Details for: KCNQ4

Gene ID: 9132

Symbol: KCNQ4

Ensembl ID: ENSG00000117013

Description: potassium voltage-gated channel subfamily Q member 4

Associated with

Other Information

Genular Protein ID: 2485744241

Symbol: KCNQ4_HUMAN

Name: Potassium voltage-gated channel subfamily KQT member 4

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10025409

Title: KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness.

PubMed ID: 10025409

DOI: 10.1016/s0092-8674(00)80556-5

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 10713961

Title: Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors.

PubMed ID: 10713961

DOI: 10.1111/j.1469-7793.2000.t01-2-00349.x

PubMed ID: 11245603

Title: KCNQ4 channels expressed in mammalian cells: functional characteristics and pharmacology.

PubMed ID: 11245603

DOI: 10.1152/ajpcell.2001.280.4.c859

PubMed ID: 23431407

Title: Distinct roles of molecular chaperones HSP90alpha and HSP90beta in the biogenesis of KCNQ4 channels.

PubMed ID: 23431407

DOI: 10.1371/journal.pone.0057282

PubMed ID: 29358396

Title: Centipedes subdue giant prey by blocking KCNQ channels.

PubMed ID: 29358396

DOI: 10.1073/pnas.1714760115

PubMed ID: 17329207

Title: Structural insight into KCNQ (Kv7) channel assembly and channelopathy.

PubMed ID: 17329207

DOI: 10.1016/j.neuron.2007.02.010

PubMed ID: 10369879

Title: Mutations in the KCNQ4 gene are responsible for autosomal dominant deafness in four DFNA2 families.

PubMed ID: 10369879

DOI: 10.1093/hmg/8.7.1321

PubMed ID: 10571947

Title: Novel mutation in the KCNQ4 gene in a large kindred with dominant progressive hearing loss.

PubMed ID: 10571947

DOI: 10.1002/(sici)1098-1004(199912)14:6<493::aid-humu8>3.0.co;2-p

PubMed ID: 10925378

Title: Mutations in the KCNQ4 K+ channel gene, responsible for autosomal dominant hearing loss, cluster in the channel pore region.

PubMed ID: 10925378

DOI: 10.1002/1096-8628(20000731)93:3<184::aid-ajmg4>3.0.co;2-5

PubMed ID: 21242547

Title: Autosomal dominant progressive sensorineural hearing loss due to a novel mutation in the KCNQ4 gene.

PubMed ID: 21242547

DOI: 10.1001/archoto.2010.234

Sequence Information:

  • Length: 695
  • Mass: 77101
  • Checksum: 51390F5E00E8C157
  • Sequence:
  • MAEAPPRRLG LGPPPGDAPR AELVALTAVQ SEQGEAGGGG SPRRLGLLGS PLPPGAPLPG 
    PGSGSGSACG QRSSAAHKRY RRLQNWVYNV LERPRGWAFV YHVFIFLLVF SCLVLSVLST 
    IQEHQELANE CLLILEFVMI VVFGLEYIVR VWSAGCCCRY RGWQGRFRFA RKPFCVIDFI 
    VFVASVAVIA AGTQGNIFAT SALRSMRFLQ ILRMVRMDRR GGTWKLLGSV VYAHSKELIT 
    AWYIGFLVLI FASFLVYLAE KDANSDFSSY ADSLWWGTIT LTTIGYGDKT PHTWLGRVLA 
    AGFALLGISF FALPAGILGS GFALKVQEQH RQKHFEKRRM PAANLIQAAW RLYSTDMSRA 
    YLTATWYYYD SILPSFRELA LLFEHVQRAR NGGLRPLEVR RAPVPDGAPS RYPPVATCHR 
    PGSTSFCPGE SSRMGIKDRI RMGSSQRRTG PSKQHLAPPT MPTSPSSEQV GEATSPTKVQ 
    KSWSFNDRTR FRASLRLKPR TSAEDAPSEE VAEEKSYQCE LTVDDIMPAV KTVIRSIRIL 
    KFLVAKRKFK ETLRPYDVKD VIEQYSAGHL DMLGRIKSLQ TRVDQIVGRG PGDRKAREKG 
    DKGPSDAEVV DEISMMGRVV KVEKQVQSIE HKLDLLLGFY SRCLRSGTSA SLGAVQVPLF 
    DPDITSDYHS PVDHEDISVS AQTLSISRSV STNMD

Genular Protein ID: 1964407486

Symbol: B3KQH8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 356
  • Mass: 39774
  • Checksum: D4E9C75A25EAD9E3
  • Sequence:
  • MPAANLIQAA WRLYSTDMSR AYLTATWYYY DSILPSFREL ALLFEHVQRA RNGGLRPLEV 
    RRAPVPDGAP SRYPPVATCH RPGSTSFCPG ESSRMGIKDR IRMGSSQRRT GPSKQHLAPP 
    TMPTSPSSEQ VGEATSPTKV QKSWSFNDRT RFRASLRLKP RTSAEDAPSE EVAEEKSYQC 
    ELTVDDIMPA VKTVIRSIRI LKFLVAKRKF KETLRPYDVK DVIEQYSAGH LDMLGRIKSL 
    QTRVDQIVGR GPGDRKTREK GDKGPSDAEV VDEISMMGRV VKVEKQVQSI EHKLDLLLGF 
    YSRCLRSGTS ASLGAVQVPL FDPDITSDYH SPVDHEDISV SAQTLSISRS VSTNMD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.