGGGGPPCGL 
    DYEAYNSSSN TTCVNWNQYY TNCSAGEHNP FKGAINFDNI GYAWIAIFQV ITLEGWVDIM 
    YFVMDAHSFY NFIYFILLII VGSFFMINLC LVVIATQFSE TKQRESQLMR EQRVRFLSNA 
    STLASFSEPG SCYEELLKYL VYILRKAARR LAQVSRAAGV RVGLLSSPAP LGGQETQPSS 
    SCSRSHRRLS VHHLVHHHHH HHHHYHLGNG TLRAPRASPE IQDRDANGSR RLMLPPPSTP 
    ALSGAPPGGA ESVHSFYHAD CHLEPVRCQA PPPRSPSEAS GRTVGSGKVY PTVHTSPPPE 
    TLKEKALVEV AASSGPPTLT SLNIPPGPYS SMHKLLETQS TGACQSSCKI SSPCLKADSG 
    ACGPDSCPYC ARAGAGEVEL ADREMPDSDS EAVYEFTQDA QHSDLRDPHS RRQRSLGPDA 
    EPSSVLAFWR LICDTFRKIV DSKYFGRGIM IAILVNTLSM GIEYHEQPEE LTNALEISNI 
    VFTSLFALEM LLKLLVYGPF GYIKNPYNIF DGVIVVISVW EIVGQQGGGL SVLRTFRLMR 
    VLKLVRFLPA LQRQLVVLMK TMDNVATFCM LLMLFIFIFS ILGMHLFGCK FASERDGDTL 
    PDRKNFDSLL WAIVTVFQIL TQEDWNKVLY NGMASTSSWA ALYFIALMTF GNYVLFNLLV 
    AILVEGFQAE EISKREDASG QLSCIQLPVD SQGGDANKSE SEPDFFSPSL DGDGDRKKCL 
    ALVSLGEHPE LRKSLLPPLI IHTAATPMSL PKSTSTGLGE ALGPASRRTS SSGSAEPGAA 
    HEMKSPPSAR SSPHSPWSAA SSWTSRRSSR NSLGRAPSLK RRSPSGERRS LLSGEGQESQ 
    DEEESSEEER ASPAGSDHRH RGSLEREAKS SFDLPDTLQV PGLHRTASGR GSASEHQDCN 
    GKSASGRLAR ALRPDDPPLD GDDADDEGNL SKGERVRAWI RARLPACCLE RDSWSAYIFP 
    PQSRFRLLCH RIITHKMFDH VVLVIIFLNC ITIAMERPKI DPHSAERIFL TLSNYIFTAV 
    FLAEMTVKVV ALGWCFGEQA YLRSSWNVLD GLLVLISVID ILVSMVSDSG TKILGMLRVL 
    RLLRTLRPLR VISRAQGLKL VVETLMSSLK PIGNIVVICC AFFIIFGILG VQLFKGKFFV 
    CQGEDTRNIT NKSDCAEASY RWVRHKYNFD NLGQALMSLF VLASKDGWVD IMYDGLDAVG 
    VDQQPIMNHN PWMLLYFISF LLIVAFFVLN MFVGVVVENF HKCRQHQEEE EARRREEKRL 
    RRLEKKRRNL MLDDVIASGS SASAASEAQC KPYYSDYSRF RLLVHHLCTS HYLDLFITGV 
    IGLNVVTMAM EHYQQPQILD EALKICNYIF TVIFVLESVF KLVAFGFRRF FQDRWNQLDL 
    AIVLLSIMGI TLEEIEVNAS LPINPTIIRI MRVLRIARVL KLLKMAVGMR ALLDTVMQAL 
    PQVGNLGLLF MLLFFIFAAL GVELFGDLEC DETHPCEGLG RHATFRNFGM AFLTLFRVST 
    GDNWNGIMKD TLRDCDQEST CYNTVISPIY FVSFVLTAQF VLVNVVIAVL MKHLEESNKE 
    AKEEAELEAE LELEMKTLSP QPHSPLGSPF LWPGVEGPDS PDSPKPGALH PAAHARSASH 
    FSLEHPTDRQ LFDTISLLIQ GSLEWELKLM DELAGPGGQP SAFPSAPSLG GSDPQIPLAE 
    MEALSLTSEI VSEPSCSLAL TDDSLPDDMH TLLLSALESN MQPHPTELPG PDLLTVRKSG 
    VSRTHSLPND SYMCRHGSTA EGPLGHRGWG LPKAQSGSVL SVHSQPADTS YILQLPKDAP 
    HLLQPHSAPT WGTIPKLPPP GRSPLAQRPL RRQAAIRTDS LDVQGLGSRE DLLAEVSGPS 
    PPLARAYSFW GQSSTQAQQH SRSHSKISKH MTPPAPCPGP EPNWGKGPPE TRSSLELDTE 
    LSWISGDLLP PGGQEEPPSP RDLKKCYSVE AQSCQRRPTS WLDEQRRHSI AVSCLDSGSQ 
    PHLGTDPSNL GGQPLGGPGS RPKKKLSPPS ITIDPPESQG PRTPPSPGIC LRRRAPSSDS 
    KDPLASGPPD SMAASPSPKK DVLSLSGLSS DPADLDP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.