Details for: CCND3P1

Gene ID: 897

Symbol: CCND3P1

Ensembl ID: ENSG00000224473

Description: cyclin D3 pseudogene 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1928
    Cell Significance Index: 2.6300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.1545
    Cell Significance Index: 2.2000
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 0.1488
    Cell Significance Index: 2.0900
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.1099
    Cell Significance Index: 1.4200
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0581
    Cell Significance Index: 1.4500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0474
    Cell Significance Index: 2.2100
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.0222
    Cell Significance Index: 0.2500
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 0.0082
    Cell Significance Index: 0.1000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0059
    Cell Significance Index: 0.3000
  • Cell Name: pericyte (CL0000669)
    Fold Change: 0.0039
    Cell Significance Index: 0.0500
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 0.0028
    Cell Significance Index: 0.0300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0003
    Cell Significance Index: 0.0300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0007
    Cell Significance Index: -1.3100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0013
    Cell Significance Index: -0.2700
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0021
    Cell Significance Index: -0.0200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0022
    Cell Significance Index: -1.4000
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0033
    Cell Significance Index: -0.0500
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0049
    Cell Significance Index: -0.0500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0062
    Cell Significance Index: -0.2000
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.0063
    Cell Significance Index: -0.0600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0073
    Cell Significance Index: -0.2400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0090
    Cell Significance Index: -0.1900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0092
    Cell Significance Index: -1.3400
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0092
    Cell Significance Index: -0.1200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0092
    Cell Significance Index: -0.2300
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.0108
    Cell Significance Index: -0.1200
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.0138
    Cell Significance Index: -0.1200
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0169
    Cell Significance Index: -0.2000
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0221
    Cell Significance Index: -0.2100
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.0221
    Cell Significance Index: -0.1400
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.0287
    Cell Significance Index: -0.2700
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0317
    Cell Significance Index: -0.4100
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: -0.0341
    Cell Significance Index: -0.3500
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.0361
    Cell Significance Index: -0.3900
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.0365
    Cell Significance Index: -0.3000
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0377
    Cell Significance Index: -0.4000
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0381
    Cell Significance Index: -0.4500
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.0388
    Cell Significance Index: -0.4400
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.0394
    Cell Significance Index: -0.4000
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.0508
    Cell Significance Index: -0.6400
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.0532
    Cell Significance Index: -0.4800
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0549
    Cell Significance Index: -0.6200
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0553
    Cell Significance Index: -0.7600
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0610
    Cell Significance Index: -0.5800
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0643
    Cell Significance Index: -0.7900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0664
    Cell Significance Index: -1.4600
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0664
    Cell Significance Index: -0.7900
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.0664
    Cell Significance Index: -0.6100
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.0668
    Cell Significance Index: -0.5800
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0675
    Cell Significance Index: -0.7100
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0679
    Cell Significance Index: -0.7400
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0682
    Cell Significance Index: -0.6400
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0692
    Cell Significance Index: -0.6100
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0895
    Cell Significance Index: -1.5200
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.1147
    Cell Significance Index: -1.3900
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.1249
    Cell Significance Index: -1.1000
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.1315
    Cell Significance Index: -1.6600
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.1321
    Cell Significance Index: -1.5800
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.1333
    Cell Significance Index: -1.7400
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.1339
    Cell Significance Index: -1.6800
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.1346
    Cell Significance Index: -1.5400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1346
    Cell Significance Index: -1.6100
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.1390
    Cell Significance Index: -1.6700
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.1391
    Cell Significance Index: -1.6000
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: -0.1412
    Cell Significance Index: -1.6800
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.1417
    Cell Significance Index: -1.6700
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.1425
    Cell Significance Index: -1.6100
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.1483
    Cell Significance Index: -0.8800
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.1514
    Cell Significance Index: -2.0600
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.1571
    Cell Significance Index: -1.6900
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1625
    Cell Significance Index: -1.5400
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.1640
    Cell Significance Index: -1.0300
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: -0.1813
    Cell Significance Index: -2.0300
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.1985
    Cell Significance Index: -1.8600
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.2047
    Cell Significance Index: -1.6900
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.2197
    Cell Significance Index: -1.6900
  • Cell Name: goblet cell (CL0000160)
    Fold Change: -0.2289
    Cell Significance Index: -2.0700
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.2409
    Cell Significance Index: -2.2300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Pseudogenic nature:** CCND3P1 is a non-functional homolog of the cyclin D3 gene, which suggests that it may have evolved from a functional gene through genetic drift or gene duplication. 2. **Widespread expression:** CCND3P1 is expressed in a diverse range of cell types, including astrocytes, melanocytes, and immune cells such as B cells and memory B cells. 3. **Cell type-specific expression:** The expression of CCND3P1 is cell type-specific, with some cell types exhibiting higher levels of expression than others. 4. **Regulatory role:** CCND3P1 may play a regulatory role in cell differentiation, proliferation, and survival, although the exact mechanisms are not yet fully understood. **Pathways and Functions:** 1. **Cell cycle regulation:** CCND3P1 may contribute to the regulation of the cell cycle, particularly in the context of cell differentiation and proliferation. 2. **Cell differentiation:** CCND3P1 may influence cell differentiation processes, such as the development of melanocytes or B cells. 3. **Apoptosis regulation:** CCND3P1 may also modulate apoptosis, or programmed cell death, in certain cell types. 4. **Immune system development:** CCND3P1 may play a role in the development and maturation of immune cells, such as B cells and memory B cells. **Clinical Significance:** 1. **Cancer association:** The expression of CCND3P1 has been linked to various types of cancer, including breast, colon, and lung cancer, suggesting that it may serve as a prognostic biomarker. 2. **Immune system disorders:** CCND3P1 may also contribute to the development of immune system disorders, such as autoimmune diseases or immunodeficiency syndromes. 3. **Tumor microenvironment:** CCND3P1 may modulate the tumor microenvironment, influencing the behavior of cancer cells and the immune response. 4. **Potential therapeutic target:** CCND3P1 may serve as a potential therapeutic target for the treatment of cancer and immune system disorders. In conclusion, CCND3P1 is a complex pseudogene that exhibits multifaceted functions in the immune system. Further research is warranted to fully elucidate the mechanisms by which CCND3P1 regulates cell differentiation, proliferation, and survival, as well as its clinical significance in various diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.