Details for: USP6

Gene ID: 9098

Symbol: USP6

Ensembl ID: ENSG00000129204

Description: ubiquitin specific peptidase 6

Associated with

Other Information

Genular Protein ID: 1460081987

Symbol: UBP6_HUMAN

Name: Ubiquitin carboxyl-terminal hydrolase 6

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1565468

Title: A novel transcriptional unit of the tre oncogene widely expressed in human cancer cells.

PubMed ID: 1565468

PubMed ID: 12604796

Title: The Tre2 (USP6) oncogene is a hominoid-specific gene.

PubMed ID: 12604796

DOI: 10.1073/pnas.0437015100

PubMed ID: 8247125

Title: The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene.

PubMed ID: 8247125

DOI: 10.1038/366313a0

PubMed ID: 14521938

Title: Expression in a RabGAP yeast mutant of two human homologues, one of which is an oncogene.

PubMed ID: 14521938

DOI: 10.1016/j.bbrc.2003.09.051

PubMed ID: 12612085

Title: The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling.

PubMed ID: 12612085

DOI: 10.1128/mcb.23.6.2151-2161.2003

PubMed ID: 15026324

Title: USP6 (Tre2) fusion oncogenes in aneurysmal bone cyst.

PubMed ID: 15026324

DOI: 10.1158/0008-5472.can-03-2827

PubMed ID: 15509780

Title: The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6.

PubMed ID: 15509780

DOI: 10.1128/mcb.24.22.9752-9762.2004

PubMed ID: 16127172

Title: Calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease TRE17/USP6.

PubMed ID: 16127172

DOI: 10.1074/jbc.m505220200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20418905

Title: TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaB.

PubMed ID: 20418905

DOI: 10.1038/onc.2010.116

Sequence Information:

  • Length: 1406
  • Mass: 158658
  • Checksum: D3A6822CEB441DB3
  • Sequence:
  • MDMVENADSL QAQERKDILM KYDKGHRAGL PEDKGPEPVG INSSIDRFGI LHETELPPVT 
    AREAKKIRRE MTRTSKWMEM LGEWETYKHS SKLIDRVYKG IPMNIRGPVW SVLLNIQEIK 
    LKNPGRYQIM KERGKRSSEH IHHIDLDVRT TLRNHVFFRD RYGAKQRELF YILLAYSEYN 
    PEVGYCRDLS HITALFLLYL PEEDAFWALV QLLASERHSL PGFHSPNGGT VQGLQDQQEH 
    VVPKSQPKTM WHQDKEGLCG QCASLGCLLR NLIDGISLGL TLRLWDVYLV EGEQVLMPIT 
    SIALKVQQKR LMKTSRCGLW ARLRNQFFDT WAMNDDTVLK HLRASTKKLT RKQGDLPPPA 
    KREQGSLAPR PVPASRGGKT LCKGYRQAPP GPPAQFQRPI CSASPPWASR FSTPCPGGAV 
    REDTYPVGTQ GVPSLALAQG GPQGSWRFLE WKSMPRLPTD LDIGGPWFPH YDFEWSCWVR 
    AISQEDQLAT CWQAEHCGEV HNKDMSWPEE MSFTANSSKI DRQKVPTEKG ATGLSNLGNT 
    CFMNSSIQCV SNTQPLTQYF ISGRHLYELN RTNPIGMKGH MAKCYGDLVQ ELWSGTQKSV 
    APLKLRRTIA KYAPKFDGFQ QQDSQELLAF LLDGLHEDLN RVHEKPYVEL KDSDGRPDWE 
    VAAEAWDNHL RRNRSIIVDL FHGQLRSQVK CKTCGHISVR FDPFNFLSLP LPMDSYMDLE 
    ITVIKLDGTT PVRYGLRLNM DEKYTGLKKQ LRDLCGLNSE QILLAEVHDS NIKNFPQDNQ 
    KVQLSVSGFL CAFEIPVPSS PISASSPTQI DFSSSPSTNG MFTLTTNGDL PKPIFIPNGM 
    PNTVVPCGTE KNFTNGMVNG HMPSLPDSPF TGYIIAVHRK MMRTELYFLS PQENRPSLFG 
    MPLIVPCTVH TRKKDLYDAV WIQVSWLARP LPPQEASIHA QDRDNCMGYQ YPFTLRVVQK 
    DGNSCAWCPQ YRFCRGCKID CGEDRAFIGN AYIAVDWHPT ALHLRYQTSQ ERVVDKHESV 
    EQSRRAQAEP INLDSCLRAF TSEEELGESE MYYCSKCKTH CLATKKLDLW RLPPFLIIHL 
    KRFQFVNDQW IKSQKIVRFL RESFDPSAFL VPRDPALCQH KPLTPQGDEL SKPRILAREV 
    KKVDAQSSAG KEDMLLSKSP SSLSANISSS PKGSPSSSRK SGTSCPSSKN SSPNSSPRTL 
    GRSKGRLRLP QIGSKNKPSS SKKNLDASKE NGAGQICELA DALSRGHMRG GSQPELVTPQ 
    DHEVALANGF LYEHEACGNG CGDGYSNGQL GNHSEEDSTD DQREDTHIKP IYNLYAISCH 
    SGILSGGHYI TYAKNPNCKW YCYNDSSCEE LHPDEIDTDS AYILFYEQQG IDYAQFLPKI 
    DGKKMADTSS TDEDSESDYE KYSMLQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.