Details for: CCNF

Gene ID: 899

Symbol: CCNF

Ensembl ID: ENSG00000162063

Description: cyclin F

Associated with

Other Information

Genular Protein ID: 2569007661

Symbol: CCNF_HUMAN

Name: Cyclin-F

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7813445

Title: Human cyclin F.

PubMed ID: 7813445

DOI: 10.1002/j.1460-2075.1994.tb06955.x

PubMed ID: 7896286

Title: A novel cyclin gene (CCNF) in the region of the polycystic kidney disease gene (PKD1).

PubMed ID: 7896286

DOI: 10.1006/geno.1994.1578

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8706131

Title: SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box.

PubMed ID: 8706131

DOI: 10.1016/s0092-8674(00)80098-7

PubMed ID: 10716937

Title: Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction.

PubMed ID: 10716937

DOI: 10.1093/emboj/19.6.1378

PubMed ID: 12122006

Title: Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins.

PubMed ID: 12122006

DOI: 10.1074/jbc.m205503200

PubMed ID: 20596027

Title: SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation.

PubMed ID: 20596027

DOI: 10.1038/nature09140

PubMed ID: 22632967

Title: Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair.

PubMed ID: 22632967

DOI: 10.1016/j.cell.2012.03.043

PubMed ID: 22441691

Title: Neurl4, a novel daughter centriole protein, prevents formation of ectopic microtubule organizing centres.

PubMed ID: 22441691

DOI: 10.1038/embor.2012.40

PubMed ID: 25557911

Title: Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control.

PubMed ID: 25557911

DOI: 10.1038/ncomms6800

PubMed ID: 27653696

Title: APC/C and SCF(cyclin F) Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry.

PubMed ID: 27653696

DOI: 10.1016/j.celrep.2016.08.058

PubMed ID: 26818844

Title: SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication.

PubMed ID: 26818844

DOI: 10.1038/ncomms10530

PubMed ID: 27080313

Title: CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia.

PubMed ID: 27080313

DOI: 10.1038/ncomms11253

PubMed ID: 28852778

Title: Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy.

PubMed ID: 28852778

DOI: 10.1007/s00018-017-2632-8

Sequence Information:

  • Length: 786
  • Mass: 87640
  • Checksum: ADB2FE41BC708898
  • Sequence:
  • MGSGGVVHCR CAKCFCYPTK RRIRRRPRNL TILSLPEDVL FHILKWLSVE DILAVRAVHS 
    QLKDLVDNHA SVWACASFQE LWPSPGNLKL FERAAEKGNF EAAVKLGIAY LYNEGLSVSD 
    EARAEVNGLK ASRFFSLAER LNVGAAPFIW LFIRPPWSVS GSCCKAVVHE SLRAECQLQR 
    THKASILHCL GRVLSLFEDE EKQQQAHDLF EEAAHQGCLT SSYLLWESDR RTDVSDPGRC 
    LHSFRKLRDY AAKGCWEAQL SLAKACANAN QLGLEVRASS EIVCQLFQAS QAVSKQQVFS 
    VQKGLNDTMR YILIDWLVEV ATMKDFTSLC LHLTVECVDR YLRRRLVPRY RLQLLGIACM 
    VICTRFISKE ILTIREAVWL TDNTYKYEDL VRMMGEIVSA LEGKIRVPTV VDYKEVLLTL 
    VPVELRTQHL CSFLCELSLL HTSLSAYAPA RLAAAALLLA RLTHGQTQPW TTQLWDLTGF 
    SYEDLIPCVL SLHKKCFHDD APKDYRQVSL TAVKQRFEDK RYGEISQEEV LSYSQLCAAL 
    GVTQDSPDPP TFLSTGEIHA FLSSPSGRRT KRKRENSLQE DRGSFVTTPT AELSSQEETL 
    LGSFLDWSLD CCSGYEGDQE SEGEKEGDVT APSGILDVTV VYLNPEQHCC QESSDEEACP 
    EDKGPQDPQA LALDTQIPAT PGPKPLVRTS REPGKDVTTS GYSSVSTASP TSSVDGGLGA 
    LPQPTSVLSL DSDSHTQPCH HQARKSCLQC RPPSPPESSV PQQQVKRINL CIHSEEEDMN 
    LGLVRL

Genular Protein ID: 1278183797

Symbol: Q59HD0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 701
  • Mass: 77957
  • Checksum: 0E815872CB606EC5
  • Sequence:
  • RTSWPSELAA EKGNFEAAVK LGIAYLYNEG LSVSDEARAE VNGLKASRFF SLAERLNVGA 
    APFIWLFIRP PWSVSGSCCK AVVHESLRAE CQLQRTHKAS ILHCLGRVLS LFEDEEKQQQ 
    AHDLFEEAAH QGCLTSSYLL WESDRRTDVS DPGRCLHSFR KLRDYAAKGC WEAQLSLAKA 
    CANANQLGLE VRASSEIVCQ LFQASQAVSK QQVFSVQKGL NDTMRYILID WLVEVATMKD 
    FTSLCLHLTV ECVDRYLRRR LVPRYRLQLL GIACMVICTR FISKEILTIR EAVWLTDNTY 
    KYEDLVRMMG EIVSALEGKI RVPTVVDYKE VLLTLVPVEL RTQHLCSFLC ELSLLHTSLS 
    AYAPARLAAA ALLLARLTHG QTQPWTTQLW DLTGFSYEDL IPCVLSLHKK CFHDDAPKDY 
    RQVSLTAVKQ RFEDKRYGEI SQEEVLSYSQ LCAALGVTQD SPDPPTFLST GEIHAFLSSP 
    SGRRTKRKRE NSLQEDRGSF VTTPTAELSS QEETLLGSFL DWSLDCCSGY EGDQESEGEK 
    EGDVTAPSGI LDVTVVYLNP EQHCCQESSD EEACPEDKGP QDPQALALDT QIPATPGPKP 
    LVRTSREPGK DVTTSGYSSV STASPTSSVD GGLGALPQPT SVLSLDSDSH TQPCHHQARK 
    SFLQCRPPSP PESSVPQQQV KRINLCIHSE EEDMNLGLVR L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.