Details for: CD1B

Gene ID: 910

Symbol: CD1B

Ensembl ID: ENSG00000158485

Description: CD1b molecule

Associated with

Other Information

Genular Protein ID: 2983657021

Symbol: CD1B_HUMAN

Name: T-cell surface glycoprotein CD1b

UniProtKB Accession Codes:

P29016 Q5TDK9 Q5TDL0 Q9UMM2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 2 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 29 PDBsum 23 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 2447586

Title: Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c.

PubMed ID: 2447586

DOI: 10.1073/pnas.84.24.9189

PubMed ID: 2701945

Title: Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts.

PubMed ID: 2701945

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3097645

Title: Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens.

PubMed ID: 3097645

DOI: 10.1073/pnas.83.23.9154

PubMed ID: 10981968

Title: The alphabeta T cell response to self-glycolipids shows a novel mechanism of CD1b loading and a requirement for complex oligosaccharides.

PubMed ID: 10981968

DOI: 10.1016/s1074-7613(00)00025-x

PubMed ID: 10899914

Title: Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens.

PubMed ID: 10899914

DOI: 10.1084/jem.192.2.281

PubMed ID: 14716313

Title: Saposin C is required for lipid presentation by human CD1b.

PubMed ID: 14716313

DOI: 10.1038/ni1035

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 12118248

Title: Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.

PubMed ID: 12118248

DOI: 10.1038/ni821

PubMed ID: 14764708

Title: The crystal structure of human CD1b with a bound bacterial glycolipid.

PubMed ID: 14764708

DOI: 10.4049/jimmunol.172.4.2382

PubMed ID: 16874306

Title: Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b.

PubMed ID: 16874306

DOI: 10.1038/sj.emboj.7601244

Sequence Information:

  • Length: 333
  • Mass: 36939
  • Checksum: 7D02B670D4DE8CC7
  • Sequence:
    • MLLLPFQLLA VLFPGGNSEH AFQGPTSFHV IQTSSFTNST WAQTQGSGWL DDLQIHGWDS 
DSGTAIFLKP WSKGNFSDKE VAELEEIFRV YIFGFAREVQ DFAGDFQMKY PFEIQGIAGC 
ELHSGGAIVS FLRGALGGLD FLSVKNASCV PSPEGGSRAQ KFCALIIQYQ GIMETVRILL 
YETCPRYLLG VLNAGKADLQ RQVKPEAWLS SGPSPGPGRL QLVCHVSGFY PKPVWVMWMR 
GEQEQQGTQL GDILPNANWT WYLRATLDVA DGEAAGLSCR VKHSSLEGQD IILYWRNPTS 
IGSIVLAIIV PSLLLLLCLA LWYMRRRSYQ NIP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.