CCT6A | ENSG00000146731 | NCBI 908

Details for: CCT6A

Gene ID: 908

Symbol: CCT6A

Ensembl ID: ENSG00000146731

Description: chaperonin containing TCP1 subunit 6A

Associated with

Association of tric/cct with target proteins during biosynthesis
(R-HSA-390471)
Chaperonin-mediated protein folding
(R-HSA-390466)
Cooperation of pdcl (phlp1) and tric/cct in g-protein beta folding
(R-HSA-6814122)
Cooperation of prefoldin and tric/cct in actin and tubulin folding
(R-HSA-389958)
Folding of actin by cct/tric
(R-HSA-390450)
Formation of tubulin folding intermediates by cct/tric
(R-HSA-389960)
Metabolism of proteins
(R-HSA-392499)
Prefoldin mediated transfer of substrate to cct/tric
(R-HSA-389957)
Rhobtb2 gtpase cycle
(R-HSA-9013418)
Rhobtb gtpase cycle
(R-HSA-9706574)
Rho gtpase cycle
(R-HSA-9012999)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Atp-dependent protein folding chaperone
(GO:0140662)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Chaperone-mediated protein folding
(GO:0061077)
Chaperonin-containing t-complex
(GO:0005832)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Extracellular exosome
(GO:0070062)
Microtubule
(GO:0005874)
Positive regulation of establishment of protein localization to telomere
(GO:1904851)
Positive regulation of protein localization to cajal body
(GO:1904871)
Positive regulation of telomerase rna localization to cajal body
(GO:1904874)
Positive regulation of telomere maintenance via telomerase
(GO:0032212)
Protein binding
(GO:0005515)
Protein folding
(GO:0006457)
Protein folding chaperone
(GO:0044183)
Protein stabilization
(GO:0050821)
Rna binding
(GO:0003723)
Unfolded protein binding
(GO:0051082)
Wd40-repeat domain binding
(GO:0071987)

Other Information

Proteins

T-complex protein 1 subunit zeta

Genular Protein ID: 225150841

Symbol: TCPZ_HUMAN

Name: T-complex protein 1 subunit zeta

UniProtKB Accession Codes:

P40227 A6NCD2 Q3KP28 Q75LP4 Q96S46

Database IDs:

Citations:

PubMed ID: 8034610

Title: Tcp20, a subunit of the eukaryotic TRiC chaperonin from humans and yeast.

PubMed ID: 8034610

DOI: 10.1016/s0021-9258(17)32354-2

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1352881

Title: Isolation of a gene encoding a chaperonin-like protein by complementation of yeast amino acid transport mutants with human cDNA.

PubMed ID: 1352881

DOI: 10.1073/pnas.89.13.6060

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 14532270

Title: A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death.

PubMed ID: 14532270

DOI: 10.1074/jbc.m309655200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25467444

Title: Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1.

PubMed ID: 25467444

DOI: 10.1016/j.cell.2014.10.059

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

Length: 531
Mass: 58024
Checksum: 43ABCF548CC82B81
Sequence:

MAAVKTLNPK AEVARAQAAL AVNISAARGL QDVLRTNLGP KGTMKMLVSG AGDIKLTKDG 
NVLLHEMQIQ HPTASLIAKV ATAQDDITGD GTTSNVLIIG ELLKQADLYI SEGLHPRIIT 
EGFEAAKEKA LQFLEEVKVS REMDRETLID VARTSLRTKV HAELADVLTE AVVDSILAIK 
KQDEPIDLFM IEIMEMKHKS ETDTSLIRGL VLDHGARHPD MKKRVEDAYI LTCNVSLEYE 
KTEVNSGFFY KSAEEREKLV KAERKFIEDR VKKIIELKRK VCGDSDKGFV VINQKGIDPF 
SLDALSKEGI VALRRAKRRN MERLTLACGG VALNSFDDLS PDCLGHAGLV YEYTLGEEKF 
TFIEKCNNPR SVTLLIKGPN KHTLTQIKDA VRDGLRAVKN AIDDGCVVPG AGAVEVAMAE 
ALIKHKPSVK GRAQLGVQAF ADALLIIPKV LAQNSGFDLQ ETLVKIQAEH SESGQLVGVD 
LNTGEPMVAA EVGVWDNYCV KKQLLHSCTV IATNILLVDE IMRAGMSSLK G

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CCT6A

Associated with

Other Information

Tcp20, a subunit of the eukaryotic TRiC chaperonin from humans and yeast. PubMed ID: 8034610

The DNA sequence of human chromosome 7. PubMed ID: 12853948

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Isolation of a gene encoding a chaperonin-like protein by complementation of yeast amino acid transport mutants with human cDNA. PubMed ID: 1352881

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. PubMed ID: 12665801

A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. PubMed ID: 14532270

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1. PubMed ID: 25467444

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733