Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.45
Marker Score: 1545 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.13
Marker Score: 1188 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 1.08
Marker Score: 1066 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.04
Marker Score: 16350 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71654 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.99
Marker Score: 429 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47876 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30384 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.95
Marker Score: 8192 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.95
Marker Score: 58382.5 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.95
Marker Score: 8987 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 0.94
Marker Score: 472 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2387 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.94
Marker Score: 31941 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.94
Marker Score: 1444 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 478 - Cell Name: neuron (CL0000540)
Fold Change: 0.92
Marker Score: 3764 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 0.92
Marker Score: 48860 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 436 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.92
Marker Score: 9522 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.91
Marker Score: 616 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.91
Marker Score: 9180 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2689 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 0.89
Marker Score: 834 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.89
Marker Score: 439 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.88
Marker Score: 2074 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5292 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 0.86
Marker Score: 852 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 0.86
Marker Score: 654 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.86
Marker Score: 299 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 308 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 0.85
Marker Score: 2679 - Cell Name: Unknown (CL0000548)
Fold Change: 0.85
Marker Score: 618 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.84
Marker Score: 3518 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.84
Marker Score: 1010 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 0.83
Marker Score: 2320.5 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.82
Marker Score: 399 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.82
Marker Score: 4685 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.82
Marker Score: 468 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 0.82
Marker Score: 254 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: 0.81
Marker Score: 288 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.81
Marker Score: 324 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.81
Marker Score: 329 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 0.8
Marker Score: 483 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.8
Marker Score: 1759.5 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 0.8
Marker Score: 2206.5 - Cell Name: Unknown (CL0002371)
Fold Change: 0.8
Marker Score: 848 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.8
Marker Score: 732 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 0.8
Marker Score: 1943 - Cell Name: neural cell (CL0002319)
Fold Change: 0.79
Marker Score: 381 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.79
Marker Score: 492.5 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 0.79
Marker Score: 272 - Cell Name: basal cell (CL0000646)
Fold Change: 0.79
Marker Score: 1016 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.79
Marker Score: 189 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.79
Marker Score: 905 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.78
Marker Score: 186 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.78
Marker Score: 7315.5 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1259 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.77
Marker Score: 834 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.77
Marker Score: 223 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.77
Marker Score: 590 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.77
Marker Score: 966.5 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.77
Marker Score: 851 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 0.77
Marker Score: 233.5 - Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
Fold Change: 0.77
Marker Score: 830 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.77
Marker Score: 224.5 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.77
Marker Score: 522 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.77
Marker Score: 460 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.76
Marker Score: 1869 - Cell Name: cardiac mesenchymal cell (CL0000569)
Fold Change: 0.76
Marker Score: 187 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.76
Marker Score: 307 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 0.76
Marker Score: 824 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.75
Marker Score: 2908.5 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.75
Marker Score: 1108 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.75
Marker Score: 27705.5 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.75
Marker Score: 511 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: 0.75
Marker Score: 612 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 0.74
Marker Score: 4389.5 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.74
Marker Score: 7440.5 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.74
Marker Score: 255 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 0.73
Marker Score: 615 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.73
Marker Score: 15510 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 0.72
Marker Score: 999.5 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.72
Marker Score: 27466 - Cell Name: podocyte (CL0000653)
Fold Change: 0.72
Marker Score: 266 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 372 - Cell Name: blood vessel smooth muscle cell (CL0019018)
Fold Change: 0.72
Marker Score: 189 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.72
Marker Score: 455 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 0.72
Marker Score: 164 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.71
Marker Score: 470 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.71
Marker Score: 2975 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.71
Marker Score: 163 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.71
Marker Score: 12558 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 0.71
Marker Score: 1027 - Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
Fold Change: 0.71
Marker Score: 434 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 0.71
Marker Score: 708 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.7
Marker Score: 760 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.7
Marker Score: 265 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 0.7
Marker Score: 551 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.7
Marker Score: 13963
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Other Information
Genular Protein ID: 1113320453
Symbol: CCNT1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9491887
Title: A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA.
PubMed ID: 9491887
PubMed ID: 9499409
Title: Identification of multiple cyclin subunits of human P-TEFb.
PubMed ID: 9499409
DOI: 10.1101/gad.12.5.755
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 10393184
Title: A novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription.
PubMed ID: 10393184
PubMed ID: 10329125
Title: Cyclin T1 domains involved in complex formation with Tat and TAR RNA are critical for tat-activation.
PubMed ID: 10329125
PubMed ID: 10329126
Title: Role of the human and murine cyclin T proteins in regulating HIV-1 Tat-activation.
PubMed ID: 10329126
PubMed ID: 9832504
Title: The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein.
PubMed ID: 9832504
PubMed ID: 10364329
Title: Analysis of the effect of natural sequence variation in Tat and in cyclin T on the formation and RNA binding properties of Tat-cyclin T complexes.
PubMed ID: 10364329
PubMed ID: 10913173
Title: Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter.
PubMed ID: 10913173
PubMed ID: 12065898
Title: MCEF, the newest member of the AF4 family of transcription factors involved in leukemia, is a positive transcription elongation factor-b-associated protein.
PubMed ID: 12065898
DOI: 10.1007/bf02256070
PubMed ID: 12944466
Title: The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription.
PubMed ID: 12944466
PubMed ID: 14972556
Title: Evidence for conformational flexibility in the Tat-TAR recognition motif of cyclin T1.
PubMed ID: 14972556
PubMed ID: 16109376
Title: The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.
PubMed ID: 16109376
PubMed ID: 16109377
Title: Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4.
PubMed ID: 16109377
PubMed ID: 17643375
Title: Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
PubMed ID: 17643375
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24360279
Title: Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release.
PubMed ID: 24360279
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 27292648
Title: T-bet activates Th1 genes through mediator and the super elongation complex.
PubMed ID: 27292648
PubMed ID: 27189267
Title: Heat shock factor 1 mediates latent HIV reactivation.
PubMed ID: 27189267
DOI: 10.1038/srep26294
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 30134174
Title: Positive Regulation of Transcription by Human ZMYND8 through Its Association with P-TEFb Complex.
PubMed ID: 30134174
PubMed ID: 29849146
Title: Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II.
PubMed ID: 29849146
PubMed ID: 34696162
Title: HSV-1 ICP22 Is a Selective Viral Repressor of Cellular RNA Polymerase II-Mediated Transcription Elongation.
PubMed ID: 34696162
PubMed ID: 35393539
Title: Poly(ADP-ribosylation) of P-TEFb by PARP1 disrupts phase separation to inhibit global transcription after DNA damage.
PubMed ID: 35393539
PubMed ID: 23033978
Title: Diagnostic exome sequencing in persons with severe intellectual disability.
PubMed ID: 23033978
Sequence Information:
- Length: 726
- Mass: 80685
- Checksum: 4637EFB2DDEDFE13
- Sequence:
MEGERKNNNK RWYFTREQLE NSPSRRFGVD PDKELSYRQQ AANLLQDMGQ RLNVSQLTIN TAIVYMHRFY MIQSFTQFPG NSVAPAALFL AAKVEEQPKK LEHVIKVAHT CLHPQESLPD TRSEAYLQQV QDLVILESII LQTLGFELTI DHPHTHVVKC TQLVRASKDL AQTSYFMATN SLHLTTFSLQ YTPPVVACVC IHLACKWSNW EIPVSTDGKH WWEYVDATVT LELLDELTHE FLQILEKTPN RLKRIWNWRA CEAAKKTKAD DRGTDEKTSE QTILNMISQS SSDTTIAGLM SMSTSTTSAV PSLPVSEESS SNLTSVEMLP GKRWLSSQPS FKLEPTQGHR TSENLALTGV DHSLPQDGSN AFISQKQNSK SVPSAKVSLK EYRAKHAEEL AAQKRQLENM EANVKSQYAY AAQNLLSHHD SHSSVILKMP IEGSENPERP FLEKADKTAL KMRIPVAGGD KAASSKPEEI KMRIKVHAAA DKHNSVEDSV TKSREHKEKH KTHPSNHHHH HNHHSHKHSH SQLPVGTGNK RPGDPKHSSQ TSNLAHKTYS LSSSFSSSSS TRKRGPSEET GGAVFDHPAK IAKSTKSSSL NFSFPSLPTM GQMPGHSSDT SGLSFSQPSC KTRVPHSKLD KGPTGANGHN TTQTIDYQDT VNMLHSLLSA QGVQPTQPTA FEFVRPYSDY LNPRSGGISS RSGNTDKPRP PPLPSEPPPP LPPLPK
Genular Protein ID: 1439126333
Symbol: A8K4M5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 726
- Mass: 80585
- Checksum: 062A44C4849C2D4A
- Sequence:
MEGERKNNNK RWYFTREQLE NSPSRRFGVD PDKELSYRQQ AANLLQDMGQ RLNVSQLTIN TAIVYMHRFY MIQSFTQFPG NSVAPAALFL AAKVEEQPKK LEHVIKVAHT CLHPQESLPD TRSEAYLQQV QDLVILESII LQTLGFELTI DHPHTHVVKC TQLVRASKDL AQTSYFMATN SLHLTTFSLQ YTPPVVACVC IHLACKWSNW EIPVSTDGKH WWEYVDATVT LELLDELTHE FLQILEKTPN GLKRIWNWRA CEAAKKTKAD DRGTDEKTSE QTILNMISQS SSDTTIAGLM SMSTSTTSAV PSLPVSEESS SNLTSVEMLP GKRWLSSQPS FKLEPTQGHR TSENLALTGV DHSLPQDGSN AFISQKQNSK SVPSAKVSLK EYRAKHAEEL AAQKRQLENM EANVKSQYAY AAQNLLSHHD SHSSVILKMP IEGSENPERP FLEKADKTAL KMRIPVAGGD KAASSKPEEI KMRIKVHAAA DKHNSVEDSV TKSREHKEKH KTHPSNHHHH HNHHSHKHSH SQLPVGTGNK RPGDPKHSSQ TSNLAHKTYS LSSSFSSSSS TRKRGPSEET GGAVFDHPAK IAKSTKSSSL NFSFPSLPTM GQMPGHSSDT SGLSFSQPSC KTRVPHSKLD KGPTGANGHN TTQTIDYQDT VNMLHSLLSA QGVQPTQPTA FEFVRPYSDY LNPRSGGISS RSGNTDKPRP PPLPSEPPPP LPPLPK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.