Details for: MGAM
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: amacrine cell (CL0000561)
Fold Change: 9.49
Marker Score: 30,386 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 4.26
Marker Score: 12,417 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 2.59
Marker Score: 7,444 - Cell Name: enterocyte of colon (CL1000347)
Fold Change: 2.1
Marker Score: 3,243 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 2.08
Marker Score: 17,560 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 1.96
Marker Score: 5,807 - Cell Name: mural cell (CL0008034)
Fold Change: 1.48
Marker Score: 169,257 - Cell Name: enterocyte of epithelium proper of ileum (CL1000342)
Fold Change: 1.24
Marker Score: 357 - Cell Name: goblet cell (CL0000160)
Fold Change: 1.15
Marker Score: 7,649 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.14
Marker Score: 2,677 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.04
Marker Score: 798 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.01
Marker Score: 683 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1
Marker Score: 323 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.99
Marker Score: 510 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.98
Marker Score: 464 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,409 - Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 0.97
Marker Score: 335 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,412 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5,287 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,739 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.91
Marker Score: 327 - Cell Name: enterocyte (CL0000584)
Fold Change: 0.9
Marker Score: 4,327 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,288 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.78
Marker Score: 314 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,267 - Cell Name: brush cell (CL0002204)
Fold Change: 0.77
Marker Score: 703 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.71
Marker Score: 702 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7
Marker Score: 179 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.67
Marker Score: 2,820 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.65
Marker Score: 292 - Cell Name: neutrophil (CL0000775)
Fold Change: 0.65
Marker Score: 395 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.65
Marker Score: 13,767 - Cell Name: retina horizontal cell (CL0000745)
Fold Change: 0.63
Marker Score: 600 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.62
Marker Score: 410 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.62
Marker Score: 362 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.59
Marker Score: 377 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 442 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.54
Marker Score: 363 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.51
Marker Score: 1,824 - Cell Name: podocyte (CL0000653)
Fold Change: 0.49
Marker Score: 180 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.47
Marker Score: 195 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.45
Marker Score: 193 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.39
Marker Score: 390 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.38
Marker Score: 119 - Cell Name: type L enteroendocrine cell (CL0002279)
Fold Change: 0.37
Marker Score: 102 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.37
Marker Score: 95 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.36
Marker Score: 1,382 - Cell Name: M cell of gut (CL0000682)
Fold Change: 0.34
Marker Score: 89 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.34
Marker Score: 190 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.32
Marker Score: 244 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.31
Marker Score: 313 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.31
Marker Score: 2,905 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.31
Marker Score: 471 - Cell Name: myelocyte (CL0002193)
Fold Change: 0.3
Marker Score: 131 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 0.27
Marker Score: 103 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.27
Marker Score: 386 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.27
Marker Score: 1,634 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.27
Marker Score: 178 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.27
Marker Score: 2,534 - Cell Name: natural killer cell (CL0000623)
Fold Change: 0.24
Marker Score: 317 - Cell Name: neuron (CL0000540)
Fold Change: 0.24
Marker Score: 984 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.24
Marker Score: 71 - Cell Name: precursor cell (CL0011115)
Fold Change: 0.24
Marker Score: 58 - Cell Name: interneuron (CL0000099)
Fold Change: 0.24
Marker Score: 108 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.23
Marker Score: 807 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.23
Marker Score: 446 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.23
Marker Score: 196 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.23
Marker Score: 243 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 0.22
Marker Score: 559 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.22
Marker Score: 64 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.22
Marker Score: 271 - Cell Name: promonocyte (CL0000559)
Fold Change: 0.22
Marker Score: 144 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.22
Marker Score: 346 - Cell Name: lymphocyte (CL0000542)
Fold Change: 0.21
Marker Score: 107 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.21
Marker Score: 56 - Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: 0.21
Marker Score: 546 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.21
Marker Score: 66 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.21
Marker Score: 3,073 - Cell Name: classical monocyte (CL0000860)
Fold Change: 0.2
Marker Score: 814 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.19
Marker Score: 206 - Cell Name: glial cell (CL0000125)
Fold Change: 0.19
Marker Score: 210 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.19
Marker Score: 98 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 0.18
Marker Score: 1,170 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.18
Marker Score: 6,816 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.18
Marker Score: 65 - Cell Name: paneth cell (CL0000510)
Fold Change: 0.18
Marker Score: 124 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 0.18
Marker Score: 496 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.17
Marker Score: 59 - Cell Name: blood vessel smooth muscle cell (CL0019018)
Fold Change: 0.17
Marker Score: 45 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.17
Marker Score: 712 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.17
Marker Score: 1,302 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.17
Marker Score: 69 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.16
Marker Score: 154 - Cell Name: mast cell (CL0000097)
Fold Change: 0.16
Marker Score: 93 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.16
Marker Score: 39 - Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
Fold Change: 0.16
Marker Score: 121 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.16
Marker Score: 210 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.16
Marker Score: 9,545 - Cell Name: intestine goblet cell (CL0019031)
Fold Change: 0.15
Marker Score: 147 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.15
Marker Score: 144
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 560213022
Symbol: MGA_HUMAN
Name: Alpha-1,4-glucosidase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9446624
Title: Human small intestinal maltase-glucoamylase cDNA cloning. Homology to sucrase-isomaltase.
PubMed ID: 9446624
PubMed ID: 12853948
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 24309898
Title: Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics.
PubMed ID: 24309898
PubMed ID: 3121301
Title: Tyrosine sulfation, a post-translational modification of microvillar enzymes in the small intestinal enterocyte.
PubMed ID: 3121301
PubMed ID: 3143729
Title: Structure, biosynthesis, and glycosylation of human small intestinal maltase-glucoamylase.
PubMed ID: 3143729
PubMed ID: 12547908
Title: The maltase-glucoamylase gene: common ancestry to sucrase-isomaltase with complementary starch digestion activities.
PubMed ID: 12547908
PubMed ID: 18356321
Title: Luminal starch substrate brake on maltase-glucoamylase activity is located within the glucoamylase subunit.
PubMed ID: 18356321
DOI: 10.1093/jn/138.4.685
PubMed ID: 22058037
Title: Structural insight into substrate specificity of human intestinal maltase-glucoamylase.
PubMed ID: 22058037
PubMed ID: 27480812
Title: Contribution of the Individual Small Intestinal alpha-Glucosidases to Digestion of Unusual alpha-Linked Glycemic Disaccharides.
PubMed ID: 27480812
PubMed ID: 18036614
Title: Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity.
PubMed ID: 18036614
Sequence Information:
- Length: 2753
- Mass: 312022
- Checksum: 148327B7C5E264EF
- Sequence:
MARKKLKKFT TLEIVLSVLL LVLFIISIVL IVLLAKESLK STAPDPGTTG TPDPGTTGTP DPGTTGTTHA RTTGPPDPGT TGTTPVSAEC PVVNELERIN CIPDQPPTKA TCDQRGCCWN PQGAVSVPWC YYSKNHSYHV EGNLVNTNAG FTARLKNLPS SPVFGSNVDN VLLTAEYQTS NRFHFKLTDQ TNNRFEVPHE HVQSFSGNAA ASLTYQVEIS RQPFSIKVTR RSNNRVLFDS SIGPLLFADQ FLQLSTRLPS TNVYGLGEHV HQQYRHDMNW KTWPIFNRDT TPNGNGTNLY GAQTFFLCLE DASGLSFGVF LMNSNAMEVV LQPAPAITYR TIGGILDFYV FLGNTPEQVV QEYLELIGRP ALPSYWALGF HLSRYEYGTL DNMREVVERN RAAQLPYDVQ HADIDYMDER RDFTYDSVDF KGFPEFVNEL HNNGQKLVII VDPAISNNSS SSKPYGPYDR GSDMKIWVNS SDGVTPLIGE VWPGQTVFPD YTNPNCAVWW TKEFELFHNQ VEFDGIWIDM NEVSNFVDGS VSGCSTNNLN NPPFTPRILD GYLFCKTLCM DAVQHWGKQY DIHNLYGYSM AVATAEAAKT VFPNKRSFIL TRSTFAGSGK FAAHWLGDNT ATWDDLRWSI PGVLEFNLFG IPMVGPDICG FALDTPEELC RRWMQLGAFY PFSRNHNGQG YKDQDPASFG ADSLLLNSSR HYLNIRYTLL PYLYTLFFRA HSRGDTVARP LLHEFYEDNS TWDVHQQFLW GPGLLITPVL DEGAEKVMAY VPDAVWYDYE TGSQVRWRKQ KVEMELPGDK IGLHLRGGYI FPTQQPNTTT LASRKNPLGL IIALDENKEA KGELFWDNGE TKDTVANKVY LLCEFSVTQN RLEVNISQST YKDPNNLAFN EIKILGTEEP SNVTVKHNGV PSQTSPTVTY DSNLKVAIIT DIDLLLGEAY TVEWSIKIRD EEKIDCYPDE NGASAENCTA RGCIWEASNS SGVPFCYFVN DLYSVSDVQY NSHGATADIS LKSSVYANAF PSTPVNPLRL DVTYHKNEML QFKIYDPNKN RYEVPVPLNI PSMPSSTPEG QLYDVLIKKN PFGIEIRRKS TGTIIWDSQL LGFTFSDMFI RISTRLPSKY LYGFGETEHR SYRRDLEWHT WGMFSRDQPP GYKKNSYGVH PYYMGLEEDG SAHGVLLLNS NAMDVTFQPL PALTYRTTGG VLDFYVFLGP TPELVTQQYT ELIGRPVMVP YWSLGFQLCR YGYQNDSEIA SLYDEMVAAQ IPYDVQYSDI DYMERQLDFT LSPKFAGFPA LINRMKADGM RVILILDPAI SGNETQPYPA FTRGVEDDVF IKYPNDGDIV WGKVWPDFPD VVVNGSLDWD SQVELYRAYV AFPDFFRNST AKWWKREIEE LYNNPQNPER SLKFDGMWID MNEPSSFVNG AVSPGCRDAS LNHPPYMPHL ESRDRGLSSK TLCMESQQIL PDGSLVQHYN VHNLYGWSQT RPTYEAVQEV TGQRGVVITR STFPSSGRWA GHWLGDNTAA WDQLKKSIIG MMEFSLFGIS YTGADICGFF QDAEYEMCVR WMQLGAFYPF SRNHNTIGTR RQDPVSWDAA FVNISRNVLQ TRYTLLPYLY TLMQKAHTEG VTVVRPLLHE FVSDQVTWDI DSQFLLGPAF LVSPVLERNA RNVTAYFPRA RWYDYYTGVD INARGEWKTL PAPLDHINLH VRGGYILPWQ EPALNTHLSR KNPLGLIIAL DENKEAKGEL FWDDGQTKDT VAKKVYLLCE FSVTQNHLEV TISQSTYKDP NNLAFNEIKI LGMEEPSNVT VKHNGVPSQT SPTVTYDSNL KVAIITDINL FLGEAYTVEW SIKIRDEEKI DCYPDENGDS AENCTARGCI WEASNSSGVP FCYFVNDLYS VSDVQYNSHG ATADISLKSS VHANAFPSTP VNPLRLDVTY HKNEMLQFKI YDPNNNRYEV PVPLNIPSVP SSTPEGQLYD VLIKKNPFGI EIRRKSTGTI IWDSQLLGFT FNDMFIRIST RLPSKYLYGF GETEHTSYRR DLEWHTWGMF SRDQPPGYKK NSYGVHPYYM GLEEDGSAHG VLLLNSNAMD VTFQPLPALT YRTTGGVLDF YVFLGPTPEL VTQQYTELIG RPVMVPYWSL GFQLCRYGYQ NDSEISSLYD EMVAAQIPYD VQYSDIDYME RQLDFTLSPK FAGFPALINR MKADGMRVIL ILDPAISGNE TQPYPAFTRG VEDDVFIKYP NDGDIVWGKV WPDFPDVVVN GSLDWDSQVE LYRAYVAFPD FFRNSTAKWW KREIEELYNN PQNPERSLKF DGMWIDMNEP SSFVNGAVSP GCRDASLNHP PYMPYLESRD RGLSSKTLCM ESQQILPDGS PVQHYNVHNL YGWSQTRPTY EAVQEVTGQR GVVITRSTFP SSGRWAGHWL GDNTAAWDQL KKSIIGMMEF SLFGISYTGA DICGFFQDAE YEMCVRWMQL GAFYPFSRNH NTIGTRRQDP VSWDVAFVNI SRTVLQTRYT LLPYLYTLMH KAHTEGVTVV RPLLHEFVSD QVTWDIDSQF LLGPAFLVSP VLERNARNVT AYFPRARWYD YYTGVDINAR GEWKTLPAPL DHINLHVRGG YILPWQEPAL NTHLSRQKFM GFKIALDDEG TAGGWLFWDD GQSIDTYGKG LYYLASFSAS QNTMQSHIIF NNYITGTNPL KLGYIEIWGV GSVPVTSVSI SVSGMVITPS FNNDPTTQVL SIDVTDRNIS LHNFTSLTWI STL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.