Details for: USP10
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.15
Marker Score: 1,260 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.15
Marker Score: 2,377 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.97
Marker Score: 2,382 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.97
Marker Score: 2,101 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.87
Marker Score: 1,965 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.8
Marker Score: 2,423 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.71
Marker Score: 998 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.7
Marker Score: 6,681 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.61
Marker Score: 99,052 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.58
Marker Score: 60,181 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.57
Marker Score: 57,830 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.54
Marker Score: 14,653 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.52
Marker Score: 13,086 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.52
Marker Score: 14,322 - Cell Name: neuron (CL0000540)
Fold Change: 1.52
Marker Score: 6,185 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.51
Marker Score: 22,613 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 1.48
Marker Score: 12,848 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.47
Marker Score: 5,666 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.44
Marker Score: 11,075 - Cell Name: interneuron (CL0000099)
Fold Change: 1.43
Marker Score: 652 - Cell Name: Unknown (CL0002371)
Fold Change: 1.42
Marker Score: 1,511 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.4
Marker Score: 27,761 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 1.38
Marker Score: 1,132 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.36
Marker Score: 5,637 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.35
Marker Score: 13,986 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.35
Marker Score: 2,090 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 1.33
Marker Score: 3,322 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.28
Marker Score: 27,318 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.28
Marker Score: 3,477 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.27
Marker Score: 1,373 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.25
Marker Score: 2,601 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.24
Marker Score: 1,426 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.23
Marker Score: 2,697 - Cell Name: blood cell (CL0000081)
Fold Change: 1.22
Marker Score: 14,173 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 1.21
Marker Score: 2,052 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.21
Marker Score: 586 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.2
Marker Score: 660 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.19
Marker Score: 356 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 1.18
Marker Score: 623 - Cell Name: multi-ciliated epithelial cell (CL0005012)
Fold Change: 1.18
Marker Score: 2,247 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.18
Marker Score: 1,739 - Cell Name: Leydig cell (CL0000178)
Fold Change: 1.18
Marker Score: 1,272 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.18
Marker Score: 1,336 - Cell Name: myelocyte (CL0002193)
Fold Change: 1.17
Marker Score: 506 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.17
Marker Score: 1,466 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.17
Marker Score: 791 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.16
Marker Score: 653 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 1.16
Marker Score: 1,224 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 1.16
Marker Score: 761 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.15
Marker Score: 1,653 - Cell Name: basal cell (CL0000646)
Fold Change: 1.15
Marker Score: 1,483 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.15
Marker Score: 11,555 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.15
Marker Score: 3,118 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 1.14
Marker Score: 1,152 - Cell Name: adventitial cell (CL0002503)
Fold Change: 1.14
Marker Score: 282 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.14
Marker Score: 986 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.14
Marker Score: 17,813 - Cell Name: neural crest cell (CL0011012)
Fold Change: 1.14
Marker Score: 1,215 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.13
Marker Score: 2,652 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.11
Marker Score: 2,138 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.11
Marker Score: 1,021 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.11
Marker Score: 19,684 - Cell Name: Unknown (CL0000548)
Fold Change: 1.1
Marker Score: 802 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 1.09
Marker Score: 328 - Cell Name: ciliated cell (CL0000064)
Fold Change: 1.09
Marker Score: 3,741 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.08
Marker Score: 4,522 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.08
Marker Score: 3,212 - Cell Name: podocyte (CL0000653)
Fold Change: 1.08
Marker Score: 400 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.07
Marker Score: 436 - Cell Name: erythroblast (CL0000765)
Fold Change: 1.07
Marker Score: 671 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.07
Marker Score: 561 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.07
Marker Score: 37,109 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 1.07
Marker Score: 56,593 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.07
Marker Score: 531 - Cell Name: male germ cell (CL0000015)
Fold Change: 1.07
Marker Score: 307 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.06
Marker Score: 708 - Cell Name: hepatocyte (CL0000182)
Fold Change: 1.05
Marker Score: 720 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.05
Marker Score: 394 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.05
Marker Score: 426 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.04
Marker Score: 249 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.04
Marker Score: 3,852 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.04
Marker Score: 4,353 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 1.04
Marker Score: 329 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.04
Marker Score: 921 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.04
Marker Score: 1,253 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 1.03
Marker Score: 362 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.03
Marker Score: 893 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 1.03
Marker Score: 225 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 1.03
Marker Score: 965 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: 1.01
Marker Score: 495 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 1.01
Marker Score: 901 - Cell Name: plasmablast (CL0000980)
Fold Change: 1.01
Marker Score: 1,340 - Cell Name: neutrophil (CL0000775)
Fold Change: 1.01
Marker Score: 614 - Cell Name: ependymal cell (CL0000065)
Fold Change: 1.01
Marker Score: 351 - Cell Name: Schwann cell (CL0002573)
Fold Change: 1.01
Marker Score: 349 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1
Marker Score: 1,422 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 1
Marker Score: 4,295 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1
Marker Score: 2,354 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,589 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.99
Marker Score: 320
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3205072775
Symbol: UBP10_HUMAN
Name: Deubiquitinating enzyme 10
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11439350
Title: Ras-GAP SH3 domain binding protein (G3BP) is a modulator of USP10, a novel human ubiquitin specific protease.
PubMed ID: 11439350
PubMed ID: 8724849
Title: Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.
PubMed ID: 8724849
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17487921
Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.
PubMed ID: 17487921
PubMed ID: 17693683
Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.
PubMed ID: 17693683
PubMed ID: 18632802
Title: Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3.
PubMed ID: 18632802
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18318008
Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.
PubMed ID: 18318008
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19398555
Title: The deubiquitinating enzyme USP10 regulates the post-endocytic sorting of cystic fibrosis transmembrane conductance regulator in airway epithelial cells.
PubMed ID: 19398555
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20096447
Title: USP10 regulates p53 localization and stability by deubiquitinating p53.
PubMed ID: 20096447
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21962518
Title: Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13.
PubMed ID: 21962518
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23279204
Title: Both G3BP1 and G3BP2 contribute to stress granule formation.
PubMed ID: 23279204
DOI: 10.1111/gtc.12023
PubMed ID: 24845384
Title: Deubiquitination and stabilization of T-bet by USP10.
PubMed ID: 24845384
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25861989
Title: TRAF family member-associated NF-kappaB activator (TANK) inhibits genotoxic nuclear factor kappaB activation by facilitating deubiquitinase USP10-dependent deubiquitination of TRAF6 ligase.
PubMed ID: 25861989
PubMed ID: 27022092
Title: G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.
PubMed ID: 27022092
PubMed ID: 32302570
Title: Competing protein-RNA interaction networks control multiphase intracellular organization.
PubMed ID: 32302570
PubMed ID: 32011234
Title: Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized.
PubMed ID: 32011234
DOI: 10.7554/elife.54023
PubMed ID: 31981475
Title: The G3BP1-family-USP10 deubiquitinase complex rescues ubiquitinated 40S subunits of ribosomes stalled in translation from lysosomal degradation.
PubMed ID: 31981475
PubMed ID: 34348161
Title: The E3 ubiquitin ligase RNF10 modifies 40S ribosomal subunits of ribosomes compromised in translation.
PubMed ID: 34348161
PubMed ID: 34469731
Title: iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation.
PubMed ID: 34469731
PubMed ID: 36183834
Title: Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10.
PubMed ID: 36183834
PubMed ID: 37582970
Title: MAVS-loaded unanchored Lys63-linked polyubiquitin chains activate the RIG-I-MAVS signaling cascade.
PubMed ID: 37582970
PubMed ID: 36279435
Title: Yin and yang regulation of stress granules by Caprin-1.
PubMed ID: 36279435
Sequence Information:
- Length: 798
- Mass: 87134
- Checksum: E6BA77E2B5CE2B3F
- Sequence:
MALHSPQYIF GDFSPDEFNQ FFVTPRSSVE LPPYSGTVLC GTQAVDKLPD GQEYQRIEFG VDEVIEPSDT LPRTPSYSIS STLNPQAPEF ILGCTASKIT PDGITKEASY GSIDCQYPGS ALALDGSSNV EAEVLENDGV SGGLGQRERK KKKKRPPGYY SYLKDGGDDS ISTEALVNGH ANSAVPNSVS AEDAEFMGDM PPSVTPRTCN SPQNSTDSVS DIVPDSPFPG ALGSDTRTAG QPEGGPGADF GQSCFPAEAG RDTLSRTAGA QPCVGTDTTE NLGVANGQIL ESSGEGTATN GVELHTTESI DLDPTKPESA SPPADGTGSA SGTLPVSQPK SWASLFHDSK PSSSSPVAYV ETKYSPPAIS PLVSEKQVEV KEGLVPVSED PVAIKIAELL ENVTLIHKPV SLQPRGLINK GNWCYINATL QALVACPPMY HLMKFIPLYS KVQRPCTSTP MIDSFVRLMN EFTNMPVPPK PRQALGDKIV RDIRPGAAFE PTYIYRLLTV NKSSLSEKGR QEDAEEYLGF ILNGLHEEML NLKKLLSPSN EKLTISNGPK NHSVNEEEQE EQGEGSEDEW EQVGPRNKTS VTRQADFVQT PITGIFGGHI RSVVYQQSSK ESATLQPFFT LQLDIQSDKI RTVQDALESL VARESVQGYT TKTKQEVEIS RRVTLEKLPP VLVLHLKRFV YEKTGGCQKL IKNIEYPVDL EISKELLSPG VKNKNFKCHR TYRLFAVVYH HGNSATGGHY TTDVFQIGLN GWLRIDDQTV KVINQYQVVK PTAERTAYLL YYRRVDLL
Genular Protein ID: 2302780509
Symbol: A0A7G6J4N4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 802
- Mass: 87533
- Checksum: CBA33D0F268AEF5A
- Sequence:
MPWLPSPGIG QYIFGDFSPD EFNQFFVTPR SSVELPPYSG TVLCGTQAVD KLPDGQEYQR IEFGVDEVIE PSDTLPRTPS YSISSTLNPQ APEFILGCTA SKITPDGITK EASYGSIDCQ YPGSALALDG SSNVEAEVLE NDGVSGGLGQ RERKKKKKRP PGYYSYLKDG GDDSISTEAL VNGHANSAVP NSVSAEDAEF MGDMPPSVTP RTCNSPQNST DSVSDIVPDS PFPGALGSDT RTAGQPEGGP GADFGQSCFP AEAGRDTLSR TAGAQPCVGT DTTENLGVAN GQILESSGEG TATNGVELHT TESIDLDPTK PESASPPADG TGSASGTLPV SQPKSWASLF HDSKPSSSSP VAYVETKYSP PAISPLVSEK QVEVKEGLVP VSEDPVAIKI AELLENVTLI HKPVSLQPRG LINKGNWCYI NATLQALVAC PPMYHLMKFI PLYSKVQRPC TSTPMIDSFV RLMNEFTNMP VPPKPRQALG DKIVRDIRPG AAFEPTYIYR LLTVNKSSLS EKGRQEDAEE YLGFILNGLH EEMLNLKKLL SPSNEKLTIS NGPKNHSVNE EEQEEQGEGS EDEWEQVGPR NKTSVTRQAD FVQTPITGIF GGHIRSVVYQ QSSKESATLQ PFFTLQLDIQ SDKIRTVQDA LESLVARESV QGYTTKTKQE VEISRRVTLE KLPPVLVLHL KRFVYEKTGG CQKLIKNIEY PVDLEISKEL LSPGVKNKNF KCHRTYRLFA VVYHHGNSAT GGHYTTDVFQ IGLNGWLRID DQTVKVINQY QVVKPTAERT AYLLYYRRVD LL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.