Details for: NAT1

Gene ID: 9

Symbol: NAT1

Ensembl ID: ENSG00000171428

Description: N-acetyltransferase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 29.4448
    Cell Significance Index: -4.5800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 18.8454
    Cell Significance Index: -4.7800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 11.0521
    Cell Significance Index: -4.4900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 4.1972
    Cell Significance Index: -5.1800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 1.4894
    Cell Significance Index: -3.9900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 1.1265
    Cell Significance Index: -3.4600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0969
    Cell Significance Index: 108.5100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9336
    Cell Significance Index: 843.0000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.9218
    Cell Significance Index: 19.9700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8480
    Cell Significance Index: 92.2400
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.8405
    Cell Significance Index: 13.8500
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.7481
    Cell Significance Index: 11.2100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6185
    Cell Significance Index: 100.6000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 0.5757
    Cell Significance Index: -1.2600
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.4419
    Cell Significance Index: 7.0900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4291
    Cell Significance Index: 19.4500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4258
    Cell Significance Index: 29.4500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.2879
    Cell Significance Index: 4.8500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2743
    Cell Significance Index: 54.4400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2715
    Cell Significance Index: 51.6600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2478
    Cell Significance Index: 12.8700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2145
    Cell Significance Index: 6.1800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.2008
    Cell Significance Index: 2.7400
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.1619
    Cell Significance Index: 2.3200
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.1568
    Cell Significance Index: 2.2000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1440
    Cell Significance Index: 16.7800
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.1124
    Cell Significance Index: 1.1000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1115
    Cell Significance Index: 3.5700
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.1095
    Cell Significance Index: 1.1300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0978
    Cell Significance Index: 2.2600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0873
    Cell Significance Index: 15.7400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0797
    Cell Significance Index: 4.1500
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.0706
    Cell Significance Index: 0.4600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0695
    Cell Significance Index: 1.4800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0682
    Cell Significance Index: 37.2600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0645
    Cell Significance Index: 2.2700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0525
    Cell Significance Index: 6.4500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0418
    Cell Significance Index: 4.9300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.0399
    Cell Significance Index: 1.0200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0366
    Cell Significance Index: 5.0300
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.0349
    Cell Significance Index: 0.4500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0297
    Cell Significance Index: 2.2100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0246
    Cell Significance Index: 0.6600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0246
    Cell Significance Index: 10.8900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0211
    Cell Significance Index: 2.7100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0202
    Cell Significance Index: 0.9400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0140
    Cell Significance Index: 0.1500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.0074
    Cell Significance Index: 0.0600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0069
    Cell Significance Index: 0.4900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0006
    Cell Significance Index: -1.0900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0019
    Cell Significance Index: -0.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0024
    Cell Significance Index: -4.4700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0025
    Cell Significance Index: -0.5100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0031
    Cell Significance Index: -1.9600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0035
    Cell Significance Index: -2.5700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0035
    Cell Significance Index: -5.3400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0037
    Cell Significance Index: -2.7900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0041
    Cell Significance Index: -0.0600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0042
    Cell Significance Index: -3.1500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0042
    Cell Significance Index: -5.6900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0070
    Cell Significance Index: -1.2000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0072
    Cell Significance Index: -0.2100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0076
    Cell Significance Index: -0.0700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0076
    Cell Significance Index: -1.1100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0084
    Cell Significance Index: -0.5400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0085
    Cell Significance Index: -4.7800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0090
    Cell Significance Index: -5.6000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0105
    Cell Significance Index: -4.7900
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.0122
    Cell Significance Index: -0.0700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0129
    Cell Significance Index: -4.6100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0131
    Cell Significance Index: -3.7700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0137
    Cell Significance Index: -1.4000
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0143
    Cell Significance Index: -0.2400
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.0148
    Cell Significance Index: -0.1600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0161
    Cell Significance Index: -0.4500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0203
    Cell Significance Index: -2.3200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0241
    Cell Significance Index: -0.9900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0266
    Cell Significance Index: -5.6100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0266
    Cell Significance Index: -1.3400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0272
    Cell Significance Index: -2.0900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0375
    Cell Significance Index: -4.8400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0453
    Cell Significance Index: -2.7800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0513
    Cell Significance Index: -4.0600
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.0533
    Cell Significance Index: -0.4900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0578
    Cell Significance Index: -2.7200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0590
    Cell Significance Index: -0.6700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0646
    Cell Significance Index: -4.0700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0708
    Cell Significance Index: -4.7600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0731
    Cell Significance Index: -1.9900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0822
    Cell Significance Index: -5.0500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0869
    Cell Significance Index: -1.2500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0891
    Cell Significance Index: -5.0000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0947
    Cell Significance Index: -2.7900
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.0966
    Cell Significance Index: -1.0000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0981
    Cell Significance Index: -2.0400
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.0994
    Cell Significance Index: -0.6600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1000
    Cell Significance Index: -2.5700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1006
    Cell Significance Index: -4.4500
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.1020
    Cell Significance Index: -0.7800
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.1067
    Cell Significance Index: -1.4800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Enzymatic Activity:** NAT1 is a cytosolic enzyme that catalyzes the N-acetylation of aromatic amines, resulting in the formation of N-acetyl derivatives, which are more water-soluble and easily excreted. 2. **Tissue Expression:** NAT1 is widely expressed in various tissues, including the liver, brain, heart, and gastrointestinal tract, where it plays a role in the metabolism of xenobiotics and endogenous compounds. 3. **Genetic Polymorphisms:** NAT1 exhibits polymorphic variations, which can affect its enzymatic activity and substrate specificity. These genetic differences can influence an individual's susceptibility to certain diseases and response to therapeutic agents. 4. **Substrate Specificity:** NAT1 has a broad substrate specificity, metabolizing a wide range of aromatic amines, including paracetamol, benzidine, and 2-naphthylamine. **Pathways and Functions:** 1. **Xenobiotic Metabolism:** NAT1 plays a crucial role in the metabolism of xenobiotics, including aromatic amines, which are commonly encountered in environmental pollutants and therapeutic agents. The enzyme facilitates the conjugation of these compounds, making them more water-soluble and easier to excrete. 2. **Paracetamol Metabolism:** NAT1 is involved in the metabolism of paracetamol (acetaminophen), a widely used analgesic and antipyretic agent. The enzyme catalyzes the N-acetylation of paracetamol, which is a critical step in its metabolism and excretion. 3. **Phase II Conjugation:** NAT1 is a key enzyme in the phase II conjugation pathway, which involves the conjugation of compounds to glutathione, sulfate, or glycine, resulting in their increased water solubility and elimination. 4. **Biological Oxidations:** NAT1 is also involved in the biological oxidation of certain compounds, including aromatic amines, which can lead to the formation of reactive oxygen species and DNA damage. **Clinical Significance:** 1. **Paracetamol Overdose:** NAT1 plays a critical role in the metabolism of paracetamol, and its deficiency or genetic polymorphisms can increase the risk of paracetamol overdose and liver damage. 2. **Cancer Risk:** NAT1 has been implicated in the metabolism of certain carcinogens, including aromatic amines, which can increase the risk of cancer development. 3. **Pharmacogenomics:** NAT1 genetic polymorphisms can affect an individual's response to certain therapeutic agents, including paracetamol and other aromatic amines. 4. **Environmental Health:** NAT1 is involved in the metabolism of environmental pollutants, including aromatic amines, which can have adverse effects on human health. In conclusion, NAT1 is a vital enzyme involved in the metabolism of xenobiotics, including aromatic amines and certain drugs. Its expression in various tissues and involvement in phase II conjugation and biological oxidation pathways highlight its importance in human health and disease. Further research is needed to fully elucidate the role of NAT1 in human health and disease, and to explore its potential as a biomarker for disease diagnosis and therapeutic monitoring.

Genular Protein ID: 4088468756

Symbol: ARY1_HUMAN

Name: Arylamine N-acetyltransferase 1

UniProtKB Accession Codes:

P18440 A8K4E7 O15159 O15300 Q546N1 Q96TE9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 8 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EC 2 EMBL 100 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 3 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 9 Rhea 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2340091

Title: Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression.

PubMed ID: 2340091

DOI: 10.1089/dna.1990.9.193

PubMed ID: 1968463

Title: Cloning and expression of cDNAs for polymorphic and monomorphic arylamine N-acetyltransferases from human liver.

PubMed ID: 1968463

DOI: 10.1016/s0021-9258(19)39609-7

PubMed ID: 8442668

Title: Structural heterogeneity of Caucasian N-acetyltransferase at the NAT1 gene locus.

PubMed ID: 8442668

DOI: 10.1006/abbi.1993.1116

PubMed ID: 9168895

Title: Identification of a novel allele at the human NAT1 acetyltransferase locus.

PubMed ID: 9168895

DOI: 10.1006/bbrc.1997.6501

PubMed ID: 9511183

Title: Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by C190T and G560A mutations.

PubMed ID: 9511183

DOI: 10.1097/00008571-199802000-00009

PubMed ID: 10862520

Title: Molecular analysis of the N-acetyltransferase 1 gene (NAT1*) using polymerase chain reaction-restriction fragment-single strand conformation polymorphism assay.

PubMed ID: 10862520

DOI: 10.1097/00008571-200006000-00003

PubMed ID: 16416399

Title: Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes.

PubMed ID: 16416399

DOI: 10.1086/500614

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1676262

Title: Structure and restriction fragment length polymorphism of genes for human liver arylamine N-acetyltransferases.

PubMed ID: 1676262

DOI: 10.1016/0006-291x(91)90676-x

PubMed ID: 9173883

Title: Study of the role of the highly conserved residues Arg9 and Arg64 in the catalytic function of human N-acetyltransferases NAT1 and NAT2 by site-directed mutagenesis.

PubMed ID: 9173883

DOI: 10.1042/bj3230207

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 17656365

Title: Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases.

PubMed ID: 17656365

DOI: 10.1074/jbc.m704138200

PubMed ID: 7585580

Title: Polymorphism in the N-acetyltransferase 1 (NAT1) polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue.

PubMed ID: 7585580

PubMed ID: 9511182

Title: Identification and characterization of variant alleles of human acetyltransferase NAT1 with defective function using p-aminosalicylate as an in-vivo and in-vitro probe.

PubMed ID: 9511182

DOI: 10.1097/00008571-199802000-00008

PubMed ID: 9682272

Title: Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas.

PubMed ID: 9682272

DOI: 10.1097/00008571-199806000-00009

Sequence Information:

  • Length: 290
  • Mass: 33899
  • Checksum: C015F7F3D4830107
  • Sequence:
    • MDIEAYLERI GYKKSRNKLD LETLTDILQH QIRAVPFENL NIHCGDAMDL GLEAIFDQVV 
RRNRGGWCLQ VNHLLYWALT TIGFETTMLG GYVYSTPAKK YSTGMIHLLL QVTIDGRNYI 
VDAGFGRSYQ MWQPLELISG KDQPQVPCVF RLTEENGFWY LDQIRREQYI PNEEFLHSDL 
LEDSKYRKIY SFTLKPRTIE DFESMNTYLQ TSPSSVFTSK SFCSLQTPDG VHCLVGFTLT 
HRRFNYKDNT DLIEFKTLSE EEIEKVLKNI FNISLQRKLV PKHGDRFFTI

Genular Protein ID: 219526902

Symbol: Q400J6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q400J6

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 9 GO 1 Gene3D 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 5 RuleBase 1 SUPFAM 1

Sequence Information:

  • Length: 92
  • Mass: 10628
  • Checksum: EE6E18B558D2559C
  • Sequence:
    • MDIEAYLERI GYKKSRNKLD LETLTDILQH QIRAVPFENL NIHCGDAMDL GLEAIFDQVV 
RRNRGGWCLQ VNHLLYWALT TIGFETTMLG GY

Genular Protein ID: 1510724687

Symbol: F5H5R8_HUMAN

Name: N/A

UniProtKB Accession Codes:

F5H5R8

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 2 Pfam 1 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 6 RuleBase 1 SMR 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

  • Length: 352
  • Mass: 40846
  • Checksum: 341005CE6234D94F
  • Sequence:
    • MLLLLLHKEA ALEPQGPAVG YNSLPVSDDH HVSGIQARKK QQSVFWIKTE DQPTFNLLRK 
GIMDIEAYLE RIGYKKSRNK LDLETLTDIL QHQIRAVPFE NLNIHCGDAM DLGLEAIFDQ 
VVRRNRGGWC LQVNHLLYWA LTTIGFETTM LGGYVYSTPA KKYSTGMIHL LLQVTIDGRN 
YIVDAGFGRS YQMWQPLELI SGKDQPQVPC VFRLTEENGF WYLDQIRREQ YIPNEEFLHS 
DLLEDSKYRK IYSFTLKPRT IEDFESMNTY LQTSPSSVFT SKSFCSLQTP DGVHCLVGFT 
LTHRRFNYKD NTDLIEFKTL SEEEIEKVLK NIFNISLQRK LVPKHGDRFF TI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.