Details for: PLOD3

Gene ID: 8985

Symbol: PLOD3

Ensembl ID: ENSG00000106397

Description: procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

Associated with

Other Information

Genular Protein ID: 2944290721

Symbol: PLOD3_HUMAN

Name: Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9582318

Title: Primary structure, tissue distribution, and chromosomal localization of a novel isoform of lysyl hydroxylase (lysyl hydroxylase 3).

PubMed ID: 9582318

DOI: 10.1074/jbc.273.21.12881

PubMed ID: 9724729

Title: Cloning and characterization of a third human lysyl hydroxylase isoform.

PubMed ID: 9724729

DOI: 10.1073/pnas.95.18.10482

PubMed ID: 10686427

Title: Complete exon-intron organization of the gene for human lysyl hydroxylase 3 (LH3).

PubMed ID: 10686427

DOI: 10.1016/s0945-053x(99)00058-x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10934207

Title: Lysyl hydroxylase 3 is a multifunctional protein possessing collagen glucosyltransferase activity.

PubMed ID: 10934207

DOI: 10.1074/jbc.m006203200

PubMed ID: 11896059

Title: Identification of amino acids important for the catalytic activity of the collagen glucosyltransferase associated with the multifunctional lysyl hydroxylase 3 (LH3).

PubMed ID: 11896059

DOI: 10.1074/jbc.m201389200

PubMed ID: 11956192

Title: Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity.

PubMed ID: 11956192

DOI: 10.1074/jbc.m112077200

PubMed ID: 12475640

Title: The third activity for lysyl hydroxylase 3: galactosylation of hydroxylysyl residues in collagens in vitro.

PubMed ID: 12475640

DOI: 10.1016/s0945-053x(02)00071-9

PubMed ID: 18298658

Title: The glycosyltransferase activities of lysyl hydroxylase 3 (LH3) in the extracellular space are important for cell growth and viability.

PubMed ID: 18298658

DOI: 10.1111/j.1582-4934.2008.00286.x

PubMed ID: 20470363

Title: The human collagen beta(1-O)galactosyltransferase, GLT25D1, is a soluble endoplasmic reticulum localized protein.

PubMed ID: 20470363

DOI: 10.1186/1471-2121-11-33

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21465473

Title: Lysyl hydroxylase 3 is secreted from cells by two pathways.

PubMed ID: 21465473

DOI: 10.1002/jcp.22774

PubMed ID: 25419660

Title: Lysyl hydroxylase 3 modifies lysine residues to facilitate oligomerization of mannan-binding lectin.

PubMed ID: 25419660

DOI: 10.1371/journal.pone.0113498

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 30089812

Title: Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.

PubMed ID: 30089812

DOI: 10.1038/s41467-018-05631-5

PubMed ID: 18834968

Title: A connective tissue disorder caused by mutations of the lysyl hydroxylase 3 gene.

PubMed ID: 18834968

DOI: 10.1016/j.ajhg.2008.09.004

PubMed ID: 30237576

Title: Autozygome and high throughput confirmation of disease genes candidacy.

PubMed ID: 30237576

DOI: 10.1038/s41436-018-0138-x

Sequence Information:

  • Length: 738
  • Mass: 84785
  • Checksum: 08424B46985941F9
  • Sequence:
  • MTSSGPGPRF LLLLPLLLPP AASASDRPRG RDPVNPEKLL VITVATAETE GYLRFLRSAE 
    FFNYTVRTLG LGEEWRGGDV ARTVGGGQKV RWLKKEMEKY ADREDMIIMF VDSYDVILAG 
    SPTELLKKFV QSGSRLLFSA ESFCWPEWGL AEQYPEVGTG KRFLNSGGFI GFATTIHQIV 
    RQWKYKDDDD DQLFYTRLYL DPGLREKLSL NLDHKSRIFQ NLNGALDEVV LKFDRNRVRI 
    RNVAYDTLPI VVHGNGPTKL QLNYLGNYVP NGWTPEGGCG FCNQDRRTLP GGQPPPRVFL 
    AVFVEQPTPF LPRFLQRLLL LDYPPDRVTL FLHNNEVFHE PHIADSWPQL QDHFSAVKLV 
    GPEEALSPGE ARDMAMDLCR QDPECEFYFS LDADAVLTNL QTLRILIEEN RKVIAPMLSR 
    HGKLWSNFWG ALSPDEYYAR SEDYVELVQR KRVGVWNVPY ISQAYVIRGD TLRMELPQRD 
    VFSGSDTDPD MAFCKSFRDK GIFLHLSNQH EFGRLLATSR YDTEHLHPDL WQIFDNPVDW 
    KEQYIHENYS RALEGEGIVE QPCPDVYWFP LLSEQMCDEL VAEMEHYGQW SGGRHEDSRL 
    AGGYENVPTV DIHMKQVGYE DQWLQLLRTY VGPMTESLFP GYHTKARAVM NFVVRYRPDE 
    QPSLRPHHDS STFTLNVALN HKGLDYEGGG CRFLRYDCVI SSPRKGWALL HPGRLTHYHE 
    GLPTTWGTRY IMVSFVDP

Genular Protein ID: 732421841

Symbol: Q9UG85_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 365
  • Mass: 42395
  • Checksum: 044726CD02AB83C0
  • Sequence:
  • GAMDLCRQDP ECEFYFSLDA DAVLTNLQTL RILIEENRKV IAPMLSRHGK LWSNFWGALS 
    PDEYYARSED YVELVQRKRV GVWNVPYISQ AYVIRGDTLR MELPQRDVFS GSDTDPDMAF 
    CKSFRDKGIF LHLSNQHEFG RLLATSRYDT EHLHPDLWQI FDNPVGWKEQ YIHENYSRAL 
    EGEGIVEQPC PDVYWFPLLS EQMCDELVAE MEHYGQWSGG RHEDSRLAGG YENVPTVDIH 
    MKQVGYEDQW LQLLRTYVGP MTESLFPGYH TKARAVMNFV VRYRPDEQPS LRPHHDSSTF 
    TLNVALNHKG LDYEGGGCRF LRYDCVISSP RKGWALLHPG RLTHYHEGLP TTWGTRYIMV 
    SFVDP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.