Details for: WASL

Gene ID: 8976

Symbol: WASL

Ensembl ID: ENSG00000106299

Description: WASP like actin nucleation promoting factor

Associated with

Other Information

Genular Protein ID: 3627620897

Symbol: WASL_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9322739

Title: Identification of N-WASP homologs in human and rat brain.

PubMed ID: 9322739

DOI: 10.1016/s0378-1119(97)00184-4

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9422512

Title: Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP.

PubMed ID: 9422512

DOI: 10.1038/34208

PubMed ID: 9582270

Title: Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri.

PubMed ID: 9582270

DOI: 10.1093/emboj/17.10.2767

PubMed ID: 10491394

Title: Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility.

PubMed ID: 10491394

DOI: 10.1083/jcb.146.6.1319

PubMed ID: 16257963

Title: Phosphorylation of WASP by the Cdc42-associated kinase ACK1: dual hydroxyamino acid specificity in a tyrosine kinase.

PubMed ID: 16257963

DOI: 10.1074/jbc.m506996200

PubMed ID: 16234328

Title: NOSTRIN functions as a homotrimeric adaptor protein facilitating internalization of eNOS.

PubMed ID: 16234328

DOI: 10.1242/jcs.02620

PubMed ID: 16767080

Title: Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partners.

PubMed ID: 16767080

DOI: 10.1038/ncb1433

PubMed ID: 17015620

Title: Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells.

PubMed ID: 17015620

DOI: 10.1083/jcb.200605012

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19487689

Title: Sorting nexin 33 induces mammalian cell micronucleated phenotype and actin polymerization by interacting with Wiskott-Aldrich syndrome protein.

PubMed ID: 19487689

DOI: 10.1074/jbc.m109.007278

PubMed ID: 19767742

Title: The bacterial virulence factor InlC perturbs apical cell junctions and promotes cell-to-cell spread of Listeria.

PubMed ID: 19767742

DOI: 10.1038/ncb1964

PubMed ID: 19366662

Title: Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation.

PubMed ID: 19366662

DOI: 10.1073/pnas.0809131106

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 29887380

Title: A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits.

PubMed ID: 29887380

DOI: 10.1016/j.cell.2018.05.020

PubMed ID: 16531231

Title: The structural basis of actin interaction with multiple WH2/beta-thymosin motif-containing proteins.

PubMed ID: 16531231

DOI: 10.1016/j.str.2005.12.011

PubMed ID: 22847007

Title: Interactions of isolated C-terminal fragments of neural Wiskott-Aldrich syndrome protein (N-WASP) with actin and Arp2/3 complex.

PubMed ID: 22847007

DOI: 10.1074/jbc.m112.394361

PubMed ID: 22921828

Title: Enterohaemorrhagic Escherichia coli exploits a tryptophan switch to hijack host f-actin assembly.

PubMed ID: 22921828

DOI: 10.1016/j.str.2012.07.015

PubMed ID: 24332715

Title: Structural details of human tuba recruitment by InlC of Listeria monocytogenes elucidate bacterial cell-cell spreading.

PubMed ID: 24332715

DOI: 10.1016/j.str.2013.10.017

Sequence Information:

  • Length: 505
  • Mass: 54827
  • Checksum: B5895C6055E23049
  • Sequence:
  • MSSVQQQPPP PRRVTNVGSL LLTPQENESL FTFLGKKCVT MSSAVVQLYA ADRNCMWSKK 
    CSGVACLVKD NPQRSYFLRI FDIKDGKLLW EQELYNNFVY NSPRGYFHTF AGDTCQVALN 
    FANEEEAKKF RKAVTDLLGR RQRKSEKRRD PPNGPNLPMA TVDIKNPEIT TNRFYGPQVN 
    NISHTKEKKK GKAKKKRLTK ADIGTPSNFQ HIGHVGWDPN TGFDLNNLDP ELKNLFDMCG 
    ISEAQLKDRE TSKVIYDFIE KTGGVEAVKN ELRRQAPPPP PPSRGGPPPP PPPPHNSGPP 
    PPPARGRGAP PPPPSRAPTA APPPPPPSRP SVAVPPPPPN RMYPPPPPAL PSSAPSGPPP 
    PPPSVLGVGP VAPPPPPPPP PPPGPPPPPG LPSDGDHQVP TTAGNKAALL DQIREGAQLK 
    KVEQNSRPVS CSGRDALLDQ IRQGIQLKSV ADGQESTPPT PAPTSGIVGA LMEVMQKRSK 
    AIHSSDEDED EDDEEDFEDD DEWED

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.