Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 31.6586
Cell Significance Index: -8.0300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 18.1658
Cell Significance Index: -7.3800 - Cell Name: basophilic erythroblast (CL0000549)
Fold Change: 11.0451
Cell Significance Index: 5.0300 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 7.7236
Cell Significance Index: 47.9900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 5.8031
Cell Significance Index: -7.1600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.8811
Cell Significance Index: 76.9300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 2.1135
Cell Significance Index: -8.3400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.4833
Cell Significance Index: 39.7500 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 1.1063
Cell Significance Index: 15.3500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.8417
Cell Significance Index: 83.2600 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.6400
Cell Significance Index: 5.4400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.5919
Cell Significance Index: 30.7500 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.5859
Cell Significance Index: 6.3700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5678
Cell Significance Index: 34.0900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5377
Cell Significance Index: 24.3700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 0.5163
Cell Significance Index: -1.1300 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.4557
Cell Significance Index: 3.0300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4254
Cell Significance Index: 46.2700 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.3894
Cell Significance Index: 5.5800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3584
Cell Significance Index: 58.2900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2999
Cell Significance Index: 8.6400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.2990
Cell Significance Index: 4.0800 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.2842
Cell Significance Index: 4.0700 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.2210
Cell Significance Index: 2.0400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.1640
Cell Significance Index: 5.7000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.1623
Cell Significance Index: 18.9100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1305
Cell Significance Index: 24.8300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1269
Cell Significance Index: 2.7500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1241
Cell Significance Index: 8.5900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1196
Cell Significance Index: 107.9800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1154
Cell Significance Index: 63.0200 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.1083
Cell Significance Index: 1.5200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0999
Cell Significance Index: 69.0800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0924
Cell Significance Index: 18.5300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0924
Cell Significance Index: 33.1300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0916
Cell Significance Index: 16.5100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0892
Cell Significance Index: 17.7100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0743
Cell Significance Index: 9.5200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0467
Cell Significance Index: 5.7400 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.0459
Cell Significance Index: 0.9600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0420
Cell Significance Index: 4.9500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0356
Cell Significance Index: 1.2500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0265
Cell Significance Index: 0.7400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0199
Cell Significance Index: 8.7900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0160
Cell Significance Index: 0.3400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0114
Cell Significance Index: 0.2900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0094
Cell Significance Index: 0.3000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0025
Cell Significance Index: -4.7000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0027
Cell Significance Index: -0.1400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0036
Cell Significance Index: -0.0600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0048
Cell Significance Index: -8.8000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0050
Cell Significance Index: -0.6900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0060
Cell Significance Index: -9.1600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0074
Cell Significance Index: -10.0900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0102
Cell Significance Index: -7.4800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0106
Cell Significance Index: -6.7300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0106
Cell Significance Index: -8.0000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0125
Cell Significance Index: -9.2500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0152
Cell Significance Index: -9.4800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0155
Cell Significance Index: -8.7500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0162
Cell Significance Index: -7.3700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0206
Cell Significance Index: -5.9200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0301
Cell Significance Index: -5.1400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0362
Cell Significance Index: -4.6800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0386
Cell Significance Index: -2.7300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0413
Cell Significance Index: -6.0000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0421
Cell Significance Index: -1.9800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0426
Cell Significance Index: -1.1400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0449
Cell Significance Index: -9.4600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0474
Cell Significance Index: -4.8500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0536
Cell Significance Index: -2.5000 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: -0.0611
Cell Significance Index: -0.5800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0666
Cell Significance Index: -7.6300 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.0714
Cell Significance Index: -1.0700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0731
Cell Significance Index: -4.4800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0747
Cell Significance Index: -4.8200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0763
Cell Significance Index: -5.1300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0776
Cell Significance Index: -8.0800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0831
Cell Significance Index: -6.3800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0859
Cell Significance Index: -6.4000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0995
Cell Significance Index: -4.4000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0998
Cell Significance Index: -5.6000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1014
Cell Significance Index: -8.0300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1066
Cell Significance Index: -6.7200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1106
Cell Significance Index: -4.1900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1128
Cell Significance Index: -2.9000 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.1150
Cell Significance Index: -5.8100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1177
Cell Significance Index: -7.2400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1185
Cell Significance Index: -6.1700 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1219
Cell Significance Index: -4.9900 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.1308
Cell Significance Index: -2.2000 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.1441
Cell Significance Index: -2.8500 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.1456
Cell Significance Index: -2.3100 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.1480
Cell Significance Index: -2.2300 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1517
Cell Significance Index: -3.2200 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1559
Cell Significance Index: -3.1300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1572
Cell Significance Index: -4.2800 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1590
Cell Significance Index: -4.1800 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1605
Cell Significance Index: -4.1000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1608
Cell Significance Index: -5.1200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1423766307
Symbol: CCNE1_HUMAN
Name: G1/S-specific cyclin-E1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1833066
Title: Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast.
PubMed ID: 1833066
PubMed ID: 1833068
Title: Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.
PubMed ID: 1833068
PubMed ID: 7739542
Title: Human cyclin E, a nuclear protein essential for the G1-to-S phase transition.
PubMed ID: 7739542
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8649818
Title: Regulation of cyclin E transcription by E2Fs and retinoblastoma protein.
PubMed ID: 8649818
PubMed ID: 8833152
Title: Molecular cloning and chromosomal localization of the human cyclin C (CCNC) and cyclin E (CCNE) genes: deletion of the CCNC gene in human tumors.
PubMed ID: 8833152
PubMed ID: 8207080
PubMed ID: 8861947
Title: Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E.
PubMed ID: 8861947
PubMed ID: 9840943
Title: Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins.
PubMed ID: 9840943
PubMed ID: 14536078
Title: Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation.
PubMed ID: 14536078
PubMed ID: 15178429
Title: NIRF induces G1 arrest and associates with Cdk2.
PubMed ID: 15178429
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 21952639
Title: NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor.
PubMed ID: 21952639
PubMed ID: 21540187
Title: Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling.
PubMed ID: 21540187
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 15660127
Title: The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles.
PubMed ID: 15660127
PubMed ID: 17434132
Title: Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
PubMed ID: 17434132
Sequence Information:
- Length: 410
- Mass: 47077
- Checksum: 424DF0B253B7047E
- Sequence:
MPRERRERDA KERDTMKEDG GAEFSARSRK RKANVTVFLQ DPDEEMAKID RTARDQCGSQ PWDNNAVCAD PCSLIPTPDK EDDDRVYPNS TCKPRIIAPS RGSPLPVLSW ANREEVWKIM LNKEKTYLRD QHFLEQHPLL QPKMRAILLD WLMEVCEVYK LHRETFYLAQ DFFDRYMATQ ENVVKTLLQL IGISSLFIAA KLEEIYPPKL HQFAYVTDGA CSGDEILTME LMIMKALKWR LSPLTIVSWL NVYMQVAYLN DLHEVLLPQY PQQIFIQIAE LLDLCVLDVD CLEFPYGILA ASALYHFSSS ELMQKVSGYQ WCDIENCVKW MVPFAMVIRE TGSSKLKHFR GVADEDAHNI QTHRDSLDLL DKARAKKAML SEQNRASPLP SGLLTPPQSG KKQSSGPEMA
Genular Protein ID: 165218448
Symbol: A0A0G3DHS8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 26004630
Title: Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming.
PubMed ID: 26004630
Sequence Information:
- Length: 365
- Mass: 41739
- Checksum: AFD3B387393832C3
- Sequence:
MPRERRERDA KERDTMKEDG GAEFSARSRK RKANVTVFLQ DPDEEMAKID RTARDQCGSQ PWDNNAVCAD PCSLIPTPDK EDDDRVYPNS TCKPRIIAPS RGSPLPVLSW ANREEVWKIM LNKEKTYLRD QHFLEQHPLL QPKMRAILLD WLMEVCEVYK LHRETFYLAQ DFFDRYMATQ ENVVKTLLQL IGISSLFIAA KLEEIYPPKL HQFAYVTDGA CSGDEILTME LMIMKLLDLC VLDVDCLEFP YGILAASALY HFSSSELMQK VSGYQWCDIE NCVKWMVPFA MVIRETGSSK LKHFRGVADE DAHNIQTHRD SLDLLDKARA KKAMLSEQNR ASPLPSGLLT PPQSGKKQSS GPEMA
Genular Protein ID: 3296212702
Symbol: V5W5X2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 361
- Mass: 41338
- Checksum: 51C33D1092AEBF7C
- Sequence:
MPRERRERDA KERDTMKEDG GAEFSARSRK RKANVTVFLQ DPDEEMAKID RTARDQCGSQ PWDNNAVCAD PCSLIPTPDK EDDDRVYPNS TCKPRIIAPS RGSPLPVLSW ANREEVWKIM LNKEKTYLRD QHFLEQHPLL QPKMRAILLD WLMEEIYPPK LHQFAYVTDG ACSGDEILTM ELMIMKALKW RLSPLTIVSW LNVYMQVAYL NDLHEVLLPQ YPQQIFIQIA ELLDLCVLDV DCLEFPYGIL AASALYHFSS SELMQKVSGY QWCDIENCVK WMVPFAMVIR ETGSSKLKHF RGVADEDAHN IQTHRDSLDL LDKARAKKAM LSEQNRASPL PSGLLTPPQS GKKQSSGPEM A
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.