Details for: ATG12
Associated with
Other Information
Genular Protein ID: 834155103
Symbol: ATG12_HUMAN
Name: Ubiquitin-like protein ATG12
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9852036
Title: A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy.
PubMed ID: 9852036
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11096062
Title: The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3.
PubMed ID: 11096062
PubMed ID: 12207896
Title: Mammalian Apg12p, but not the Apg12p.Apg5p conjugate, facilitates LC3 processing.
PubMed ID: 12207896
PubMed ID: 11825910
Title: Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p.
PubMed ID: 11825910
PubMed ID: 16963840
Title: Stimulation of ATG12-ATG5 conjugation by ribonucleic acid.
PubMed ID: 16963840
DOI: 10.4161/auto.3270
PubMed ID: 17457038
Title: Mitochondrial DNA deletions and chloramphenicol treatment stimulate the autophagic transcript ATG12.
PubMed ID: 17457038
DOI: 10.4161/auto.4239
PubMed ID: 17709747
Title: The Atg5-Atg12 conjugate associates with innate antiviral immune responses.
PubMed ID: 17709747
PubMed ID: 18704115
Title: The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series.
PubMed ID: 18704115
PubMed ID: 19074260
Title: Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes.
PubMed ID: 19074260
PubMed ID: 17999726
Title: Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells.
PubMed ID: 17999726
PubMed ID: 19473119
Title: Nicotinamide enhances mitochondria quality through autophagy activation in human cells.
PubMed ID: 19473119
PubMed ID: 19164948
Title: Effect of Helicobacter pylori's vacuolating cytotoxin on the autophagy pathway in gastric epithelial cells.
PubMed ID: 19164948
PubMed ID: 19124466
Title: Regulation of autophagy by the p300 acetyltransferase.
PubMed ID: 19124466
PubMed ID: 19666601
Title: The autophagy machinery is required to initiate hepatitis C virus replication.
PubMed ID: 19666601
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22342342
Title: A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugate.
PubMed ID: 22342342
PubMed ID: 26812546
Title: Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.
PubMed ID: 26812546
DOI: 10.7554/elife.12245
PubMed ID: 23202584
Title: Structure of the human ATG12-ATG5 conjugate required for LC3 lipidation in autophagy.
PubMed ID: 23202584
DOI: 10.1038/nsmb.2431
PubMed ID: 34870550
Title: Adaptor SH3BGRL drives autophagy-mediated chemoresistance through promoting PIK3C3 translation and ATG12 stability in breast cancers.
PubMed ID: 34870550
Sequence Information:
- Length: 140
- Mass: 15113
- Checksum: 109258521C2D194F
- Sequence:
MAEEPQSVLQ LPTSIAAGGE GLTDVSPETT TPEPPSSAAV SPGTEEPAGD TKKKIDILLK AVGDTPIMKT KKWAVERTRT IQGLIDFIKK FLKLVASEQL FIYVNQSFAP SPDQEVGTLY ECFGSDGKLV LHYCKSQAWG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.