Details for: EIF1AY
Gene ID: 9086
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: EIF1AY
Ensembl ID: ENSG00000198692
Description: eukaryotic translation initiation factor 1A Y-linked
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 14.83rCSI 17.15%PRS 60.7
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CSI 14.18rCSI 23.22%PRS 58.78
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CSI 8.53rCSI 8.06%PRS 68.95
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CSI 8.08rCSI 7.3%PRS 67.08
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CSI 7.97rCSI 8.35%PRS 73.31
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CSI 7.79rCSI 6.06%PRS 85.98
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CSI 7.72rCSI 9.56%PRS 66.7
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CSI 7.69rCSI 41.49%PRS 79.36
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CSI 7.67rCSI 17.41%PRS 71.79
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CSI 6.7rCSI 19.4%PRS 70.41
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CSI 6.11rCSI 4.56%PRS 84.66
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CSI 6.1rCSI 7.65%PRS 79.77
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CSI 5.93rCSI 4.4%PRS 82.33
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CSI 5.41rCSI 5.32%PRS 72.37
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CSI 4.9rCSI 3.41%PRS 84.44
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CSI 4.61rCSI 3.2%PRS 81.18
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CSI 4.57rCSI 7.13%PRS 89.71
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CSI 4.38rCSI 6.25%PRS 71.74
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CSI 4.32rCSI 19%PRS 59.08
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CSI 4.27rCSI 12.26%PRS 88.13
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CSI 4.13rCSI 3.48%PRS 84.87
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CSI 4.11rCSI 2.95%PRS 83.19
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CSI 4.09rCSI 3.21%PRS 76.31
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CSI 4.02rCSI 4.85%PRS 78.75
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CSI 3.84rCSI 5.54%PRS 77.75
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CSI 3.72rCSI 2.98%PRS 86.92
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CSI 3.67rCSI 4.2%PRS 84.81
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CSI 3.67rCSI 6.04%PRS 75.11
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CSI 3.5rCSI 6.67%PRS 82.54
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CSI 3.26rCSI 2.7%PRS 69.68
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CSI 3.22rCSI 4.47%PRS 68.32
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CSI 3.11rCSI 6.97%PRS 51.65
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CSI 3rCSI 2.75%PRS 78.81
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CSI 2.98rCSI 2.64%PRS 67.55
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CSI 2.96rCSI 2.19%PRS 62.54
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CSI 2.95rCSI 1.96%PRS 72.62
-
CSI 2.94rCSI 5.18%PRS 77.16
-
CSI 2.88rCSI 3.77%PRS 89.21
-
CSI 2.88rCSI 2.96%PRS 84.42
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CSI 2.77rCSI 1.94%PRS 72.66
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CSI 2.59rCSI 4.65%PRS 62.89
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CSI 2.57rCSI 2.68%PRS 67.42
-
CSI 2.56rCSI 4.15%PRS 65.48
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CSI 2.49rCSI 8.14%PRS 90.13
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CSI 2.47rCSI 3.28%PRS 76.1
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CSI 2.46rCSI 3.22%PRS 82.43
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CSI 2.45rCSI 2.15%PRS 75.12
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CSI 2.36rCSI 6.98%PRS 71.89
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CSI 2.35rCSI 1.86%PRS 56.99
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CSI 2.32rCSI 1.84%PRS 88.74
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CSI 2.32rCSI 1.92%PRS 72.2
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CSI 2.31rCSI 4.73%PRS 84.57
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CSI 2.27rCSI 2.26%PRS 63.25
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CSI 2.25rCSI 2.59%PRS 62.34
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CSI 2.19rCSI 2.02%PRS 86.93
-
CSI 2.09rCSI 4.63%PRS 68.33
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CSI 2.07rCSI 2.17%PRS 66.67
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CSI 2.05rCSI 2.2%PRS 70.1
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CSI 2.05rCSI 2.09%PRS 81.17
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CSI 2.04rCSI 2.09%PRS 81.35
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CSI 1.98rCSI 2.54%PRS 66.42
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CSI 1.96rCSI 1.81%PRS 71.48
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CSI 1.88rCSI 2.56%PRS 61.24
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CSI 1.88rCSI 1.46%PRS 72.95
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CSI 1.86rCSI 1.62%PRS 80.19
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CSI 1.84rCSI 2.16%PRS 71.86
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CSI 1.79rCSI 11.2%PRS 61.11
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CSI 1.74rCSI 2.66%PRS 78.86
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CSI 1.73rCSI 2.49%PRS 78.82
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CSI 1.73rCSI 5%PRS 79.25
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CSI 1.71rCSI 1.39%PRS 71.58
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CSI 1.71rCSI 2.08%PRS 77.05
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CSI 1.71rCSI 4.88%PRS 78.95
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CSI 1.69rCSI 2.59%PRS 79
-
CSI 1.68rCSI 2.56%PRS 66.06
-
CSI 1.67rCSI 4.99%PRS 83.36
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CSI 1.66rCSI 2.54%PRS 74.17
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CSI 1.65rCSI 1.97%PRS 84.11
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CSI 1.63rCSI 2.59%PRS 62.42
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CSI 1.57rCSI 3.51%PRS 77.73
-
CSI 1.57rCSI 8.08%PRS 88.5
-
CSI 1.55rCSI 1.35%PRS 74.46
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CSI 1.55rCSI 2.36%PRS 81.44
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CSI 1.53rCSI 2.88%PRS 81.46
-
CSI 1.53rCSI 2.09%PRS 70.75
-
CSI 1.51rCSI 2.93%PRS 73.06
-
CSI 1.4rCSI 3.72%PRS 78.9
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CSI 1.34rCSI 1.82%PRS 80.13
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CSI 1.28rCSI 2.31%PRS 88.45
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CSI 1.27rCSI 5.63%PRS 69.99
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CSI 1.26rCSI 2.77%PRS 76.58
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CSI 1.16rCSI 3.73%PRS 67.36
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CSI 1.14rCSI 2.27%PRS 84.75
-
CSI 1.13rCSI 4.09%PRS 87.11
-
CSI 1.13rCSI 1.4%PRS 71.53
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CSI 1.12rCSI 1.73%PRS 68.47
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CSI 1.12rCSI 4.44%PRS 80.06
-
CSI 1.09rCSI 2.41%PRS 80.59
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CSI 1.07rCSI 1.58%PRS 83.33
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CSI 1.06rCSI 2.85%PRS 76
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CSI 0.1rCSI 1.9%PRS 91.0%
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CSI 0.3rCSI 4.9%PRS 92.2%
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CSI 0.4rCSI 2.8%PRS 91.3%
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CSI 0.5rCSI 2.7%PRS 77.5%
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CSI 0.5rCSI 3.0%PRS 76.8%
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CSI 0.6rCSI 2.4%PRS 79.5%
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CSI 0.6rCSI 2.5%PRS 93.6%
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CSI 0.6rCSI 2.7%PRS 81.8%
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CSI 0.7rCSI 3.5%PRS 79.6%
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CSI 0.7rCSI 4.2%PRS 85.4%
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CSI 0.7rCSI 1.7%PRS 85.7%
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CSI 0.7rCSI 3.3%PRS 92.0%
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CSI 0.8rCSI 1.9%PRS 65.1%
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CSI 0.8rCSI 2.7%PRS 73.4%
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CSI 0.9rCSI 2.5%PRS 79.3%
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CSI 0.9rCSI 5.0%PRS 92.9%
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CSI 0.9rCSI 7.1%PRS 83.3%
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CSI 1.0rCSI 1.4%PRS 74.8%
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CSI 1.0rCSI 1.4%PRS 59.2%
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CSI 1.1rCSI 2.9%PRS 76.0%
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CSI 1.1rCSI 1.6%PRS 83.3%
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CSI 1.1rCSI 2.4%PRS 80.6%
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CSI 1.1rCSI 4.4%PRS 80.1%
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CSI 1.1rCSI 1.7%PRS 68.5%
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CSI 1.1rCSI 1.4%PRS 71.5%
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CSI 1.1rCSI 4.1%PRS 87.1%
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CSI 1.1rCSI 2.3%PRS 84.8%
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CSI 1.2rCSI 3.7%PRS 67.4%
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CSI 1.3rCSI 2.8%PRS 76.6%
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CSI 1.3rCSI 5.6%PRS 70.0%
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CSI 1.3rCSI 2.3%PRS 88.5%
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CSI 1.3rCSI 1.8%PRS 80.1%
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CSI 1.4rCSI 3.7%PRS 78.9%
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CSI 1.5rCSI 2.9%PRS 73.1%
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CSI 1.5rCSI 2.1%PRS 70.8%
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CSI 1.5rCSI 2.9%PRS 81.5%
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CSI 1.6rCSI 2.4%PRS 81.4%
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CSI 1.6rCSI 1.4%PRS 74.5%
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CSI 1.6rCSI 8.1%PRS 88.5%
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CSI 1.6rCSI 3.5%PRS 77.7%
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CSI 1.6rCSI 2.6%PRS 62.4%
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CSI 1.7rCSI 2.0%PRS 84.1%
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CSI 1.7rCSI 2.5%PRS 74.2%
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CSI 1.7rCSI 5.0%PRS 83.4%
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CSI 1.7rCSI 2.6%PRS 66.1%
-
CSI 1.7rCSI 2.6%PRS 79.0%
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CSI 1.7rCSI 4.9%PRS 79.0%
-
CSI 1.7rCSI 2.1%PRS 77.1%
-
CSI 1.7rCSI 1.4%PRS 71.6%
-
CSI 1.7rCSI 5.0%PRS 79.3%
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CSI 1.7rCSI 2.5%PRS 78.8%
-
CSI 1.7rCSI 2.7%PRS 78.9%
-
CSI 1.8rCSI 11.2%PRS 61.1%
-
CSI 1.8rCSI 2.2%PRS 71.9%
-
CSI 1.9rCSI 1.6%PRS 80.2%
-
CSI 1.9rCSI 1.5%PRS 73.0%
-
CSI 1.9rCSI 2.6%PRS 61.2%
-
CSI 2.0rCSI 1.8%PRS 71.5%
-
CSI 2.0rCSI 2.5%PRS 66.4%
-
CSI 2.0rCSI 2.1%PRS 81.4%
-
CSI 2.1rCSI 2.1%PRS 81.2%
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CSI 2.1rCSI 2.2%PRS 70.1%
-
CSI 2.1rCSI 2.2%PRS 66.7%
-
CSI 2.1rCSI 4.6%PRS 68.3%
-
CSI 2.2rCSI 2.0%PRS 86.9%
-
CSI 2.3rCSI 2.6%PRS 62.3%
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CSI 2.3rCSI 2.3%PRS 63.3%
-
CSI 2.3rCSI 4.7%PRS 84.6%
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CSI 2.3rCSI 1.9%PRS 72.2%
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CSI 2.3rCSI 1.8%PRS 88.7%
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CSI 2.4rCSI 1.9%PRS 57.0%
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CSI 2.4rCSI 7.0%PRS 71.9%
-
CSI 2.5rCSI 2.2%PRS 75.1%
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CSI 2.5rCSI 3.2%PRS 82.4%
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CSI 2.5rCSI 3.3%PRS 76.1%
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CSI 2.5rCSI 8.1%PRS 90.1%
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CSI 2.6rCSI 4.2%PRS 65.5%
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CSI 2.6rCSI 2.7%PRS 67.4%
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CSI 2.6rCSI 4.7%PRS 62.9%
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CSI 2.8rCSI 1.9%PRS 72.7%
-
CSI 2.9rCSI 3.0%PRS 84.4%
-
CSI 2.9rCSI 3.8%PRS 89.2%
-
CSI 2.9rCSI 5.2%PRS 77.2%
-
CSI 3.0rCSI 2.0%PRS 72.6%
-
CSI 3.0rCSI 2.2%PRS 62.5%
-
CSI 3.0rCSI 2.6%PRS 67.6%
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CSI 3.0rCSI 2.8%PRS 78.8%
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CSI 3.1rCSI 7.0%PRS 51.7%
-
CSI 3.2rCSI 4.5%PRS 68.3%
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CSI 3.3rCSI 2.7%PRS 69.7%
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CSI 3.5rCSI 6.7%PRS 82.5%
-
CSI 3.7rCSI 6.0%PRS 75.1%
-
CSI 3.7rCSI 4.2%PRS 84.8%
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CSI 3.7rCSI 3.0%PRS 86.9%
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CSI 3.8rCSI 5.5%PRS 77.8%
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CSI 4.0rCSI 4.9%PRS 78.8%
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CSI 4.1rCSI 3.2%PRS 76.3%
-
CSI 4.1rCSI 3.0%PRS 83.2%
-
CSI 4.1rCSI 3.5%PRS 84.9%
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CSI 4.3rCSI 12.3%PRS 88.1%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 2570481336
Symbol: IF1AY_HUMAN
Name: Eukaryotic translation initiation factor 1A, Y-chromosomal
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9381176
Title: Functional coherence of the human Y chromosome.
PubMed ID: 9381176
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 144
- Mass: 16442
- Checksum: 1DE91334F191BEC5
- Sequence:
MPKNKGKGGK NRRRGKNENE SEKRELVFKE DGQEYAQVIK MLGNGRLEAL CFDGVKRLCH IRGKLRKKVW INTSDIILVG LRDYQDNKAD VILKYNADEA RSLKAYGELP EHAKINETDT FGPGDDDEIQ FDDIGDDDED IDDI
Genular Protein ID: 1190991126
Symbol: A6NJH9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 12815422
Title: The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes.
PubMed ID: 12815422
DOI: 10.1038/nature01722
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 127
- Mass: 14455
- Checksum: 4C2F3F03DCC651D3
- Sequence:
MPKNKGKGGK NRRRGKNENE SEKRELVFKE DGQEYAQVIK MLGNGRLEAL CFDGVKRLCH IRGKLRKKDN KADVILKYNA DEARSLKAYG ELPEHAKINE TDTFGPGDDD EIQFDDIGDD DEDIDDI