Details for: CCND3

Gene ID: 896

Symbol: CCND3

Ensembl ID: ENSG00000112576

Description: cyclin D3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 157.1247
    Cell Significance Index: -24.4400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 153.9563
    Cell Significance Index: -39.0500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 115.8400
    Cell Significance Index: -47.7200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 112.0227
    Cell Significance Index: -45.5100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 97.5064
    Cell Significance Index: -46.0400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 94.9677
    Cell Significance Index: -48.8500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 68.7906
    Cell Significance Index: -46.1600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 48.5785
    Cell Significance Index: -46.3800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 35.2730
    Cell Significance Index: -43.4900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 17.9431
    Cell Significance Index: -39.2700
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 17.1695
    Cell Significance Index: 46.0000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 16.9561
    Cell Significance Index: -52.0800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.9461
    Cell Significance Index: -47.1400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.6870
    Cell Significance Index: -25.9500
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 9.2388
    Cell Significance Index: 82.0100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 4.4782
    Cell Significance Index: 131.5200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 3.8805
    Cell Significance Index: 250.3500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.1471
    Cell Significance Index: 87.9500
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 3.0747
    Cell Significance Index: 18.9700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.2392
    Cell Significance Index: 264.0700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.9716
    Cell Significance Index: 52.8300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.6687
    Cell Significance Index: 271.3900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.3946
    Cell Significance Index: 29.7000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.1715
    Cell Significance Index: 31.2800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0764
    Cell Significance Index: 215.9200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9744
    Cell Significance Index: 105.9900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.9362
    Cell Significance Index: 120.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.8961
    Cell Significance Index: 42.1200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.7454
    Cell Significance Index: 20.2900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6967
    Cell Significance Index: 249.8900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.5919
    Cell Significance Index: 10.9400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4475
    Cell Significance Index: 30.9500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3615
    Cell Significance Index: 71.7400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3428
    Cell Significance Index: 151.5700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3243
    Cell Significance Index: 41.9000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3068
    Cell Significance Index: 167.5300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3009
    Cell Significance Index: 54.2400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2367
    Cell Significance Index: 29.1000
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.1952
    Cell Significance Index: 3.4500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1874
    Cell Significance Index: 9.7600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1869
    Cell Significance Index: 35.5700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1172
    Cell Significance Index: 2.9300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1146
    Cell Significance Index: 11.3400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1025
    Cell Significance Index: 192.9200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0987
    Cell Significance Index: 62.6600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0821
    Cell Significance Index: 74.1500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0679
    Cell Significance Index: 46.9800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0604
    Cell Significance Index: 8.2900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0312
    Cell Significance Index: 57.5800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0308
    Cell Significance Index: 23.3500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0289
    Cell Significance Index: 44.5600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0188
    Cell Significance Index: 0.2700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0165
    Cell Significance Index: 1.2700
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.0115
    Cell Significance Index: 0.1900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0075
    Cell Significance Index: 3.4100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0011
    Cell Significance Index: 0.0800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0009
    Cell Significance Index: -0.0400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0125
    Cell Significance Index: -16.9500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0328
    Cell Significance Index: -0.7100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0410
    Cell Significance Index: -30.0500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0541
    Cell Significance Index: -40.0600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0583
    Cell Significance Index: -8.4700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0766
    Cell Significance Index: -43.2000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0792
    Cell Significance Index: -49.4600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0830
    Cell Significance Index: -8.4800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1427
    Cell Significance Index: -41.0500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1484
    Cell Significance Index: -25.3400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1699
    Cell Significance Index: -7.7000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1786
    Cell Significance Index: -10.9800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2217
    Cell Significance Index: -11.6400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2271
    Cell Significance Index: -26.0200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.2288
    Cell Significance Index: -1.5500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2336
    Cell Significance Index: -49.2000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2617
    Cell Significance Index: -30.5000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2760
    Cell Significance Index: -4.7300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.3162
    Cell Significance Index: -9.1100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3398
    Cell Significance Index: -8.6800
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.3414
    Cell Significance Index: -4.9100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3557
    Cell Significance Index: -37.0400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3685
    Cell Significance Index: -26.0600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3938
    Cell Significance Index: -26.4800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.4379
    Cell Significance Index: -22.7500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4703
    Cell Significance Index: -12.5800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5024
    Cell Significance Index: -13.2100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5537
    Cell Significance Index: -43.8500
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.5944
    Cell Significance Index: -5.9600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6081
    Cell Significance Index: -38.3300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6803
    Cell Significance Index: -21.7900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.6929
    Cell Significance Index: -38.8800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.7101
    Cell Significance Index: -35.8900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.7302
    Cell Significance Index: -12.2200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7354
    Cell Significance Index: -32.5300
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.7553
    Cell Significance Index: -11.4900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7645
    Cell Significance Index: -46.8700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.8015
    Cell Significance Index: -15.6400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.8266
    Cell Significance Index: -23.5900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.8420
    Cell Significance Index: -31.8900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.8838
    Cell Significance Index: -30.7100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.0016
    Cell Significance Index: -31.9000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.0067
    Cell Significance Index: -32.9600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cell Cycle Regulation:** CCND3 is a key regulator of the G1/S transition, promoting cell cycle progression and proliferation. 2. **Cyclin-Dependent Kinase (CDK) Activity:** CCND3 interacts with CDK4/6, activating the cyclin-dependent protein kinase complex, which drives cell cycle progression. 3. **Protein Phosphorylation:** CCND3 regulates protein phosphorylation, influencing various signaling pathways, including the MAPK6/4 pathway. 4. **Transcriptional Regulation:** CCND3 interacts with RNA polymerase II, modulating gene expression and transcriptional regulation. **Pathways and Functions:** 1. **Aberrant Regulation of Mitotic Cell Cycle:** CCND3 is involved in the aberrant regulation of the mitotic cell cycle, particularly in cancer cells, where it can contribute to tumorigenesis. 2. **Regulation of Immune Cell Proliferation:** CCND3 plays a crucial role in regulating immune cell proliferation, particularly in T cells, where it influences T cell activation, differentiation, and survival. 3. **Negative Regulation of Transcription:** CCND3 can negatively regulate transcription by RNA polymerase II, modulating gene expression and transcriptional regulation. 4. **Positive Regulation of Cyclin-Dependent Kinase Activity:** CCND3 can positively regulate CDK activity, promoting cell cycle progression and proliferation. **Clinical Significance:** 1. **Cancer:** CCND3 overexpression has been linked to various cancers, including breast, lung, and colon cancer, where it can contribute to tumorigenesis and cancer progression. 2. **Autoimmune Disorders:** CCND3 dysregulation has been implicated in autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis, where it can contribute to immune cell dysfunction and disease progression. 3. **Inflammatory Conditions:** CCND3 is involved in the regulation of inflammatory responses, particularly in T cells, where it can influence T cell activation, differentiation, and survival. 4. **Immunotherapy:** CCND3 has been identified as a potential target for immunotherapy, particularly in cancer treatment, where it can be used to modulate immune cell proliferation and function. In conclusion, CCND3 is a complex gene that plays a pivotal role in regulating the cell cycle, immune cell proliferation, and transcriptional regulation. Its dysregulation has been implicated in various diseases, including cancer, autoimmune disorders, and inflammatory conditions. Further research is needed to fully understand the mechanisms by which CCND3 regulates cell cycle progression and immune cell function, and to explore its potential as a therapeutic target in disease treatment.

Genular Protein ID: 318463773

Symbol: CCND3_HUMAN

Name: N/A

UniProtKB Accession Codes:

P30281 B2RD63 B3KQ22 E9PAS4 E9PB36 Q5T8J0 Q6FG62 Q96F49

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 2 CORUM 1 CPTAC 2 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 16 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 6 RefSeq 6 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1386336

Title: Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins.

PubMed ID: 1386336

DOI: 10.1016/0888-7543(92)90127-e

PubMed ID: 1383201

Title: Cloning and characterization of human cyclin D3, a cDNA closely related in sequence to the PRAD1/cyclin D1 proto-oncogene.

PubMed ID: 1383201

DOI: 10.1016/s0021-9258(19)88717-3

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1386335

Title: Genomic organization, chromosomal localization, and independent expression of human cyclin D genes.

PubMed ID: 1386335

DOI: 10.1016/0888-7543(92)90126-d

PubMed ID: 8114739

Title: Identification of G1 kinase activity for cdk6, a novel cyclin D partner.

PubMed ID: 8114739

DOI: 10.1128/mcb.14.3.2077-2086.1994

PubMed ID: 9106657

Title: New functional activities for the p21 family of CDK inhibitors.

PubMed ID: 9106657

DOI: 10.1101/gad.11.7.847

PubMed ID: 15358120

Title: Cyclin D3 interacts with human activating transcription factor 5 and potentiates its transcription activity.

PubMed ID: 15358120

DOI: 10.1016/j.bbrc.2004.07.053

PubMed ID: 15327989

Title: Identification of the p28 subunit of eukaryotic initiation factor 3(eIF3k) as a new interaction partner of cyclin D3.

PubMed ID: 15327989

DOI: 10.1016/j.febslet.2004.07.071

PubMed ID: 16782892

Title: Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK 'inhibitors'.

PubMed ID: 16782892

DOI: 10.1128/mcb.02006-05

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 22020328

Title: F-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest.

PubMed ID: 22020328

DOI: 10.1038/onc.2011.432

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 33854235

Title: CRL4AMBRA1 is a master regulator of D-type cyclins.

PubMed ID: 33854235

DOI: 10.1038/s41586-021-03445-y

PubMed ID: 33854239

Title: The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D.

PubMed ID: 33854239

DOI: 10.1038/s41586-021-03474-7

PubMed ID: 19237555

Title: The structure of CDK4/cyclin D3 has implications for models of CDK activation.

PubMed ID: 19237555

DOI: 10.1073/pnas.0809674106

Sequence Information:

  • Length: 292
  • Mass: 32520
  • Checksum: 16E7B1604FEB0029
  • Sequence:
    • MELLCCEGTR HAPRAGPDPR LLGDQRVLQS LLRLEERYVP RASYFQCVQR EIKPHMRKML 
AYWMLEVCEE QRCEEEVFPL AMNYLDRYLS CVPTRKAQLQ LLGAVCMLLA SKLRETTPLT 
IEKLCIYTDH AVSPRQLRDW EVLVLGKLKW DLAAVIAHDF LAFILHRLSL PRDRQALVKK 
HAQTFLALCA TDYTFAMYPP SMIATGSIGA AVQGLGACSM SGDELTELLA GITGTEVDCL 
RACQEQIEAA LRESLREASQ TSSSPAPKAP RGSSSQGPSQ TSTPTDVTAI HL

Genular Protein ID: 282581155

Symbol: B3KP19_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KP19

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RefSeq 1 RuleBase 1 SAM 1 SMART 4 SMR 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 242
  • Mass: 26245
  • Checksum: 125ABA333F65A920
  • Sequence:
    • MKSAGGSGRS LLPSPRVCEE QRCEEEVFPL AMNYLDRYLS CVPTRKAQLQ LLGAVCMLLA 
SKLRETTPLT IEKLCIYTDH AVSPRQLRDW EVLVLGKLKW DLAAVIAHDF LAFILHRLSL 
PRDRQALVKK HAQTFLALCA TDYTFVMYPP SMIATGSIGA AVQGLGACSM SGDELTELLA 
GITGTEVDCL RACQEQIEAA LRESLREAAQ TSSSPAPKAP RGSSSQGPSQ TSTPTDVTAI 
HL

Genular Protein ID: 3649261100

Symbol: Q5T8J1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5T8J1

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SAM 1 SMART 4 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 242
  • Mass: 26233
  • Checksum: 0CBD534DB16B5730
  • Sequence:
    • MKSAGGSGRS LLPSPRVCEE QRCEEEVFPL AMNYLDRYLS CVPTRKAQLQ LLGAVCMLLA 
SKLRETTPLT IEKLCIYTDH AVSPRQLRDW EVLVLGKLKW DLAAVIAHDF LAFILHRLSL 
PRDRQALVKK HAQTFLALCA TDYTFAMYPP SMIATGSIGA AVQGLGACSM SGDELTELLA 
GITGTEVDCL RACQEQIEAA LRESLREASQ TSSSPAPKAP RGSSSQGPSQ TSTPTDVTAI 
HL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.