Details for: USP10

Gene ID: 9100

Symbol: USP10

Ensembl ID: ENSG00000103194

Description: ubiquitin specific peptidase 10

Associated with

Other Information

Genular Protein ID: 3205072775

Symbol: UBP10_HUMAN

Name: Deubiquitinating enzyme 10

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11439350

Title: Ras-GAP SH3 domain binding protein (G3BP) is a modulator of USP10, a novel human ubiquitin specific protease.

PubMed ID: 11439350

DOI: 10.1038/sj.onc.1204553

PubMed ID: 8724849

Title: Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 8724849

DOI: 10.1093/dnares/3.1.17

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 17693683

Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.

PubMed ID: 17693683

DOI: 10.1074/mcp.m700120-mcp200

PubMed ID: 18632802

Title: Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3.

PubMed ID: 18632802

DOI: 10.1152/ajprenal.00001.2008

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19398555

Title: The deubiquitinating enzyme USP10 regulates the post-endocytic sorting of cystic fibrosis transmembrane conductance regulator in airway epithelial cells.

PubMed ID: 19398555

DOI: 10.1074/jbc.m109.001685

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20096447

Title: USP10 regulates p53 localization and stability by deubiquitinating p53.

PubMed ID: 20096447

DOI: 10.1016/j.cell.2009.12.032

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21962518

Title: Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13.

PubMed ID: 21962518

DOI: 10.1016/j.cell.2011.08.037

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23279204

Title: Both G3BP1 and G3BP2 contribute to stress granule formation.

PubMed ID: 23279204

DOI: 10.1111/gtc.12023

PubMed ID: 24845384

Title: Deubiquitination and stabilization of T-bet by USP10.

PubMed ID: 24845384

DOI: 10.1016/j.bbrc.2014.05.037

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25861989

Title: TRAF family member-associated NF-kappaB activator (TANK) inhibits genotoxic nuclear factor kappaB activation by facilitating deubiquitinase USP10-dependent deubiquitination of TRAF6 ligase.

PubMed ID: 25861989

DOI: 10.1074/jbc.m115.643767

PubMed ID: 27022092

Title: G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.

PubMed ID: 27022092

DOI: 10.1083/jcb.201508028

PubMed ID: 32302570

Title: Competing protein-RNA interaction networks control multiphase intracellular organization.

PubMed ID: 32302570

DOI: 10.1016/j.cell.2020.03.050

PubMed ID: 32011234

Title: Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized.

PubMed ID: 32011234

DOI: 10.7554/elife.54023

PubMed ID: 31981475

Title: The G3BP1-family-USP10 deubiquitinase complex rescues ubiquitinated 40S subunits of ribosomes stalled in translation from lysosomal degradation.

PubMed ID: 31981475

DOI: 10.1016/j.molcel.2019.12.024

PubMed ID: 34348161

Title: The E3 ubiquitin ligase RNF10 modifies 40S ribosomal subunits of ribosomes compromised in translation.

PubMed ID: 34348161

DOI: 10.1016/j.celrep.2021.109468

PubMed ID: 34469731

Title: iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation.

PubMed ID: 34469731

DOI: 10.1016/j.celrep.2021.109642

PubMed ID: 36183834

Title: Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10.

PubMed ID: 36183834

DOI: 10.1016/j.jbc.2022.102552

PubMed ID: 37582970

Title: MAVS-loaded unanchored Lys63-linked polyubiquitin chains activate the RIG-I-MAVS signaling cascade.

PubMed ID: 37582970

DOI: 10.1038/s41423-023-01065-2

PubMed ID: 36279435

Title: Yin and yang regulation of stress granules by Caprin-1.

PubMed ID: 36279435

DOI: 10.1073/pnas.2207975119

Sequence Information:

  • Length: 798
  • Mass: 87134
  • Checksum: E6BA77E2B5CE2B3F
  • Sequence:
  • MALHSPQYIF GDFSPDEFNQ FFVTPRSSVE LPPYSGTVLC GTQAVDKLPD GQEYQRIEFG 
    VDEVIEPSDT LPRTPSYSIS STLNPQAPEF ILGCTASKIT PDGITKEASY GSIDCQYPGS 
    ALALDGSSNV EAEVLENDGV SGGLGQRERK KKKKRPPGYY SYLKDGGDDS ISTEALVNGH 
    ANSAVPNSVS AEDAEFMGDM PPSVTPRTCN SPQNSTDSVS DIVPDSPFPG ALGSDTRTAG 
    QPEGGPGADF GQSCFPAEAG RDTLSRTAGA QPCVGTDTTE NLGVANGQIL ESSGEGTATN 
    GVELHTTESI DLDPTKPESA SPPADGTGSA SGTLPVSQPK SWASLFHDSK PSSSSPVAYV 
    ETKYSPPAIS PLVSEKQVEV KEGLVPVSED PVAIKIAELL ENVTLIHKPV SLQPRGLINK 
    GNWCYINATL QALVACPPMY HLMKFIPLYS KVQRPCTSTP MIDSFVRLMN EFTNMPVPPK 
    PRQALGDKIV RDIRPGAAFE PTYIYRLLTV NKSSLSEKGR QEDAEEYLGF ILNGLHEEML 
    NLKKLLSPSN EKLTISNGPK NHSVNEEEQE EQGEGSEDEW EQVGPRNKTS VTRQADFVQT 
    PITGIFGGHI RSVVYQQSSK ESATLQPFFT LQLDIQSDKI RTVQDALESL VARESVQGYT 
    TKTKQEVEIS RRVTLEKLPP VLVLHLKRFV YEKTGGCQKL IKNIEYPVDL EISKELLSPG 
    VKNKNFKCHR TYRLFAVVYH HGNSATGGHY TTDVFQIGLN GWLRIDDQTV KVINQYQVVK 
    PTAERTAYLL YYRRVDLL

Genular Protein ID: 2302780509

Symbol: A0A7G6J4N4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 802
  • Mass: 87533
  • Checksum: CBA33D0F268AEF5A
  • Sequence:
  • MPWLPSPGIG QYIFGDFSPD EFNQFFVTPR SSVELPPYSG TVLCGTQAVD KLPDGQEYQR 
    IEFGVDEVIE PSDTLPRTPS YSISSTLNPQ APEFILGCTA SKITPDGITK EASYGSIDCQ 
    YPGSALALDG SSNVEAEVLE NDGVSGGLGQ RERKKKKKRP PGYYSYLKDG GDDSISTEAL 
    VNGHANSAVP NSVSAEDAEF MGDMPPSVTP RTCNSPQNST DSVSDIVPDS PFPGALGSDT 
    RTAGQPEGGP GADFGQSCFP AEAGRDTLSR TAGAQPCVGT DTTENLGVAN GQILESSGEG 
    TATNGVELHT TESIDLDPTK PESASPPADG TGSASGTLPV SQPKSWASLF HDSKPSSSSP 
    VAYVETKYSP PAISPLVSEK QVEVKEGLVP VSEDPVAIKI AELLENVTLI HKPVSLQPRG 
    LINKGNWCYI NATLQALVAC PPMYHLMKFI PLYSKVQRPC TSTPMIDSFV RLMNEFTNMP 
    VPPKPRQALG DKIVRDIRPG AAFEPTYIYR LLTVNKSSLS EKGRQEDAEE YLGFILNGLH 
    EEMLNLKKLL SPSNEKLTIS NGPKNHSVNE EEQEEQGEGS EDEWEQVGPR NKTSVTRQAD 
    FVQTPITGIF GGHIRSVVYQ QSSKESATLQ PFFTLQLDIQ SDKIRTVQDA LESLVARESV 
    QGYTTKTKQE VEISRRVTLE KLPPVLVLHL KRFVYEKTGG CQKLIKNIEY PVDLEISKEL 
    LSPGVKNKNF KCHRTYRLFA VVYHHGNSAT GGHYTTDVFQ IGLNGWLRID DQTVKVINQY 
    QVVKPTAERT AYLLYYRRVD LL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.