F2RL3 | ENSG00000127533 | NCBI 9002

Details for: F2RL3

Gene ID: 9002

Symbol: F2RL3

Ensembl ID: ENSG00000127533

Description: F2R like thrombin or trypsin receptor 3

Associated with

Class a/1 (rhodopsin-like receptors)
(R-HSA-373076)
G alpha (q) signalling events
(R-HSA-416476)
Gpcr downstream signalling
(R-HSA-388396)
Gpcr ligand binding
(R-HSA-500792)
Hemostasis
(R-HSA-109582)
Peptide ligand-binding receptors
(R-HSA-375276)
Platelet activation, signaling and aggregation
(R-HSA-76002)
Signaling by gpcr
(R-HSA-372790)
Thrombin signalling through proteinase activated receptors (pars)
(R-HSA-456926)
Blood coagulation
(GO:0007596)
Extracellular region
(GO:0005576)
G protein-coupled receptor activity
(GO:0004930)
Plasma membrane
(GO:0005886)
Platelet activation
(GO:0030168)
Platelet aggregation
(GO:0070527)
Platelet dense granule organization
(GO:0060155)
Positive regulation of release of sequestered calcium ion into cytosol
(GO:0051281)
Positive regulation of rho protein signal transduction
(GO:0035025)
Protease binding
(GO:0002020)
Response to wounding
(GO:0009611)
Signal transduction
(GO:0007165)
Thrombin-activated receptor activity
(GO:0015057)
Thrombin-activated receptor signaling pathway
(GO:0070493)

Other Information

Proteins

Proteinase-activated receptor 4

Genular Protein ID: 1431212258

Symbol: PAR4_HUMAN

Name: Proteinase-activated receptor 4

UniProtKB Accession Codes:

Q96RI0 O76067 Q6DK42

Database IDs:

Citations:

PubMed ID: 9722561

Title: Gene and locus structure and chromosomal localization of the protease-activated receptor gene family.

PubMed ID: 9722561

DOI: 10.1074/jbc.273.36.23290

PubMed ID: 9716134

Title: A dual thrombin receptor system for platelet activation.

PubMed ID: 9716134

DOI: 10.1038/29325

PubMed ID: 9618465

Title: Cloning and characterization of human protease-activated receptor 4.

PubMed ID: 9618465

DOI: 10.1073/pnas.95.12.6642

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10079109

Title: Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin.

PubMed ID: 10079109

DOI: 10.1172/jci6042

PubMed ID: 18434511

Title: Cowhage-evoked itch is mediated by a novel cysteine protease: a ligand of protease-activated receptors.

PubMed ID: 18434511

DOI: 10.1523/jneurosci.0716-08.2008

Sequence Information:

Length: 385
Mass: 41133
Checksum: FACE32F10D5C561E
Sequence:

MWGRLLLWPL VLGFSLSGGT QTPSVYDESG STGGGDDSTP SILPAPRGYP GQVCANDSDT 
LELPDSSRAL LLGWVPTRLV PALYGLVLVV GLPANGLALW VLATQAPRLP STMLLMNLAA 
ADLLLALALP PRIAYHLRGQ RWPFGEAACR LATAALYGHM YGSVLLLAAV SLDRYLALVH 
PLRARALRGR RLALGLCMAA WLMAAALALP LTLQRQTFRL ARSDRVLCHD ALPLDAQASH 
WQPAFTCLAL LGCFLPLLAM LLCYGATLHT LAASGRRYGH ALRLTAVVLA SAVAFFVPSN 
LLLLLHYSDP SPSAWGNLYG AYVPSLALST LNSCVDPFIY YYVSAEFRDK VRAGLFQRSP 
GDTVASKASA EGGSRGMGTH SSLLQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: F2RL3

Associated with

Other Information

Gene and locus structure and chromosomal localization of the protease-activated receptor gene family. PubMed ID: 9722561

A dual thrombin receptor system for platelet activation. PubMed ID: 9716134

Cloning and characterization of human protease-activated receptor 4. PubMed ID: 9618465

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. PubMed ID: 10079109