Details for: CD1D

Gene ID: 912

Symbol: CD1D

Ensembl ID: ENSG00000158473

Description: CD1d molecule

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 35.6167
    Cell Significance Index: -5.5400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 4.5014
    Cell Significance Index: -5.5500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 2.7883
    Cell Significance Index: 43.1400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.4141
    Cell Significance Index: -5.5800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.2977
    Cell Significance Index: 246.9700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.6449
    Cell Significance Index: 11.9200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6386
    Cell Significance Index: 576.6300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6135
    Cell Significance Index: 36.8300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5452
    Cell Significance Index: 59.3000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5255
    Cell Significance Index: 51.9800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.4613
    Cell Significance Index: 12.3400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4366
    Cell Significance Index: 71.0100
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 0.3336
    Cell Significance Index: 0.8800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2836
    Cell Significance Index: 19.6100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2656
    Cell Significance Index: 12.0400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.2547
    Cell Significance Index: 8.8500
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.2138
    Cell Significance Index: 3.0000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1590
    Cell Significance Index: 4.5800
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.1076
    Cell Significance Index: 0.8900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0757
    Cell Significance Index: 1.6400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0747
    Cell Significance Index: 1.5900
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.0728
    Cell Significance Index: 0.5900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0152
    Cell Significance Index: 1.7900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0128
    Cell Significance Index: 0.4100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0080
    Cell Significance Index: 0.2000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0077
    Cell Significance Index: 0.5000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0021
    Cell Significance Index: -1.5200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0027
    Cell Significance Index: -5.0200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0033
    Cell Significance Index: -5.1000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0035
    Cell Significance Index: -6.4600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0045
    Cell Significance Index: -3.4100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0051
    Cell Significance Index: -6.9700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0079
    Cell Significance Index: -5.7600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0087
    Cell Significance Index: -5.5000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0095
    Cell Significance Index: -5.3300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0095
    Cell Significance Index: -5.2100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0112
    Cell Significance Index: -1.4300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0127
    Cell Significance Index: -5.7500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0139
    Cell Significance Index: -4.9900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0142
    Cell Significance Index: -0.7200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0150
    Cell Significance Index: -1.5300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0176
    Cell Significance Index: -2.4200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0189
    Cell Significance Index: -5.4400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0205
    Cell Significance Index: -0.8400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0213
    Cell Significance Index: -4.2200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0234
    Cell Significance Index: -4.2100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0258
    Cell Significance Index: -5.1700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0261
    Cell Significance Index: -1.3600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0292
    Cell Significance Index: -4.9900
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0294
    Cell Significance Index: -1.2800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0315
    Cell Significance Index: -1.9300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0326
    Cell Significance Index: -3.7400
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0369
    Cell Significance Index: -0.5300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0378
    Cell Significance Index: -5.5000
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0388
    Cell Significance Index: -0.3300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0442
    Cell Significance Index: -5.4300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0455
    Cell Significance Index: -5.3000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0461
    Cell Significance Index: -1.2900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0468
    Cell Significance Index: -6.0500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0520
    Cell Significance Index: -5.4100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0527
    Cell Significance Index: -4.0500
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0723
    Cell Significance Index: -1.0900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0726
    Cell Significance Index: -1.9100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0747
    Cell Significance Index: -1.2500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0785
    Cell Significance Index: -3.6900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0812
    Cell Significance Index: -6.0500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0848
    Cell Significance Index: -5.7000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0922
    Cell Significance Index: -5.6700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0933
    Cell Significance Index: -2.5000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0938
    Cell Significance Index: -2.4100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0951
    Cell Significance Index: -1.0800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0974
    Cell Significance Index: -2.8700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0996
    Cell Significance Index: -1.4700
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.1019
    Cell Significance Index: -1.4900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1032
    Cell Significance Index: -5.4200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1041
    Cell Significance Index: -5.8400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1066
    Cell Significance Index: -4.9700
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1079
    Cell Significance Index: -2.1100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1114
    Cell Significance Index: -2.3100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1180
    Cell Significance Index: -2.4700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1215
    Cell Significance Index: -6.3100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1222
    Cell Significance Index: -1.2700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1238
    Cell Significance Index: -2.0900
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.1300
    Cell Significance Index: -1.4300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1346
    Cell Significance Index: -4.7300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1413
    Cell Significance Index: -6.2500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.1519
    Cell Significance Index: -3.6800
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.1557
    Cell Significance Index: -2.2600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1601
    Cell Significance Index: -5.6100
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.1647
    Cell Significance Index: -2.3600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1657
    Cell Significance Index: -6.2800
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1678
    Cell Significance Index: -2.8500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1704
    Cell Significance Index: -5.5800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1739
    Cell Significance Index: -6.3900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1774
    Cell Significance Index: -5.6500
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.1801
    Cell Significance Index: -2.2800
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1929
    Cell Significance Index: -3.0600
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1964
    Cell Significance Index: -2.6100
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.1993
    Cell Significance Index: -2.7100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1997
    Cell Significance Index: -5.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Lipid Antigen Presentation:** CD1D is specifically involved in the presentation of lipid antigens to T cells, including natural killer T cells (NKT cells) and CD4+ T cells. This process is essential for the activation of immune responses against pathogens and the regulation of immune responses in autoimmune diseases. 2. **Endogenous and Exogenous Lipid Antigens:** CD1D recognizes both endogenous and exogenous lipid antigens, including those derived from fatty acids and glycolipids. This dual functionality allows CD1D to respond to a wide range of lipid antigens, from pathogens to self-antigens. 3. **MHC Class Ib Binding:** CD1D binds to MHC class Ib molecules, facilitating the presentation of lipid antigens to T cells. This interaction is critical for the activation of NKT cells and CD4+ T cells. 4. **Cell Surface Expression:** CD1D is expressed on the surface of various cells, including dendritic cells, monocytes, and epithelial cells. This widespread expression allows CD1D to interact with immune cells and non-immune cells, influencing the immune response. **Pathways and Functions:** 1. **Antigen Processing and Presentation:** CD1D is involved in the processing and presentation of lipid antigens to T cells, which is essential for the activation of immune responses. 2. **Immune Response Regulation:** CD1D regulates immune responses by modulating the activity of NKT cells and CD4+ T cells. Dysregulation of CD1D has been implicated in autoimmune diseases, such as type 1 diabetes and multiple sclerosis. 3. **Innate Immune Response:** CD1D is also involved in the recognition of endogenous and exogenous lipid antigens, influencing the innate immune response. 4. **Cell-Cell Adhesion:** CD1D interacts with cell surface molecules, influencing cell-cell adhesion and the regulation of immune responses. **Clinical Significance:** 1. **Autoimmune Diseases:** Dysregulation of CD1D has been implicated in various autoimmune diseases, including type 1 diabetes, multiple sclerosis, and rheumatoid arthritis. 2. **Infectious Diseases:** CD1D plays a critical role in the recognition of lipid antigens from pathogens, influencing the immune response to infections. 3. **Cancer:** CD1D has been implicated in the progression of certain cancers, including melanoma and lung cancer. 4. **Immunotherapy:** CD1D is a potential target for immunotherapy, as it can be used to modulate the immune response and enhance the efficacy of treatments. In conclusion, the CD1D molecule is a crucial player in the immune system's lipid antigen recognition and processing. Its involvement in the presentation of lipid antigens to T cells, regulation of immune responses, and interaction with cell surface molecules highlights its significance in various diseases. Further research is needed to fully understand the role of CD1D in human health and disease.

Genular Protein ID: 2492849813

Symbol: CD1D_HUMAN

Name: Antigen-presenting glycoprotein CD1d

UniProtKB Accession Codes:

P15813 D3DVD5 Q5W0J3 Q9UMM3 Q9Y5M4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 2 ChEMBL 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 15 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 27 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 21 PDBsum 21 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 3 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 2467814

Title: Two classes of CD1 genes.

PubMed ID: 2467814

DOI: 10.1002/eji.1830190211

PubMed ID: 2463622

Title: Isolation and characterization of a cDNA and gene coding for a fourth CD1 molecule.

PubMed ID: 2463622

DOI: 10.1073/pnas.86.1.252

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10488738

Title: Polymorphism of human CD1 genes.

PubMed ID: 10488738

DOI: 10.1034/j.1399-0039.1999.540202.x

PubMed ID: 3097645

Title: Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens.

PubMed ID: 3097645

DOI: 10.1073/pnas.83.23.9154

PubMed ID: 9973405

Title: A critical tyrosine residue in the cytoplasmic tail is important for CD1d internalization but not for its basolateral sorting in MDCK cells.

PubMed ID: 9973405

PubMed ID: 11927549

Title: Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules.

PubMed ID: 11927549

DOI: 10.1093/emboj/21.7.1650

PubMed ID: 16818729

Title: CD1d ligands: the good, the bad, and the ugly.

PubMed ID: 16818729

DOI: 10.4049/jimmunol.177.2.769

PubMed ID: 17475845

Title: Distinct endosomal trafficking requirements for presentation of autoantigens and exogenous lipids by human CD1d molecules.

PubMed ID: 17475845

DOI: 10.4049/jimmunol.178.10.6181

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 16007090

Title: The crystal structure of human CD1d with and without alpha-galactosylceramide.

PubMed ID: 16007090

DOI: 10.1038/ni1225

PubMed ID: 17581592

Title: CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor.

PubMed ID: 17581592

DOI: 10.1038/nature05907

Sequence Information:

  • Length: 335
  • Mass: 37717
  • Checksum: EA041C1C45A5777F
  • Sequence:
    • MGCLLFLLLW ALLQAWGSAE VPQRLFPLRC LQISSFANSS WTRTDGLAWL GELQTHSWSN 
DSDTVRSLKP WSQGTFSDQQ WETLQHIFRV YRSSFTRDVK EFAKMLRLSY PLELQVSAGC 
EVHPGNASNN FFHVAFQGKD ILSFQGTSWE PTQEAPLWVN LAIQVLNQDK WTRETVQWLL 
NGTCPQFVSG LLESGKSELK KQVKPKAWLS RGPSPGPGRL LLVCHVSGFY PKPVWVKWMR 
GEQEQQGTQP GDILPNADET WYLRATLDVV AGEAAGLSCR VKHSSLEGQD IVLYWGGSYT 
SMGLIALAVL ACLLFLLIVG FTSRFKRQTS YQGVL

Genular Protein ID: 1298351414

Symbol: A0A669KB34_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A669KB34

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 2 Proteomes 2 RefSeq 1 SAM 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 242
  • Mass: 27405
  • Checksum: 7EE9B9FC0FCF118F
  • Sequence:
    • MGCLLFLLLW ALLQAWGSAE VPQRLFPLRC LQISSFANSS WTRTDGLAWL GELQTHSWSN 
DSDTVRSLKP WSQGTFSDQQ WETLQHIFRV YRSSFTRDVK EFAKMLRLSY PLELQVSAGC 
EVHPGNASNN FFHVAFQGKD ILSFQGTSWE PTQEAPLWVN LAIQVLNQDK WTRETVQWLL 
NGTCPQFVSG LLESGKSELK KQGGSYTSMG LIALAVLACL LFLLIVGFTS RFKRQTSYQG 
VL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.