Details for: CCNF

Gene ID: 899

Symbol: CCNF

Ensembl ID: ENSG00000162063

Description: cyclin F

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 30.5153
    Cell Significance Index: -7.7400
  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 18.9013
    Cell Significance Index: -2.9400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 17.1074
    Cell Significance Index: -6.9500
  • Cell Name: sebaceous gland cell (CL2000021)
    Fold Change: 8.1387
    Cell Significance Index: 10.5300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 6.1884
    Cell Significance Index: -7.6300
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 3.6969
    Cell Significance Index: 60.9200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 2.9266
    Cell Significance Index: -7.8400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 2.4729
    Cell Significance Index: 151.6100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.7142
    Cell Significance Index: 15.2100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6380
    Cell Significance Index: 17.8300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5436
    Cell Significance Index: 107.8700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5350
    Cell Significance Index: 87.0100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.4755
    Cell Significance Index: 16.7100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4241
    Cell Significance Index: 46.1300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4175
    Cell Significance Index: 21.6900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3656
    Cell Significance Index: 73.3400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3061
    Cell Significance Index: 36.1000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2835
    Cell Significance Index: 255.9700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2757
    Cell Significance Index: 27.2800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2360
    Cell Significance Index: 84.6500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2318
    Cell Significance Index: 13.0100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.2137
    Cell Significance Index: 2.6500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.1967
    Cell Significance Index: 4.0800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1927
    Cell Significance Index: 13.6300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1750
    Cell Significance Index: 12.1100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1676
    Cell Significance Index: 3.6700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1614
    Cell Significance Index: 29.1000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1527
    Cell Significance Index: 17.8000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.1072
    Cell Significance Index: 3.0600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1023
    Cell Significance Index: 19.4600
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 0.1020
    Cell Significance Index: 0.2300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0857
    Cell Significance Index: 5.2700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0842
    Cell Significance Index: 37.2300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.0771
    Cell Significance Index: 0.7100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0717
    Cell Significance Index: 8.8200
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: 0.0676
    Cell Significance Index: 0.8400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0664
    Cell Significance Index: 1.6600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0621
    Cell Significance Index: 33.9200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0611
    Cell Significance Index: 1.7600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0568
    Cell Significance Index: 1.8200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0504
    Cell Significance Index: 1.3500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0478
    Cell Significance Index: 33.0600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0466
    Cell Significance Index: 1.0100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0442
    Cell Significance Index: 2.9700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0292
    Cell Significance Index: 4.2500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0280
    Cell Significance Index: 1.4700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0193
    Cell Significance Index: 0.3300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0130
    Cell Significance Index: 24.4600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0113
    Cell Significance Index: 1.5500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0099
    Cell Significance Index: 15.2000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0077
    Cell Significance Index: 0.2700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0040
    Cell Significance Index: 7.3500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0036
    Cell Significance Index: 2.2700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0024
    Cell Significance Index: 3.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0024
    Cell Significance Index: -0.1100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0052
    Cell Significance Index: -0.2400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0084
    Cell Significance Index: -6.3700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0087
    Cell Significance Index: -6.3500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0109
    Cell Significance Index: -4.9300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0113
    Cell Significance Index: -0.5000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0115
    Cell Significance Index: -8.5200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0142
    Cell Significance Index: -0.3400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0145
    Cell Significance Index: -8.1500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0148
    Cell Significance Index: -0.5600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0179
    Cell Significance Index: -1.1600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0199
    Cell Significance Index: -2.5500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0207
    Cell Significance Index: -5.9600
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0304
    Cell Significance Index: -0.3300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0349
    Cell Significance Index: -5.9600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0394
    Cell Significance Index: -0.6600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0400
    Cell Significance Index: -2.4000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0416
    Cell Significance Index: -2.6200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0416
    Cell Significance Index: -8.7600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0425
    Cell Significance Index: -4.3400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0443
    Cell Significance Index: -5.0800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0457
    Cell Significance Index: -1.2200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0458
    Cell Significance Index: -2.3900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0520
    Cell Significance Index: -6.7200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0529
    Cell Significance Index: -4.0600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0540
    Cell Significance Index: -1.1300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0723
    Cell Significance Index: -7.5300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0747
    Cell Significance Index: -1.0700
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0755
    Cell Significance Index: -1.2700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0806
    Cell Significance Index: -6.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0836
    Cell Significance Index: -3.9300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0864
    Cell Significance Index: -2.3100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0942
    Cell Significance Index: -7.4600
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0952
    Cell Significance Index: -1.5100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0999
    Cell Significance Index: -2.7200
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.1098
    Cell Significance Index: -1.6700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1177
    Cell Significance Index: -3.7500
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.1177
    Cell Significance Index: -1.6500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1239
    Cell Significance Index: -1.6900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1286
    Cell Significance Index: -4.2100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1331
    Cell Significance Index: -3.4000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1386
    Cell Significance Index: -2.7400
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.1389
    Cell Significance Index: -1.9900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1423
    Cell Significance Index: -3.0200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.1432
    Cell Significance Index: -0.9700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1444
    Cell Significance Index: -3.1200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cell Cycle Regulation:** Cyclin F is a G2/M phase cyclin that interacts with cyclin-dependent kinases (CDKs) to regulate cell cycle progression. It has been shown to bind to CDK1 and CDK2, inhibiting their activity and preventing premature entry into mitosis. 2. **Immune Response Regulation:** Cyclin F has been implicated in the regulation of immune responses, particularly in the adaptive immune system. It has been shown to interact with proteins involved in antigen processing and presentation, such as major histocompatibility complex (MHC) class I molecules. 3. **Ubiquitination and Proteasome Degradation:** Cyclin F has been shown to participate in the ubiquitination and proteasome degradation of proteins, regulating protein turnover and cell cycle progression. 4. **Neddylation and SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process:** Cyclin F has been implicated in the neddylation of proteins, a post-translational modification that regulates protein stability and degradation. **Pathways and Functions:** 1. **Adaptive Immune System:** Cyclin F has been implicated in the regulation of immune responses, particularly in the adaptive immune system. It interacts with proteins involved in antigen processing and presentation, such as MHC class I molecules. 2. **Cell Division:** Cyclin F regulates cell cycle progression, specifically during the G2/M phase, by interacting with CDKs and inhibiting their activity. 3. **Protein Binding and Modification:** Cyclin F participates in protein binding and modification, including ubiquitination, neddylation, and proteasome degradation. 4. **Mitotic Cell Cycle Phase Transition:** Cyclin F regulates the transition from mitosis to the G1 phase of the cell cycle. **Clinical Significance:** 1. **Cancer:** Dysregulation of cyclin F has been implicated in various cancers, including breast, lung, and colon cancer. Overexpression or mutation of cyclin F may contribute to tumorigenesis and cancer progression. 2. **Immune-Mediated Diseases:** Dysregulation of cyclin F has been implicated in immune-mediated diseases, including autoimmune disorders and inflammatory conditions. 3. **Neurological Disorders:** Cyclin F has been implicated in the regulation of neuronal development and function, and dysregulation of cyclin F has been linked to neurological disorders, including neurodegenerative diseases. 4. **Developmental Biology:** Cyclin F plays a crucial role in the development of various tissues, including the kidney, heart, and brain. In conclusion, cyclin F is a multifunctional protein that plays a critical role in regulating the cell cycle and immune response. Its dysregulation has been implicated in various diseases, including cancer, immune-mediated disorders, and neurological disorders. Further research is needed to fully understand the mechanisms of cyclin F regulation and its clinical significance.

Genular Protein ID: 2569007661

Symbol: CCNF_HUMAN

Name: Cyclin-F

UniProtKB Accession Codes:

P41002 B2R8H3 Q96EG9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 1 ExpressionAtlas 1 GO 19 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7813445

Title: Human cyclin F.

PubMed ID: 7813445

DOI: 10.1002/j.1460-2075.1994.tb06955.x

PubMed ID: 7896286

Title: A novel cyclin gene (CCNF) in the region of the polycystic kidney disease gene (PKD1).

PubMed ID: 7896286

DOI: 10.1006/geno.1994.1578

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8706131

Title: SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box.

PubMed ID: 8706131

DOI: 10.1016/s0092-8674(00)80098-7

PubMed ID: 10716937

Title: Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction.

PubMed ID: 10716937

DOI: 10.1093/emboj/19.6.1378

PubMed ID: 12122006

Title: Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins.

PubMed ID: 12122006

DOI: 10.1074/jbc.m205503200

PubMed ID: 20596027

Title: SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation.

PubMed ID: 20596027

DOI: 10.1038/nature09140

PubMed ID: 22632967

Title: Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair.

PubMed ID: 22632967

DOI: 10.1016/j.cell.2012.03.043

PubMed ID: 22441691

Title: Neurl4, a novel daughter centriole protein, prevents formation of ectopic microtubule organizing centres.

PubMed ID: 22441691

DOI: 10.1038/embor.2012.40

PubMed ID: 25557911

Title: Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control.

PubMed ID: 25557911

DOI: 10.1038/ncomms6800

PubMed ID: 27653696

Title: APC/C and SCF(cyclin F) Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry.

PubMed ID: 27653696

DOI: 10.1016/j.celrep.2016.08.058

PubMed ID: 26818844

Title: SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication.

PubMed ID: 26818844

DOI: 10.1038/ncomms10530

PubMed ID: 27080313

Title: CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia.

PubMed ID: 27080313

DOI: 10.1038/ncomms11253

PubMed ID: 28852778

Title: Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy.

PubMed ID: 28852778

DOI: 10.1007/s00018-017-2632-8

Sequence Information:

  • Length: 786
  • Mass: 87640
  • Checksum: ADB2FE41BC708898
  • Sequence:
    • MGSGGVVHCR CAKCFCYPTK RRIRRRPRNL TILSLPEDVL FHILKWLSVE DILAVRAVHS 
QLKDLVDNHA SVWACASFQE LWPSPGNLKL FERAAEKGNF EAAVKLGIAY LYNEGLSVSD 
EARAEVNGLK ASRFFSLAER LNVGAAPFIW LFIRPPWSVS GSCCKAVVHE SLRAECQLQR 
THKASILHCL GRVLSLFEDE EKQQQAHDLF EEAAHQGCLT SSYLLWESDR RTDVSDPGRC 
LHSFRKLRDY AAKGCWEAQL SLAKACANAN QLGLEVRASS EIVCQLFQAS QAVSKQQVFS 
VQKGLNDTMR YILIDWLVEV ATMKDFTSLC LHLTVECVDR YLRRRLVPRY RLQLLGIACM 
VICTRFISKE ILTIREAVWL TDNTYKYEDL VRMMGEIVSA LEGKIRVPTV VDYKEVLLTL 
VPVELRTQHL CSFLCELSLL HTSLSAYAPA RLAAAALLLA RLTHGQTQPW TTQLWDLTGF 
SYEDLIPCVL SLHKKCFHDD APKDYRQVSL TAVKQRFEDK RYGEISQEEV LSYSQLCAAL 
GVTQDSPDPP TFLSTGEIHA FLSSPSGRRT KRKRENSLQE DRGSFVTTPT AELSSQEETL 
LGSFLDWSLD CCSGYEGDQE SEGEKEGDVT APSGILDVTV VYLNPEQHCC QESSDEEACP 
EDKGPQDPQA LALDTQIPAT PGPKPLVRTS REPGKDVTTS GYSSVSTASP TSSVDGGLGA 
LPQPTSVLSL DSDSHTQPCH HQARKSCLQC RPPSPPESSV PQQQVKRINL CIHSEEEDMN 
LGLVRL

Genular Protein ID: 1278183797

Symbol: Q59HD0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59HD0

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 RuleBase 1 SAM 1 SMART 4 SUPFAM 1

Sequence Information:

  • Length: 701
  • Mass: 77957
  • Checksum: 0E815872CB606EC5
  • Sequence:
    • RTSWPSELAA EKGNFEAAVK LGIAYLYNEG LSVSDEARAE VNGLKASRFF SLAERLNVGA 
APFIWLFIRP PWSVSGSCCK AVVHESLRAE CQLQRTHKAS ILHCLGRVLS LFEDEEKQQQ 
AHDLFEEAAH QGCLTSSYLL WESDRRTDVS DPGRCLHSFR KLRDYAAKGC WEAQLSLAKA 
CANANQLGLE VRASSEIVCQ LFQASQAVSK QQVFSVQKGL NDTMRYILID WLVEVATMKD 
FTSLCLHLTV ECVDRYLRRR LVPRYRLQLL GIACMVICTR FISKEILTIR EAVWLTDNTY 
KYEDLVRMMG EIVSALEGKI RVPTVVDYKE VLLTLVPVEL RTQHLCSFLC ELSLLHTSLS 
AYAPARLAAA ALLLARLTHG QTQPWTTQLW DLTGFSYEDL IPCVLSLHKK CFHDDAPKDY 
RQVSLTAVKQ RFEDKRYGEI SQEEVLSYSQ LCAALGVTQD SPDPPTFLST GEIHAFLSSP 
SGRRTKRKRE NSLQEDRGSF VTTPTAELSS QEETLLGSFL DWSLDCCSGY EGDQESEGEK 
EGDVTAPSGI LDVTVVYLNP EQHCCQESSD EEACPEDKGP QDPQALALDT QIPATPGPKP 
LVRTSREPGK DVTTSGYSSV STASPTSSVD GGLGALPQPT SVLSLDSDSH TQPCHHQARK 
SFLQCRPPSP PESSVPQQQV KRINLCIHSE EEDMNLGLVR L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.