Details for: RPS6KA4

Gene ID: 8986

Symbol: RPS6KA4

Ensembl ID: ENSG00000162302

Description: ribosomal protein S6 kinase A4

Associated with

Other Information

Genular Protein ID: 795658356

Symbol: KS6A4_HUMAN

Name: Ribosomal protein S6 kinase alpha-4

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9792677

Title: RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK).

PubMed ID: 9792677

DOI: 10.1074/jbc.273.45.29661

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 9687510

Title: Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.

PubMed ID: 9687510

DOI: 10.1093/emboj/17.15.4426

PubMed ID: 11035004

Title: C-terminal elements control location, activation threshold, and p38 docking of ribosomal S6 kinase B (RSKB).

PubMed ID: 11035004

DOI: 10.1074/jbc.m005822200

PubMed ID: 12773393

Title: MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14.

PubMed ID: 12773393

DOI: 10.1093/emboj/cdg273

PubMed ID: 18508628

Title: MSK activation and physiological roles.

PubMed ID: 18508628

DOI: 10.2741/3122

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19464896

Title: The versatile role of MSKs in transcriptional regulation.

PubMed ID: 19464896

DOI: 10.1016/j.tibs.2009.02.007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 772
  • Mass: 85606
  • Checksum: 3606209693D0B5F3
  • Sequence:
  • MGDEDDDESC AVELRITEAN LTGHEEKVSV ENFELLKVLG TGAYGKVFLV RKAGGHDAGK 
    LYAMKVLRKA ALVQRAKTQE HTRTERSVLE LVRQAPFLVT LHYAFQTDAK LHLILDYVSG 
    GEMFTHLYQR QYFKEAEVRV YGGEIVLALE HLHKLGIIYR DLKLENVLLD SEGHIVLTDF 
    GLSKEFLTEE KERTFSFCGT IEYMAPEIIR SKTGHGKAVD WWSLGILLFE LLTGASPFTL 
    EGERNTQAEV SRRILKCSPP FPPRIGPVAQ DLLQRLLCKD PKKRLGAGPQ GAQEVRNHPF 
    FQGLDWVALA ARKIPAPFRP QIRSELDVGN FAEEFTRLEP VYSPPGSPPP GDPRIFQGYS 
    FVAPSILFDH NNAVMTDGLE APGAGDRPGR AAVARSAMMQ DSPFFQQYEL DLREPALGQG 
    SFSVCRRCRQ RQSGQEFAVK ILSRRLEANT QREVAALRLC QSHPNVVNLH EVHHDQLHTY 
    LVLELLRGGE LLEHIRKKRH FSESEASQIL RSLVSAVSFM HEEAGVVHRD LKPENILYAD 
    DTPGAPVKII DFGFARLRPQ SPGVPMQTPC FTLQYAAPEL LAQQGYDESC DLWSLGVILY 
    MMLSGQVPFQ GASGQGGQSQ AAEIMCKIRE GRFSLDGEAW QGVSEEAKEL VRGLLTVDPA 
    KRLKLEGLRG SSWLQDGSAR SSPPLRTPDV LESSGPAVRS GLNATFMAFN RGKREGFFLK 
    SVENAPLAKR RKQKLRSATA SRRGSPAPAN PGRAPVASKG APRRANGPLP PS

Genular Protein ID: 3781688554

Symbol: A0PJF8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 556
  • Mass: 62491
  • Checksum: 4BEE746B400B9D92
  • Sequence:
  • MGDEDDDESC AVELRITEAN LTGHEEKVSV ENFELLKVLG TGAYGKVFLV RKAGGHDAGK 
    LYAMKVLRKA ALVQRAKTQE HTRTERSVLE LVRQAPFLVT LHYAFQTDAK LHLILDYVSG 
    GEMFTHLYQR QYFKEAEVRV YGGEIVLALE HLHKLGIIYR DLKLENVLLD SEGHIVLTDF 
    GLSKEFLTEE KERTFSFCGT IEYMAPEIIR SKTGHGKAVD WWSLGILLFE LLTGASPFTL 
    EGERNTQAEV SRRILKCSPP FPPRIGPVAQ DLLQRLLCKD PKKRLGAGPQ GAQEVRNHPF 
    FQGLDWVALA ARKIPAPFRP QIRSELDVGN FAEEFTRLEP VYSPPGSPPP GDPRIFQGYS 
    FVAPSILFDH NNAVMTDGLE APGAGDRPGR AAVARSAMMQ DSPFFQQYEL DLREPALGQG 
    SFSVCRRCRQ RQSGQEFAVK ILSRRLEANT QREVAALRLC QSHPNVVNLH EVHHDQLHTY 
    LVLELLRGGE LLEHIRKKRH FSESEASQIL RSLVSAVSFM HEEAGVVHRD LKPENILYAD 
    DTPGAPVKII DFGFAR

Genular Protein ID: 2858718468

Symbol: B4DPV1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 709
  • Mass: 78796
  • Checksum: 2C3305FC03BE7BDE
  • Sequence:
  • MKVLRKAALV QRAKTQEHTR TERSVLELVR QAPFLVTLHY AFQTDAKLHL ILDYVSGGEM 
    FTHLYQRQYF KEAEVRVYGG EIVLALEHLH KLGIIYRDLK LENVLLDSEG HIVLTDFGLS 
    KEFLTEEKER TFSFCGTIEY MAPEIIRSKT GHGKAVDWWS LGILLFELLT GASPFTLEGE 
    RNTQAEVSRR ILKCSPPFPP RIGPVAQDLL QRLLCKDPKK RLGAGPQGAQ EVRNHPFFQG 
    LDWVALAARK IPAPFRPQIR SELDVGNFAE EFTRLEPVYS PPGSPPPGDP RIFQGYSFVA 
    PSILFDHNNA VMTDGLEAPG AGDRPGRAAV ARSAMMQDSP FFQQYELDLR EPALGQGSFS 
    VCRRCRQRQS GQEFAVKILS RRLEANTQRE VAGLRLCQSH PNVVNLHEVH HDQLHTYLVL 
    ELLRGGELLE HIRKKRHFSE SEASQILRSL VSAVSFMHEE AGVVHRDLKP ENILYADDTP 
    GAPVKIIDFG FARLRPQSPG VPMQTPCFTL QYAAPELLAQ QGYDESCDLW SLGVILYMML 
    SGQVPFQGAS GQGGQSQAAE IMCKIREGRF SLDGEAWQGV SEEAKELVRG LLTVDPAKRL 
    KLEGLRGSSW LQDGSARSSP PLRTPDVLES SGPAVRSGLN ATFMAFNRGK REGFFLKSVE 
    NAPLAKRRKQ KLRSATASRR GSPAPANPGR APVAAKGAPR RANGPLPPS

Genular Protein ID: 4038901424

Symbol: E9PJN1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 765
  • Mass: 84756
  • Checksum: 4CB87B934C79D550
  • Sequence:
  • MGDEDDDESC AVELRITEAN LTGHEEKVSV ENFELLKVLG TGAYGKVFLV RKAGGHDAGK 
    LYAMKVLRKA ALVQRAKTQE HTRTERSVLE LVRQAPFLVT LHYAFQTDAK LHLILDYVSG 
    GEMFTHLYQR QYFKEAEVRV YGGEIVLALE HLHKLGIIYR DLKLENVLLD SEGHIVLTDF 
    GLSKEFLTEE KERTFSFCGT IEYMAPEIIR SKTGHGKAVD WWSLGILLFE LLTGASPFTL 
    EGERNTQAEV SRRILKCSPP FPPRIGPVAQ DLLQRLLCKD PKKRLGAGPQ GAQEVRNHPF 
    FQGLDWVALA ARKIPAPFRP QIRSELDVGN FAEEFTRLEP VYSPPGSPPP GDPRIFQGYS 
    FVAPSILFDH NNAVMTDGLE APGAGDRPGR AAVARSAMMQ YELDLREPAL GQGSFSVCRR 
    CRQRQSGQEF AVKILSRRLE ANTQREVAAL RLCQSHPNVV NLHEVHHDQL HTYLVLELLR 
    GGELLEHIRK KRHFSESEAS QILRSLVSAV SFMHEEAGVV HRDLKPENIL YADDTPGAPV 
    KIIDFGFARL RPQSPGVPMQ TPCFTLQYAA PELLAQQGYD ESCDLWSLGV ILYMMLSGQV 
    PFQGASGQGG QSQAAEIMCK IREGRFSLDG EAWQGVSEEA KELVRGLLTV DPAKRLKLEG 
    LRGSSWLQDG SARSSPPLRT PDVLESSGPA VRSGLNATFM AFNRGKREGF FLKSVENAPL 
    AKRRKQKLRS ATASRRGSPA PANPGRAPVA SKGAPRRANG PLPPS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.