Details for: NAT1

Gene ID: 9

Symbol: NAT1

Ensembl ID: ENSG00000171428

Description: N-acetyltransferase 1

Associated with

Other Information

Genular Protein ID: 4088468756

Symbol: ARY1_HUMAN

Name: Arylamine N-acetyltransferase 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2340091

Title: Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression.

PubMed ID: 2340091

DOI: 10.1089/dna.1990.9.193

PubMed ID: 1968463

Title: Cloning and expression of cDNAs for polymorphic and monomorphic arylamine N-acetyltransferases from human liver.

PubMed ID: 1968463

DOI: 10.1016/s0021-9258(19)39609-7

PubMed ID: 8442668

Title: Structural heterogeneity of Caucasian N-acetyltransferase at the NAT1 gene locus.

PubMed ID: 8442668

DOI: 10.1006/abbi.1993.1116

PubMed ID: 9168895

Title: Identification of a novel allele at the human NAT1 acetyltransferase locus.

PubMed ID: 9168895

DOI: 10.1006/bbrc.1997.6501

PubMed ID: 9511183

Title: Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by C190T and G560A mutations.

PubMed ID: 9511183

DOI: 10.1097/00008571-199802000-00009

PubMed ID: 10862520

Title: Molecular analysis of the N-acetyltransferase 1 gene (NAT1*) using polymerase chain reaction-restriction fragment-single strand conformation polymorphism assay.

PubMed ID: 10862520

DOI: 10.1097/00008571-200006000-00003

PubMed ID: 16416399

Title: Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes.

PubMed ID: 16416399

DOI: 10.1086/500614

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1676262

Title: Structure and restriction fragment length polymorphism of genes for human liver arylamine N-acetyltransferases.

PubMed ID: 1676262

DOI: 10.1016/0006-291x(91)90676-x

PubMed ID: 9173883

Title: Study of the role of the highly conserved residues Arg9 and Arg64 in the catalytic function of human N-acetyltransferases NAT1 and NAT2 by site-directed mutagenesis.

PubMed ID: 9173883

DOI: 10.1042/bj3230207

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 17656365

Title: Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases.

PubMed ID: 17656365

DOI: 10.1074/jbc.m704138200

PubMed ID: 7585580

Title: Polymorphism in the N-acetyltransferase 1 (NAT1) polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue.

PubMed ID: 7585580

PubMed ID: 9511182

Title: Identification and characterization of variant alleles of human acetyltransferase NAT1 with defective function using p-aminosalicylate as an in-vivo and in-vitro probe.

PubMed ID: 9511182

DOI: 10.1097/00008571-199802000-00008

PubMed ID: 9682272

Title: Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas.

PubMed ID: 9682272

DOI: 10.1097/00008571-199806000-00009

Sequence Information:

  • Length: 290
  • Mass: 33899
  • Checksum: C015F7F3D4830107
  • Sequence:
  • MDIEAYLERI GYKKSRNKLD LETLTDILQH QIRAVPFENL NIHCGDAMDL GLEAIFDQVV 
    RRNRGGWCLQ VNHLLYWALT TIGFETTMLG GYVYSTPAKK YSTGMIHLLL QVTIDGRNYI 
    VDAGFGRSYQ MWQPLELISG KDQPQVPCVF RLTEENGFWY LDQIRREQYI PNEEFLHSDL 
    LEDSKYRKIY SFTLKPRTIE DFESMNTYLQ TSPSSVFTSK SFCSLQTPDG VHCLVGFTLT 
    HRRFNYKDNT DLIEFKTLSE EEIEKVLKNI FNISLQRKLV PKHGDRFFTI

Genular Protein ID: 1510724687

Symbol: F5H5R8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

  • Length: 352
  • Mass: 40846
  • Checksum: 341005CE6234D94F
  • Sequence:
  • MLLLLLHKEA ALEPQGPAVG YNSLPVSDDH HVSGIQARKK QQSVFWIKTE DQPTFNLLRK 
    GIMDIEAYLE RIGYKKSRNK LDLETLTDIL QHQIRAVPFE NLNIHCGDAM DLGLEAIFDQ 
    VVRRNRGGWC LQVNHLLYWA LTTIGFETTM LGGYVYSTPA KKYSTGMIHL LLQVTIDGRN 
    YIVDAGFGRS YQMWQPLELI SGKDQPQVPC VFRLTEENGF WYLDQIRREQ YIPNEEFLHS 
    DLLEDSKYRK IYSFTLKPRT IEDFESMNTY LQTSPSSVFT SKSFCSLQTP DGVHCLVGFT 
    LTHRRFNYKD NTDLIEFKTL SEEEIEKVLK NIFNISLQRK LVPKHGDRFF TI

Genular Protein ID: 219526902

Symbol: Q400J6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 92
  • Mass: 10628
  • Checksum: EE6E18B558D2559C
  • Sequence:
  • MDIEAYLERI GYKKSRNKLD LETLTDILQH QIRAVPFENL NIHCGDAMDL GLEAIFDQVV 
    RRNRGGWCLQ VNHLLYWALT TIGFETTMLG GY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.