Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cardiac neuron (CL0010022)
Fold Change: 3
Marker Score: 3,738 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 2.93
Marker Score: 3,540 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.78
Marker Score: 11,644 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.77
Marker Score: 21,252 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.72
Marker Score: 40,715 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.7
Marker Score: 3,108 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.66
Marker Score: 100,968 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 2.65
Marker Score: 3,568 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 2.56
Marker Score: 7,191 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.54
Marker Score: 5,578 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.46
Marker Score: 48,881 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.43
Marker Score: 51,863 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 2.42
Marker Score: 3,345 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 2.42
Marker Score: 2,060 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.34
Marker Score: 9,709 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.29
Marker Score: 4,397 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 2.25
Marker Score: 1,091 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 2.24
Marker Score: 5,370 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.24
Marker Score: 1,311 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.24
Marker Score: 654 - Cell Name: fat cell (CL0000136)
Fold Change: 2.22
Marker Score: 1,243 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.22
Marker Score: 8,567 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 2.13
Marker Score: 1,610 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.07
Marker Score: 1,235 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 2.06
Marker Score: 1,026 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.03
Marker Score: 3,411 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.02
Marker Score: 18,987 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 2.01
Marker Score: 7,138 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 2
Marker Score: 2,152 - Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 1.99
Marker Score: 1,747 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 1.98
Marker Score: 991 - Cell Name: mature T cell (CL0002419)
Fold Change: 1.98
Marker Score: 19,636 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.95
Marker Score: 71,758 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.94
Marker Score: 1,080 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.94
Marker Score: 119,375 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.93
Marker Score: 43,093 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 1.89
Marker Score: 585 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.89
Marker Score: 5,380 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 1.85
Marker Score: 1,085 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.85
Marker Score: 584 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.84
Marker Score: 17,450 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 1.82
Marker Score: 551 - Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
Fold Change: 1.79
Marker Score: 1,104 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 1.79
Marker Score: 4,374 - Cell Name: renal principal cell (CL0005009)
Fold Change: 1.78
Marker Score: 1,371 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.77
Marker Score: 1,537 - Cell Name: Schwann cell (CL0002573)
Fold Change: 1.77
Marker Score: 613 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.76
Marker Score: 598 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.71
Marker Score: 1,635 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.71
Marker Score: 14,709 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.71
Marker Score: 693 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.71
Marker Score: 2,113 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 1.69
Marker Score: 704 - Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: 1.69
Marker Score: 2,484 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 1.67
Marker Score: 723 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 1.65
Marker Score: 868 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 1.63
Marker Score: 7,004 - Cell Name: podocyte (CL0000653)
Fold Change: 1.59
Marker Score: 590 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 1.59
Marker Score: 1,335 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.57
Marker Score: 571 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.55
Marker Score: 370 - Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
Fold Change: 1.53
Marker Score: 697 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.53
Marker Score: 1,406 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.52
Marker Score: 51,855 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 1.52
Marker Score: 482 - Cell Name: Unknown (CL0000548)
Fold Change: 1.52
Marker Score: 1,109 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 1.52
Marker Score: 1,655 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.52
Marker Score: 2,147 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 1.51
Marker Score: 1,181 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.48
Marker Score: 1,571 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.48
Marker Score: 2,280 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 1.48
Marker Score: 323 - Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 1.47
Marker Score: 1,303 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 1.46
Marker Score: 2,602 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.45
Marker Score: 548 - Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
Fold Change: 1.45
Marker Score: 1,049 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.45
Marker Score: 417 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 1.45
Marker Score: 332 - Cell Name: cardiac mesenchymal cell (CL0000569)
Fold Change: 1.44
Marker Score: 356 - Cell Name: radial glial cell (CL0000681)
Fold Change: 1.42
Marker Score: 525 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 1.42
Marker Score: 377 - Cell Name: dendritic cell, human (CL0001056)
Fold Change: 1.42
Marker Score: 1,445 - Cell Name: gamma-delta T cell (CL0000798)
Fold Change: 1.41
Marker Score: 949 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.41
Marker Score: 822 - Cell Name: blood cell (CL0000081)
Fold Change: 1.41
Marker Score: 16,392 - Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
Fold Change: 1.4
Marker Score: 1,029 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 1.4
Marker Score: 313 - Cell Name: granulocyte (CL0000094)
Fold Change: 1.4
Marker Score: 627 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 1.4
Marker Score: 370 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 1.39
Marker Score: 1,303 - Cell Name: ependymal cell (CL0000065)
Fold Change: 1.39
Marker Score: 484 - Cell Name: interneuron (CL0000099)
Fold Change: 1.38
Marker Score: 632 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 1.38
Marker Score: 796 - Cell Name: basophil (CL0000767)
Fold Change: 1.37
Marker Score: 650 - Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
Fold Change: 1.36
Marker Score: 299 - Cell Name: IgA plasmablast (CL0000984)
Fold Change: 1.35
Marker Score: 356 - Cell Name: epidermal cell (CL0000362)
Fold Change: 1.35
Marker Score: 380 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: 1.35
Marker Score: 1,106 - Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 1.35
Marker Score: 264 - Cell Name: memory T cell (CL0000813)
Fold Change: 1.34
Marker Score: 578
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2847686331
Symbol: CCNH_HUMAN
Name: Cyclin-H
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8078587
Title: A cyclin associated with the CDK-activating kinase MO15.
PubMed ID: 8078587
DOI: 10.1038/371254a0
PubMed ID: 8069918
Title: A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase.
PubMed ID: 8069918
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7533895
Title: Cdk-activating kinase complex is a component of human transcription factor TFIIH.
PubMed ID: 7533895
DOI: 10.1038/374283a0
PubMed ID: 9852112
Title: Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.
PubMed ID: 9852112
PubMed ID: 10024882
Title: Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7.
PubMed ID: 10024882
PubMed ID: 10993082
Title: TFIIH is negatively regulated by cdk8-containing mediator complexes.
PubMed ID: 10993082
DOI: 10.1038/35024111
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 8836101
Title: Three-dimensional structure of human cyclin H, a positive regulator of the CDK-activating kinase.
PubMed ID: 8836101
DOI: 10.1038/nsb1096-849
PubMed ID: 9118957
Title: The structure of cyclin H: common mode of kinase activation and specific features.
PubMed ID: 9118957
Sequence Information:
- Length: 323
- Mass: 37643
- Checksum: BB48D55DA397A0E4
- Sequence:
MYHNSSQKRH WTFSSEEQLA RLRADANRKF RCKAVANGKV LPNDPVFLEP HEEMTLCKYY EKRLLEFCSV FKPAMPRSVV GTACMYFKRF YLNNSVMEYH PRIIMLTCAF LACKVDEFNV SSPQFVGNLR ESPLGQEKAL EQILEYELLL IQQLNFHLIV HNPYRPFEGF LIDLKTRYPI LENPEILRKT ADDFLNRIAL TDAYLLYTPS QIALTAILSS ASRAGITMES YLSESLMLKE NRTCLSQLLD IMKSMRNLVK KYEPPRSEEV AVLKQKLERC HSAELALNVI TKKRKGYEDD DYVSKKSKHE EEEWTDDDLV ESL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.